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Once perceived as an unimportant occurrence in living organisms, cell degeneration was reconfigured as an important biological phenomenon in development, aging, health, and diseases in the twentieth century. This dissertation tells a twentieth-century history of scientific investigations on cell degeneration, including cell death and aging. By describing four central developments

Once perceived as an unimportant occurrence in living organisms, cell degeneration was reconfigured as an important biological phenomenon in development, aging, health, and diseases in the twentieth century. This dissertation tells a twentieth-century history of scientific investigations on cell degeneration, including cell death and aging. By describing four central developments in cell degeneration research with the four major chapters, I trace the emergence of the degenerating cell as a scientific object, describe the generations of a variety of concepts, interpretations and usages associated with cell death and aging, and analyze the transforming influences of the rising cell degeneration research. Particularly, the four chapters show how the changing scientific practices about cellular life in embryology, cell culture, aging research, and molecular biology of Caenorhabditis elegans shaped the interpretations about cell degeneration in the twentieth-century as life-shaping, limit-setting, complex, yet regulated. These events created and consolidated important concepts in life sciences such as programmed cell death, the Hayflick limit, apoptosis, and death genes. These cases also transformed the material and epistemic practices about the end of cellular life subsequently and led to the formations of new research communities. The four cases together show the ways cell degeneration became a shared subject between molecular cell biology, developmental biology, gerontology, oncology, and pathology of degenerative diseases. These practices and perspectives created a special kind of interconnectivity between different fields and led to a level of interdisciplinarity within cell degeneration research by the early 1990s.
ContributorsJiang, Lijing (Author) / Maienschein, Jane (Thesis advisor) / Laubichler, Manfred (Thesis advisor) / Hurlbut, James (Committee member) / Creath, Richard (Committee member) / White, Michael (Committee member) / Arizona State University (Publisher)
Created2013
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Planned Parenthood, one of the United States' largest providers of reproductive health services, has campaigned for decades to secure women's reproductive rights in the political sphere. However, few scholars have written on the social and political history that preceded the general religious and Republican hostility toward the organization in the

Planned Parenthood, one of the United States' largest providers of reproductive health services, has campaigned for decades to secure women's reproductive rights in the political sphere. However, few scholars have written on the social and political history that preceded the general religious and Republican hostility toward the organization in the twenty-first century. Through Planned Parenthood's growth in the mid-twentieth century, both political parties and many religious organizations pushed for family planning and access to contraception as solutions to population growth and poverty. Arizona was used as a case study to examine the broader context of the shift in the ideas of political parties and religious organizations surrounding the reproductive rights movement from the start of the twentieth century until the 1980s. The historical trajectory of the shifting religious and political support for Planned Parenthood Arizona was demonstrated using both a literature review and archival research. Throughout the early 1900s, Republicans advocated for limited governmental intrusion into citizens' lives, which extended to women's reproduction, where contraception was seen as a private decision between a woman and her doctor. That changed in the late twentieth century when religious concerns exacerbated the political discussion following the legalization of abortion in 1973 and the appointment of Ronald Regan in 1981, one of the first outspoken pro-life presidents. Planned Parenthood faced increasing criticism from religious organizations and the Republican Party. The social and political history surrounding Planned Parenthood Arizona illustrates the interplay between politics and the reproductive rights movement throughout the twentieth century. The contextualization of major historical events during the development of Planned Parenthood Arizona gives insight into the current political and religious beliefs regarding the reproductive rights movement.
ContributorsNunez-Eddy, Claudia Margarita (Author) / Maienschein, Jane (Thesis director) / O'Neil, Erica (Committee member) / Abboud, Alexis (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Jacob D. Green's slave narrative breaks standards surrounding slave narratives and wrote a strong, unique story that allowed his audience to relate to his human characters. His narrative has unprecedented qualities that make his autobiography distinctive. An attempt to locate him in historical documents proved inconclusive and some of his

Jacob D. Green's slave narrative breaks standards surrounding slave narratives and wrote a strong, unique story that allowed his audience to relate to his human characters. His narrative has unprecedented qualities that make his autobiography distinctive. An attempt to locate him in historical documents proved inconclusive and some of his stories elaborated, but his narrative is still a valuable piece of literature that gives historians a glimpse into slavery in the United States and the abolition movement in England.
ContributorsLepore, Amanda Lynn (Author) / Schermerhorn, Calvin (Thesis director) / Soares, Rebecca (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2015-05
Description

Political Notes is a podcast that explores the history of music and musicians over the past several decades and their influence on the political spectrum. Using the case studies of The Chicks and Taylor Swift, Political Notes displays the integration of politics in music and its acceptance by the public,

Political Notes is a podcast that explores the history of music and musicians over the past several decades and their influence on the political spectrum. Using the case studies of The Chicks and Taylor Swift, Political Notes displays the integration of politics in music and its acceptance by the public, giving musicians the power to change the opinions of their listeners. Political Notes exposes a politician's worst nightmare, as we can expect to see a future where musicians collaborate with politicians to help certain individuals get elected and others to be left behind.

