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The purpose of this project was to establish a digital and social media presence to support a personal fitness trainer and d�TERRA essential oils wellness advocate in growing her health and wellness businesses. The first portion explores the role of digital and social media tools for health and wellness professionals.

The purpose of this project was to establish a digital and social media presence to support a personal fitness trainer and d�TERRA essential oils wellness advocate in growing her health and wellness businesses. The first portion explores the role of digital and social media tools for health and wellness professionals. It incorporates use of both secondary and primary research methods including focus groups and in-depth interviews. The second portion is a campaign proposal that serves as a creative response to the research and findings of the first portion. The proposal includes recommendations for strategic use of new brand building and social networking tools such as a personal website, Facebook, Twitter, LinkedIn and About.Me pages. It also offers collateral material for brand outreach, social media calendars and a 10-page social media guidebook offering suggestions on how to strategically implement the campaign elements.
ContributorsNichols, Emily Jaye (Author) / Wu, Xu (Thesis director) / Roschke, Kristy (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor)
Created2015-05
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Social media is an increasingly pertinent facet of popular culture. Research has found that a rape culture, a culture that tolerates and condones sexual assault, is evident in many forms of pop culture. This study looks at the way sexual assault is discussed in social media through an examination of

Social media is an increasingly pertinent facet of popular culture. Research has found that a rape culture, a culture that tolerates and condones sexual assault, is evident in many forms of pop culture. This study looks at the way sexual assault is discussed in social media through an examination of Internet memes, trends and images that go viral online. The study found that there is evidence to belief a rape culture exists online. It offers solutions for decreasing incidences of gender-based attacks online.
Created2014-12
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Description
Social media is an industry that is rapidly growing and is affecting our society, our health, and our social environments. Emerging research suggests that Social Media has been linked to Poor Body Image, Cyberbullying, Depression, Internet Addiction, and Loneliness among other things. This paper looks at the research and discusses

Social media is an industry that is rapidly growing and is affecting our society, our health, and our social environments. Emerging research suggests that Social Media has been linked to Poor Body Image, Cyberbullying, Depression, Internet Addiction, and Loneliness among other things. This paper looks at the research and discusses the designer's role in the matter. Is it possible that poor design is the cause of these problems? Can design solve these problems? Are there ethical standards that digital product designers in particular can abide by?
ContributorsDavis, Nicole Angela (Author) / Sanft, Alfred (Thesis director) / Heywood, William (Committee member) / Barrett, The Honors College (Contributor) / The Design School (Contributor)
Created2014-05
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Description
The purpose of this project was to examine the viability of protein biomarkers in pre-symptomatic detection of lung cancer. Regular screening has been shown to vastly improve patient survival outcome. Lung cancer currently has the highest occurrence and mortality of all cancers and so a means of screening would be

The purpose of this project was to examine the viability of protein biomarkers in pre-symptomatic detection of lung cancer. Regular screening has been shown to vastly improve patient survival outcome. Lung cancer currently has the highest occurrence and mortality of all cancers and so a means of screening would be highly beneficial. In this research, the biomarker neuron-specific enolase (Enolase-2, eno2), a marker of small-cell lung cancer, was detected at varying concentrations using electrochemical impedance spectroscopy in order to develop a mathematical model of predicting protein expression based on a measured impedance value at a determined optimum frequency. The extent of protein expression would indicate the possibility of the patient having small-cell lung cancer. The optimum frequency was found to be 459 Hz, and the mathematical model to determine eno2 concentration based on impedance was found to be y = 40.246x + 719.5 with an R2 value of 0.82237. These results suggest that this approach could provide an option for the development of small-cell lung cancer screening utilizing electrochemical technology.
ContributorsEvans, William Ian (Author) / LaBelle, Jeffrey (Thesis director) / Spano, Mark (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
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Description
BACKGROUND: Biotechnology can improve vitamin deficiencies, farming practices and yields, yet it is surrounded by controversy. PURPOSE: The purpose of this study was to better understand opinions Americans have about genetically modified organisms (GMOs), across multiple perspectives including scientists, farmers, and perceptions shared via social media. METHODS: A Google Scholar

