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Description
Proprioception is the sense of body position, movement, force, and effort. Loss of proprioception can affect planning and control of limb and body movements, negatively impacting activities of daily living and quality of life. Assessments employing planar robots have shown that proprioceptive sensitivity is directionally dependent within the horizontal plane

Proprioception is the sense of body position, movement, force, and effort. Loss of proprioception can affect planning and control of limb and body movements, negatively impacting activities of daily living and quality of life. Assessments employing planar robots have shown that proprioceptive sensitivity is directionally dependent within the horizontal plane however, few studies have looked at proprioceptive sensitivity in 3d space. In addition, the extent to which proprioceptive sensitivity is modifiable by factors such as exogenous neuromodulation is unclear. To investigate proprioceptive sensitivity in 3d we developed a novel experimental paradigm employing a 7-DoF robot arm, which enables reliable testing of arm proprioception along arbitrary paths in 3d space, including vertical motion which has previously been neglected. A participant’s right arm was coupled to a trough held by the robot that stabilized the wrist and forearm, allowing for changes in configuration only at the elbow and shoulder. Sensitivity to imposed displacements of the endpoint of the arm were evaluated using a “same/different” task, where participant’s hands were moved 1-4 cm from a previously visited reference position. A measure of sensitivity (d’) was compared across 6 movement directions and between 2 postures. For all directions, sensitivity increased monotonically as the distance from the reference location increased. Sensitivity was also shown to be anisotropic (directionally dependent) which has implications for our understanding of the planning and control of reaching movements in 3d space.

The effect of neuromodulation on proprioceptive sensitivity was assessed using transcutaneous electrical nerve stimulation (TENS), which has been shown to have beneficial effects on human cognitive and sensorimotor performance in other contexts. In this pilot study the effects of two frequencies (30hz and 300hz) and three electrode configurations were examined. No effect of electrode configuration was found, however sensitivity with 30hz stimulation was significantly lower than with 300hz stimulation (which was similar to sensitivity without stimulation). Although TENS was shown to modulate proprioceptive sensitivity, additional experiments are required to determine if TENS can produce enhancement rather than depression of sensitivity which would have positive implications for rehabilitation of proprioceptive deficits arising from stroke and other disorders.
ContributorsKlein, Joshua (Author) / Buneo, Christopher (Thesis advisor) / Helms-Tillery, Stephen (Committee member) / Kleim, Jeffrey (Committee member) / Santello, Marco (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Previously accomplished research examined sensory integration between upper limb proprioception and tactile sensation. The active proprioceptive-tactile relationship points towards an opportunity to examine neuromodulation effects on sensory integration with respect to proprioceptive error magnitude and direction. Efforts to improve focus and attention during upper limb proprioceptive tasks results in a

Previously accomplished research examined sensory integration between upper limb proprioception and tactile sensation. The active proprioceptive-tactile relationship points towards an opportunity to examine neuromodulation effects on sensory integration with respect to proprioceptive error magnitude and direction. Efforts to improve focus and attention during upper limb proprioceptive tasks results in a decrease of proprioceptive error magnitudes and greater endpoint accuracy. Increased focus and attention can also be correlated to neurophysiological activity in the Locus Coeruleus (LC) during a variety of mental tasks. Through non-invasive trigeminal nerve stimulation, it may be possible to affect the activity of the LC and induce improvements in arousal and attention that would assist in proprioceptive estimation. The trigeminal nerve projects to the LC through the mesencephalic nucleus of the trigeminal complex, providing a pathway similar to the effects seen from vagus nerve stimulation. In this experiment, the effect of trigeminal nerve stimulation (TNS) on proprioceptive ability is evaluated by the proprioceptive estimation error magnitude and direction, while LC activation via autonomic pathways is indirectly measured using pupil diameter, pupil recovery time, and pupil velocity. TNS decreases proprioceptive error magnitude in 59% of subjects, while having no measurable impact on proprioceptive strategy. Autonomic nervous system changes were observed in 88% of subjects, with mostly parasympathetic activation and a mixed sympathetic effect.
ContributorsOrthlieb, Gerrit Chi Luk (Author) / Helms-Tillery, Stephen (Thesis advisor) / Tanner, Justin (Committee member) / Buneo, Christopher (Committee member) / Arizona State University (Publisher)
Created2019
Description

