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Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires maintaining tight metabolic control through complex behavioral and pharmaceutical regimens. Subtle cognitive impairments and stress response dysregulation may partially account for problems negotiating life changes and maintaining treatment adherence among emerging adults. The current study examined whether young adults

Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires maintaining tight metabolic control through complex behavioral and pharmaceutical regimens. Subtle cognitive impairments and stress response dysregulation may partially account for problems negotiating life changes and maintaining treatment adherence among emerging adults. The current study examined whether young adults with T1DM physiologically respond to psychological stress in a dysregulated manner compared to non-diabetic peers, and if such individuals also demonstrated greater cognitive declines following psychological stress. Participants included 23 young adults with T1DM and 52 non-diabetic controls yoked to T1DM participants based on age, gender, ethnicity, participant education, and maternal education. Participants completed a laboratory-based social stressor, pre- and post-stressor neurocognitive testing, provided fingerstick blood spots (for glucose levels) and salivary samples (for cortisol levels) at five points across the protocol, and completed psychosocial questionnaires. Related measures ANOVAs were conducted to assess differences between T1DM participants and the average of yoked controls on cortisol and cognitive outcomes. Results demonstrated that differences in cortisol reactivity were dependent on T1DM participants' use of insulin pump therapy (IPT). T1DM participants not using IPT demonstrated elevated cortisol reactivity compared to matched controls. There was no difference in cortisol reactivity between the T1DM participants on IPT and matched controls. On the Stroop task, performance patterns did not differ between participants with T1DM not on IPT and matched controls. The performance of participants with T1DM on IPT slightly improved following the stressor and matched controls slightly worsened. On the Trail Making Test, the performance of participants with T1DM was not different following the stressor whereas participants without T1DM demonstrated a decline following the stressor. Participants with and without T1DM did not differ in patterns of performance on the Rey Verbal Learning Task, Sustained Attention Allocation Task, Controlled Oral Word Association Task, or overall cortisol output across participation. The results of this study are suggestive of an exaggerated cortisol response to psychological stress in T1DM and indicate potential direct and indirect protective influences of IPT.
ContributorsMarreiro, Catherine (Author) / Luecken, Linda (Thesis advisor) / Doane, Leah (Thesis advisor) / Barrera, Manuel (Committee member) / Aiken, Leona (Committee member) / Arizona State University (Publisher)
Created2013
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The transition from high school to college is associated with considerable life strain for adolescents, including higher reported levels of daily stress and negative affect (NA), and alterations in stress physiology have been linked to poor health. The purpose of this thesis was to use an ecological momentary assessment design

The transition from high school to college is associated with considerable life strain for adolescents, including higher reported levels of daily stress and negative affect (NA), and alterations in stress physiology have been linked to poor health. The purpose of this thesis was to use an ecological momentary assessment design to study associations between momentary experiences of negative affect and cortisol levels in a sample of adolescents transitioning to college. I also examined the potential moderating effects of two potential vulnerability or protective factors, alone status and perceived social support from friends. Adolescents provided salivary samples and completed paper-and-pencil diary reports of socioemotional experiences and alone status five times per day for three consecutive weekdays, as well as completed self-report questionnaires on perceived social support from friends. Within-person increases in momentary negative affect were associated with momentary cortisol reactivity. Alone status significantly moderated this association such that the association between momentary negative affect and momentary cortisol levels was only significant when individuals were with others and not when they were alone. Perceived social support from friends did not significantly moderate the within-person associations between negative affect and momentary cortisol levels. The findings add to our understanding of physiological correlates of socioemotional experiences, as well as contexts in which these associations may be exaggerated or attenuated. The findings inform our understanding of potential pathways by which physiological reactivity to socioemotional experiences may affect the health of adolescents as well as how prevention efforts could reduce potential poor health outcomes associated with heightened stress reactivity.
ContributorsKomarnisky, Sydney-Paige Milan (Author) / Doane, Leah (Thesis director) / Knight, George (Committee member) / Luecken, Linda (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of Psychology (Contributor)
Created2014-12
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This study examined whether cortisol changes caused by examination stress are more associated with acute psychological state or physical symptoms of stress. Participants’ salivary cortisol was assayed before and after taking a final examination, and a survey was administered to assess their psychological state for depression, tension, and fatigue, as

