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Background: Noninvasive MRI methods that can accurately detect subtle brain changes are highly desirable when studying disease-modifying interventions. Texture analysis is a novel imaging technique which utilizes the extraction of a large number of image features with high specificity and predictive power. In this investigation, we use texture analysis to

Background: Noninvasive MRI methods that can accurately detect subtle brain changes are highly desirable when studying disease-modifying interventions. Texture analysis is a novel imaging technique which utilizes the extraction of a large number of image features with high specificity and predictive power. In this investigation, we use texture analysis to assess and classify age-related changes in the right and left hippocampal regions, the areas known to show some of the earliest change in Alzheimer's disease (AD). Apolipoprotein E (APOE)'s e4 allele confers an increased risk for AD, so studying differences in APOE e4 carriers may help to ascertain subtle brain changes before there has been an obvious change in behavior. We examined texture analysis measures that predict age-related changes, which reflect atrophy in a group of cognitively normal individuals. We hypothesized that the APOE e4 carriers would exhibit significant age-related differences in texture features compared to non-carriers, so that the predictive texture features hold promise for early assessment of AD. Methods: 120 normal adults between the ages of 32 and 90 were recruited for this neuroimaging study from a larger parent study at Mayo Clinic Arizona studying longitudinal cognitive functioning (Caselli et al., 2009). As part of the parent study, the participants were genotyped for APOE genetic polymorphisms and received comprehensive cognitive testing every two years, on average. Neuroimaging was done at Barrow Neurological Institute and a 3D T1-weighted magnetic resonance image was obtained during scanning that allowed for subsequent texture analysis processing. Voxel-based features of the appearance, structure, and arrangement of these regions of interest were extracted utilizing the Mayo Clinic Python Texture Analysis Pipeline (pyTAP). Algorithms applied in feature extraction included Grey-Level Co-Occurrence Matrix (GLCM), Gabor Filter Banks (GFB), Local Binary Patterns (LBP), Discrete Orthogonal Stockwell Transform (DOST), and Laplacian-of-Gaussian Histograms (LoGH). Principal component (PC) analysis was used to reduce the dimensionality of the algorithmically selected features to 13 PCs. A stepwise forward regression model was used to determine the effect of APOE status (APOE e4 carriers vs. noncarriers), and the texture feature principal components on age (as a continuous variable). After identification of 5 significant predictors of age in the model, the individual feature coefficients of those principal components were examined to determine which features contributed most significantly to the prediction of an aging brain. Results: 70 texture features were extracted for the two regions of interest in each participant's scan. The texture features were coded as 70 initial components andwere rotated to generate 13 principal components (PC) that contributed 75% of the variance in the dataset by scree plot analysis. The forward stepwise regression model used in this exploratory study significantly predicted age, accounting for approximately 40% of the variance in the data. The regression model revealed 5 significant regressors (2 right PC's, APOE status, and 2 left PC by APOE interactions). Finally, the specific texture features that contributed to each significant PCs were identified. Conclusion: Analysis of image texture features resulted in a statistical model that was able to detect subtle changes in brain integrity associated with age in a group of participants who are cognitively normal, but have an increased risk of developing AD based on the presence of the APOE e4 phenotype. This is an important finding, given that detecting subtle changes in regions vulnerable to the effects of AD in patients could allow certain texture features to serve as noninvasive, sensitive biomarkers predictive of AD. Even with only a small number of patients, the ability for us to determine sensitive imaging biomarkers could facilitate great improvement in speed of detection and effectiveness of AD interventions..
ContributorsSilva, Annelise Michelle (Author) / Baxter, Leslie (Thesis director) / McBeath, Michael (Committee member) / Presson, Clark (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
A growing number of jobs in the US require a college degree or technical education, and the wage difference between jobs requiring a high school diploma and a college education has increased to over $17,000 per year. Enrollment levels in postsecondary education have been rising for at least the past

A growing number of jobs in the US require a college degree or technical education, and the wage difference between jobs requiring a high school diploma and a college education has increased to over $17,000 per year. Enrollment levels in postsecondary education have been rising for at least the past decade, and this paper attempts to tease out how much of the increasing enrollment is due to changes in the demand by companies for workers. A Bartik Instrument, which is a measure of local area labor demand, for each county in the US was constructed from 2007 to 2014, and using multivariate linear regression the effect of changing labor demand on local postsecondary education enrollment rates was examined. A small positive effect was found, but the effect size in relation to the total change in enrollment levels was diminutive. From the start to the end of the recession (2007 to 2010), Bartik Instrument calculated unemployment increased from 5.3% nationally to 8.2%. This level of labor demand contraction would lead to a 0.42% increase in enrollment between 2008 and 2011. The true enrollment increase over this period was 7.6%, so the model calculated 5.5% of the enrollment increase was based on the changes in labor demand.
ContributorsHerder, Daniel Steven (Author) / Dillon, Eleanor (Thesis director) / Schoellman, Todd (Committee member) / Economics Program in CLAS (Contributor) / Department of Psychology (Contributor) / Sandra Day O'Connor College of Law (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
The aim of this study is to examine the relationship between Assisted Cycle Therapy, leisure time activity levels, fine motor control, and grip force in older adults with Down syndrome (DS), all of which affect activities of daily living (ADL) and therefore quality of life. This is relevant because this

