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Description
One of the long-standing issues that has arisen in the sports medicine field is identifying the ideal methodology to optimize recovery following anterior cruciate ligament reconstruction (ACLR). The perioperative period for ACLR is notoriously heterogeneous in nature as it consists of many variables that can impact surgical outcomes. While there

One of the long-standing issues that has arisen in the sports medicine field is identifying the ideal methodology to optimize recovery following anterior cruciate ligament reconstruction (ACLR). The perioperative period for ACLR is notoriously heterogeneous in nature as it consists of many variables that can impact surgical outcomes. While there has been extensive literature published regarding the efficacy of various recovery and rehabilitation topics, it has been widely acknowledged that certain modalities within the field of ACLR rehabilitation need further high-quality evidence to support their use in clinical practice, such as blood flow restriction (BFR) training. BFR training involves the application of a tourniquet-like cuff to the proximal aspect of a limb prior to exercise; the cuff is inflated so that it occludes venous flow but allows arterial inflow. BFR is usually combined with low-intensity (LI) resistance training, with resistance as low as 20% of one-repetition maximum (1RM). LI-BFR has been used as an emerging clinical modality to combat postoperative atrophy of the quadriceps muscles for those who have undergone ACLR, as these individuals cannot safely tolerate high muscular tension exercise after surgery. Impairments of the quadriceps are the major cause of poor functional status of patients following an otherwise successful ACLR procedure; however, these impairments can be mitigated with preoperative rehabilitation done before surgery. It was hypothesized that the use of a preoperative LI-BFR training protocol could help improve postoperative outcomes following ACLR; primarily, strength and hypertrophy of the quadriceps. When compared with a SHAM control group, subjects who were randomized to a BFR intervention group made greater preoperative strength gains in the quadriceps and recovered quadriceps mass at an earlier timepoint than that of the SHAM group aftersurgery; however, the gains made in strength were not able to be maintained in the 8-week postoperative period. While these results do not support the use of LI-BFR from the short-term perspective after ACLR, follow-up data will be used to investigate trends in re-injury and return to sport rates to evaluate the efficacy of the use of LI-BFR from a long-term perspective.
ContributorsGlattke, Kaycee Elizabeth (Author) / Lockhart, Thurmon (Thesis advisor) / McDaniel, Troy (Committee member) / Banks, Scott (Committee member) / Peterson, Daniel (Committee member) / Lee, Hyunglae (Committee member) / Arizona State University (Publisher)
Created2022
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Description
The Soft Robotic Hip Exosuit (SR-HExo) was designed, fabricated, and tested in treadmill walking experiments with healthy participants to gauge effectivity of the suit in assisting locomotion and in expanding the basin of entrainment as a method of rehabilitation. The SR-HExo consists of modular, compliant materials to move freely with

The Soft Robotic Hip Exosuit (SR-HExo) was designed, fabricated, and tested in treadmill walking experiments with healthy participants to gauge effectivity of the suit in assisting locomotion and in expanding the basin of entrainment as a method of rehabilitation. The SR-HExo consists of modular, compliant materials to move freely with a user’s range of motion and is actuated with X-oriented flat fabric pneumatic artificial muscles (X-ff-PAM) that contract when pressurized and can generate 190N of force at 200kPa in a 0.3 sec window. For use in gait assistance experiments, X-ff-PAM actuators were placed anterior and posterior to the right hip joint. Extension assistance and flexion assistance was provided in 10-45% and 50-90% of the gait cycle, respectively. Device effectivity was determined through range of motion (ROM) preservation and hip flexor and extensor muscular activity reduction. While the active suit reduced average hip ROM by 4o from the target 30o, all monitored muscles experienced significant reductions in electrical activity. The gluteus maximus and biceps femoris experienced electrical activity reduction of 13.1% and 6.6% respectively and the iliacus and rectus femoris experienced 10.7% and 27.7% respectively. To test suit rehabilitative potential, the actuators were programmed to apply periodic torque perturbations to induce locomotor entrainment. An X-ff-PAM was contracted at the subject’s preferred gait frequency and, in randomly ordered increments of 3%, increased up to 15% beyond. Perturbations located anterior and posterior to the hip were tested separately to assess impact of location on entrainment characteristics. All 11 healthy participants achieved entrainment in all 12 experimental conditions in both suit orientations. Phase-locking consistently occurred around toe-off phase of the gait cycle (GC). Extension perturbations synchronized earlier in the gait cycle (before 60% GC where peak hip extension occurs) than flexion perturbations (just after 60% GC at the transition from full hip extension to hip flexion), across group averaged results. The study demonstrated the suit can significantly extend the basin of entrainment and improve transient response compared to previously reported results and confirms that a single stable attractor exists during gait entrainment to unidirectional hip perturbations.
ContributorsBaye-Wallace, Lily (Author) / Lee, Hyunglae (Thesis advisor) / Marvi, Hamidreza (Committee member) / Berman, Spring (Committee member) / Arizona State University (Publisher)
Created2021
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Description
The world population is aging. Age-related disorders such as stroke and spinal cord injury are increasing rapidly, and such patients often suffer from mobility impairment. Wearable robotic exoskeletons are developed that serve as rehabilitation devices for these patients. In this thesis, a knee exoskeleton design with higher torque output compared

