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Description
Unlike the autosomes, recombination on the sex chromosomes is limited to the pseudoautosomal regions (PARs) at each end of the chromosome. PAR1 spans approximately 2.7 Mb from the tip of the proximal arm of each sex chromosome, and a pseudoautosomal boundary between the PAR1 and non-PAR region is thought to

Unlike the autosomes, recombination on the sex chromosomes is limited to the pseudoautosomal regions (PARs) at each end of the chromosome. PAR1 spans approximately 2.7 Mb from the tip of the proximal arm of each sex chromosome, and a pseudoautosomal boundary between the PAR1 and non-PAR region is thought to have evolved from a Y-specific inversion that suppressed recombination across the boundary. In addition to the two PARs, there is also a human-specific X-transposed region (XTR) that was duplicated from the X to the Y chromosome. Genetic diversity is expected to be higher in recombining than nonrecombining regions, particularly because recombination reduces the effects of linked selection, allowing neutral variation to accumulate. We previously showed that diversity decreases linearly across the previously defined pseudoautosomal boundary (rather than drop suddenly at the boundary), suggesting that the pseudoautosomal boundary may not be as strict as previously thought. In this study, we analyzed data from 1271 genetic females to explore the extent to which the pseudoautosomal boundary varies among human populations (broadly, African, European, South Asian, East Asian, and the Americas). We found that, in all populations, genetic diversity was significantly higher in the PAR1 and XTR than in the non-PAR regions, and that diversity decreased linearly from the PAR1 to finally reach a non-PAR value well past the pseudoautosomal boundary in all populations. However, we also found that the location at which diversity changes from reflecting the higher PAR1 diversity to the lower nonPAR diversity varied by as much as 500 kb among populations. The lack of genetic evidence for a strict pseudoautosomal boundary and the variability in patterns of diversity across the pseudoautosomal boundary are consistent with two potential explanations: (1) the boundary itself may vary across populations, or (2) that population-specific demographic histories have shaped diversity across the pseudoautosomal boundary.
ContributorsCotter, Daniel Juetten (Author) / Wilson Sayres, Melissa (Thesis director) / Stone, Anne (Committee member) / Webster, Timothy (Committee member) / School of Life Sciences (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
The Mexican gray wolf (Canis lupus baileyi) is a genetically distinct subspecies of the gray wolf (Canis lupus) that was driven to the brink of extinction as a result of human persecution. The wolf is listed as Endangered under the Endangered Species Act, and a recovery program is underway in

The Mexican gray wolf (Canis lupus baileyi) is a genetically distinct subspecies of the gray wolf (Canis lupus) that was driven to the brink of extinction as a result of human persecution. The wolf is listed as Endangered under the Endangered Species Act, and a recovery program is underway in Arizona and New Mexico to restore its population. However, the wolf is struggling to recover due to high mortality, which is a result of continued human hostility toward it. This thesis examines historical and current human attitudes toward the wolf and the implications that they have had on the extermination and recovery of the subspecies. An overview is given of wolf biology, the history of wolf extermination and recovery, and recent events relating to the recovery of the wolf. Negative impacts on ranching, hunting, and human safety are the main reasons for opposition toward wolves and wolf recovery; these concerns are analyzed, and solutions to them are proposed, with the goal of addressing them while fostering non-lethal coexistence with the wolf. In addition, opposition to wolves and wolf recovery is tied in with larger socio-political issues and is influenced by the representation of the wolf in culture; these issues in the context of wolves are also analyzed.
ContributorsLenk, Heather Nicole (Author) / Smith, Andrew (Thesis director) / Minteer, Ben (Committee member) / Brown, David E. (Committee member) / School of Life Sciences (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
In the Spring of 2021, I had an internship with Butterfly Wonderland, where I worked in their conservatory and learned about the ecological relationship between butterflies and plants. As part of my internship, I encouraged guests to learn more about gardening for pollinators. That experience inspired me to complete a

In the Spring of 2021, I had an internship with Butterfly Wonderland, where I worked in their conservatory and learned about the ecological relationship between butterflies and plants. As part of my internship, I encouraged guests to learn more about gardening for pollinators. That experience inspired me to complete a creative project in which I would design a butterfly garden of my own that would highlight wildlife benefits and be accessible to people like myself, who do not have their own gardens and don’t have hundreds of dollars to spend on gardening supplies. In collaboration with Dr. Gwen Iacona and Liz Makings (director and second committee member respectively), I planted accessible gardens. By “accessible”, I mean that the gardens were affordable (less than $100 total), included free/upcycled materials wherever possible, and are easily replicable. For my project, I made ‘prototypes’ of the gardens by using freely available seeds and soil sources, germinating those seeds in the ASU Greenhouses, and documenting my process so that it could be shared. Freely available seeds and other materials came from a variety of places including the ASU seed library, local Free Little Libraries, donations, as well as purchases from on campus fundraisers. The germination and growth of seeds in the ASU greenhouse took place over the course of several months in the fall and winter. That documentation has taken on several forms, including an informational pamphlet about wildlife gardening and flyers specific to locally available plant seeds. I find this to be very important because my end goal was to create something that other students or people in our community can use in a practical way. I wanted to create something that will bring gardening into the homes of people who didn’t think they were able to participate in it.
ContributorsBernat, Isabella (Author) / Iacona, Gwen (Thesis director) / Makings, Elizabeth (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor)
Created2022-05
Description