The aim of this study is to examine the relationship between Assisted Cycle Therapy, leisure time activity levels, fine motor control, and grip force in older adults with Down syndrome (DS), all of which affect activities of daily living (ADL) and therefore quality of life. This is relevant because this particular group is at risk for developing early onset Alzheimer's disease (AD), which presents itself uniquely in this population. The parent or guardian of six participants with DS completed Godin's Leisure Time Exercise Questionnaire and the participants themselves completed Purdue Pegboard and grip force assessments before and after an 8-week exercise intervention. The results were inconsistent with past research, with no change being seen in fine motor control or grip force and a decrease being seen in leisure activity. These findings are indicative of the importance of the effect of fatigue on leisure activity as well as maintaining elevated heart rate throughout exercise interventions.
ContributorsGomez, Elizabeth Danielle (Author) / Ringenbach, Shannon (Thesis director) / Coon, David (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2015-05
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Description
Studies have shown that arts programs have a positive impact on students' abilities to achieve academic success, showcase creativity, and stay focused inside and outside of the classroom. However, as school funding drops, arts programs are often the first to be cut from school curricula. Rather than drop art completely,

Studies have shown that arts programs have a positive impact on students' abilities to achieve academic success, showcase creativity, and stay focused inside and outside of the classroom. However, as school funding drops, arts programs are often the first to be cut from school curricula. Rather than drop art completely, general education teachers have the opportunity to integrate arts instruction with other content areas in their classrooms. Traditional fraction lessons and Music-infused fraction lessons were administered to two classes of fourth-grade students. The two types of lessons were presented over two separate days in each classroom. Mathematics worksheets and attitudinal surveys were administered to each student in each classroom after each lesson to gauge their understanding of the mathematics content as well as their self-perceived understanding, enjoyment and learning related to the lessons. Students in both classes were found to achieve significantly higher mean scores on the traditional fraction lesson than the music-infused fraction lesson. Lower scores in the music-infused fraction lesson may have been due to the additional component of music for students unfamiliar with music principles. Students tended to express satisfaction for both lessons. In future studies, it would be recommended to spend additional lesson instruction time on the principles of music in order help students reach deeper understanding of the music-infused fraction lesson. Other recommendations include using colorful visuals and interactive activities to establish both fraction and music concepts.
ContributorsGerrish, Julie Kathryn (Author) / Zambo, Ronald (Thesis director) / Hutchins, Catherine (Committee member) / Division of Teacher Preparation (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
With an increase in the discussion around mental health in general, there needs to be research geared toward how educational professionals may assist a student who struggles with anxiety symptoms or disorders. This study aimed to determine how students with anxiety and anxiety disorders are impacted by teachers' responses to

With an increase in the discussion around mental health in general, there needs to be research geared toward how educational professionals may assist a student who struggles with anxiety symptoms or disorders. This study aimed to determine how students with anxiety and anxiety disorders are impacted by teachers' responses to their anxiety manifestations, both positive and negative, in terms of their school experience. This study also investigated students' suggestions for how teachers may effectively assist a student who struggles with anxiety. This study used self-reported data from students from an honors college via a survey and focus groups in order to investigate these topics. The results found that students value student-teacher relationships and communication, flexibility (accommodations), and empathy from the teacher. Results suggest it is important for teachers to get to know a student and understand his or her challenges before making judgments.
ContributorsWalsh, Sydney Justine (Author) / Oakes, Wendy (Thesis director) / Harris, Pamela (Committee member) / Division of Teacher Preparation (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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DescriptionAcoustic Ecology is an undervalued field of study of the relationship between the environment and sound. This project aims to educate people on this topic and show people the importance by immersing them in virtual reality scenes. The scenes were created using VR180 content as well as 360° spatial audio.
ContributorsNeel, Jordan Tanner (Author) / LiKamWa, Robert (Thesis director) / Feisst, Sabine (Committee member) / Arts, Media and Engineering Sch T (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
The fields of psychology and education are typically housed within separate contexts. Psychology is the scientific study of the mind, thoughts, behaviors and actions (Nordqvist, 2018). The history of psychology originated centuries ago in Europe, although some attribute the beginning of mind study as far back as Aristotle. Currently, the

