Matching Items (13)
Filtering by

Clear all filters

136445-Thumbnail Image.png
Description
Environmental and genetic factors contribute to schizophrenia etiology, yet few studies have demonstrated how environmental stimuli impact genes associated with the disorder. Immediate early genes (IEGs) are of great interest to schizophrenia research because they are activated in response to physiological stress from the environment, and subsequently regulate the expression

Environmental and genetic factors contribute to schizophrenia etiology, yet few studies have demonstrated how environmental stimuli impact genes associated with the disorder. Immediate early genes (IEGs) are of great interest to schizophrenia research because they are activated in response to physiological stress from the environment, and subsequently regulate the expression of downstream genes that are essential to neuropsychiatric function. An IEG, early growth response 3 (EGR3) has been identified as a main gene involved in a network of transcription factors implicated in schizophrenia susceptibility. The serotonin 2A receptor (5-HT2AR) seems to play an important role in schizophrenia and the dysfunction of the 5-HT2AR encoding gene, HTR2A, within the prefrontal cortex (PFC) contributes to multiple psychiatric illnesses including schizophrenia. EGR3's role as a transcription factor that is activated by environmental stimuli suggests it may regulate Htr2a transcription in response to physiological stress, thus affecting 5-HT2AR function in the prefrontal cortex (PFC). The aim of this study was to examine the relationship between Egr3 activation and Htr2a expression after an environmental stimulus. Sleep deprivation is an acute physiological stressor that activates Egr3. Therefore to examine the relationship between Egr3 and Htr2a expression after an acute stress, wild type and Egr3 knockout mice that express EGFP under the control of the Htr2a promoter were sleep deprived for 8 hours. We used immunohistochemistry to determine the location and density of Htr2a-EGFP expression after sleep deprivation and found that Htr2a-EGFP expression was not affected by sex or subregions of the PFC. Additionally, Htr2a-EGFP expression was not affected by the loss of Egr3 or sleep deprivation within the PFC. The LPFC subregions, layers V and VI showed significantly more Htr2a-EGFP expression than layers I-III in all animals for both sleep deprivation and control conditions. Possible explanations for the lack of significant effects in this study may be the limited sample size or possible biological abnormalities in the Htr2a-EGFP mice. Nonetheless, we did successfully visualize the anatomical distribution of Htr2a in the prefrontal cortex via immunohistochemical staining. This study and future studies will provide insight into how Egr3 activation affects Htr2a expression in the PFC and how physiological stress from the environment can alter candidate schizophrenia gene function.
ContributorsSabatino, Alissa Marie (Author) / Gallitano, Amelia (Thesis director) / Hruschka, Daniel (Thesis director) / Maple, Amanda (Committee member) / Barrett, The Honors College (Contributor)
Created2014-05
136710-Thumbnail Image.png
Description
Some scholars have suggested that individuals are inclined to believe that they have souls because they are also inclined to believe that they have a core, immutable self. The present study will explore this question in several parts. First, what is the extent to which individuals report having a core

Some scholars have suggested that individuals are inclined to believe that they have souls because they are also inclined to believe that they have a core, immutable self. The present study will explore this question in several parts. First, what is the extent to which individuals report having a core self? Next, how do beliefs about a core self relate to belief or non-belief in an eternal soul? The final question looks at location as an extension of the core self and soul relationship. Where is the self perceived to reside within a dualistic framework, the body or the soul? This study assessed the stated beliefs of 200 respondents using Amazon Mechanical Turk as a recruiting platform. Greater belief in a core self was moderately associated with greater belief in an eternal soul (r= 0.30, p<.01), and with belief in the self as a reflection of the soul (r=0.31, p<.01) and as a reflection of the brain (r=0.21, p<.01). This suggests that belief in a core self does hold association with belief in an eternal soul. However, its perceived location seems to show little preference as residing withing the soul versus the body.
ContributorsLy, Destiny (Author) / Hruschka, Daniel (Thesis director) / Parker, John (Contributor) / Barrett, The Honors College (Contributor)
Created2014-12
132991-Thumbnail Image.png
Description
More than 40% of all U.S. opioid overdose deaths in 2016 involved a prescription opioid, with more than 46 people dying every day from overdoses involving prescription opioids, (CDC, 2017). Over the years, lawmakers have implemented policies and laws to address the opioid epidemic, and many of these vary from