This study examined whether cortisol changes caused by examination stress are more associated with acute psychological state or physical symptoms of stress. Participants’ salivary cortisol was assayed before and after taking a final examination, and a survey was administered to assess their psychological state for depression, tension, and fatigue, as well as the degree to which they experienced a variety of physical symptoms. Physical symptoms, tension, and depression were found to positively correlate with changes in cortisol across the examination period with depression showing the strongest correlation. No correlation was observed between fatigue and changes in cortisol during the examination period. Additionally, physical symptoms were found to positively correlate with average cortisol across the examination period while depression and fatigue were found to negatively correlate with average cortisol across the examination period. No correlation was observed between tension and average cortisol during the examination period. None of these findings were statistically significant, which suggests that no relationship exists between cortisol and acute psychological state or physical symptoms of stress; however, the study was limited by its small sample size and several potentially confounding variables, making it difficult to draw any firm conclusions.
ContributorsSchlichting, Matthew James (Author) / Nesse, Randolph (Thesis director) / Doane, Leah (Committee member) / Trumble, Benjamin (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Family influences are known predictors of adolescent health and well-being trajectories, yet little research has investigated how adolescents’ orientation to family may be associated with their physiological stress responses. Influenced by the strength-based approach to culture, this study evaluated 418 Hispanic adolescents' familism values and perceived life stress in family,

Family influences are known predictors of adolescent health and well-being trajectories, yet little research has investigated how adolescents’ orientation to family may be associated with their physiological stress responses. Influenced by the strength-based approach to culture, this study evaluated 418 Hispanic adolescents' familism values and perceived life stress in family, school, and peer domains to investigate prospective associations with hypothalamic-pituitary-adrenal axis stress responses to the Group Public Speaking Task for Adolescents (GPST-A). Prior growth-mixture modeling on this sample revealed a five-class solution of cortisol responding to the GPST-A that was used here as the dependent variable: one class showed a more pronounced pattern of reactivity, potentially indicative of hyper-responsivity to the stress task; two classes showed evidence of a low to moderate cortisol response, potentially indicative of an adaptive physiological response to the challenge; and two classes showed patterns of non-responsivity, potentially indicative of hypo-responsivity. Results demonstrate that the role of familism is nuanced in the context of stressors, potentially offering both promotive and risk-amplifying effects for the physiological stress response system. This study offered several novel findings in the relation between cultural factors, salient stressors of adolescence, and HPA activity.
ContributorsSmola, Xochitl Arlene (Author) / Gonzales, Nancy (Thesis director) / Presson, Clark (Committee member) / Doane, Leah (Committee member) / Department of Psychology (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
This project examines biophilic design principles to demonstrate the impact it can have on the well-being of college students at Arizona State University. This paper details our collaboration with Hayden Library, and design elements proposed using biophilic design for the new Prayer and Meditation room as part of the 2019

This project examines biophilic design principles to demonstrate the impact it can have on the well-being of college students at Arizona State University. This paper details our collaboration with Hayden Library, and design elements proposed using biophilic design for the new Prayer and Meditation room as part of the 2019 renovations of the library. We will explore and explain what biophilia/biophilic design is and the specific impacts it can have on humans by including a literature review of previous studies and some in-person research experiences. The literature examined includes how biophilic design has specific positive effects on humans and how we can apply this to students visiting the newly renovated Hayden Library. This project also contains data and information from a workshop (November 1, 2018) organized to gather input from professionals at Shepley Bulfinch for the design of the Prayer and Meditation room. The input from the designers is combined with the body of research on biophilic design to present
to the Hayden Library 2020 renovations team.
ContributorsMcGuire, Ryan (Co-author) / Puga, Susie (Co-author) / Bernardi, Jose (Thesis director) / Bochart, Sonja (Thesis director) / Doane, Leah (Committee member) / Harrison, Anna (Committee member) / School of Criminology and Criminal Justice (Contributor) / School of Social Work (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Research has shown that environmental stressors that occur during childhood and early adolescence are associated with multiple deficits in physiological and psychological functioning later in life. The hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a potential biological mechanism through which these phenotypic alterations occur as studies have shown a link

