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- Creators: Barrett, The Honors College
Description
Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Community Music Therapy for Cultural Cohesion is the name of the research initiative to create a community music therapy program that addresses community attitudes toward cultural diversity. The program created is titled "Many Peoples, One Voice." Theories and findings in the field of social psychology regarding the formation of intergroup bias and how to prevent it from taking hold inform the goals of the program. Current practices in and theories on community music therapy inform the content, qualities, and perspective of the program. Information from the field of ethnomusicology inform the specific world music traditions incorporated into the program. The culmination of this research and the program it birthed is described in detail to promote a better understanding of the goals, activities, cultural handouts, additional content considerations, and structure of the program as well as the populations it may serve and the adaptions it may include. Finally, the program is related to the current trends in the field of music therapy and its potential to expand into nontraditional need and population areas is considered.
ContributorsOstrowski, Jennifer Lauren (Author) / Rio, Robin (Thesis director) / Little, Bliss (Committee member) / School of Music (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
This project focuses on techniques contemporary American poets use in their work. Ten different poetry collections are analyzed for dominant writing styles and techniques, which I then apply to my own poems, concentrating on modeling that particular poet. I then reflect on those poems through an evaluation of my writing process, how those techniques were implemented, and how they affected the poem. In addition to these reviews and reflections, I also wrote three articles about the literary community and what I've learned from my interactions in that community. All these materials are organized into a website, which shows the connections between the different writings via links and menus. Creating this website brings all the materials together to demonstrate my growth as a poet, writer, and designer. This heavy focus on poetry and analysis has helped sharpen my critical thinking skills and has better prepared me for a career in design and journalism.
ContributorsHansen, Elizabeth Sarah (Author) / Murphy, Patricia (Thesis director) / Savard, Jeannine (Committee member) / Barrett, The Honors College (Contributor) / Department of English (Contributor) / Hugh Downs School of Human Communication (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor)
Created2015-05
Description
The transition from high school to college is marked by many changes, one of the most significant being the increased accessibility of alcohol, putting college students at high risk for alcohol-related consequences. It is imperative to identify factors that can protect young adults against these risks during this critical period. Although peers become increasingly influential in college, extant literature has shown that parents still have an impact on their children's behavior during this time. While parents spend less time with their children after college matriculation, they may indirectly protect against risky drinking behaviors by instilling certain values into their children before they make this transition. Using data from a large sample of students during their senior year of high school and their freshman year of college, the current study sought to examine interactive effects of parental communication and parental knowledge and caring on drinking behavior, and the extent to which internalization of personal drinking values mediate these effects. The primary study hypotheses were tested using path analysis conducted in Mplus 7.0. Full information maximum likelihood (FIML) estimation was utilized to estimate missing data and bootstrapping was used to address non-normality in the data. Results showed that, for those whose parents were high in knowledge and caring, higher levels of communication were associated with lower risk for alcohol use and problems at wave 3 through less permissive drinking values at wave 1. This finding has important implications for prevention approaches designed to reduce risk for heavy drinking and related problems during the transition to college.
ContributorsHartman, Jessica Danielle (Author) / Corbin, William (Thesis director) / Knight, George (Committee member) / Chassin, Laurie (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
A study on the effectiveness of different graphic design elements, such as color and shape, in political communication over a digital medium. The study was conducted through an online survey of young adults (18-25 years old). Participants' preferences for the design elements are compared to their online and offline political participation and their primary sources for political information.
ContributorsRyan, Daiquiri Ice (Author) / Lennon, Tara (Thesis director) / Woodall, Gina (Committee member) / Blyler, Lisa (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / School of Politics and Global Studies (Contributor)
Created2014-05
Description
The Community Action Research Experiences (CARE) Program collaborated with Maricopa Association of Government to assess the needs of domestic violence victim advocates in Maricopa County to determine how their work could be enhanced through additional advocacy training and support services. Data were collected from 87 participants over a one-month period by distribution of an electronic survey. Sixty participants completed the survey, and 27 partially completed the survey. Only the data received from the 60 participants who completed the survey were used in reporting the results. The results indicated a perceived need for more training for advocates, specifically for advocates during their first year on the job. The results also indicated that while domestic violence victim advocates work in different agencies, they expressed significant interest in working collaboratively with advocates from other fields to increase cooperation and coordination among agencies to ensure that victims receive the best possible services.
ContributorsSilva, Nathalea (Author) / Bodman, Denise (Thesis director) / Dumka, Larry (Committee member) / Tenney, Renae (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
The Phoenix-Metro area currently has problems with its transportation systems. Over-crowded and congested freeways have slowed travel times within the area. Express bus transportation and the existence of "High Occupancy" lanes have failed to solve the congestion problem. The light rail system is limited to those within a certain distance from the line, and even the light rail is either too slow or too infrequent for a commuter to utilize it effectively. To add to the issue, Phoenix is continuing to expand outward instead of increasing population density within the city, therefore increasing the time it takes to travel to downtown Phoenix, which is the center of economic activity. The people of Phoenix and its surrounding areas are finding that driving themselves to work is just as cost-effective and less time consuming than taking public transportation. Phoenix needs a cost-effective solution to work in co- existence with improvements in local public transportation that will allow citizens to travel to their destination in just as much time, or less time, than travelling by personal vehicle.
ContributorsSerfilippi, Jon (Author) / Ariaratnam, Samuel (Thesis director) / Pendyala, Ram (Committee member) / Pembroke, Jim (Committee member) / Barrett, The Honors College (Contributor) / Ira A. Fulton School of Engineering (Contributor)
Created2012-12
Description
College students who may be living on their own for the first time are faced with a slew of new challenges, which include making healthy lifestyle choices. The purpose of this study involves investigating how well Arizona State University freshmen students take care of their health (regarding nutrition, purposeful exercise, alcohol consumption and sleep patterns) compared to other college freshmen throughout the United States. This study used data from the ASU Wellness department and the American College Health Association (ACHA) to compare these aspects of health and find out which areas ASU health promotions efforts should focus on to help educate freshmen and improve their health for the future. The writer also researched past studies to find the best ways to communicate health information to college freshmen via online media. Findings indicate both ASU freshmen and students from various U.S. universities fall short of meeting current health recommendations, and a need exists for further research to identify the best practices to effectively reach these students through the Internet and commonly used online platforms.
ContributorsKunkel, Katie Lynn (Author) / Chiarelli, Dean (Thesis director) / Aguila, Holly (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2014-05
Description
Several different queer feminist zines, along with the author's experiences in queer feminist zine making, are examined using the lens of J. Jack Halberstam's The Queer Art of Failure. Particular attention is paid to zines' unique composition from a variety of unexpected sources, and their subsequent ability to act as counterhegemonic documents. Queer feminist zine makers' critical engagement with the concept of community is also discussed.
ContributorsPruett, Jessica Lynn (Author) / Switzer, Heather (Thesis director) / Dove-Viebahn, Aviva (Committee member) / Barrett, The Honors College (Contributor) / School of Social Transformation (Contributor) / Department of English (Contributor)
Created2014-05
DescriptionAn analysis and informal ethnography of the participatory culture in Phoenix, Arizona that identifies itself as "geeky" or "nerdy." Conducted through numerous interviews and academic research, the project looks at this active community under the scope of personal choice and togetherness.
ContributorsHuskinson, Harmony (Author) / Facinelli, Diane (Thesis director) / Scott, Suzanne (Committee member) / Barrett, The Honors College (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor)
Created2014-05