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Testing the domain-specificity of the disease-avoidance and self-protection systems

Description

An emerging body of literature suggests that humans likely have multiple threat avoidance systems that enable us to detect and avoid threats in our environment, such as disease threats and physical safety threats. These systems are presumed to be domain-specific, each handling one class of potential threats, and previous research…

An emerging body of literature suggests that humans likely have multiple threat avoidance systems that enable us to detect and avoid threats in our environment, such as disease threats and physical safety threats. These systems are presumed to be domain-specific, each handling one class of potential threats, and previous research generally supports this assumption. Previous research has not, however, directly tested the domain-specificity of disease avoidance and self-protection by showing that activating one threat management system does not lead to responses consistent only with a different threat management system. Here, the domain- specificity of the disease avoidance and self-protection systems is directly tested using the lexical decision task, a measure of stereotype accessibility, and the implicit association test. Results, although inconclusive, more strongly support a series of domain-specific threat management systems than a single, domain- general system

ContributorsAnderson, Uriah Steven (Author) / Kenrick, Douglas T. (Thesis advisor) / Shiota, Michelle N. (Committee member) / Neuberg, Steven L. (Committee member) / Becker, David V (Committee member) / Arizona State University (Publisher)

Created2011

LEARNING HOW TO RECOGNIZE CONTEXT AND EMOTIONS FROM FACIAL EXPRESSION

Description

Humans use emotions to communicate social cues to our peers on a daily basis. Are we able to identify context from facial expressions and match them to specific scenarios? This experiment found that people can effectively distinguish negative and positive emotions from each other from a short description. However, further…

Humans use emotions to communicate social cues to our peers on a daily basis. Are we able to identify context from facial expressions and match them to specific scenarios? This experiment found that people can effectively distinguish negative and positive emotions from each other from a short description. However, further research is needed to find out whether humans can learn to perceive emotions only from contextual explanations.

ContributorsCulbert, Bailie (Author) / Hartwell, Leland (Thesis director) / McAvoy, Mary (Committee member) / School of Life Sciences (Contributor) / School of Criminology and Criminal Justice (Contributor) / Barrett, The Honors College (Contributor)

Created2021-05

A Multivariate Analysis of Life History Traits Across Species and Their Statistical Power to Predict Cancer Prevalence

Description

Cancer rates vary between people, between cultures, and between tissue types, driven by clinically relevant distinctions in the risk factors that lead to different cancer types. Despite the importance of cancer location in human health, little is known about tissue-specific cancers in non-human animals. We can gain significant insight into…

Cancer rates vary between people, between cultures, and between tissue types, driven by clinically relevant distinctions in the risk factors that lead to different cancer types. Despite the importance of cancer location in human health, little is known about tissue-specific cancers in non-human animals. We can gain significant insight into how evolutionary history has shaped mechanisms of cancer suppression by examining how life history traits impact cancer susceptibility across species. Here, we perform multi-level analysis to test how species-level life history strategies are associated with differences in neoplasia prevalence, and apply this to mammary neoplasia within mammals. We propose that the same patterns of cancer prevalence that have been reported across species will be maintained at the tissue-specific level. We used a combination of factor analysis and phylogenetic regression on 13 life history traits across 90 mammalian species to determine the correlation between a life history trait and how it relates to mammary neoplasia prevalence. The factor analysis presented ways to calculate quantifiable underlying factors that contribute to covariance of entangled life history variables. A greater risk of mammary neoplasia was found to be correlated most significantly with shorter gestation length. With this analysis, a framework is provided for how different life history modalities can influence cancer vulnerability. Additionally, statistical methods developed for this project present a framework for future comparative oncology studies and have the potential for many diverse applications.

