Matching Items (23)
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- All Subjects: psychology
- Genre: Masters Thesis
- Creators: Mickelson, Kristin
- Creators: Sanabria, Federico
Description
Nicotine is thought to underlie the reinforcing and dependence-producing effects of tobacco-containing products. Nicotine supports self-administration in rodents, although measures of its reinforcing effects are often confounded by procedures that are used to facilitate acquisition, such as food restriction, prior reinforcement training, or response-contingent co-delivery of a naturally reinforcing light. This study examined whether rats acquire nicotine self-administration in the absence of these facilitators. A new mathematical modeling procedure was used to define the criterion for acquisition and to determine dose-dependent differences in rate and asymptote levels of intake. Rats were trained across 20 daily 2-h sessions occurring 6 days/week in chambers equipped with active and inactive levers. Each active lever press resulted in nicotine reinforcement (0, 0.015, 0.03, 0.06 mg/kg, IV) and retraction of both levers for a 20-s time out, whereas inactive lever presses had no consequences. Acquisition was defined by the best fit of a logistic function (i.e., S-shaped) versus a constant function (i.e., flat line) for reinforcers obtained across sessions using a corrected Akaike information criterion (AICc) as a model selection tool. The results showed an inverted-U shaped function for dose in relation to the percentage of animals that acquired nicotine self-administration, with 46% acquiring at 0.015 mg/kg, 73% at 0.03 mg/kg, and 58% at 0.06 mg/kg. All saline rats failed to acquire as expected. For rats that acquired nicotine self-administration, multiple model comparisons demonstrated that the asymptote (highest number of reinforcers/session) and half learning point (h; session during which half the assymptote had been achieved) were justified as free parameters of the reinforcers/session function, indicating that these parameters vary with nicotine dose. Asymptote exhibited an inverted U-shaped function across doses and half learning point exhibited a negative relationship to dose (i.e., the higher the dose the fewer sessions to reach h). These findings suggest that some rats acquire nicotine self-administration without using procedures that confound measures of acquisition rate. Furthermore, the modeling approach provides a new way of defining acquisition of drug self-administration that takes advantage of using all data generated from individual subjects and is less arbitrary than some criteria that are currently used.
ContributorsCole, Natalie (Author) / Neisewander, Janet L (Thesis advisor) / Sanabria, Federico (Thesis advisor) / Bimonte-Nelson, Heather A. (Committee member) / Olive, Michael F (Committee member) / Arizona State University (Publisher)
Created2011
Description
When a rolling ball exits a spiral tube, it typically maintains its final inertial state and travels along straight line in concordance with Newton's first law of motion. Yet, most people predict that the ball will curve, a "naive physics" misconception called the curvilinear impetus (CI) bias. In the current paper, we explore the ecological hypothesis that the CI bias arises from overgeneralization of correct motion of biological agents. Previous research has established that humans curve when exiting a spiral maze, and college students believe this motion is the same for balls and humans. The current paper consists of two follow up experiments. The first experiment tested the exiting behavior of rodents from a spiral rat maze. Though there were weaknesses in design and procedures of the maze, the findings support that rats do not behave like humans who exhibit the CI bias when exiting a spiral maze. These results are consistent with the CI bias being an overgeneralization of human motion, rather than generic biological motion. The second experiment tested physics teachers on their conception of how a humans and balls behave when exiting a spiral tube. Teachers demonstrated correct knowledge of the straight trajectory of a ball, but generalized the ball's behavior to human motion. Thus physics teachers exhibit the opposite bias from college students and presume that all motion is like inanimate motion. This evidence supports that this type of naive physics inertial bias is at least partly due to participants overgeneralizing both inanimate and animate motion to be the same, perhaps in an effort to minimize cognitive reference memory load. In short, physics training appears not to eliminate the bias, but rather to simply shift it from the presumption of stereotypical animate to stereotypical inanimate behavior.
