Matching Items (12)
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Description
Health and Wealthness is a podcast where your hosts, Emily Weigel and Hanaa Khan discuss pressing and trending topics about health and wealth that everyone should know about. Our first four episodes focus on the opioid crisis. Both the science and healthcare sides. We then go on to talk about burnout and mental health in a conversational episode.
ContributorsKhan, Hanaa S (Co-author) / Weigel, Emily (Co-author) / Olive, Foster (Thesis director) / Bonfiglio, Thomas (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
ContributorsRizvi, Hasan (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
Description
Our current understanding of the mitochondrial genome was revolutionized in 2015 with the discovery of short open reading frames (sORFs) that produced protein products called mitochondrial-derived peptides (MDPs). Interestingly, unlike other proteins produced by the organelle, these MDPs are not directly involved in the electron transport chain but rather serve the role of metabolic regulators. In particular, one of these peptides called MOTS-c has been shown to regulate glucose and fat metabolism in an AMPK-dependent manner. With its capacity to enter the mitochondria and impact gene expression, MOTS-c has also displayed the ability to increase aerobic exercise performance by triggering elevated synthesis of the HO-1 antioxidant. Overall these findings position MOTS-c as a promising treatment for metabolic diseases as well as a potential dietary supplement to boost ATP availability.
ContributorsRizvi, Hasan (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
ContributorsRizvi, Hasan (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
Description
In the past, researchers have studied the elements of speech and how they work together in the human brain. Auditory feedback, an important aid in speech production, provides information to speakers and allows them to gain an understanding if the prediction of their speech matches their production. The speech motor system uses auditory goals to determine errors in its auditory output during vowel production. We learn from discrepancies between our prediction and auditory feedback. In this study, we examined error assessment processes by systematically manipulating the correspondence between speech motor outputs and their auditory consequences while producing speech. We conducted a study (n = 14 adults) in which participants’ auditory feedback was perturbed to test their learning rate in two conditions. During the trials, participants repeated CVC words and were instructed to prolong the vowel each time. The adaptation trials were used to examine the reliance of auditory feedback and speech prediction by systematically changing the weight of auditory feedback. Participants heard their perturbed feedback through insert earphones in real time. Each speaker’s auditory feedback was perturbed according to task-relevant and task-irrelevant errors. Then, these perturbations were presented to subjects gradually and suddenly in the study. We found that adaptation was less extensive with task-irrelevant errors, adaptation did not saturate significantly in the sudden condition, and adaptation, which was expected to be extensive and faster in the task-relevant condition, was closer to the rate of adaptation in the task-irrelevant perturbation. Though adjustments are necessary, we found an efficient way for speakers to rely on auditory feedback more than their prediction. Furthermore, this research opens the door to future investigations in adaptation in speech and presents implications for clinical purposes (e.g. speech therapy).
ContributorsLukowiak, Ariana (Author) / Daliri, Ayoub (Thesis director) / Rogalsky, Corianne (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / College of Health Solutions (Contributor, Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this project was to discuss the physiological effects of isolation on the human body and how the body adapts. Through reviewing stories and studies of social and perceptual isolation, the adaptations of the human mind are detailed. This project explores the experiences of prisoners, sensory deprivation tanks, cave explorations, as well as studies involving monkeys and carpenter ants. The adaptations witnessed include hallucinations, increased mortality, anxiety, agitation, altered sense of time, delayed response, and lowered blood pressure. Knowing the factors surrounding the isolation experience is crucial to understand the presenting adaptation methods. These factors include duration, voluntary or involuntary participation, mental strength, and the restriction level of the isolation.
DISCLAIMER: Due to the unexpected COVID-19 pandemic, the attached podcast is a draft recording in lieu of the final recording
DISCLAIMER: Due to the unexpected COVID-19 pandemic, the attached podcast is a draft recording in lieu of the final recording
ContributorsSidhu, Nimrit (Co-author) / Deacon, Hannah (Co-author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / School of Social Work (Contributor) / College of Health Solutions (Contributor) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
****Project Disclaimer: Unfortunately due to the COVID-19 outbreak during Spring 2020, ASU shut down in-person classes and campus facilities as means to prevent the spread of the virus. This meant though that a polished final podcast recording was unable to be made. Instead, a first-run, practice podcast recording that was recorded before the shut down is uploaded in its stead as a reference as to how the final was intended to sound and be produced. ****
Cellular hypertrophy is an anaerobically-based, adaptive process that mammalian skeletal muscle undergoes in response to damage resulting from unaccustomed force generation by the muscle. Hypertrophy allows for the muscle tissue to recover from the immediate injury and also to be rebuilt more capable of withstanding producing the same amount of force without injury, should it happen again. This means the end result of an adapted muscle is an overall more efficient tissue. The ability to regenerate after damage to the structure and function of the muscle tissue is a highly orchestrated event involving multiple steps and key events to occur. Most briefly, a mechanical load is attempted to be lifted but due to demanding a high amount of contractile force to lift, it causes microdamage to the structural and contractile elements of muscle fiber’s sarcomeres. In addition to an inflammatory response, satellite cells, as a part of a myogenic response, are activated to invade the fiber and then permanently reside inside to produce new proteins that will replace the damaged and necrotized proteins. This addition of cellular content, repeated over multiple times, results in the increased diameter of the fibers and manifests in the visual appearance of skeletal muscle hypertrophy. These steps have been listed off devoid of the contexts in which it takes for these to occur and will be addressed within this thesis.