ContributorsFox, Morgan Shane (Author) / Maley, Carlo C. (Thesis director) / Boddy, Amy (Committee member) / Compton, Zachary (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)

Created2021-05

Plasmodium Cost of Resistance and Life Stage Development within the Mosquito Vector

Description

Hundreds of thousands of people die annually from malaria; a protozoan of the genus Plasmodium is responsible for this mortality. The Plasmodium parasite undergoes several life stages within the mosquito vector, the transition between which require passage across the lumen of the mosquito midgut. It has been observed that in…

Hundreds of thousands of people die annually from malaria; a protozoan of the genus Plasmodium is responsible for this mortality. The Plasmodium parasite undergoes several life stages within the mosquito vector, the transition between which require passage across the lumen of the mosquito midgut. It has been observed that in about 15% of parasites that develop ookinetes in the mosquito abdomen, sporozoites never develop in the salivary glands, indicating that passage across the midgut lumen is a significant barrier in parasite development (Gamage-Mendis et al., 1993). We aim to investigate a possible correlation between passage through the midgut lumen and drug-resistance trends in Plasmodium falciparum parasites. This study contains a total of 1024 Anopheles mosquitoes: 187 Anopheles gambiae and 837 Anopheles funestus samples collected in high malaria transmission areas of Mozambique between March and June of 2016. Sanger sequencing will be used to determine the prevalence of known resistance alleles for anti-malarial drugs: chloroquine resistance transporter (pfcrt), multidrug resistance (pfmdr1) gene, dihydropteroate synthase (pfdhps) and dihydrofolate reductase (pfdhfr). We compare prevalence of resistance between abdomen and head/thorax in order to determine whether drug resistant parasites are disproportionately hindered during their passage through the midgut lumen. A statistically significant difference between resistance alleles in the two studied body sections supports the efficacy of new anti-malarial gene surveillance strategies in areas of high malaria transmission.

ContributorsPhillips, Keeley Isabella (Author) / Huijben, Silvie (Thesis director) / Gile, Gillian (Committee member) / Young, Steven (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)

Created2021-05

The effects of scarcity and self-esteem on the experience of envy

Description

Envy may be an emotion shaped by evolution to resolve large resource disparities in zero-sum ancestral environments. Previous research has found evidence for two types of envy: benign envy, which drives greater effort and self-improvement; and malicious envy, which drives hostility toward the better-off target. We predicted that perceived resource…

Envy may be an emotion shaped by evolution to resolve large resource disparities in zero-sum ancestral environments. Previous research has found evidence for two types of envy: benign envy, which drives greater effort and self-improvement; and malicious envy, which drives hostility toward the better-off target. We predicted that perceived resource scarcity would stoke either type, moderated by individual differences. Specifically, we predicted that high self-esteem would steer people toward benign envy and self-improvement, whereas narcissism would spark malicious envy. After completing the Rosenberg self-esteem scale and the Narcissism Personality Inventory (NPI-16), participants were randomly assigned to either read an article detailing severe cuts to university financial aid budgets (scarcity) or an article summarizing various forms of financial aid (control). Each article ended with the same envy-inducing paragraph about a particularly affluent scholarship-winner, after which participants completed a measure of both envy types, capturing feelings, appraisals, and behavioral tendencies. Results show that self-esteem predicts less malicious envy, while narcissism and scarcity predict more. Self-esteem and narcissism interact such that self-esteem dampens the effect of narcissism on malicious envy. Self-esteem predicted benign envy when narcissism was low, but not when it was high.

ContributorsDuarte, Jose L (Author) / Shiota, Michelle N. (Thesis advisor) / Kwan, Sau Y (Committee member) / Kenrick, Douglas (Committee member) / Arizona State University (Publisher)

Created2011

Development and evaluation of an intervention to increase sun protection in young women

Description

In the present research, two interventions were developed to increase sun protection in young women. The purpose of the study was to compare the effects of intervention content eliciting strong emotional responses to visual images depicting photoaging and skin cancer, specifically fear and disgust, coupled with a message of self-efficacy…