ContributorsDye, Rosaline (Author) / Mcbeath, Michael K (Thesis advisor) / Sanabria, Federico (Committee member) / Megowan, Colleen (Committee member) / Arizona State University (Publisher)
Created2013
Description
Anxiety sensitivity (AS; the fear of anxiety-related bodily sensations) has been earmarked as a significant risk factor in the development and maintenance of pathological anxiety in adults and children. Given the potential implications of heightened AS, recent research has focused on investigating the etiology and developmental course of elevated AS; however, most of this work has been conducted with adults and is retrospective in nature. Data from college students show that early anxiety-related learning experiences may be a primary source of heightened AS levels, but it remains unclear whether AS in children is linked to their learning experiences (i.e., parental reinforcement, modeling, punishment, and/or transmission of information about anxiety-related behaviors). Based on AS theory and its iterations, an emerging theoretical model was developed to aid further exploration of the putative causes and consequences of heightened AS levels. Using a sample of 70 clinic-referred youth (ages 6 to 16 years old; 51.4% Hispanic/Latino), the present study sought to further explicate the role of learning in the development of AS and anxiety symptoms. Results suggest that childhood learning experiences may be an important precursor to heightened AS levels and, subsequently, increased experiences of anxiety symptoms. Findings also indicate that some youth may be more vulnerable to anxiety-related learning experiences and suggest that culture may play a role in the relations among learning, AS, and anxiety symptoms.
ContributorsHolly, Lindsay (Author) / Pina, Armando A (Thesis advisor) / Crnic, Keith A (Committee member) / Sanabria, Federico (Committee member) / Arizona State University (Publisher)
Created2012
Description
How early life is experienced and perceived can greatly affect mental and physical health outcomes. An individual is greatly influenced by their first models of what social relationships look and feel like, and with time also learn how to survive when less favorable social experiences occur. The lessons learned may lead to healthy problem solving and resilience, or it may lead to unhealthy problem-solving habits that hinder well-being. Anxious thoughts and other mental health symptoms may accompany an individual long-term and hinder an essential need for a healthy life. The first main purpose of this thesis is to examine the impact of Adverse Childhood Experiences (ACEs) on mental health (anxiety symptoms), and on sleep quality (an essential need). The second purpose of my thesis is to investigate the impact of genetics on resilience, specifically, the mu-opioid receptor gene. The first hypothesis proposed ACEs that were perceived as more traumatic and occurred more frequently would be associated with more poor sleep quality symptoms. The second hypothesis predicted that anxiety symptoms would mediate the association. The third hypothesis (exploratory) suggested that an individual’s alleles for the mu-opioid receptor gene would moderate the mediation pathway. The study was conducted with 318 participants between the ages of 18 and 35 years old. The study demonstrated a direct effect for ACEs and sleep. Anxiety mediated the association between ACEs (exposure and severity) and sleep (insomnia, quality, sleepiness), suggesting that ACEs possibly increase feelings of anxiety which, in turn, lead to worse sleep outcomes. Finally, the moderated-mediation model with OPRM1 as the moderator, was not significant for the mediation pathway A; however, there was a significant interaction with anxiety and sleep symptoms.
ContributorsBailey, Elise (Author) / Mickelson, Kristin (Thesis advisor) / Burleson, Mary (Committee member) / Petrov, Megan (Committee member) / Arizona State University (Publisher)
Created2022
Description
With widespread increases in the use of electronic communication technology, cyber-sexual harassment (CSH) has been on the rise. Broadly defined, CSH is unwelcome and repeated conduct of a sexual nature performed through electronic technology. The prevalence of CSH reported in previous studies varies significantly due in part to inconsistencies in how CSH is defined and measured. Whereas four existing scales measuring aspects of CSH have been published, each has several limitations. This research aims to develop and psychometrically validate the Multidimensional Cyber-Sexual Harassment Experiences and Attitudes Scale for Victimization (MCSHEA-V), which taps into five key components of CSH, including: (1) gathering sexual information online, (2) image and video-based sexual harassment, (3) offensive comments or posts, (4) coercive behaviors, and (5) CSH attitudes. In Study 1, a sample of psychology graduate students and faculty (N = 13) evaluated the content validity of the MCSHEA-V items, leading to key improvements in item relevance, clarity, and wording. In Study 2, a sample of adult participants (N = 298) completed the initial version of the scale through the online survey platform, Prolific.co. Confirmatory factor analyses indicated the proposed 5-factor structure was a good fit, but exploratory factor analyses indicated the items represented an alternative 4-factor structure. Specifically, these items captured dyadic CSH behaviors, CSH behaviors that affect one’s reputation, perceptions of the seriousness of CSH, and CSH victim-blaming behaviors. In Study 3, an additional sample of adult participants (N = 207) was surveyed via Prolific.co. Separate confirmatory factor analyses indicated the 4-factor model was the best fit. Overall, the MCSHEA-V will contribute to a clearer understanding of the defining features and prevalence of CSH victimization and facilitate future research through the introduction of a psychometrically-validated measurement tool.