The world population is aging. Age-related disorders such as stroke and spinal cord injury are increasing rapidly, and such patients often suffer from mobility impairment. Wearable robotic exoskeletons are developed that serve as rehabilitation devices for these patients. In this thesis, a knee exoskeleton design with higher torque output compared to the first version, is designed and fabricated.

A series elastic actuator is one of the many actuation mechanisms employed in exoskeletons. In this mechanism a torsion spring is used between the actuator and human joint. It serves as torque sensor and energy buffer, making it compact and

safe.

A version of knee exoskeleton was developed using the SEA mechanism. It uses worm gear and spur gear combination to amplify the assistive torque generated from the DC motor. It weighs 1.57 kg and provides a maximum assistive torque of 11.26 N·m. It can be used as a rehabilitation device for patients affected with knee joint impairment.

A new version of exoskeleton design is proposed as an improvement over the first version. It consists of components such as brushless DC motor and planetary gear that are selected to meet the design requirements and biomechanical considerations. All the other components such as bevel gear and torsion spring are selected to be compatible with the exoskeleton. The frame of the exoskeleton is modeled in SolidWorks to be modular and easy to assemble. It is fabricated using sheet metal aluminum. It is designed to provide a maximum assistive torque of 23 N·m, two times over the present exoskeleton. A simple brace is 3D printed, making it easy to wear and use. It weighs 2.4 kg.

The exoskeleton is equipped with encoders that are used to measure spring deflection and motor angle. They act as sensors for precise control of the exoskeleton.

An impedance-based control is implemented using NI MyRIO, a FPGA based controller. The motor is controlled using a motor driver and powered using an external battery source. The bench tests and walking tests are presented. The new version of exoskeleton is compared with first version and state of the art devices.
ContributorsJhawar, Vaibhav (Author) / Zhang, Wenlong (Thesis advisor) / Sugar, Thomas G. (Committee member) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Arizona State University (Publisher)
Created2018
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Description
Human walking has been a highly studied topic in research communities because of its extreme importance to human functionality and mobility. A complex system of interconnected gait mechanisms in humans is responsible for generating robust and consistent walking motion over unpredictable ground and through challenging obstacles. One interesting aspect of

Human walking has been a highly studied topic in research communities because of its extreme importance to human functionality and mobility. A complex system of interconnected gait mechanisms in humans is responsible for generating robust and consistent walking motion over unpredictable ground and through challenging obstacles. One interesting aspect of human gait is the ability to adjust in order to accommodate varying surface grades. Typical approaches to investigating this gait function focus on incline and decline surface angles, but most experiments fail to address the effects of surface grades that cause ankle inversion and eversion. There have been several studies of ankle angle perturbation over wider ranges of grade orientations in static conditions; however, these studies do not account for effects during the gait cycle. Furthermore, contemporary studies on this topic neglect critical sources of unnatural stimulus in the design of investigative technology. It is hypothesized that the investigation of ankle angle perturbations in the frontal plane, particularly in the context of inter-leg coordination mechanisms, results in a more complete characterization of the effects of surface grade on human gait mechanisms. This greater understanding could potentially lead to significant applications in gait rehabilitation, especially for individuals who suffer from impairment as a result of stroke. A wearable pneumatic device was designed to impose inversion and eversion perturbations on the ankle through simulated surface grade changes. This prototype device was fabricated, characterized, and tested in order to assess its effectiveness. After testing and characterizing this device, it was used in a series of experiments on human subjects while data was gathered on muscular activation and gait kinematics. The results of the characterization show success in imposing inversion and eversion angle perturbations of approximately 9° with a response time of 0.5 s. Preliminary experiments focusing on inter-leg coordination with healthy human subjects show that one-sided inversion and eversion perturbations have virtually no effect on gait kinematics. However, changes in muscular activation from one-sided perturbations show statistical significance in key lower limb muscles. Thus, the prototype device demonstrates novelty in the context of human gait research for potential applications in rehabilitation.
ContributorsBarkan, Andrew (Author) / Artemiadis, Panagiotis (Thesis advisor) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Arizona State University (Publisher)
Created2016
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Description
A robotic swarm can be defined as a large group of inexpensive, interchangeable

