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Description
This project was centered around designing a processor model (using the C programming language) based on the Coldfire computer architecture that will run on third party software known as Open Virtual Platforms. The end goal is to have a fully functional processor that can run Coldfire instructions and utilize peripheral devices in the same way as the hardware used in the embedded systems lab at ASU. This project would cut down the substantial amount of time students spend commuting to the lab. Having the processor directly at their disposal would also encourage them to spend more time outside of class learning the hardware and familiarizing themselves with development on an embedded micro-controller. The model will be accurate, fast and reliable. These aspects will be achieved through rigorous unit testing and use of the OVP platform which provides instruction accurate simulations at hundreds of MIPS (million instructions per second) for the specified model. The end product was able to accurately simulate a subset of the Coldfire instructions at very high rates.
ContributorsDunning, David Connor (Author) / Burger, Kevin (Thesis director) / Meuth, Ryan (Committee member) / Barrett, The Honors College (Contributor) / Computer Science and Engineering Program (Contributor)
Created2014-12
Big Data Network Analysis of Genetic Variation and Gene Expression in Individuals with Breast Cancer
Description
The advent of big data analytics tools and frameworks has allowed for a plethora of new approaches to research and analysis, making data sets that were previously too large or complex more accessible and providing methods to collect, store, and investigate non-traditional data. These tools are starting to be applied in more creative ways, and are being used to improve upon traditional computation methods through distributed computing. Statistical analysis of expression quantitative trait loci (eQTL) data has classically been performed using the open source tool PLINK - which runs on high performance computing (HPC) systems. However, progress has been made in running the statistical analysis in the ecosystem of the big data framework Hadoop, resulting in decreased run time, reduced storage footprint, reduced job micromanagement and increased data accessibility. Now that the data can be more readily manipulated, analyzed and accessed, there are opportunities to use the modularity and power of Hadoop to further process the data. This project focuses on adding a component to the data pipeline that will perform graph analysis on the data. This will provide more insight into the relation between various genetic differences in individuals with breast cancer, and the resulting variation - if any - in gene expression. Further, the investigation will look to see if there is anything to be garnered from a perspective shift; applying tools used in classical networking contexts (such as the Internet) to genetically derived networks.
ContributorsRandall, Jacob Christopher (Author) / Buetow, Kenneth (Thesis director) / Meuth, Ryan (Committee member) / Almalih, Sara (Committee member) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
5G Millimeter Wave (mmWave) technology holds great promise for Connected Autonomous Vehicles (CAVs) due to its ability to achieve data rates in the Gbps range. However, mmWave suffers high beamforming overhead and requirement of line of sight (LOS) to maintain a strong connection. For Vehicle-to-Infrastructure (V2I) scenarios, where CAVs connect to roadside units (RSUs), these drawbacks become apparent. Because vehicles are dynamic, there is a large potential for link blockages, which in turn is detrimental to the connected applications running on the vehicle, such as cooperative perception and remote driver takeover. Existing RSU selection schemes base their decisions on signal strength and vehicle trajectory alone, which is not enough to prevent the blockage of links. Most recent CAVs motion planning algorithms routinely use other vehicle's near-future plans, either by explicit communication among vehicles, or by prediction. In this thesis, I make use of this knowledge (of the other vehicle's near future path plans) to further improve the RSU association mechanism for CAVs. I solve the RSU association problem by converting it to a shortest path problem with the objective to maximize the total communication bandwidth.
Evaluations of B-AWARE in simulation using Simulated Urban Mobility (SUMO) and Digital twin for self-dRiving Intelligent VEhicles (DRIVE) on 12 highway and city street scenarios with varying traffic density and RSU placements show that B-AWARE results in a 1.05x improvement of the potential datarate in the average case and 1.28x in the best case vs. the state of the art. But more impressively, B-AWARE reduces the time spent with no connection by 48% in the average case and 251% in the best case as compared to the state-of-the-art methods. This is partly a result of B-AWARE reducing almost 100% of blockage occurrences in simulation.
ContributorsSzeto, Matthew (Author) / Shrivastava, Aviral (Thesis advisor) / LiKamWa, Robert (Committee member) / Meuth, Ryan (Committee member) / Arizona State University (Publisher)
Created2023
Description
Immunotherapy is an effective treatment for cancer which enables the patient's immune system to recognize tumor cells as pathogens. In order to design an individualized treatment, the t cell receptors (TCR) which bind to a tumor's unique antigens need to be determined. We created a convolutional neural network to predict the binding affinity between a given TCR and antigen to enable this.
ContributorsCai, Michael Ray (Author) / Lee, Heewook (Thesis director) / Meuth, Ryan (Committee member) / Computer Science and Engineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-12