ContributorsWheeler, Brittany (Author) / Hall, Deborah (Thesis advisor) / Mickelson, Kristin (Committee member) / Burleson, Mary (Committee member) / Arizona State University (Publisher)
Created2022
Description
Although adverse events cannot always be prevented, the negative outcomes on development can potentially be modified by considering methods of fostering positive emotional and behavioral responses. The study examined biopsychosocial health outcomes in the presence of uncontrollable adverse childhood events with the goal of identifying a potential intervention to increase resilience, health, and safe behaviors among at-risk children. It was hypothesized that adverse events can result in positive biopsychosocial outcomes in the presence of high scores on the Positive Emotion, Engagement, Relationships, Meaning, and Accomplishments (PERMA) model of well-being, self-efficacy, gratitude, and the ability to envision a positive future self. The study retrospectively examined adverse childhood events and present behavioral, emotional, and physical health outcomes. Participant (n = 685) data were analyzed using Hayes PROCESS (v3.5) to test all components of the moderation model. Results suggest that as adverse events increase, health adversity also increases. However, those with high intrapersonal strengths showed better health outcomes. Through understanding intrapersonal pathways in the presence of adverse events, the study can potentially identify mechanisms important for promoting resilient outcomes in childhood that could cascade into adulthood.
ContributorsBraunstein, Bailey Marie (Author) / Mickelson, Kristin (Thesis advisor) / Hall, Deborah (Committee member) / Lindstrom-Johnson, Sarah (Committee member) / Arizona State University (Publisher)
Created2022
Description
The COVID-19 pandemic has affected many aspects of daily life due to social distancing guidelines, including physical exercise. Prior research indicates that physical activity is a potent resilience factor against stress’ impact on mental health. Further, research suggests that social integration and participation positively contributes to mental well-being. Yet, one aspect of physical activity that may be particularly impacted by social distancing guidelines is the social context. It is unclear if those who participated in social physical activity prior to the COVID pandemic are more impacted by the restrictions placed on these behaviors. In a sample of 519 adults in the United States, the current longitudinal study examined whether participation in social physical activity, compared to individual physical activity, moderates the influence of pandemic stress on mental health and whether there are gender differences between men and women in these associations. Study results indicated physical activity did benefit mental health during the COVID pandemic. However, greater social physical activity did not buffer against the negative impact of stress. Future research should examine other variables potentially influencing these relationships, and examine them under non-pandemic conditions.
ContributorsKaneris, Marianna Irene (Author) / Mickelson, Kristin (Thesis advisor) / Hall, Deborah (Committee member) / Mean, Lindsey (Committee member) / Arizona State University (Publisher)
Created2022
Description
Given the prevalence and severity of dating violence (DV) in our World, uncovering the long-term effects of DV is pivotal. This thesis provides information about how prior DV impacts a survivor’s future relationships. First, understanding the association between prior DV and current relationship satisfaction. Next, suggesting potential moderators between DV and current relationship satisfaction in forms of resilience. Tangible resilience strategies such as seeking therapy and obtaining an order of protection were assessed as potential moderators. As well as one’s attachment style as a predictor of how one overcomes prior DV and impacts current relationship satisfaction. A study was conducted with 218 participants from both the United States and international countries. Prior DV was a predictor of relationship satisfaction, however in the adverse way as predicted. Survivors of prior dating violence reported higher levels of current relationship satisfaction. Tangible resilience and secure attachment style were both significant moderators of the relationship between prior DV and current relationship satisfaction. These results present new ways to face the challenge of overcoming the repercussions of DV for survivors. As well as provide hope and support to all survivors of DV that their past does not have to impact their future.