ContributorsDubey, Neha (Author) / Schmidt, Peter (Thesis director) / Broberg, Gregory (Committee member) / School of International Letters and Cultures (Contributor) / School of Social Transformation (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The Dynamic Landscape of Abortion Law in the United States explores the ways abortion laws have changed in the United States over the course of US history. Abortion laws in the US have historically been fluid, changing in ways both big and small. Those changes can occur after advances in

The Dynamic Landscape of Abortion Law in the United States explores the ways abortion laws have changed in the United States over the course of US history. Abortion laws in the US have historically been fluid, changing in ways both big and small. Those changes can occur after advances in science, changes in understanding, or changes in public opinion. And there have been various periods in the history of the US where tolerance abortion waxed or waned, and common law reflected those attitudes. Roe v. Wade was a pivotal moment in the history of abortion law that accomplished much in the way of broadening women's access to abortions. But Roe v. Wade was not the beginning or the end of the fight for abortion rights in the US. There were legal abortions prior to Roe v. Wade and illegal abortions after. Roe v. Wade granted that women had a constitutional right to have an abortion but the ruling left the boundaries of that right somewhat undefined and most courtroom battles over abortion laws are fought over where a woman's right to an abortion ends and a States right to regulate and protect fetal life begin. Much change has occurred in abortion laws over the past 50 years, this thesis tracks those changes principally through Supreme Court Cases, such as United States v. Milan Vuitch, Roe v. Wade, and Gonzales v. Planned Parenthood among others. The landscape of abortion law in the US continues to shift today, as recently as 2017 with Plowman v. FMCH cases were being heard in courts that wrought subtle yet important changes in abortion law.
ContributorsHigginbotham, Victoria Ashliegh (Author) / Maienschein, Jane (Thesis director) / Abboud, Alexis (Committee member) / Abboud, Carolina (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Books are constantly changing. For this project I looked at books and how they have changed over time. Starting with just before the Gutenberg Printing Press was invented and ending with the introduction of the Internet this project tracked those changes over time and looked at how they changed how

Books are constantly changing. For this project I looked at books and how they have changed over time. Starting with just before the Gutenberg Printing Press was invented and ending with the introduction of the Internet this project tracked those changes over time and looked at how they changed how people read, who read, and what this said about the people at the time. First, I looked at how books changed physically. At the time of the Gutenberg Printing Press vellum and parchment were being used for the pages of books and illuminated manuscripts made some volumes works of art. Now with the Internet greatly influencing books, that format is radically different. Different materials allowed for books to be made more cheaply and when this happened more people were able to afford them. I also looked at aspects of books like publishing and where the books were sold and how that made a difference in how and why people read. Through all of my research I kept a blog and this allowed me to be almost part of the history and research I was doing. This blog will eventually become an eBook. Books have not only shaped history and people but have been shaped by history. Books are a vital part of helping to spread information and while they will keep changing especially with the Internet, books will never disappear.
ContributorsAdams, Kennedy Rei (Author) / Tebeau, Mark (Thesis director) / Soares, Rebecca (Committee member) / School of Historical, Philosophical and Religious Studies (Contributor) / School of Social Transformation (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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The Norman invasion and conquest of England in 1066, led by Duke William "the Conqueror," is well-known in British history; less well-known is the fact that the conquest caused a group of Norman Jews to immigrate to England. These immigrants were the first significant population of Jews to ever reside

The Norman invasion and conquest of England in 1066, led by Duke William "the Conqueror," is well-known in British history; less well-known is the fact that the conquest caused a group of Norman Jews to immigrate to England. These immigrants were the first significant population of Jews to ever reside in England, and by about 1100, distinct communities of Jews had established themselves in several cities throughout the country. However, Jewish life in England came to an abrupt end less than two-hundred and thirty years after its beginning when King Edward I expelled the entire Jewish population from England in 1290. The edict of expulsion was approved by the English parliament on June 18, 1290, and there are no surviving records of what happened in that meeting or why Edward decided to banish the Jews. Accordingly, there are a host of questions that need answering if one is to propose a explanation. For example, what could compel Edward I, who struggled financially and was deeply in debt for the duration of his reign, to expel the people who had been the crown's greatest asset for two centuries? Why did the king break the charter which specifically placed the Jews under the monarchy's protection? Why was the aristocracy so intent on getting rid of the Jews who, on several occasions, kept the baronies financially afloat through generous loans? My goal in writing this thesis is threefold: first, to provide a concise but clear account of this extraordinarily specific section of history; second, to present the information in such a way that those who read it might be convinced that the Expulsion was, in fact, primarily motivated by financial factors; and third, to identify several structural and institutional factors which were critical to the Jews' experiences in medieval England.
Created2016-12
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In the late nineteenth century, the Comstock Act of 1873 made the distribution of contraception illegal and classified contraception as an obscenity. Reflecting the predominant attitude towards contraception at the time, the Comstock Act was the first federal anti-obscenity law that targeted contraception. However, social acceptance of birth control changed