In the present research, two interventions were developed to increase sun protection in young women. The purpose of the study was to compare the effects of intervention content eliciting strong emotional responses to visual images depicting photoaging and skin cancer, specifically fear and disgust, coupled with a message of self-efficacy and benefits of sun protection (the F intervention) with an intervention that did not contain an emotional arousal component (the E intervention). Further, these two intervention conditions were compared to a control condition that contained an emotional arousal component that elicited emotion unrelated to the threat of skin cancer or photoaging (the C control condition). A longitudinal study design was employed, to examine the effects of condition immediately following the intervention, and to examine sun protection behavior 2 weeks after the intervention. A total of 352 undergraduate women at Arizona State University were randomly assigned to one of the three conditions (F n = 148, E n = 73, C n = 131). Several psychosocial constructs, including benefits of sun protection, susceptibility to and severity of photoaging and sun exposure, self-efficacy beliefs of making sun protection a daily habit, and barriers to sun protection were measured before and immediately following the intervention. Sun protection behavior was measured two weeks later. Those in the full intervention reported higher self-efficacy and severity of photoaging at immediate posttest than those in the efficacy only and control conditions. The fit of several path models was tested to explore underlying mechanisms by which the intervention affected sun protection behavior. Experienced emotion, specifically fear and disgust, predicted susceptibility and severity, which in turn predicted anticipated regret of failing to use sun protection. The relationship between this overall threat component (experienced emotion, susceptibility, severity, and anticipated regret) and intentions to engage in sun protection behavior was mediated by benefits. The present research provided evidence of the effectiveness of threat specific emotional arousal coupled with a self-efficacy and benefits message in interventions to increase sun protection. Further, this research provided additional support for the inclusion of both experienced and anticipated emotion in models of health behavior.

ContributorsMoser, Stephanie E (Author) / Aiken, Leona S. (Thesis advisor) / Shiota, Michelle N. (Committee member) / Kwan, Sau (Committee member) / Castro, Felipe (Committee member) / Arizona State University (Publisher)

Created2011

Cold populations of flies evolved larger bodies and larger wings made of larger cells

Description

We examined the evolutionary morphological responses of Drosophila melanogaster that had evolved at constant cold (16°), constant hot (25°C), and fluctuating (16° and 25°C). Flies that were exposed to the constant low mean temperature developed larger thorax, wing, and cell sizes than those exposed to constant high mean temperatures. Males…

We examined the evolutionary morphological responses of Drosophila melanogaster that had evolved at constant cold (16°), constant hot (25°C), and fluctuating (16° and 25°C). Flies that were exposed to the constant low mean temperature developed larger thorax, wing, and cell sizes than those exposed to constant high mean temperatures. Males and females both responded similarly to thermal treatments in average wing and cell size. The resulting cell area for a given wing size in thermal fluctuating populations remains unclear and remains a subject for future research.

ContributorsAdrian, Gregory John (Author) / Angilletta, Michael (Thesis director) / Harrison, Jon (Committee member) / Rusch, Travis (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)

Created2015-05

Implicit measures of homophobia and stigmatization of same-sex couples

Description

While acceptance towards same-sex marriage is gradually increasing, same-sex marriage is banned in many states within the United States. Laws that prohibit same-sex couples from marrying have been shown to increase feelings of depression, exclusion, and stigma for same-sex attracted individuals. The intention of this study was to explore the…

While acceptance towards same-sex marriage is gradually increasing, same-sex marriage is banned in many states within the United States. Laws that prohibit same-sex couples from marrying have been shown to increase feelings of depression, exclusion, and stigma for same-sex attracted individuals. The intention of this study was to explore the effect both pro- and anti-same-sex marriage advertisements have on heterosexual individuals' implicit attitudes towards same-sex couples. It was predicted that exposure to anti-same-sex advertisements would lead to viewing same-sex couples as more unpleasant and heterosexual couples as being more pleasant. However, heterosexual participants who viewed anti-same-sex marriage ads were more likely to rate heterosexual couples as being unpleasant and same-sex couples as pleasant. It is theorized that viewing anti-same-sex marriage advertisements led heterosexual individuals to report heterosexual stimuli as being more unpleasant compared to same-sex stimuli as a form of defensive processing.