BACKGROUND: Biotechnology can improve vitamin deficiencies, farming practices and yields, yet it is surrounded by controversy. PURPOSE: The purpose of this study was to better understand opinions Americans have about genetically modified organisms (GMOs), across multiple perspectives including scientists, farmers, and perceptions shared via social media. METHODS: A Google Scholar search for the term "genetically modified" (GM) produced 1,420,000 results in 0.05 seconds from the year 1988 to present, a portion of this literature was used for this study. In addition a quasi-experimental study on social media (i.e. a blog and Twitter) was performed to inspire reactions of social media users who followed the accounts @Biofortified and @BiotechFood. The study lasted for approximately three months. The analytics website, Topsy was also used to track the number of conversations that included terms like "GMO". Furthermore a plant biologist, sustainability scientist, and local farmers were interviewed to gain insights on their perceptions of GM products. RESULTS: Results generally suggest that there was no stance shared by social media users, local farmers, and researchers. It was clear however that conversation about GMOs happens daily on social media. These conversations however lack the evidence that can be learned through literature and conversations with local farmers. DISCUSSION: A plausible possible reason for the confusion and mixed opinions is that regardless of the resources (like scientific literature and agriculture workers available on GMOs), individuals appear to use moral reasoning \u2014 as defined by Jonathan Haidt \u2014 to defend their stance on GMOs, not necessarily any empirical evidence.
ContributorsHubbard, Shayla Briann (Author) / Hekler, Eric (Thesis director) / Wharton, Christopher (Committee member) / Barrett, The Honors College (Contributor) / School of Community Resources and Development (Contributor) / School of Public Affairs (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
Introduction: Human papillomavirus (HPV) infection is seen in up to 90% of cases of cervical cancer, the third leading cancer cause of death in women. Current HPV screening focuses on only two HPV types and covers roughly 75% of HPV-associated cervical cancers. A protein based assay to test for antibody

Introduction: Human papillomavirus (HPV) infection is seen in up to 90% of cases of cervical cancer, the third leading cancer cause of death in women. Current HPV screening focuses on only two HPV types and covers roughly 75% of HPV-associated cervical cancers. A protein based assay to test for antibody biomarkers against 98 HPV antigens from both high and low risk types could provide an inexpensive and reliable method to screen for patients at risk of developing invasive cervical cancer. Methods: 98 codon optimized, commercially produced HPV genes were cloned into the pANT7_cGST vector, amplified in a bacterial host, and purified for mammalian expression using in vitro transcription/translation (IVTT) in a luminescence-based RAPID ELISA (RELISA) assay. Monoclonal antibodies were used to determine immune cross-reactivity between phylogenetically similar antigens. Lastly, several protein characteristics were examined to determine if they correlated with protein expression. Results: All genes were successfully moved into the destination vector and 86 of the 98 genes (88%) expressed protein at an adequate level. A difference was noted in expression by gene across HPV types but no correlation was found between protein size, pI, or aliphatic index and expression. Discussion: Further testing is needed to express the remaining 12 HPV genes. Once all genes have been successfully expressed and purified at high concentrations, DNA will be printed on microscope slides to create a protein microarray. This microarray will be used to screen HPV-positive patient sera for antibody biomarkers that may be indicative of cervical cancer and precancerous cervical neoplasias.
ContributorsMeshay, Ian Matthew (Author) / Anderson, Karen (Thesis director) / Magee, Mitch (Committee member) / Katchman, Benjamin (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality in the USA and throughout the world. Two phenotypes that promote this deadly outcome are the invasive potential of NSCLC and the emergence of therapeutic resistance in this disease. There is an unmet clinical need to understand the