In the late nineteenth century, the Comstock Act of 1873 made the distribution of contraception illegal and classified contraception as an obscenity. Reflecting the predominant attitude towards contraception at the time, the Comstock Act was the first federal anti-obscenity law that targeted contraception. However, social acceptance of birth control changed at the turn of the twentieth century. In this thesis, I analyzed legislation, advocates, and literature pertinent to that social change to report on the events leading up to the decriminalization of contraception. Because of the complexity of social history, I used legislation and court cases to track pivotal movements that reflected a change in the accessibility and acceptability of birth control. I focused on the efforts of two prominent birth control advocates, Margaret Sanger and Mary Dennett, and analyzed the impact of their efforts in that social movement. I learned that they incited court cases that questioned the validity of the Comstock Act and helped influence societal acceptance of birth control. Through my research, I discovered that the medicalization of contraception influenced its decriminalization and acceptance by society.
ContributorsMalladi, Lakshmeeramya (Author) / Maienschein, Jane (Thesis director) / O'Neil, Erica (Committee member) / Abboud, Alexis (Committee member) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Jane Marion Oppenheimer, embryologist and historian of science and medicine, was born on 19 September 1911 in Philadelphia, Pennsylvania, to Sylvia Stern and James H. Oppenheimer. After studying zoology at Bryn Mawr College, Oppenheimer received her AB degree in 1932. Oppenheimer received her PhD in embryology at Yale University in

Jane Marion Oppenheimer, embryologist and historian of science and medicine, was born on 19 September 1911 in Philadelphia, Pennsylvania, to Sylvia Stern and James H. Oppenheimer. After studying zoology at Bryn Mawr College, Oppenheimer received her AB degree in 1932. Oppenheimer received her PhD in embryology at Yale University in 1935 and worked as a research fellow from 1935-1936. While at Yale she was influenced by the work of Ross Granville Harrison and John Spangler Nicholas, the latter of whom was Oppenheimer's PhD advisor. While working with Nicholas, she studied the embryology of killifish (Fundulus hereoclitus) using Nicholas s method for dechorionating the embryo, which made it possible to perform precise experimental manipulations on teleost embryos. Oppenheimer became interested in teleosts after studying the history of biology as a graduate student and published a part of her dissertation, "Historical Introduction to the Study of Teleostean Development," in the History of Science Society journal Osiris. From 1934-1937 she published numerous noteworthy papers discussing Fundulus embryology. Oppenheimer performed fate mapping experiments and developed a staging series for Fundulus embryos. When the United States and the USSR developed Apollo-Soyuz as a joint space venture, Oppenheimer used Fundulus embryos to design an experiment that tested the effects of a zero-gravity environment on embryonic development.

Created2007-11-01
Description
Scientific researchers have studied microorganisms since the emergence of the single lens microscope in the 17th century. Since then, researchers designed and published many thousands of images to record and share their observations, including hand-drawn diagrams, photomicrographs, and photographs. Images shaped how researchers conceived of microorganisms, their concepts of microorganisms

Scientific researchers have studied microorganisms since the emergence of the single lens microscope in the 17th century. Since then, researchers designed and published many thousands of images to record and share their observations, including hand-drawn diagrams, photomicrographs, and photographs. Images shaped how researchers conceived of microorganisms, their concepts of microorganisms shaped their images, and their images and concepts were shaped by the contexts in which they were working. Over time, the interplay of images and concepts in various research contexts participated in the development of new concepts related to microorganisms, like the “biofilm” concept, or the idea that bacteria exist in nature as complex aggregates attached to surfaces via extracellular polymeric matrices. Many histories of microbiology locate the origin of the biofilm concept in the 1970s, but that date obscures the rich history of research about attached microbial aggregates that occurred throughout the history of microbiology. I discovered how the interplay of images and concepts related to bacteria participated in the development of the biofilm concept by documenting when and why researchers used different visual features to represent changing concepts related to microorganisms. I specifically examined how and why scientists represented evolving concepts related to bacteria during the 17th century (Chapter 1), from the late 17th century to the early 20th century (Chapter 2), and during the first seventy-four years of the 20th century (Chapter 3). I discovered the biofilm concept developed in at least three unique research contexts during the 20th century, and how images reflected and shaped the concept’s development in each case. The narrative and collection of images generated from this work serve as a visual history of the development of scientists’ ideas about the nature of bacteria over 300 years.
ContributorsGuerrero, Anna Clemencia (Author) / Maienschein, Jane (Thesis advisor) / Laubichler, Manfred (Committee member) / Sterner, Beckett (Committee member) / Matlin, Karl (Committee member) / Arizona State University (Publisher)
Created2023