ContributorsGraham, Kaylyn (Author) / Mickelson, Kristin (Thesis advisor) / Randall, Ashley (Committee member) / Burleson, Mary (Committee member) / Arizona State University (Publisher)
Created2022
Description
The rate at which an operant is produced has often functioned as a fundamental measure of the efficacy of a reinforcer. Previous research has shown that operant behavior is typically organized into bouts implying that rate of responding is a composite of bout-initiation rate, within-bout response rate, and mean bout length. However, it is still unclear whether this organization of behavioral responses into bouts is a product of the motivational processes or a property that arises from the location of an organism in space. To test this proximity hypothesis, two-response sequences were intermittently reinforced: either pressing one lever twice (manipulandum proximal to response termination) or pressing each of two levers, located on either side of an operant chamber, once (manipulandum distal to response termination). In Experiment 1, rats were first trained to lever press for food on a VI schedule before being exposed to the alternation paradigm. Experiment 1 consisted of three phases. In Phase 1, food-deprived rats learned the alternation paradigm under a tandem variable time (VT) 150-s fixed-ratio (FR) 1 schedule of reinforcement. Phase 2 and 3 increased the FR requirement from 1 to 3 or 5 and removed food deprivation, respectively, to examine their effect on response-rate components. In Experiment 2, rats switched between trials consisting of pressing a single lever repeatedly or alternating between two levers for reward. Following stable behavior, lever pressing was extinguished in both trial types to the effect of extinction on response-rate components. Overall, behavioral bouts persisted under the alternation paradigm suggesting that they reflect motivational states and not just location. Additionally, bout-initiation rate decreased with increased response effort and decreased deprivation. Taken together, these results provide support for the use of response-bout analysis to evaluate the value of a reinforcer and its sensitivity to pharmacological manipulations.
ContributorsGildea, Matthew (Author) / Sanabria, Federico (Thesis advisor) / Gewirtz, Jonathan (Committee member) / Verpeut, Jessica (Committee member) / Arizona State University (Publisher)
Created2024
Description
With its ever-increasing prevalence throughout the world, social media use has become a primary means of communication and connection with others. Much research has been dedicated to the topic of social media use, suggesting both positive and negative outcomes for those who are online more frequently. While uploading content and interacting with posts that others have created is associated with social comparison and identity formation, there is little research to date that examines the relationship between social media use and an individual’s meaning in life. One of the greater benefits of social media use is the ease with which people can curate their own personal identities, and this has led to an increase in users—particularly young adults—posting sexualized images of themselves for social gain. Untested in prior research is the relationship between self-objectification via social media and life meaning. For my thesis, I proposed a moderation model in which participants who reported higher levels of self-objectified beliefs and online habits would also report lower levels of meaning in life. Furthermore, I hypothesized that there would be unique differences between genders and sexual orientations that would also serve as moderators, such that heterosexual women and LGBQ men would demonstrate the lowest levels of life meaning when reporting high levels of self-objectification. Results from analyses found that while there was no significant relationship between active social media use and meaning in life, there was a significant three-way interaction between objectified social media use, gender and sexual orientation, and meaning. Findings from this study provide support for previous research that has found LGBQ men and heterosexual women face the most adverse effects from self-objectification. These results suggest that self-objectified social media use can negatively impact life meaning for certain populations.
ContributorsMostoller, Alexis (Author) / Mickelson, Kristin (Thesis advisor) / Salerno, Jessica (Committee member) / Burleson, Mary (Committee member) / Arizona State University (Publisher)
Created2022