Cellular hypertrophy is an anaerobically-based, adaptive process that mammalian skeletal muscle undergoes in response to damage resulting from unaccustomed force generation by the muscle. Hypertrophy allows for the muscle tissue to recover from the immediate injury and also to be rebuilt more capable of withstanding producing the same amount of force without injury, should it happen again. This means the end result of an adapted muscle is an overall more efficient tissue. The ability to regenerate after damage to the structure and function of the muscle tissue is a highly orchestrated event involving multiple steps and key events to occur. Most briefly, a mechanical load is attempted to be lifted but due to demanding a high amount of contractile force to lift, it causes microdamage to the structural and contractile elements of muscle fiber’s sarcomeres. In addition to an inflammatory response, satellite cells, as a part of a myogenic response, are activated to invade the fiber and then permanently reside inside to produce new proteins that will replace the damaged and necrotized proteins. This addition of cellular content, repeated over multiple times, results in the increased diameter of the fibers and manifests in the visual appearance of skeletal muscle hypertrophy. These steps have been listed off devoid of the contexts in which it takes for these to occur and will be addressed within this thesis.
ContributorsDwyer, Lauren Mingna Carol (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffery (Committee member) / School of Life Sciences (Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow it to go extended periods of time consuming little to no food. These adaptations also allow the body to recover quickly once food becomes available. They include changes in metabolism that allow different fuel sources to be used for energy, the storing of excess energy absorbed from food in the forms of glycogen and fat to be used in between meals, and a reduction in the basal metabolic rate in response to starvation, as well as physiological changes in the small intestines. Even in places where starvation is not a concern today, these adaptations are still important as they also have an effect on weight gain and dieting in addition to promoting survival when the body is in a starved state.
Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
ContributorsPhlipot, Stephanie Anne (Author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / School of Molecular Sciences (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The goal of this paper is to describe the current understanding of how a human’s remaining senses are affected by the onset of blindness through physiological adaptations. The main focuses of this paper stem around the brain and how it adapts to blindness through mechanisms such as neuroplasticity. This paper will explore the increased acuity of both tactile and auditory processing as well as spatial navigation resulting from the onset of blindness. This paper will also explore the enhanced ability of the blind to echolocate as well as the mechanisms of homeostasis that underlie this ability. Finally, this paper will report on the lack of enhancement for the senses of taste and smell in humans after the onset of blindness and possible reasons why there are no observed increases in potential. It is the hope of the writers that this paper will cover the current state of knowledge on the phenomenon of adaptations resulting from the onset of blindness to such an extent that this information can be presented in a podcast format later on.
Disclaimer: Due to the COVID-19 global pandemic, the final outcomes of this project were impacted and limited. Therefore, the rough draft practice podcast session has been uploaded to accompany the written thesis portion as final recordings could not be recorded at this time.
Disclaimer: Due to the COVID-19 global pandemic, the final outcomes of this project were impacted and limited. Therefore, the rough draft practice podcast session has been uploaded to accompany the written thesis portion as final recordings could not be recorded at this time.
ContributorsMoyzes, Hannah (Co-author) / Fox, Dylan (Co-author) / Hyatt, JP (Thesis director) / Kingsbury, Jeffrey (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Recovery from exercise has become an evolving aspect of all sports performance. Increased research has led numerous individuals to understand and utilize the modalities that have become available. Methods such as Cold Water Immersion (CWI), Contrast Water Therapy (CWT), and Hot Water Immersion (HWI) are some of the modalities growing in popularity as well as utilization by athletes across all sports. This paper aims to examine and analyze evidence across several research journals that evaluate the effectiveness and also application of these recovery methods. Cold and heat exposures on the body can have a drastic positive impact on athletic performance. However, without the correct knowledge and guidance, these methods can augment, mitigate, and even diminish the effects of adaptation and exercise. This thesis aims to examine research journals and extract specific practices based on empirical evidence. This is to form proper deliverables and protocols for athletes to use for ideal adaptations and recovery for performance.
ContributorsHouse, Grant (Author) / Levinson, Simin (Thesis director) / Behm, Herbert (Committee member) / Vezina, Jesse (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor) / Sandra Day O'Connor College of Law (Contributor)
Created2022-05