The status of Earth’s diversity is deteriorating quickly which will continue to impact humans’ way of life, as well as every other living creature, in all regions of the world. However, there are organizations taking action to protect biodiversity on our planet. The Convention on Biological Diversity (CBD) is one

The status of Earth’s diversity is deteriorating quickly which will continue to impact humans’ way of life, as well as every other living creature, in all regions of the world. However, there are organizations taking action to protect biodiversity on our planet. The Convention on Biological Diversity (CBD) is one of those organizations and includes 196 signatories from around the world who are committed to strategies to preserve their biodiversity (Secretariat). Indeed, 98% of the parties which have participated in the Convention on Biological Diversity (CBD) have created national biodiversity strategies (NBS) and action plans (NBSAPs) (Secretariat). Yet, there are still countries that have yet to partake in these efforts. America continues to hold out against ratifying the CBD and remains the only developed country without a National Biodiversity Strategy. As an NBS for the U.S. is under consideration, my goal is to understand what works from previous plans. In particular, I focus on stakeholder engagement in Conservation Biodiversity Action Plans. Stakeholder engagement is important because, without it, there may be insufficient levels of integration of the action plans, which can lead to the failure of the CBDs conservation efforts. To address this question, I analyze the 193 strategies created for countries across the globe. My review describes the ways that stakeholders are engaged in National Biodiversity Strategies for CBD member countries. All plans mention some form of engagement. The most common types mentioned are ‘Education’, ‘Communication’, and ‘Training’. Examining the plans further reveals that most forms of engagement often are just mentioned and not completed. Close to 58% of the engagement forms are only completed about 50% of the time. Exceptions are surveys, interviews, and workshops, which are each completed in over 70% of plans that mention them. I then use this information to provide practical recommendations for creating an effective NBSAP for the United States.

ContributorsOlofsson, Elisa (Author) / Gerber, Leah (Thesis director) / Kroetz, Kailin (Committee member) / Sterner, Beckett (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-12
Description
This research dives into the media’s influence, population tracking, new conservation methods, and previous studies to support the thesis that creating a positive public perception of the animals will help reduce shark finning and overfishing. Provisions and solutions provide inspiration for what we can do to reduce the overfishing and

This research dives into the media’s influence, population tracking, new conservation methods, and previous studies to support the thesis that creating a positive public perception of the animals will help reduce shark finning and overfishing. Provisions and solutions provide inspiration for what we can do to reduce the overfishing and finning of sharks.
ContributorsMinhinnick, Tess (Author) / Chew, Matthew (Thesis director) / Lyon, Cassandra (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2023-12
Description
Wound healing is a complex tissue response that requires a coordinated interplay of multiple cells in orchestrated biological processes to restore the skin's barrier function post-injury. Proteolytic enzymes, in particular matrix metalloproteinases (MMPs), contribute to all phases of the healing process by regulating immune cell influx, clearing out the extracellular

Wound healing is a complex tissue response that requires a coordinated interplay of multiple cells in orchestrated biological processes to restore the skin's barrier function post-injury. Proteolytic enzymes, in particular matrix metalloproteinases (MMPs), contribute to all phases of the healing process by regulating immune cell influx, clearing out the extracellular matrix (ECM), and remodeling scar tissue. As a result of these various functions in the healing of skin wounds, uncontrolled activities of MMPs are associated with impaired wound healing. The MMP gene family consists of a highly conserved set of genes. Deleterious mutations in MMP genes cause developmental phenotypes that affect the heart, skeleton, and immune system response. The availability of contiguous draft genomes of non-model organisms enables the study of gene families through analysis of synteny and sequence identity. My project is aimed at conducting a comparative genomic analysis of the MMP gene family from the genomes of 29 tetrapod species—with an emphasis on reptiles. Results regarding the similarities and differences among MMP protein sequences can be further investigated to shed light on the causes which give rise to various adaptive mutations for specific species groups.
ContributorsYu, Alexander (Author) / Kusumi, Kenro (Thesis director) / Dolby, Greer (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-12
Description