Research has shown that environmental stressors that occur during childhood and early adolescence are associated with multiple deficits in physiological and psychological functioning later in life. The hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a potential biological mechanism through which these phenotypic alterations occur as studies have shown a link between early life adversity and altered diurnal cortisol patterns (Goldman-Mellor, Hamer, & Steptoe, 2012; Gunnar & Quevedo, 2008). Given research has shown that diurnal cortisol levels are influenced by genetic factors (Veen et al., 2011), but that a majority of differences across subjects can be attributed to the environment (Schreiber et al., 2006), phenotypic associations were explored between the quality of the home environment and children's diurnal cortisol patterns. The first aim of this study was to determine the level of genetic and environmental contributions to different parameters of diurnal cortisol rhythm. The second aim of this study was to examine whether the quality of the home environment, particularly indicators involving parenting and the physical environment, was associated with these same diurnal cortisol measures. A diverse sample of 320 twin children were assessed at 8 years using gold standard home environment interviews and a measure of diurnal cortisol rhythm across three days with three samples taken from each twin every day. Twin intraclass correlations indicated high levels of heritability for the morning to afternoon diurnal cortisol slope as well as the afternoon to evening slope, while measures of cortisol in the afternoon, evening, and across the day showed low levels of heritability, which suggested that differences in the environment were a more influential factor. Multilevel regression analyses showed that the overall quality of the home environment was found to be significantly negatively associated with cortisol levels at bedtime and negatively associated across the morning to afternoon slope at a trend level. The physical environment and emotional climate of the home were not significantly associated with any indicators of the diurnal cortisol pattern. A unique seasonality effect was noted as cortisol measurements taken from participants during the summer were significantly increased when compared to participants throughout the rest of the year. Overall, these findings showed a unique association between the quality of the home environment and diurnal cortisol levels at bedtime and perhaps the change in cortisol levels across the morning to afternoon, as well as a possible seasonal covariate which may affect diurnal cortisol measurements and one which often goes overlooked in cortisol research.
Created2018-05
Description

The transition from high school to college (TTC) is a critical period of change, the effects of which may be exacerbated for Latino students, who often face additional minority-specific stressors, such as ethnic/racial discrimination (ERD). Research has documented links between ERD and sleep outcomes in adolescents, but less is known

The transition from high school to college (TTC) is a critical period of change, the effects of which may be exacerbated for Latino students, who often face additional minority-specific stressors, such as ethnic/racial discrimination (ERD). Research has documented links between ERD and sleep outcomes in adolescents, but less is known regarding the longitudinal impacts of ERD experiences during unique risk periods (e.g., TTC). Further, despite the central role of family in Latino adolescents’ lives, less research has explored the protective role of family factors (e.g., familism, family support) in links between ERD and Latino students’ sleep health. Thus, this study examined: 1) longitudinal associations between peer- and adult-perpetrated ERD in high school and actigraphy-measured (e.g., duration, efficiency, midpoint) and subjective sleep (e.g., problems) during the first year of college among Latino adolescents, accounting for college ERD experiences, and 2) familism and family support as potential moderators of these associations. Participants were 209 Hispanic/Latino adolescents (Mage=18.10; 64.4% female; 84.7% Mexican descent; 67.9% first-generation students) assessed at two time points (i.e., last semester of high school and second semester of college). There were no longitudinal associations between high school ERD and college sleep. However, there were concurrent associations between ERD and sleep in college. Specifically, greater college peer- and adult-perpetrated ERD were associated with less duration and lower efficiency at the same time point. Further, more college adult-based ERD was additionally linked with greater sleep problems. There were no significant moderation findings; however, the interaction between high school adult-based ERD and family support predicting college sleep problems suggested that adolescents reporting low levels of adult ERD in conjunction with higher levels of family support had the fewest sleep problems. Study findings provide additional evidence that ERD from both adults and peers is associated with reduced sleep duration and quality among Latino college students and suggest that current cultural stressors may be particularly influential on sleep during major socio-contextual shifts. These findings can inform future programs (e.g., sleep interventions) that provide support for students experiencing race-based stressors, such as ERD, to promote Latino student health and well-being.

