Matching Items (22)
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- All Subjects: Cancer
- Creators: Department of Psychology
Description
This purpose of this thesis study was to examine variables of the "War on Cancer" frame, loss-gain prime, and patient gender on treatment decision for advanced cancer patients. A total of 291 participants (141 females) participated in an online survey experiment and were randomly assigned to one of eight possible conditions, each of which were comprised of a combination of one of two levels for three total independent variables: war frame ("War on Cancer" frame or neutral frame), loss-gain prime (loss prime or gain prime), and patient gender (female or male). Each of the three variables were operationalized to determine whether or not the exposure to the war on cancer paradigm, loss-frame language, or male patient gender would increase the likelihood of a participant choosing a more aggressive cancer treatment. Participants read a patient scenario and were asked to respond to questions related to motivating factors. Participants were then asked to report preference for one of two treatment decisions. Participants were then asked to provide brief demographic information in addition to responding to questions about military history, war attitudes, and cancer history. The aforementioned manipulations sought to determine whether exposure to various factors would make a substantive difference in final treatment decision. Contrary to the predicted results, participants in the war frame condition (M = 3.85, SD = 1.48) were more likely to choose the pursuit of palliative care (as opposed to aggressive treatment) than participants in the neutral frame condition (M = 3.54, SD = 1.23). Ultimately, these significant findings suggest that there is practical information to be gained from treatment presentation manipulations. By arming healthcare providers with a more pointed understanding of the nuances of treatment presentation, we can hope to empower patients, their loved ones, and healthcare providers entrenched in the world of cancer treatment.
ContributorsKnowles, Madelyn Ann (Author) / Kwan, Virginia S. Y. (Thesis director) / Presson, Clark (Committee member) / Salamone, Damien (Committee member) / Department of Psychology (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The purpose of this thesis study was to examine whether the "war on cancer" metaphor influences cancer perception and treatment decision. A total of 249 undergraduates (152 females) from a large southwestern university participated in an online survey experiment and were either randomly assigned to the control condition (N=123) or to the war prime condition (N=126). Participants in the control condition did not receive the metaphor manipulation while participants in the war prime condition received the subtle "war on cancer" metaphor prime. After the prime was given, participants read a scenario, answered questions related to the situation, and responded to demographic questions. The results suggested that, compared to participants in the no-prime condition, participants exposed to the war metaphor were more likely to (a) view melanoma as an acute disease, (b) choose chemotherapy over molecular tests, and (c) prefer more aggressive treatment. These findings illustrated the unintended consequences of the "war on cancer" slogan. The results were encouraging and in the predicted direction, but the effect size was small. The discussion section described possible future directions for research.
ContributorsShangraw, Ann Mariah (Author) / Kwan, Virginia (Thesis director) / Neuberg, Steven (Committee member) / Cavanaugh Toft, Carolyn (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
Police use of force has become a topic of national discussion, particularly in the wake of the deaths of Michael Brown and Eric Garner. Currently, the focus seems to be on individual officers and their individual attitudes and beliefs. Given that use of force is an individual decision it is intuitive to think that an officer's decision to use force would be impacted by his or her attitudes and beliefs. This reasoning ignores the larger social and organizational contexts within which police officers are situated. Specifically, an officer's peer culture and department may exert control over his or her attitudes and behaviors regarding use of force. The purpose of the current study is to determine whether these larger social contexts impact an individual's perceptions regarding use of force. Using data from a nationally representative survey sample, the study finds that individual attitudes significantly predict officers' willingness to report another officer's excessive use of force. However, this relationship weakens when including measures of peer culture and departmental influence. These findings suggest that perceptions of use of force are influenced by more than just individual attitudes towards use of force. Limitations and future research suggestions are discussed.