Black-footed ferrets have become one of the most popular conservation success stories because of the miraculous rediscovery of the species after being declared extinct and the growing population today. The stability of the species is still highly variable as the ferrets are threatened by disease, habitat fragmentation, human infringement, and

Black-footed ferrets have become one of the most popular conservation success stories because of the miraculous rediscovery of the species after being declared extinct and the growing population today. The stability of the species is still highly variable as the ferrets are threatened by disease, habitat fragmentation, human infringement, and the extermination of their main prey item the prairie dog. The complexity of the issue arises from negative public perceptions of prairie dogs leading to less citizen support for protection which in turn undermines progress in black-footed ferret conservation. General issues with the bureaucracy of conservation helps to delay a formal protection of species at risk which would be especially important for species that are actively being removed or exterminated by humans like the prairie dog. Careful analysis of the black-footed ferret and the prairie dog through the lenses of their natural histories, conservation histories, and modern conservation methods suggest that the public’s opinion and support is the greatest tool for the protection of species at risk because of the complexity of conservation and the rallying bureaucratic motion.

ContributorsMarek, Aislinn (Author) / Taylor, Jesse (Thesis director) / Shaffer, Zachary (Committee member) / Barrett, The Honors College (Contributor) / School of Geographical Sciences and Urban Planning (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

Prairie dogs were once abundant across the plains and grasslands of the Western half of the United States. Four of the five subspecies are found in the United States and have lost 98% of their historical abundance since 1870 due to extermination campaigns, habitat loss, and plague. This species is

Prairie dogs were once abundant across the plains and grasslands of the Western half of the United States. Four of the five subspecies are found in the United States and have lost 98% of their historical abundance since 1870 due to extermination campaigns, habitat loss, and plague. This species is threatened by extinction and already extirpated across most of its range and yet given very little federal or state protection, except for the Utah prairie dog. This leaves most conservation efforts to grassroots and non-profit conservation organizations. This paper looks at the framework used by conservation organizations within conservation campaigns to communicate the need for prairie dog conservation efforts. Thirty-six organizations were found and six frames were identified. The most common frames emphasized prairie dogs’ role as a keystone species and addressed concerns surrounding cattle ranching and prairie dogs and plague transmission. Other frames were used occasionally and showcase underutilization of a wider variety of targeted frames. This paper is the first of its kind to analyze how prairie dog conservation is being communicated through framing theory. This field is under-researched and has the potential to grow and be helpful to future campaigns as they develop communication strategies and create partnerships with other like-minded organizations.

ContributorsOrtiz, Elizabeth (Author) / Lee, Nicole (Thesis director) / Ball, Becky (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

The climate conversation is growing more important and necessary than ever. The media has a way of promoting a "doom and gloom" sentiment over conservation efforts and what the public has the power to do in terms of making a change. Now due to the effects of COVID-19 on the

The climate conversation is growing more important and necessary than ever. The media has a way of promoting a "doom and gloom" sentiment over conservation efforts and what the public has the power to do in terms of making a change. Now due to the effects of COVID-19 on the population's attention spans and memories, there is a need for a way to communicate climate science effectively and to encourage those who feel discouraged by climate change to find their inner power. The answer lies in photography. Making science accessible and intriguing through the art of photography is what can get people more interested and empowered to fight against climate change and alter their attitudes towards environmentalism. This thesis explains psychological research and the reasons why people feel helpless in terms of our global future. In then dives into human subjects research conducted on ASU's campus and how the survey results argue in favor of the paper's hypothesis. Additionally, ways to get involved and reasons why we need to remain hopeful are discussed.

ContributorsGorlick, Vanessa (Author) / Hall, Sharon (Thesis director) / Makings, Elizabeth (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / The Sidney Poitier New American Film School (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2023-05
Description

Invasive species are non-native plants or animals that harm the environment, economy, and even human health. These species are introduced to new environments where they have no natural predators or competitors to keep them in check. As a result, they grow and reproduce quickly, outcompeting and displacing native species. Invasive

Invasive species are non-native plants or animals that harm the environment, economy, and even human health. These species are introduced to new environments where they have no natural predators or competitors to keep them in check. As a result, they grow and reproduce quickly, outcompeting and displacing native species. Invasive species can also damage crops, infrastructure, and property, leading to significant economic losses. Moreover, some invasive species can carry diseases that can affect human health. As the leading cause of biodiversity loss according to the IUCN Red List, controlling and preventing the spread of invasive species is critical to protecting biodiversity and maintaining a healthy environment.

ContributorsTullo, Elizabeth (Author) / Sanft, Alfred (Thesis director) / Heywood, William (Committee member) / Fehler, Michelle (Committee member) / Barrett, The Honors College (Contributor) / The Design School (Contributor) / School of Life Sciences (Contributor)
Created2023-05