The following paper explores the various effects of stress on the endocrine system. Many understand that being stressed can jeopardize maintaining adequate health, but what specifically happens when humans are stressed? Why does stress affect human health? This paper delves into background information, previous research, and the depths to which stress negatively affects the body. The effects stress has on the endocrine system, specifically on the hypothalamic-pituitary-thyroid axis (HPT) and hypothalamic-pituitary-adrenal axis (HPA), is discussed, and additionally, at home de-stressing methods are researched. The study included a set of participants at Arizona State University. The method took place over the course of 2 weeks: one normal week, and the other with the implementation of a de-stressing method. The normal week involved the participants living their daily lives with the addition of a stress-measuring survey, while the second week involved implementing a de-stressing method and stress-measuring survey. The purpose of this study was to discover if there was a correlation between performing these relaxation activities and decreasing stress levels in ASU students. The results found that students reported they felt more relaxed and calm after the activities. Overall, this thesis provides information and first hand research on the effects of stress and stress-reducing activities and discusses the importance of maintaining lower stress levels throughout everyday life.

The following paper explores the various effects of stress on the endocrine system. Many understand that being stressed can jeopardize maintaining adequate health, but what specifically happens when humans are stressed? Why does stress affect human health? This paper delves into background information, previous research, and the depths to which stress negatively affects the body. The effects stress has on the endocrine system, specifically on the hypothalamic-pituitary-thyroid axis (HPT) and hypothalamic-pituitary-adrenal axis (HPA), is discussed, and additionally, at home de-stressing methods are researched. The study included a set of participants at Arizona State University. The method took place over the course of 2 weeks: one normal week, and the other with the implementation of a de-stressing method. The normal week involved the participants living their daily lives with the addition of a stress-measuring survey, while the second week involved implementing a de-stressing method and stress-measuring survey. The purpose of this study was to discover if there was a correlation between performing these relaxation activities and decreasing stress levels in ASU students. The results found that students reported they felt more relaxed and calm after the activities. Overall, this thesis provides information and first hand research on the effects of stress and stress-reducing activities and discusses the importance of maintaining lower stress levels throughout everyday life.

The goal of this research project is to create a Mathcad template file capable of statistically modelling the effects of mean and standard deviation on a microparticle batch characterized by the log normal distribution model. Such a file can be applied during manufacturing to explore tolerances and increase cost and time effectiveness. Theoretical data for the time to 60% drug release and the slope and intercept of the log-log plot were collected and subjected to statistical analysis in JMP. Since the scope of this project focuses on microparticle surface degradation drug release with no drug diffusion, the characteristic variables relating to the slope (n = diffusional release exponent) and the intercept (k = kinetic constant) do not directly apply to the distribution model within the scope of the research. However, these variables are useful for analysis when the Mathcad template is applied to other types of drug release models.

Allostatic load in students, commonly referred to as student burnout, is extremely detrimental to emotional, mental, and physical health. Recent studies are finding an uptick in allostatic load in students, as academic pressures continue to rise. In order to meet the changing needs of students, universities should address the effects of overwhelming academic stress and student burnout. My thesis aimed to provide college campuses with the tools they need to do so, particularly through the implementation of Talking Circles. Talking Circles are structured discussions aimed to address specific issues, problems, or talking points. I had the opportunity to design, create, and facilitate Talking Circles with the American Holistic Nurses Association (AHNA) Chapter at Arizona State University. The focus of these circles were designed to have specific emphasis on reducing allostatic load in ASU’s student population. Thus, the Talking Circle prompts, following the principles of positive psychology, focused on emphasizing individual strengths in regards to handling stress. Through individual participant feedback, students felt “empowered, strengthened, and safe” after participating in the Talking Circles. In addition to facilitating these psychosocial support groups, I created a digital toolkit that allows for easier accessibility and distribution of Talking Circles. This allows for not only more students at ASU to feel ‘empowered and strengthened’ but for college students across the U.S. to have the tools, resources, and access to manage stress and reduce allostatic load.

This study utilized a Convergent Mixed Methods design to identify different expressions of resilience in response to a health/familial problem. The research aimed to determine which specific expressions of resilience were significantly associated with higher levels of resilience. The findings revealed two significant effects related to social support and persistence as expressions of resilience. The High Resilience group exhibited a higher proportion of individuals mentioning persistence and social support in their coping strategies. The study concluded that social support seeking is a major coping strategy among individuals with high resilience and suggested that healthcare providers, particularly nurses, should recommend and provide resources for clients to seek social support. Furthermore, the role of persistence highlights the importance of encouraging clients to set achievable goals, develop a plan, and monitor their progress to remain motivated in resolving their difficult health-related problem.