More than 40% of all U.S. opioid overdose deaths in 2016 involved a prescription opioid, with more than 46 people dying every day from overdoses involving prescription opioids, (CDC, 2017). Over the years, lawmakers have implemented policies and laws to address the opioid epidemic, and many of these vary from state to state. This study will lay out the basic guidelines of common pieces of legislation. It also examines relationships between 6 state-specific prescribing or preventative laws and associated changes in opioid-related deaths using a longitudinal cross-state study design (2007-2015). Specifically, it uses a linear regression to examine changes in state-specific rates of opioid-related deaths after implementation of specific policies, and whether states implementing these policies saw smaller increases than states without these policies. Initial key findings of this study show that three policies have a statistically significant association with opioid related overdose deaths are—Good Samaritan Laws, Standing Order Laws, and Naloxone Liability Laws. Paradoxically, all three policies correlated with an increase in opioid overdose deaths between 2007 and 2016. However, after correcting for the potential spurious relationship between state-specific timing of policy implementation and death rates, two policies have a statistically significant association (alpha <0.05) with opioid overdose death rates. First, the Naloxone Liability Laws were significantly associated with changes in opioid-related deaths and was correlated with a 0.33 log increase in opioid overdose death rates, or a 29% increase. This equates to about 1.39 more deaths per year per 100,000 people. Second, the legislation that allows for 3rd Party Naloxone prescriptions correlated with a 0.33 log decrease in opioid overdose death rates, or a 29% decrease. This equates to 1.39 fewer deaths per year per 100,000 people.
ContributorsDavis, Joshua Alan (Author) / Hruschka, Daniel (Thesis director) / Gaughan, Monica (Committee member) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
147563-Thumbnail Image.png
Description

The Beck Depression Inventory II (BDI-II) and the Patient Health Questionnaire 9 (PHQ-9) are highly valid depressive testing tools used to measure the symptom profile of depression globally and in South Asia, respectively (Steer et al., 1998; Kroenke et al, 2001). Even though the South Asian population comprises only

The Beck Depression Inventory II (BDI-II) and the Patient Health Questionnaire 9 (PHQ-9) are highly valid depressive testing tools used to measure the symptom profile of depression globally and in South Asia, respectively (Steer et al., 1998; Kroenke et al, 2001). Even though the South Asian population comprises only 23% of the world’s population, it represents one-fifth of the world’s mental health disorders (Ogbo et al., 2018). Although this population is highly affected by mental disorders, there is a lack of culturally relevant research on specific subsections of the South Asian population.<br/><br/>As such, the goal of this study is to investigate the differences in the symptom profile of depression in native and immigrant South Asian populations. We investigated the role of collective self-esteem and perceived discrimination on mental health. <br/><br/>For the purpose of this study, participants were asked a series of questions about their depressive symptoms, self-esteem and perceived discrimination using various depressive screening measures, a self-esteem scale, and a perceived discrimination scale.<br/><br/>We found that immigrants demonstrated higher depressive symptoms than Native South Asians as immigration was viewed as a stressor. First-generation and second-generation South Asian immigrants identified equally with somatic and psychological symptoms. These symptoms were positively correlated with perceived discrimination, and collective self-esteem was shown to increase the likelihood of these symptoms.<br/><br/>This being said, the results from this study may be generalized only to South Asian immigrants who come from highly educated and high-income households. Since seeking professional help and being aware of one’s mental health is vital for wellbeing, the results from this study may spark the interest in an open communication about mental health within the South Asian immigrant community as well as aid in the restructuring of a highly reliable and valid measurement to be specific to a culture.

ContributorsMurthy, Nithara (Co-author) / Swaminathan, Manasa (Co-author) / Vogel, Joanne (Thesis director) / Kwan, Sau (Committee member) / Department of Psychology (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
184520-Thumbnail Image.png
Description
Joseph Henrich coined the term WEIRD: Western, Educated, Industrialized, Rich, and Democratic to describe individuals who were noted to be the predominant sample subjects in psychology research studies and whose behavior is often used to represent behavioral studies (Henrich et al., 2010). Three distinctive conclusions were drawn from a review