ContributorsMorse, Stephanie Jean (Author) / Wright, Kevin (Thesis director) / Ready, Justin (Committee member) / Barrett, The Honors College (Contributor) / School of Criminology and Criminal Justice (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
Cancer is a disease that occurs in many and perhaps all multicellular organisms. Current research is looking at how different life history characteristics among species could influence cancer rates. Because somatic maintenance is an important component of a species' life history, we hypothesize the same ecological forces shaping the life history of a species should also determine its cancer susceptibility. By looking at varying life histories, potential evolutionary trends could be used to explain differing cancer rates. Life history theory could be an important framework for understanding cancer vulnerabilities with different trade-offs between life history traits and cancer defenses. Birds have diverse life history strategies that could explain differences in cancer suppression. Peto's paradox is the observation that cancer rates do not typically increase with body size and longevity despite an increased number of cell divisions over the animal's lifetime that ought to be carcinogenic. Here we show how Peto’s paradox is negatively correlated for cancer within the clade, Aves. That is, larger, long-lived birds get more cancer than smaller, short-lived birds (p=0.0001; r2= 0.024). Sexual dimorphism in both plumage color and size differ among Aves species. We hypothesized that this could lead to a difference in cancer rates due to the amount of time and energy sexual dimorphism takes away from somatic maintenance. We tested for an association between a variety of life history traits and cancer, including reproductive potential, growth rate, incubation, mating systems, and sexual dimorphism in both color and size. We found male birds get less cancer than female birds (9.8% vs. 11.1%, p=0.0058).
ContributorsDolan, Jordyn Nicole (Author) / Maley, Carlo (Thesis director) / Harris, Valerie (Committee member) / Boddy, Amy (Committee member) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The United States has become home to the largest incarcerated population in the world, containing 25% of the world's prisoners (NAACP, 2013). Within this population, young men of color appear to be severely overrepresented. This phenomenon can be better understood with the aid of a multi-disciplinary approach within the social sciences. Evolutionary theory is combined with multiple psychological and sociological perspectives, in order to more deeply understand the multi-level intersection of prejudice and discrimination against society's disadvantaged or vulnerable populations. A synthesis of the multiple theoretical angles of social dominance theory, affordance management, and life history theory is used to suggest a threat-based, attributional framework for understanding punitive decision-making and policy support. This conceptualization also considers the importance of the legal system in effecting social change. Future research within the legal arena is recommended to enable a more refined understanding of punitive ideology and implicit bias within the criminal justice system.
ContributorsLeiferman, Lindsay M (Author) / Szeli, Ãâ°va (Thesis director) / Gómez, Alan (Committee member) / Neuberg, Steven (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor) / Department of Psychology (Contributor)
Created2014-05
Description
The purpose of this project was to evaluate possible adjudicative causes of wrongful convictions, which were strictly defined as cases where a defendant is convicted for a crime in which they are factually innocent. Most of the existing research on the causes of wrongful convictions suggests that errors occur during the investigative process. However, there is little to no research on how the court system, whose purpose is to catch and correct these mistakes prior to sentencing, fails to do just that. As such, a few possible adjudicative causes were proposed based on existing literature: errors in expert witness testimony, prosecutorial misconduct, representation by the defense, and race. Interview questions were generated based on each of these topics. Four attorneys \u2014 two prosecutors, one public defender, and one private defense attorney \u2014 were interviewed with these questions in order to qualitatively evaluate the legitimacy and the accuracy of these proposed adjudicative causes. The results indicated that attorneys rely on (and believe that jurors rely heavily on) an expert witness' performance rather than their statements and that race does not play a role in the likelihood that a defendant will be wrongfully convicted. Likewise, all four attorneys indicated that both prosecutors and defense attorneys are eager to pursue justice and that no one person is to blame for a wrongful conviction. In conclusion, errors made in the adjudicative process that lead to wrongful convictions might simply be the cause of human error.
ContributorsHietala, Kira Victoria (Author) / DeCarolis, Claudine (Thesis director) / Szeli, Eva (Committee member) / Department of Psychology (Contributor) / School of Criminology and Criminal Justice (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
In an attempt to fix the problem of an abundance of individuals with mental health issues in the criminal justice system, mental health courts have begun to develop as the newest form of problem-solving court. These courts aim to keep individuals with easily treatable mental health issues out of prison and connect them with the treatment that they need. This paper is a literature review examining the development and implementation of mental health courts across the United States. The paper first explains the essential elements to a mental health court and how they function. The main claim addressed is that: through the institution of statewide standards as well as the blanket adoption and regular measurement of national performance measures in each accredited mental health court, the large-scale and longitudinal study of mental health courts will become more practical. When these types of studies become more prevalent, the most effective practices of mental health courts will be identified and innovation will follow. The paper develops this claim by explaining the state and national regulations currently in place and the importance of standardization. It then moves into the national performance measures that should then be examined by courts once state standards are in place. The paper then explains the importance of longitudinal study to the proper collection of the significant data needed to solidify the institution of successful mental health courts. By identifying the most effective practices in mental health courts and standardizing them, this system will be able to: better help the individuals involved get appropriate treatment, promote public safety, and more effectively use taxpayer money.