ContributorsLi, Crystal (Author) / Doane, Leah (Thesis director) / Su, Jinni (Committee member) / Ha, Thao (Committee member) / Sasser, Jeri (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / Department of Psychology (Contributor)
Created2022-12
Description
Adverse neighborhood environments have been found to negatively influence children’s sleep and physical activity outcomes (Pabayo et al., 2014; Aguilar-Farias et al., 2020). Previous literature suggests that positive parenting and familism values may play protective roles in high-risk neighborhood contexts (Romero et al., 2020). This study utilized a strengths-based approach

Adverse neighborhood environments have been found to negatively influence children’s sleep and physical activity outcomes (Pabayo et al., 2014; Aguilar-Farias et al., 2020). Previous literature suggests that positive parenting and familism values may play protective roles in high-risk neighborhood contexts (Romero et al., 2020). This study utilized a strengths-based approach to examine relations between neighborhood opportunities and sleep and physical activity in children, and whether positive parenting and familism values buffered these associations. This study utilized a racially and socioeconomically diverse sample of 710 twin children (Mage=8.44 years, SD=.69; 51.4% female; 58.5% non-Hispanic White, 23.7% Hispanic). Children wore actigraphy watches for 7 nights (M=6.79, SD=.71) to capture sleep (duration, efficiency, midpoint, midpoint variability) and physical activity (MVPA and sedentary behaviors) parameters. Objective neighborhood opportunity was evaluated using the Child Opportunity Index 2.0 (COI; Noelke et al., 2020). Positive parenting behaviors were observed and coded in the context of a parent-child interaction task. Primary caregivers reported on their children’s sleep problems and their familism values. Results revealed that higher COI predicted earlier sleep midpoint and less midpoint variability. Interactions between COI and positive parenting were nonsignificant. Though marginal, associations between the COI and midpoint variability were most negatively related in children whose primary caregiver reported high familism values. Future research should look at children’s engagement in family activities to better understand whether children who reside in low opportunity neighborhoods and experience high familism values have to face additional competing family demands, leading to greater individual variation in sleep timing.
ContributorsGutierrez, Valeria (Author) / Doane, Leah (Thesis director) / Lemery-Chalfant, Kathryn (Committee member) / Cruz, Rick (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Criminology and Criminal Justice (Contributor)
Created2022-12
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Mexican-origin families (MO) have been more negatively impacted by the COVID-19 pandemic compared to White European-Americans. Latinx youth also reported increased concern about somatic symptoms (i.e. bodily symptoms) during the pandemic compared to non-Latinx peers. Current research on the pandemic indicates that cohesive and supportive families fare better than families