Joseph Henrich coined the term WEIRD: Western, Educated, Industrialized, Rich, and Democratic to describe individuals who were noted to be the predominant sample subjects in psychology research studies and whose behavior is often used to represent behavioral studies (Henrich et al., 2010). Three distinctive conclusions were drawn from a review of a compilation of psychological and behavioral science research: massively biased samples – with approximately 96% of the experimental participants being drawn from northern Europe, North America, or Australia, and 70% of this subpopulation being American undergraduates; psychological diversity; and psychological peculiarity. In Henrich’s book, he discusses the points in history when the West began to differentiate themselves, psychologically speaking, from other cultures and the various driving factors that contributed to this change. Henrich emphasizes the narrowness of sampling within the psychological and behavioral sciences due to the nature of WEIRD societies. As such, it is difficult to generalize the normative ways of development in cross-cultural settings when there is a lack of representation for non-WEIRD societies. For example, shame is one of the vehicles that heavily influences non-WEIRD societies while guilt appears to be a driving factor in WEIRD societies. An idea that is guided by shame, “losing face,” is prominent in multiple non-WEIRD populations and may act as the driving force for adolescents to adopt ‘adult-like’ behaviors. Specifically, “migrant youth” is a phenomenon whereby youth from underdeveloped and developing nations leave some vestige of home to better themselves (Cortina et al., 2014). There is evidence to suggest that unaccompanied Latino migrant youth (LMY) in particular, live as “adults” despite being adolescents (Carlos Chavez et al., 2021). Whether their migration to the U.S. is motivated for a better life and future (Carlos Chavez et al., 2022) or as a family strategy (Stark & Stark, 1991) for the financial survival of the household, it may be possible that unaccompanied LMY are willing to sacrifice themselves in order to ‘save their parents’ face’ from poverty, hunger, and poor health. This type of ‘adult-like’ behavior among LMY challenges the normative human development literature and brings to surface the cultural implications and psychological consequences of non-WEIRD individuals who live in WEIRD societies.
ContributorsTang, Tracy (Author) / Carlos Chavez, Fiorella (Thesis director) / Zhang, Xing (Committee member) / Barrett, The Honors College (Contributor) / School of Music, Dance and Theatre (Contributor) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor) / School of Human Evolution & Social Change (Contributor)
Created2023-05
Description

The structure of this project will open with the dangers posed by inadequate screening techniques to both individuals with Body Dysmorphic Disorder and their plastic surgeons. This discussion will be followed by a summary of the existing mental health screenings implemented in plastic surgery clinics and their limitations. The assessments

The structure of this project will open with the dangers posed by inadequate screening techniques to both individuals with Body Dysmorphic Disorder and their plastic surgeons. This discussion will be followed by a summary of the existing mental health screenings implemented in plastic surgery clinics and their limitations. The assessments that will be examined include The Body Dysmorphic Disorder Examination, The Body Dysmorphic Disorder Examination - Self-Report, The Cosmetic Procedure Screening Questionnaire, The Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder, and The Body Dysmorphic Disorder Questionnaire. These screening techniques were chosen based on a multitude of factors: frequency of use in psychiatric and cosmetic settings, innovation of screening methodology, and significance of studies that utilize the assessments. After describing the screening techniques, there will be a brief discussion of the limitations of developing a screening method for Body Dysmorphic Disorder, along with suggestions for methodology in future research. This thesis will demonstrate that no existing screening method for Body Dysmorphic Disorder in aesthetic surgery is flawless. Still, future research efforts should investigate combining questionnaires and clinical interviews to screen for the disorder within clinics efficiently and more reliably.

ContributorsOsterkorn, Ian (Author) / Alcantara, Christiane (Thesis director) / Cavanaugh Toft, Carolyn (Committee member) / Barrett, The Honors College (Contributor) / School of Human Evolution & Social Change (Contributor) / Department of Psychology (Contributor) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor)
Created2023-05
189337-Thumbnail Image.png
Description
Social norms are unwritten behavioral codes. They direct individual behaviors, facilitate interpersonal coordination and cooperation, and lead to variation among human populations. Understanding how norms are maintained and how they change is critical for understanding human evolutionary psychology, social organization, and cultural change. This dissertation uses a mathematical model and

