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Description
Understanding changes and trends in biomedical knowledge is crucial for individuals, groups, and institutions as biomedicine improves people’s lives, supports national economies, and facilitates innovation. However, as knowledge changes what evidence illustrates knowledge changes? In the case of microbiome, a multi-dimensional concept from biomedicine, there are significant increases in publications, citations, funding, collaborations, and other explanatory variables or contextual factors. What is observed in the microbiome, or any historical evolution of a scientific field or scientific knowledge, is that these changes are related to changes in knowledge, but what is not understood is how to measure and track changes in knowledge. This investigation highlights how contextual factors from the language and social context of the microbiome are related to changes in the usage, meaning, and scientific knowledge on the microbiome. Two interconnected studies integrating qualitative and quantitative evidence examine the variation and change of the microbiome evidence are presented. First, the concepts microbiome, metagenome, and metabolome are compared to determine the boundaries of the microbiome concept in relation to other concepts where the conceptual boundaries have been cited as overlapping. A collection of publications for each concept or corpus is presented, with a focus on how to create, collect, curate, and analyze large data collections. This study concludes with suggestions on how to analyze biomedical concepts using a hybrid approach that combines results from the larger language context and individual words. Second, the results of a systematic review that describes the variation and change of microbiome research, funding, and knowledge are examined. A corpus of approximately 28,000 articles on the microbiome are characterized, and a spectrum of microbiome interpretations are suggested based on differences related to context. The collective results suggest the microbiome is a separate concept from the metagenome and metabolome, and the variation and change to the microbiome concept was influenced by contextual factors. These results provide insight into how concepts with extensive resources behave within biomedicine and suggest the microbiome is possibly representative of conceptual change or a preview of new dynamics within science that are expected in the future.
ContributorsAiello, Kenneth (Author) / Laubichler, Manfred D (Thesis advisor) / Simeone, Michael (Committee member) / Buetow, Kenneth (Committee member) / Walker, Sara I (Committee member) / Arizona State University (Publisher)
Created2018
Description
This dissertation examines automobile title lending practices to interrogate debt as an embodied experience. Alternative financial services such as title lending provide a way to link socio-economic inequality to instruments of financial debt. The predominant research on inequality focuses on wage, income, and asset wealth; rarely is a direct connection made between socio-economic inequality and the object of debt. My interest lies beyond aggregate amounts of debt to also consider the ways in which different bodies have access to different forms of debt. This project examines how particular subprime instruments work to reinforce structural inequalities associated with race, class, and gender and how specific populations are increasingly coming to rely on debt to subsist. Using in-depth interviews, geospatial mapping, and descriptive statistical analysis I show the importance of recognizing debt not only as a conditional object but also as a lived condition of being. I conclude with discussions on dispossession and financial precarity to consider how the normative discourse of debt needs to change.
ContributorsSugata, Michihiro (Author) / Quan, H.L.T. (Thesis advisor) / Talebi, Shahla (Committee member) / Catlaw, Thomas (Committee member) / Arizona State University (Publisher)
Created2016
Description
In an environment in which public values are often surrendered for market ones, the administration of public housing has increasingly devolved construction, management, and even ownership responsibilities to the private sector to cut costs. There is little known about private management practices at public housing sites and how they shape the lives of its residents - half of whom are growing numbers of seniors and people with disabilities who are aging in place. This multi-site comparative case study involves three public housing sites that serve seniors and people with disabilities: one is privately-managed, one is publicly-managed, and one is privately-managed with public case management through the HOPE VI program. The intent of this comparison is to determine if there is a difference in management response by sector and whether differences pose a challenge to social equity.
Results indicate that there were social equity failures across all three sites with the private sites experiencing the most barriers for residents. The power-knowledge structure and perceptions of the residents shaped the institutions or staffing, services, policies, and amenities that either empowered the residents by helping them build a cohesive community; or it subjugated them by not offering space for community-building. In response, many residents' actions and beliefs were shaped by these institutions; however, in the face of resistance to management practices, they often exercised power through self-governing to achieve the satisfaction they desired. Recognizing that residents can exercise their own power, community resiliency to support aging in place may be achieved by supporting resident needs and drawing upon their expertise, assistance, and influential power to build stronger housing communities - an option with low costs but great gains. But in order to do so, the power-knowledge structure must be influenced to support this goal. This research describes the governance of public housing and the responses and relationships of both management and residents in these newly created public spaces. It then presents a model that can foster change in resident engagement and network building to support aging in place, and advance social and community resiliency, regardless of sector.
Results indicate that there were social equity failures across all three sites with the private sites experiencing the most barriers for residents. The power-knowledge structure and perceptions of the residents shaped the institutions or staffing, services, policies, and amenities that either empowered the residents by helping them build a cohesive community; or it subjugated them by not offering space for community-building. In response, many residents' actions and beliefs were shaped by these institutions; however, in the face of resistance to management practices, they often exercised power through self-governing to achieve the satisfaction they desired. Recognizing that residents can exercise their own power, community resiliency to support aging in place may be achieved by supporting resident needs and drawing upon their expertise, assistance, and influential power to build stronger housing communities - an option with low costs but great gains. But in order to do so, the power-knowledge structure must be influenced to support this goal. This research describes the governance of public housing and the responses and relationships of both management and residents in these newly created public spaces. It then presents a model that can foster change in resident engagement and network building to support aging in place, and advance social and community resiliency, regardless of sector.
ContributorsMcFadden, Erica S (Author) / Lucio, Joanna (Thesis advisor) / Catlaw, Thomas (Committee member) / Klein, Jay (Committee member) / Schugurensky, Daniel, 1958- (Committee member) / Arizona State University (Publisher)
Created2014
Description
In 2001, a refugee group of unaccompanied minors known as the Lost Boys of Sudan began arriving in the United States. Their early years were met with extensive media coverage and scores of well-meaning volunteers in scattered resettlement locations across the country. Their story was told in television news reports, documentary films, and published memoirs. Updates regularly appeared in newsprint media. Scholars have criticized public depictions of refugees as frequently de-politicized, devoid of historical context, and often depicting voiceless masses of humanity rather than individuals with skills and histories (Malkki 1996, Harrell-Bond and Voutira 2007). These representations matter because they are both shaped by and shape what is possible in public discourse and everyday relations. This dissertation research creates an intersection where public representation and everyday practices meet. Through participant observation as a volunteer at a refugee community center in Phoenix, Arizona, this research explores the emotions, social roles and relations that underpin community formation, and investigates the narratives, representations, and performances that local Lost Boys and their publics engage in. I take the assertion that "refugee issues are one privileged site for the study of humanitarian interventions through which 'the international community' constitutes itself " (Malkki 1996: 378) and consider formation of local 'communities of feeling' (Riches and Dawson 1996) in order to offer a critique of humanitarianism as mobilized and enacted around the Lost Boys.
ContributorsAlexander, Melinda (Author) / McHugh, Kevin (Thesis advisor) / Catlaw, Thomas (Committee member) / Lukinbeal, Christopher (Committee member) / Menjivar, Cecilia (Committee member) / Arizona State University (Publisher)
Created2014