Matching Items (6)
Filtering by
- All Subjects: psychology
- All Subjects: Chronic Pain
Description
Fibromyalgia (FM) is a chronic musculoskeletal disorder characterized by widespread pain, fatigue, and a variety of other comorbid physiological and psychological characteristics, including a deficit of positive affect. Recently, the focus of research on the pathophysiology of FM has considered the role of a number of genomic variants. In the current manuscript, case-control analyses did not support the hypothesis that FM patients would differ from other chronic pain groups in catechol-O-methyltransferase (COMT) and mu-opioid receptor (OPRM1) genotype. However, evidence is provided in support of the hypothesis that functional single nucleotide polymorphisms on the COMT and OPRM1 genes would be associated with risk and resilience, respectively, in a dual processing model of pain-related positive affective regulation in FM. Forty-six female patients with a physician-confirmed diagnosis of FM completed an electronic diary that included once-daily assessments of positive affect and soft tissue pain. Multilevel modeling yielded a significant gene X environment interaction, such that individuals with met/met genotype on COMT experienced a greater decline in positive affect as daily pain increased than did either val/met or val/val individuals. A gene X environment interaction for OPRM1 also emerged, indicating that individuals with at least one asp allele were more resilient to elevations in daily pain than those homozygous for the asn allele. In sum, the findings offer researchers ample reason to further investigate the contribution of the catecholamine and opioid systems, and their associated genomic variants, to the still poorly understood experience of FM.
ContributorsFinan, Patrick Hamilton (Author) / Zautra, Alex (Thesis advisor) / Davis, Mary (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Presson, Clark (Committee member) / Arizona State University (Publisher)
Created2011
Description
Research has suggested that lonely people demonstrate distinct differences from nonlonely people in their behaviors, mood, and interpersonal experiences. Lonely people who are also enduring a chronic pain condition may be at an especially high risk for negative outcomes because of simultaneous issues such as stigma, mood disturbances, and pain-related disability. The current study examined chronic and transitory loneliness in a sample of 123 chronic pain patients. Participants completed daily diaries assessing the occurrence of positive and negative interpersonal events, appraisals of interpersonal events, pain, and mood. Multilevel modeling was used to examine effects of being a lonely person as well as having a lonely episode on daily life. Results indicated that both chronic and transitory loneliness were associated with more frequent negative and less frequent positive interpersonal events, higher levels of pain, more negative and less positive affect, and more stress and less enjoyment from social interactions. Loneliness did not affect reactivity to negative interpersonal events, but did influence responsivity to positive interpersonal events such that lonely people had greater boosts in enjoyment when experiencing more positive interpersonal events than usual. These findings suggest that both lonely people and individuals experiencing a lonely episode experience more negative consequences in their daily lives than nonlonely people. However, they can benefit from engaging in more frequent positive interpersonal events, which can help to inform future clinical interventions for lonely, chronic pain patients.
ContributorsDempsey, Laurie (Author) / Davis, Mary (Thesis advisor) / Zautra, Alex (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2012
Description
In rehabilitation settings, activity limitation can be a significant barrier to recovery. This study sought to examine the effects of state and trait level benefit finding, positive affect, and catastrophizing on activity limitation among individuals with a physician-confirmed diagnosis of either Osteoarthritis (OA), Fibromyalgia (FM), or a dual diagnosis of OA/FM. Participants (106 OA, 53 FM, and 101 OA/FM) who had no diagnosed autoimmune disorder, a pain rating above 20 on a 0-100 scale, and no involvement in litigation regarding their condition were recruited in the Phoenix metropolitan area for inclusion in the current study. After initial questionnaires were completed, participants were trained to complete daily diaries on a laptop computer and instructed to do so a half an hour before bed each night for 30 days. In each diary, participants rated their average daily pain, benefit finding, positive affect, catastrophizing, and activity limitation. A single item, "I thought about some of the good things that have come from living with my pain" was used to examine the broader construct of benefit finding. It was hypothesized that state and trait level benefit finding would have a direct relation with activity limitation and a partially mediated relationship, through positive affect. Multilevel modeling with SAS PROC MIXED revealed that benefit finding was not directly related to activity limitation. Increases in benefit finding were associated, however, with decreases in activity limitation through a significant mediated relationship with positive affect. Individuals who benefit find had a higher level of positive affect which was associated with decreased activity limitation. A suppression effect involving pain and benefit finding at the trait level was also found. Pain appeared to increase the predictive validity of the relation of benefit finding to activity limitation. These findings have important implications for rehabilitation psychologists and should embolden clinicians to encourage patients to increase positive affect by employing active approach-oriented coping strategies like benefit finding to reduce activity limitation.