Social norms are unwritten behavioral codes. They direct individual behaviors, facilitate interpersonal coordination and cooperation, and lead to variation among human populations. Understanding how norms are maintained and how they change is critical for understanding human evolutionary psychology, social organization, and cultural change. This dissertation uses a mathematical model and a field study to answer two questions: First, what factors determine the content and dynamics of a social norm? Second, how do people make decisions in a normative context? The mathematical model finds that contrary to the popular belief that even arbitrary or deleterious social norms can be maintained once established because deviants suffer coordination failures and social sanctions, norms with continuously varying options cannot be maintained by the pressure to do what others do. Instead, continuous norms evolve to the optimum determined by environmental pressure, individual preferences, or cognitive processes. Therefore, the content of norms across human societies may be less historically constrained than previously assumed. The field study shows that unlike what rational choice theory predicts, people in a small-scale subsistence society do not calculate the ecological and social payoffs of different behaviors in a normative context, even when they have the information to do so. Instead, they rely heavily on social information about what others do. This decision-making algorithm, together with mental categorization that ignores small deviations, and cognitive biases that favor the division prescribed by the norm, maintain an ecologically inefficient and widely disliked cooperative surplus division norm in a Derung village, Dizhengdang, in Yunnan, China.
ContributorsYan, Minhua (Author) / Boyd, Robert (Thesis advisor) / Mathew, Sarah (Thesis advisor) / Hruschka, Daniel (Committee member) / Arizona State University (Publisher)
Created2023
Description
Asian Americans are facing unprecedented and growing mental health issues brought by anti-Asian Racism and other forms of hyper-visible oppression (Yellow Horse et al., 2021). In response to racism, one potential solution for bolstering mental health outcomes among Asian Americans is critical reflection. Critical reflection is the process through which

Asian Americans are facing unprecedented and growing mental health issues brought by anti-Asian Racism and other forms of hyper-visible oppression (Yellow Horse et al., 2021). In response to racism, one potential solution for bolstering mental health outcomes among Asian Americans is critical reflection. Critical reflection is the process through which oppressed and marginalized people critically analyze oppressive social conditions (e.g., racism, sexism, and more) and consider actions they can take to change them (Watts et al., 2011). Recent research suggests that, overall, there is a strong link between critical reflection and the well-being of youth of color (Maker Castro et al., 2022). However, this relationship may vary based on additional factors, such as strategies used to cope with racism-related stress. For instance, Asian Americans with lower critical reflection about racism (e.g., as evidenced by endorsement of colorblind racial ideology, or the belief that racial differences are irrelevant and racism no longer exists) had a higher tendency to use avoidant coping mechanisms to deal with discrimination (Yi et al., 2022; Lewis et al., 2019). Additionally, there is other evidence to support that Asian Americans who held more colorblind racial attitudes experienced less anxiety when challenged with ambiguous discrimination compared to Asian Americans who held less colorblind racial attitudes (Lee, 2016). Overall, the literature suggests the importance of the relationship between critical reflection and mental health. However, studies have yet to quantitatively explore the impacts of critical reflection and strategies to cope with discrimination on mental health outcomes among Asian Americans (Spanierman et al., 2021) and young adults (Maker Castro et al., 2022). The current study seeks to address this gap in the literature by examining the role of strategies to cope with discrimination in the relationship between Asian Americans’ critical reflection and mental health outcomes. It is crucial to explore these factors as Asian American students continue to shoulder prejudice, stereotypes, and systemic racism in professional and educational institutions. We hypothesize that the relationship between critical reflection and mental health will be mediated by the strategies used to cope with discrimination. More specifically, we expect that low levels of critical reflection (as indicated by high levels of color-blind racial attitudes) are related to greater use of internalization, substance use, and detachment strategies to cope with discrimination, which is related to greater endorsement of depression, anxiety, and stress symptoms. Data for this study were drawn from a larger study on college students’ experiences in ethnic studies courses. Participants were 288 Asian Americans recruited from ethnic studies courses at universities in various regions of the United States. During the first two weeks of their ethnic studies course, participants completed an online survey about their racial attitudes, critical consciousness, and psychological well-being. Mediation analyses will be conducted using the PROCESS macro (Hayes, 2022) on SPSS version 27. Critical reflection, as measured by participants’ total mean score on the Color-Blind Racial Attitudes Scale (Neville et al., 2000; Keum et al., 2018) will be included as the independent variable; subscale scores on the Coping with Discrimination Scale (Wei & Alvarez, 2010) will be mediators; and each subscale of the Depression, Anxiety, and Stress Scale (DASS-21; Henry & Crawford, 2005) will be the dependent variable in separate analyses. Relationships between the study variables and Asian subgroup (i.e., East, Southeast, and South Asian) will also be examined. While analyses are currently ongoing, preliminary findings suggest that strategies to cope with discrimination and mental health outcomes vary between East Asians, Southeast Asians, and South Asians. Additionally, preliminary findings suggest that the use of substance use and detachment to cope with discrimination explains the relationship between low critical reflection and mental health outcomes. Findings have implications for encouraging mental health specialists and educators to have open conversations about racism while helping those who experience discrimination cope in healthy ways. Thus, this research can contribute to improved psychological well-being of Asian American young adults.
ContributorsInocentes, Angeline (Author) / Ahn, Lydia (Thesis director) / Tran, Alisia (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / College of Integrative Sciences and Arts (Contributor) / School of Human Evolution & Social Change (Contributor)
Created2023-12
162269-Thumbnail Image.png
Description