robots with limited sensing and/or actuating capabilities that cooperate (explicitly

or implicitly) based on local communications and sensing in order to complete a

mission. Its inherent redundancy provides flexibility and robustness to failures and

environmental disturbances which guarantee the proper completion

A robotic swarm can be defined as a large group of inexpensive, interchangeable

robots with limited sensing and/or actuating capabilities that cooperate (explicitly

or implicitly) based on local communications and sensing in order to complete a

mission. Its inherent redundancy provides flexibility and robustness to failures and

environmental disturbances which guarantee the proper completion of the required

task. At the same time, human intuition and cognition can prove very useful in

extreme situations where a fast and reliable solution is needed. This idea led to the

creation of the field of Human-Swarm Interfaces (HSI) which attempts to incorporate

the human element into the control of robotic swarms for increased robustness and

reliability. The aim of the present work is to extend the current state-of-the-art in HSI

by applying ideas and principles from the field of Brain-Computer Interfaces (BCI),

which has proven to be very useful for people with motor disabilities. At first, a

preliminary investigation about the connection of brain activity and the observation

of swarm collective behaviors is conducted. After showing that such a connection

may exist, a hybrid BCI system is presented for the control of a swarm of quadrotors.

The system is based on the combination of motor imagery and the input from a game

controller, while its feasibility is proven through an extensive experimental process.

Finally, speech imagery is proposed as an alternative mental task for BCI applications.

This is done through a series of rigorous experiments and appropriate data analysis.

This work suggests that the integration of BCI principles in HSI applications can be

successful and it can potentially lead to systems that are more intuitive for the users

than the current state-of-the-art. At the same time, it motivates further research in

the area and sets the stepping stones for the potential development of the field of

Brain-Swarm Interfaces (BSI).
ContributorsKaravas, Georgios Konstantinos (Author) / Artemiadis, Panagiotis (Thesis advisor) / Berman, Spring M. (Committee member) / Lee, Hyunglae (Committee member) / Arizona State University (Publisher)
Created2017
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Description
The human ankle is a vital joint in the lower limb of the human body. As the point of interaction between the human neuromuscular system and the physical world, the ankle plays important role in lower extremity functions including postural balance and locomotion . Accurate characterization of ankle mechanics in

The human ankle is a vital joint in the lower limb of the human body. As the point of interaction between the human neuromuscular system and the physical world, the ankle plays important role in lower extremity functions including postural balance and locomotion . Accurate characterization of ankle mechanics in lower extremity function is essential not just to advance the design and control of robots physically interacting with the human lower extremities but also in rehabilitation of humans suffering from neurodegenerative disorders.

In order to characterize the ankle mechanics and understand the underlying mechanisms that influence the neuromuscular properties of the ankle, a novel multi-axial robotic platform was developed. The robotic platform is capable of simulating various haptic environments and transiently perturbing the ankle to analyze the neuromechanics of the ankle, specifically the ankle impedance. Humans modulate ankle impedance to perform various tasks of the lower limb. The robotic platform is used to analyze the modulation of ankle impedance during postural balance and locomotion on various haptic environments. Further, various factors that influence modulation of ankle impedance were identified. Using the factors identified during environment dependent impedance modulation studies, the quantitative relationship between these factors, namely the muscle activation of major ankle muscles, the weight loading on ankle and the torque generation at the ankle was analyzed during postural balance and locomotion. A universal neuromuscular model of the ankle that quantitatively relates ankle stiffness, the major component of ankle impedance, to these factors was developed.