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality in the USA and throughout the world. Two phenotypes that promote this deadly outcome are the invasive potential of NSCLC and the emergence of therapeutic resistance in this disease. There is an unmet clinical need to understand the mechanisms that govern NSCLC cell invasion and therapeutic resistance, and to target these phenotypes towards abating the dismal five-year survival of NSCLC. The expression of the tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A; Fn14) correlates with poor patient survival and invasiveness in many tumor types including NSCLC. We hypothesize that suppression of Fn14 will inhibit NSCLC cell motility and reduce cell viability. Here we demonstrate that atorvastatin calcium treatment reduces Fn14 expression in NSCLC cell lines. Prior to Fn14 protein suppression, atorvastatin calcium modulated the expression of the Fn14 modulators P-ERK1/2 and P-NF-κβ. Atorvastatin calcium treatment inhibited the migratory capacity in H1975, H2030 and H1993 cells by at least 55%. When chemotactic migration in H2030 cells was induced by the Fn14 ligand TNF-like weak inducer of apoptosis (TWEAK) treatment, atorvastatin calcium successfully negated any stimulatory effects. Inversely, treatment of NSCLC cells with cholesterol resulted in a statistically significant increase in migration. Depletion of Fn14 expression via siRNA suppressed the migratory effect of cholesterol. Finally, atorvastatin calcium treatment sensitized cells to radiation treatment, reducing cell survival. These data suggest that atorvastatin calcium may inhibit NSCLC invasiveness through a mechanism involving Fn14, and may be a novel therapeutic target in NSCLC tumors expressing Fn14.
ContributorsCornes, Victoria Elisabeth (Author) / Stout, Valerie (Thesis director) / Whitsett, Timothy (Committee member) / Carson, Vashti (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
The purpose of this thesis study was to examine whether the "war on cancer" metaphor influences cancer perception and treatment decision. A total of 249 undergraduates (152 females) from a large southwestern university participated in an online survey experiment and were either randomly assigned to the control condition (N=123) or

The purpose of this thesis study was to examine whether the "war on cancer" metaphor influences cancer perception and treatment decision. A total of 249 undergraduates (152 females) from a large southwestern university participated in an online survey experiment and were either randomly assigned to the control condition (N=123) or to the war prime condition (N=126). Participants in the control condition did not receive the metaphor manipulation while participants in the war prime condition received the subtle "war on cancer" metaphor prime. After the prime was given, participants read a scenario, answered questions related to the situation, and responded to demographic questions. The results suggested that, compared to participants in the no-prime condition, participants exposed to the war metaphor were more likely to (a) view melanoma as an acute disease, (b) choose chemotherapy over molecular tests, and (c) prefer more aggressive treatment. These findings illustrated the unintended consequences of the "war on cancer" slogan. The results were encouraging and in the predicted direction, but the effect size was small. The discussion section described possible future directions for research.
ContributorsShangraw, Ann Mariah (Author) / Kwan, Virginia (Thesis director) / Neuberg, Steven (Committee member) / Cavanaugh Toft, Carolyn (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2015-05
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Description
This thesis explores how we can harness new technology to improve our relationship with companion animals and promote shelter animal welfare. The study looked into using the photo-sharing application Instagram to increase adoption rates at the Arizona Animal Welfare League & SPCA. An Instagram page was created and managed for

This thesis explores how we can harness new technology to improve our relationship with companion animals and promote shelter animal welfare. The study looked into using the photo-sharing application Instagram to increase adoption rates at the Arizona Animal Welfare League & SPCA. An Instagram page was created and managed for the shelter, and data was collected regarding the impact the page had on adoption rates. The results were mixed, but overall it was determined that the Instagram page has unique value for the shelter.
ContributorsBautista-Hobin, Elena Maria (Author) / Minteer, Ben (Thesis director) / Ellison, Karin (Committee member) / Morefield, Michael (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
The selfie craze has taken over smartphone users. Despite a wealth of published opinion pieces on the matter, there lacks a constructive and academically-based dialogue about selfies. "Presentation of Selfie" is a creative, interactive space that analyzes a sample of collected selfies. The project takes a look at how age,

The selfie craze has taken over smartphone users. Despite a wealth of published opinion pieces on the matter, there lacks a constructive and academically-based dialogue about selfies. "Presentation of Selfie" is a creative, interactive space that analyzes a sample of collected selfies. The project takes a look at how age, relationships and identities play a role in the social significance of selfie culture.
ContributorsJeffords, Alison Rae (Author) / McGibbney-Vlahoulis, Michelle (Thesis director) / Leong, Karen (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor) / Department of Marketing (Contributor)
Created2015-05