The ASU School of Dance presents New Dance Works 1, October 11 - 14, with works by dance MFA candidates Christina Harrison, Nicole Manus, and Emily Wright, performed at the Dance Studio Theatre.

ContributorsHerberger Institute School of Dance (Publisher) / Ammerman, Mark C. (Lighting designer, Set designer) / Babcock, Jacqueline (Costume designer) / Basting, Samantha (Designer) / Bauer, Lindsey (Dancer) / Downes, Erica (Dancer) / Franco, Amanda (Dancer) / Harrison, Christina (Choreographer, Dancer, Set designer, Lighting designer) / Helms-Tillery, Stephen (Musician) / Howe, Martha E. (Dancer) / Kaplan, Robert (Sound designer) / Kelley, Jean (Dancer) / Kerr, Beverly (Dancer) / Koch, Carolyn (Lighting designer) / Malan-McDonald, Sarah Jean (Dancer) / Manus, Nicole (Choreographer, Dancer) / Mihaleva, Galina (Costume designer) / Mumford, Jessica (Dancer) / Parish, Sara (Costume designer) / Richman, Jordan (Musician) / Ross, Janie D. (Dancer) / Schupp, Karen (Choreographer) / Tovoson, Kristin (Dancer) / Trujillo, David (Dancer) / Vessey, Julia A. (Dancer) / Wooldridge, Holly (Dancer) / Wright, Emily (Choreographer, Dancer, Videographer) / Yanez, Avery (Dancer)
Created2007
Description

The ASU School of Dance presents New Danceworks II, March 29-April 1, with works by dance MFA candidates Lindsey Bauer, Sara Parish, and Kristen DeBottis, performed at Dance Studio Theatre, PEBE 132.

ContributorsAmmerman, Mark C. (Lighting designer) / Basting, Samantha (Dancer) / Bauer, Lindsey (Choreographer, Dancer) / Benard, Jacqueline (Costume designer) / Boyette, Corey (Dancer) / Braun, C-c (Dancer) / Cook, Zachary (Dancer) / Debottis, Kristen (Dancer, Choreographer) / Doherty, Kelley (Dancer) / Dostal, Michael (Lighting designer) / Escoto, Evan (Dancer) / Evans, Laura (Dancer) / Grant, Blake (Dancer) / Hallinan, Jayne (Dancer) / Hauk, Chelsey (Dancer) / Keuter, Cliff (Choreographer, Set designer, Costume designer) / Khoutakoun, Alan (Dancer) / King, Natalie (Choreographer, Costume designer, Lighting designer, Set designer) / Koch, Carolyn (Lighting designer) / Lee, Chris (Lighting designer) / Love, Stormy (Dancer) / Manus, Nicole (Dancer) / Mayer, Alicia (Dancer) / McGloin, Aaron (Dancer) / McNamara, Caitlyn (Dancer) / Mesman, Travis (Dancer) / Mihaleva, Galina (Costume designer) / Parish, Sara (Choreographer, Costume designer, Dancer) / Pärt, Arvo (Composer) / Price, Meghan (Dancer) / Rajko, Stjepan (Dancer) / Ross, Janie D. (Dancer) / Spenceley, Jenni (Dancer) / Taylor, Samuel (Dancer) / Urquhart, Craig (Composer) / Vessey, Julia (Dancer, Costume designer) / Wacker, David (Dancer) / Williams, Celia (Dancer) / Wooldridge, Holly (Dancer) / Wright, Emily (Dancer)
Created2007