ContributorsKinderdietz, Jeffrey Scott (Author) / Zautra, Alex (Thesis advisor) / Davis, Mary (Committee member) / Barrera, Manuel (Committee member) / Okun, Morris (Committee member) / Arizona State University (Publisher)
Created2012
Description
Prevailing models describing coping with chronic pain posit that it is a complex day-to-day process that can involve psychosocial factors, including cognitive appraisals about pain, interpersonal challenges such as distressed social relationships, and reduced engagement in enjoyable experiences. Few studies, however, have applied a process-oriented approach to elaborate the relations between key pain-related appraisals, social environmental factors, and self-efficacy, a key self-appraisal for successful adaptation to chronic pain. This study used within-day daily diary methodology to test the following hypotheses: (a) increases in morning pain catastrophizing predict decreases in end of day pain self-efficacy; (b) increases in perceived stressfulness of interpersonal relations occurring during the day exacerbate the negative effects of morning catastrophizing on end-of-day pain self-efficacy; and (c) increases in perceived enjoyment of interpersonal relations occurring during the day mitigate the negative effects of morning pain catastrophizing on end of day pain self-efficacy. Within-day measures, including morning pain catastrophizing, afternoon interpersonal stress and enjoyment ratings, and end-of-day pain self-efficacy, were collected for 21 days via an automated phone system from 223 participants with widespread chronic pain. The use of diary data allowed for examination of time-varying processes related to pain adaptation. Results of multilevel regression models indicated that, consistent with prediction, increases in morning pain catastrophizing and predicted decreases in end-of-day pain self-efficacy. Contrary to prediction, changes in midday interpersonal enjoyment and stress did not moderate the within-day catastrophizing-efficacy relation. Rather increases in midday enjoyment and stable individual differences in enjoyment predicted end-of-day efficacy. Overall, findings suggest a within-day relation between pain cognition and social context and subsequent self-efficacy, and highlight potential targets for intervention in chronic pain.
ContributorsThummala, Kirti (Author) / Davis, Mary C. (Thesis advisor) / Zautra, Alex (Committee member) / Okun, Morris (Committee member) / Arizona State University (Publisher)
Created2018
Description
Humans require sufficient social understanding and connectedness to thrive (Baumeister & Leary, 1995). The current study evaluates the effectiveness of the Social Intelligence Institute's training program pilot. At a middle school in Phoenix, Arizona, students in a 7th and 8th grade class participated in this pilot program during the spring of 2013. Pre- and post-test questionnaires administered indicated changes in participants reported measures of Perspective Taking, Empathetic Concern, Interpersonal Expectations, and Relationship Self-Efficacy. The program consists of seven modules, each with several sessions, including instructional videos with reflection questions and class discussions. It was predicted that there would be a significant increase in mean scores for the dependent variables in the questionnaire mentioned above from the pre-test to the post-test. However, the null hypotheses were not rejected; statistical significance in t-tests of the measured variables were not met. Yet, the program was more effective for 8th graders than for 7th graders for Perspective Taking. This study of the SI pilot program demonstrates areas of improvement and provides support for wider implementation in the future.
ContributorsBailey, Jonathan Donald (Author) / Zautra, Alex (Thesis director) / Glenberg, Arthur (Committee member) / Short, Robert (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2013-12
Description
An abundance of data has established the links between both pain-related cognitions and relationship attachment qualities in the experience of pain, including long-term functional health in chronic pain patients. However, relatively few studies have explored the dynamic relation between pain and pain-related cognitions within a day, and no studies have tested the moderating role of relationship attachment on the within-day cognition—pain association in chronic pain patients. The objectives of this study were to: 1) assess whether late morning pain flares predicted changes in afternoon positive and negative pain-related cognitive appraisals, and whether these changes in turn predicted end-of-day pain, and 2) explore whether adult attachment anxiety moderated the pain-cognition relation in individuals with chronic pain due to fibromyalgia. One hundred and seventy four partnered individuals with fibromyalgia completed initial assessments of demographics and attachment anxiety, and subsequently completed electronic assessments of pain intensity and positive and negative cognitive pain-related appraisals three times a day for three weeks. Multilevel structural equation modeling established that a latent negative cognitive appraisal factor (encompassing shared variance from catastrophizing, pain irritation, and self-criticism related to pain) mediated the link between late morning and end-of-day pain intensity, in line with the hypothesis. Analyses also provided some support for a mediating role for a positive cognitive appraisal factor (a composite of pain control, pain self-efficacy, and feeling pain without reacting) in the daily course of pain; the mediated effect for positive appraisals was weaker than the mediated effect of negative appraisals, but was sustained in a model that included negative appraisals. Inconsistent with prediction, attachment anxiety did not moderate the within-day links between pain and cognitions. These findings establish the dynamic links within day between pain and pain-related cognitions, and highlight the potential impact of both negative and positive cognitions on daily pain regulation. They point to the value of broadening cognitive-behavioral treatment strategies for chronic pain patients to target not only negative but also positive cognitions.
ContributorsTaylor, Shannon Stark (Author) / Davis, Mary C. (Thesis advisor) / Zautra, Alex (Committee member) / Okun, Morris (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2015