This neuromuscular model is then used as a basis to study the alterations caused in ankle behavior due to neurodegenerative disorders such as Multiple Sclerosis and Stroke. Pilot studies to validate the analysis of altered ankle behavior and demonstrate the effectiveness of robotic rehabilitation protocols in addressing the altered ankle behavior were performed. The pilot studies demonstrate that the altered ankle mechanics can be quantified in the affected populations and correlate with the observed adverse effects of the disability. Further, robotic rehabilitation protocols improve ankle control in affected populations as seen through functional improvements in postural balance and locomotion, validating the neuromuscular approach for rehabilitation.
ContributorsNalam, Varun (Author) / Lee, Hyunglae (Thesis advisor) / Artemiadis, Panagiotis (Committee member) / Santello, Marco (Committee member) / Sugar, Thomas (Committee member) / Lockhart, Thurmon (Committee member) / Arizona State University (Publisher)
Created2020
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Description
Current exosuit technologies utilizing soft inflatable actuators for gait assistance have drawbacks of having slow dynamics and limited portability. The first part of this thesis focuses on addressing the aforementioned issues by using inflatable actuator composites (IAC) and a portable pneumatic source. Design, fabrication and finite element modeling of the

Current exosuit technologies utilizing soft inflatable actuators for gait assistance have drawbacks of having slow dynamics and limited portability. The first part of this thesis focuses on addressing the aforementioned issues by using inflatable actuator composites (IAC) and a portable pneumatic source. Design, fabrication and finite element modeling of the IAC are presented. Volume optimization of the IAC is done by varying its internal volume using finite element methods. A portable air source for use in pneumatically actuated wearable devices is also presented. Evaluation of the system is carried out by analyzing its maximum pressure and flow output. Electro-pneumatic setup, design and fabrication of the developed air source are also shown. To provide assistance to the user using the exosuit in appropriate gait phases, a gait detection system is needed. In the second part of this thesis, a gait sensing system utilizing soft fabric based inflatable sensors embedded in a silicone based shoe insole is developed. Design, fabrication and mechanical characterization of the soft gait detection sensors are given. In addition, integration of the sensors, each capable of measuring loads of 700N in a silicone based shoe insole is also shown along with its possible application in detection of various gait phases. Finally, a possible integration of the actuators, air source and gait detection shoes in making of a portable soft exosuit for knee assistance is given.
Contributorspoddar, souvik (Author) / Zhang, Wenlong (Thesis advisor) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Arizona State University (Publisher)
Created2020
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Description
The human shoulder plays an integral role in upper limb motor function. As the basis of arm motion, its performance is vital to the accomplishment of daily tasks. Impaired motor control, as a result of stroke or other disease, can cause errors in shoulder position to accumulate and propagate to

The human shoulder plays an integral role in upper limb motor function. As the basis of arm motion, its performance is vital to the accomplishment of daily tasks. Impaired motor control, as a result of stroke or other disease, can cause errors in shoulder position to accumulate and propagate to the entire arm. This is why it is a highlight of concern for clinicians and why it is an important point of study. One of the primary causes of impaired shoulder motor control is abnormal mechanical joint impedance, which can be modeled as a 2nd order system consisting of mass, spring and damper. Quantifying shoulder stiffness and damping between healthy and impaired subjects could help improve our collective understanding of how many different neuromuscular diseases impact arm performance. This improved understanding could even lead to better rehabilitation protocols for conditions such as stroke through better identification and targeting of damping dependent spasticity and stiffness dependent hypertonicity. Despite its importance, there is a fundamental knowledge gap in the understanding of shoulder impedance, mainly due to a lack of appropriate characterization tools. Therefore, in order to better quantify shoulder stiffness and damping, a novel low-inertia shoulder exoskeleton is introduced in this work. The device was developed using a newly pioneered parallel actuated robot architecture specifically designed to interface with complex biological joints like the shoulder, hip, wrist and ankle. In addition to presenting the kinematics and dynamics of the shoulder exoskeleton, a series of validation experiments are performed on a human shoulder mock-up to quantify its ability to estimate known impedance properties. Finally, some preliminary data from human experiments is provided to demonstrate the device’s ability to collect the measurements needed to estimate shoulder stiffness and damping while worn by a subject.
ContributorsHunt, Justin (Author) / Lee, Hyunglae (Thesis advisor) / Artemiadis, Panagiotis (Committee member) / Sugar, Thomas (Committee member) / Yong, Sze Zheng (Committee member) / Marvi, Hamid (Committee member) / Arizona State University (Publisher)
Created2020