ContributorsWalsh, Theodora Michelle (Author) / Newman, Matt (Thesis advisor) / Hall, Deborah (Committee member) / Salerno, Jessica (Committee member) / Arizona State University (Publisher)

Created2013

Bullying, loneliness, and future responses to stress

Description

Bully victimization has been associated with blunted cardiovascular responses to stress as well as elevated responses to stress. The difference between these altered physiological responses to stress is largely unknown. This study explored several possible moderators to the relationship between chronic stress and future cardiac output (an indicator of increased…

Bully victimization has been associated with blunted cardiovascular responses to stress as well as elevated responses to stress. The difference between these altered physiological responses to stress is largely unknown. This study explored several possible moderators to the relationship between chronic stress and future cardiac output (an indicator of increased stress) in response to future stressors. These moderators include the difference between social and physical stressors and individual levels of loneliness. Participants were administered measures of loneliness and victimization history, and led to anticipate either a "social" (recorded speech) or "non-social" (pain tolerance test ) stressor, neither of which occurred. EKG and impedance cardiography were measured throughout the session. When anticipating both stressors, loneliness and victimization were associated with increased CO. A regression revealed a three-way interaction, with change in cardiac output depending on victimization history, loneliness, and condition in the physical stressor condition. Loneliness magnified the CO output levels of non-bullied individuals when facing a physical stressor. These results suggest that non- bullied participants high in loneliness are more stressed out when facing stressors, particularly stressors that are physically threatening in nature.

ContributorsHaneline, Magen (Author) / Newman, Matt (Thesis advisor) / Salerno, Jessica (Committee member) / Miller, Paul (Committee member) / Arizona State University (Publisher)

Created2013

Sexual prejudices fluctuate according to active fundamental life goals

Description

Traditional perspectives on sexual prejudice typically focus on the distinction between heterosexual ingroup and homosexual outgroup. In contrast, I focus on an affordance-management paradigm which views prejudices as resulting not from ingroup/outgroup relations, but instead from perceptions of the threats and opportunities posed by members of different groups. Past research…

Traditional perspectives on sexual prejudice typically focus on the distinction between heterosexual ingroup and homosexual outgroup. In contrast, I focus on an affordance-management paradigm which views prejudices as resulting not from ingroup/outgroup relations, but instead from perceptions of the threats and opportunities posed by members of different groups. Past research has demonstrated that non-heterosexual target groups are perceived to pose a variety of threats, including threats to the socialization of young children, of child molestation, of disease, and to values. My research, however, suggests sexual prejudices arise for college students from beliefs that certain sexual orientation groups pose threats of unwanted sexual interest. For young adults, mating concerns are salient and should define relevant threats and opportunities--including those that might drive prejudices. For individuals with different active motivations, however, different threats and opportunities and threats are salient, and so the threats driving sexual prejudices may also differ. I extend my past research to consider how activating different fundamental goals (e.g., disease avoidance, parenting) alters patterns of sexual prejudice. I posit that activating disease concerns will increase prejudice specifically toward non-heterosexuals associated with disease (gay and bisexual me)--but not other non-heterosexuals (lesbians and bisexual women)--whereas activating offspring care will increase prejudice toward all non-heterosexual target groups, as all are perceived to pose socialization threats. To test this, heterosexual participants were randomly assigned to a parenting or disease-avoidance goal activation, or control condition, and then rated their general negativity towards heterosexual, bisexual, and homosexual male and female targets. They also rated their perceptions of the extent to which each target posed unwanted sexual interest, socialization, and disease threats. Contrary to predictions, activating parenting and disease avoidance systems failed to affect sexual prejudices. Furthermore, although the pattern of observed data was largely consistent with previously observed patterns, women's attitudes towards gay men in the control condition were more negative than that found in previous studies, as were men's attitudes towards bisexual and lesbian women. Multiple mechanisms underlie sexual prejudices, and research is needed to better understand the circumstances under which alternative mechanisms are engaged and have their effects.

ContributorsPirlott, Angela (Author) / Neuberg, Steven L. (Thesis advisor) / Kenrick, Douglas T. (Committee member) / Mackinnon, David P. (Committee member) / Shiota, Michelle N. (Committee member) / Arizona State University (Publisher)

Created2012

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