The fields of psychology and education are typically housed within separate contexts. Psychology is the scientific study of the mind, thoughts, behaviors and actions (Nordqvist, 2018). The history of psychology originated centuries ago in Europe, although some attribute the beginning of mind study as far back as Aristotle. Currently, the American Psychological Association has 54 active scientific divisions, ranging from the Society of Military Psychology to Psychological Hypnosis. Education, has been studied in a variety of ways, including curriculum, instruction, and educational policy. Educational psychology is a relatively new field that examines the effects of how psychological science can be applied to learning and educational success (Parankimalil, 2014). Some of the factors that educational psychologists study include: educational reform, classroom interactions, stimuli effects on learning, student motivation, individual and collective self-beliefs, goal orientation, theory of attribution, and cognitive development. It is important to distinguish that each student has a unique approach to learning. Student relationships in classrooms can profoundly impact this learning. Moreover, student motivation stems intrinsically and is influenced by external factors. Research demonstrates the positive effects sensory stimuli, including auditory, tactile, olfactory and visual, can have on student learning as well. Intrinsic and extrinsic motivation are inseparable facets of student learning, as explained by the self-determination theory. This allows for student progression from external to internal motivation, to develop better learning methods. Educational psychology is very relevant to study today, more so in a classroom where students are actively synthesizing the information learned, to apply it to real-world situations. Future research includes studying cultural effects, technology, stereotypes and reciprocal determinism in an educational setting and providing individualized learning opportunities. This research provides a transition to a student focused change rather than the cyclical model currently driving the education system today. By studying the psychological effects in a classroom, the goal is to reduce the dropout rate and improve child and adolescent education by personalizing learning.
ContributorsGanesh, Ayoshna (Co-author) / Viswanath, Pooja (Co-author) / Lynch, Christa (Thesis director) / Mitchell, Jennifer (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
This case study analyzed the internal controls of a real estate company using the widely accepted COSO framework. Testing of the internal environment and controls was completed using the COSO framework. The major internal control problem identified in the study was a lack of ethical standards in the control environment.

This case study analyzed the internal controls of a real estate company using the widely accepted COSO framework. Testing of the internal environment and controls was completed using the COSO framework. The major internal control problem identified in the study was a lack of ethical standards in the control environment. In addition to this main problem, inadequate documentation, no separation of duties, and unqualified employees were also identified as violations of effective internal controls. The department of real estate ordered a "cease and desist" on August 8, 2013 due to illegal company activities. The company participated in illegal actions regarding: the trust account and company documentation and procedures. Material weaknesses were found in the company's internal controls; therefore the result of this study was an adverse opinion on internal controls.
ContributorsFrederick, Nicole Lorraine (Author) / Munshi, Perseus (Thesis director) / Benali, Kayla (Committee member) / Barrett, The Honors College (Contributor) / School of Accountancy (Contributor) / Department of Psychology (Contributor)
Created2013-12
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Description
This project was undertaken for the purposes of exploring the feasibility of website development for arts education information. In partnership with the Arizona Commission on the Arts, ideas for website design were collected. The original plan was to build a website that would be a "one-stop-shop" for educators to find

This project was undertaken for the purposes of exploring the feasibility of website development for arts education information. In partnership with the Arizona Commission on the Arts, ideas for website design were collected. The original plan was to build a website that would be a "one-stop-shop" for educators to find arts education resources. Some resources deemed important to include on the website were: a search engine, calendar of events, curriculum ideas, discussion forum, feedback, ticketing, and financial support available. This website would make accessing arts education information easier, thus more appealing. It is understood that art is a fundamental part of education and it needs to be integrated into the public schools system, however, due to a lack of educational funding in Arizona it is important to bring outside organizations and resources into the education system. The following paper will examine how arts education is beneficial for children in grades K-12, what resources people want available on the website, what education administrators have to say about the website, and what aspects of the website would need to be included and addressed.
ContributorsJenner, Lindsay Ann (Author) / Phillips, Rhonda (Thesis director) / Ramella, Kelly (Committee member) / Nelson, Alex (Committee member) / Barrett, The Honors College (Contributor) / School of Dance (Contributor) / School of Community Resources and Development (Contributor) / Department of Psychology (Contributor)
Created2013-05
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Description
Many studies have suggested the existence of what is called the school-to-prison pipeline, a model explaining the process by which we hinder the academic development of students of color and push them instead toward the criminal justice system. This process takes place through a series of practices called exclusionary discipline

Many studies have suggested the existence of what is called the school-to-prison pipeline, a model explaining the process by which we hinder the academic development of students of color and push them instead toward the criminal justice system. This process takes place through a series of practices called exclusionary discipline practices, and these include such things as suspensions, zero tolerance policies, and the prevalence of school resource officers that often reflect larger biases or implicit racism. These practices alienate students from the academic process, increasing dropout rates and negatively affecting student achievement. There has been a great deal of research investigating these discipline policies, but significantly less research investigating how teachers perceive these practices. This study examines the perceptions and attitudes of student teachers throughout their first experiences in the classroom. It explores their attitudes toward these policies, as well as their perceptions of discipline practices and student behavior problems. In conducting interviews with four student teachers, qualitative analysis of the resulting data shows that teachers are aware of the disadvantage that students of color face, however, they perceive some of these exclusionary discipline practices to be beneficial or neutral. Teachers understood suspensions to be detrimental to students, but saw no issues with zero tolerance policies or school resource officers. For this reason, it will be important to better educate teachers to be advocates for their students, and push for better policies at the administrative and legislative levels.
ContributorsLundy, Amy Nicole (Author) / Lopez, Vera (Thesis director) / Swadener, Elizabeth (Committee member) / School of Social Transformation (Contributor) / Department of Psychology (Contributor) / School of Criminology and Criminal Justice (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05