Mexican-origin families (MO) have been more negatively impacted by the COVID-19 pandemic compared to White European-Americans. Latinx youth also reported increased concern about somatic symptoms (i.e. bodily symptoms) during the pandemic compared to non-Latinx peers. Current research on the pandemic indicates that cohesive and supportive families fare better than families within high-conflict households. However, no research has directly examined parent-child conflict during the pandemic in relation to youth somatic symptoms. Previous studies considered cultural proxies as predictors of somatic symptoms in Latinx children, the specific influence of prominent cultural values like familism remains less explored. Familism, emphasizing family well-being, is considered protective for Latinx youth, but evidence suggests it may pose risks in high parent-child conflict households. Utilizing Qualtrics panel, I collected data from 301 MO parents reporting on a target child (Mage= 11.4 years, SD= 3.7; 50.2% female) between March and June 2022. Approximately 40% of parents completed the survey in Spanish. Parental familism dimensions (support, family as referent, and obligations) were assessed as well as youth somatic symptoms. Changes in parent-child conflict and changes in social and family contacts due to the pandemic were also measured. Logistic regression models revealed that greater increases in conflict significantly predicted the presence of youth somatic symptoms (OR = 0.52, 95% CI= [0.27, 1.00]. Unexpectedly, total familism did not significantly moderate the relation between change in parent-child conflict and the presence of somatic symptoms (RR = 1.16, 95% CI= [0.99, 1.36]. However, post hoc analyses revealed that parental familism support was the only dimension of familism that was directly associated with the count of child somatic symptoms (RR= 0.81, 95% Confidence Interval [CI]= 0.71, 0.93). Parental familism as a referent significantly moderated the relation between change in parent-child conflict and the count of somatic symptoms (RR= 1.19, 95% CI = [1.01, 1.41]), such that higher familism values strengthened the positive relationship of change in parent-child conflict and higher count of somatic symptoms. Findings emphasize the need for future longitudinal research, considering medical conditions, to understand how parental familism values, particularly support, may buffer against somatic symptoms for Latinx youth.
ContributorsWilson, Maria Karla (Author) / Cruz, Rick A. (Thesis advisor) / Perez, Marisol (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2024
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Stress in individuals presents in various forms and may accumulate across development to predict maladaptive physical and psychological outcomes, including greater risk for the onset of internalizing symptoms. Early life stress, daily life experiences, and the stress response of the hypothalamic-pituitary-adrenal (HPA) axis have all been examined as potential predictors

Stress in individuals presents in various forms and may accumulate across development to predict maladaptive physical and psychological outcomes, including greater risk for the onset of internalizing symptoms. Early life stress, daily life experiences, and the stress response of the hypothalamic-pituitary-adrenal (HPA) axis have all been examined as potential predictors of the development of psychopathology, but rarely have researchers attempted to understand the covariation or interaction among these stress domains using a longitudinal design when looking at the influence of stress on internalizing psychopathology. Further, most research has examined these processes in adulthood or adolescence with much less attention given to the influence of these dynamic stress pathways in childhood. Guided by the biopsychosocial model of stress, this study explored early life stress, daily life stress, diurnal cortisol (cortisol AM slope), and internalizing symptoms in a racially/ethnically and socioeconomically diverse sample of twins participating in an ongoing longitudinal study (N=970 children; Arizona Twin Project; Lemery-Chalfant et al. 2013). An additive model of stress and a stress sensitization framework model were considered as potential pathways of stress to internalizing symptoms in middle childhood. Based on a thorough review of relevant literature, it was expected that each stress indicator would individually predict internalizing symptoms. It was also predicted that early life stress would moderate the associations between diurnal cortisol and internalizing symptoms, as well as daily life stress and internalizing symptoms. Multilevel modeling analyses showed that early life stress and cortisol AM slope, but not daily life stress, predicted internalizing symptoms. Early life stress did not moderate the associations between daily life stress and internalizing symptoms or cortisol AM slope and internalizing symptoms. Results support independent additive contributions of both physiological stress processes and early life parental stressors in the development of internalizing symptoms in middle childhood. Future investigation is needed to better understand the sensitizing effects of early parental life stress during this developmental stage.
ContributorsLecarie, Emma (Author) / Doane, Leah (Thesis advisor) / Davis, Mary (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2020