ContributorsSanta Cruz, Ignacio Luis (Author) / Rigoni, Adam (Thesis director) / Kingsbury, Jeffrey (Committee member) / Department of Psychology (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Teacher assessments are often used alongside parent assessments to identify behavioral problems and patterns in school-aged children. These assessments can aid in the diagnosis of disruptive behavior disorders and are used to screen children for targeted delinquency prevention programs. Although researchers have heavily studied the relationship between parent and teacher assessments, not as much research has analyzed teacher assessments alone, specifically semiannual teacher assessments. Teacher assessments are typically conducted during the fall semester, normally a couple months into the school year, or during the spring semester, normally a couple months after the winter break period. Using data from the Pittsburgh Youth Study (PYS), we aimed to determine the temporal stability and predictive utility of semiannual teacher assessments of children's behavioral problems from 2nd grade to 5th grade. Results showed that mean assessment scores increased from the fall to the spring semester across all 4 grades. We also found that teacher assessments of behavioral problems in grade school were significantly correlated with future serious violence. Although our statistical model did not identify a specific time period or semester when these assessments were most predictive, we observed a pattern where the spring semesters were more predictive for the younger grades, and the fall semesters were more predictive for the older grades. Future research could aim to understand why this pattern exists and what its implications are.
ContributorsForthun, Marisa Nicole (Author) / Pardini, Dustin (Thesis director) / Glenberg, Arthur (Committee member) / School of International Letters and Cultures (Contributor) / Department of Psychology (Contributor) / School of Social Transformation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
The rate of cancer incidence is a morbid figure. Twenty years ago, 1 in 2 men and 1 in 3 women were predicted to be afflicted by cancer throughout their lifetime (Cancer Facts & Figures- 1998). In 2017, the rate remains the same ("Cancer Statistic Center"). Every year, more people are affected by cancer, which is a physiologically, psychologically, emotionally and socially devastating disease. And yet the language and metaphors we use to describe cancer focus our attention on the "fight" of the heroic individual against the brutal disease or on finding a cure. Despite this narrow rhetoric, there are many meaningful, supportive, and palliative measures designed to substantively and holistically care for cancer patients, beyond their medical treatment. Many of these interventions help the patient feel supported (and less alone in this "battle") by building robust communities. In this thesis, I argue the summer camps for children affected by cancer are meaningful interventions that offer palliative care throughout their treatment by creating support networks with peers going through similar medical procedures. Drawing on anecdotal evidence from three cancer camps and a detailed literature review of a subset of palliative interventions designed to promote well-being, this thesis proposes a new model for a summer camp that focuses on emotional processing emotional expression, positive psychology in order to improve palliative care for cancer patients.
ContributorsPearce, Spencer Taylor (Author) / Miller, April (Thesis director) / Brian, Jennifer (Committee member) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
The p53 gene functions as a tumor suppressor that inhibits proliferation, regulates apoptosis, DNA repair, and normal cell cycle arrest. Mutation of the p53 gene is linked to be prevalent in 50% of all human cancers. In this paper, we are exploring triple negative breast cancer and the effects of simvastatin on tumor growth and survival. Simvastatin is a drug that is primarily used to treat high cholesterol and heart disease. Simvastatin is unique because it is able to inhibit protein prenylation through regulation of the mevalonate pathway. This makes it a potential targeted drug for therapy against p53 mutant cancer. The mechanism behind this is hypothesized to be correlated to aberrant activation of the Ras pathway. The Ras subfamily functions to transcriptionally regulate cell growth and survival, and will therefore allow for a tumor to thrive if the pathway is continually and abnormally activated. The Ras protein has to be prenylated in order for activation of this pathway to occur, making statin drug treatment a viable option as a cancer treatment. This is because it acts as a regulator of the mevalonate pathway which is upstream of protein prenylation. It is thus vital to understand these pathways at both the gene and protein level in different p53 mutants to further understand if simvastatin is indeed a drug with anti-cancer properties and can be used to target cancers with p53 mutation. The goal of this project is to study the biochemistry behind the mutation of p53's sensitivity to statin. With this information we can create a possible signature for those who could benefit from Simvastatin drug treatment as a possible targeted treatment for p53 mutant cancers.
ContributorsGrewal, Harneet (Co-author) / Loo, Yi Jia Valerie (Co-author) / Anderson, Karen (Thesis director) / Blattman, Joseph (Committee member) / Ferdosi, Shayesteh (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12