As the use of social media becomes more prevalent, especially in adolescents and young adults, there is a growing need to understand how social media use affects psychological well-being in the emerging adult population. Prior research has found that exposure to nature reduces stress and increases attention in comparison to

As the use of social media becomes more prevalent, especially in adolescents and young adults, there is a growing need to understand how social media use affects psychological well-being in the emerging adult population. Prior research has found that exposure to nature reduces stress and increases attention in comparison to urban environments, but nature has not been studied as a way to reduce the potentially negative effects of social media. The current study aimed to determine if viewing social media or nature for a brief time affected psychological well-being, social comparisons, future self-identification, and awe, and to test whether viewing nature scenes could buffer the effects of viewing social media. Data was collected from 275 participants using a survey on Amazon Mechanical Turk. Results showed that emerging adults exposed to nature scenes had significantly less negative affect compared to those exposed to their social media feeds. Exploratory analyses showed that those who spent more time outside tended to experience decreased negative affect when they viewed both social media and nature photos, but those who spent more time outside experienced increased negative affect when only viewing social media. Those who used social media more often generally experienced lower negative affect. Findings show that relations between humans, social media, and nature, are complex, and further research into these relations and their underlying causes may be beneficial.

ContributorsHall, Megan (Author) / Kwan, Virginia (Thesis director) / Corbin, William (Committee member) / Kenrick, Douglas (Committee member) / McMichael, Samantha (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / Watts College of Public Service & Community Solut (Contributor) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor)
Created2021-12
187347-Thumbnail Image.png
Description
Previous work suggests that lower-income individuals are more likely to engage in mutual aid as a means to manage risk, giving rise to a psychology that is other-oriented, including an empathetic disposition and a proclivity to help people in need. While no study has directly investigated whether helping in times

Previous work suggests that lower-income individuals are more likely to engage in mutual aid as a means to manage risk, giving rise to a psychology that is other-oriented, including an empathetic disposition and a proclivity to help people in need. While no study has directly investigated whether helping in times of need increases dispositional empathic concern over time, this assumption is deep-seated among social psychologists. Employing a two-year longitudinal survey of US adults (N = 915), I show that people who experience more needs report helping others when in need a greater number of times, in turn leading to a small but positive increase in their empathetic disposition. This study also identifies the types of needs that elicit empathic concern (i.e., those that arise from unpredictable sources of risk), and shows why cultivating an empathetic disposition is likely to pay off in the long run: those who provide help are more likely to receive help during future times of need. Moreover, this study identifies the types of targets for whom providing help might cultivate an empathetic disposition: those with whom people are likely to share lower interdependence. While previous theoretical frameworks posit that empathic concern selectively directs investment towards interdependent others, providing help to non-interdependent targets might allow people to build positive interdependence with prospective risk pooling partners. Cultivating an empathetic disposition and building interdependence with prospective risk pooling partners can allow people to manage needs that arise from unpredictable sources of risk.
ContributorsGuevara Beltran, Diego (Author) / Aktipis, Athena (Thesis advisor) / Hruschka, Daniel (Committee member) / Kenrick, Douglas (Committee member) / Shiota, Michelle (Committee member) / Arizona State University (Publisher)
Created2023