Filtering by
- All Subjects: conservation
- All Subjects: Evolution
- Creators: School of Earth and Space Exploration
My research is focused on the people of Turkana, a human pastoral population inhabiting Northwest Kenya. The people of Turkana are Nilotic people that are native to the Turkana district. There are currently no conclusive studies done on evidence for genetic lactase persistence in Turkana. Therefore, my research will be on the evolution of lactase persistence in the people of Turkana. The goal of this project is to investigate the evolutionary history of two genes with known involvement in lactase persistence, LCT and MCM6, in the Turkana. Variants in these genes have previously been identified to result in the ability to digest lactose post-weaning age. Furthermore, an additional study found that a closely related population to the Turkana, the Massai, showed stronger signals of recent selection for lactase persistence than Europeans in these genes. My goal is to characterize known variants associated with lactase persistence by calculating their allele frequencies in the Turkana and conduct selection scans to determine if LCT/MCM6 show signatures of positive selection. In doing this, we conducted a pilot study consisting of 10 female Turkana individuals and 10 females from four different populations from the 1000 genomes project namely: the Yoruba in Ibadan, Nigeria (YRI); Luhya in Webuye, Kenya; Utah Residents with Northern and Western European Ancestry (CEU); and the Southern Han Chinese. The allele frequency calculation suggested that the CEU (Utah Residents with Northern and Western European Ancestry) population had a higher lactase persistence associated allele frequency than all the other populations analyzed here, including the Turkana population. Our Tajima’s D calculations and analysis suggested that both the Turkana population and the four haplotype map populations shows signatures of positive selection in the same region. The iHS selection scans we conducted to detect signatures of positive selection on all five populations showed that the Southern Han Chinese (CHS), the LWK (Luhya in Webuye, Kenya) and the YRI (Yoruba in Ibadan, Nigeria) populations had stronger signatures of positive selection than the Turkana population. The LWK (Luhya in Webuye, Kenya) and the YRI (Yoruba in Ibadan, Nigeria) populations showed the strongest signatures of positive selection in this region. This project serves as a first step in the investigation of lactase persistence in the Turkana population and its evolution over time.
This project was an exploratory take on outreach in the life sciences - looking into the existing literature and practices and formulating a proof of concept for future outreach with synthesizes my findings. The research culminated in the creation of an insect guide for the novice observer, which reads as a modern take on the dichotomous key and allows amateur insect observers to develop some skills of identification with relatively little entomological knowledge.
The Arizona Board of Education decides the science curricula for students K-6. The standards lack an in depth knowledge of marine life, marine science, ocean conservation, and more related topics. Through interviews with teachers, faculty, and research on ocean literacy and coral reefs, My Coral Reef Booklet assembles various learning activities to cater to students from a variety of education, financial and impairment backgrounds. My Coral Reef Booklet addresses coral reef basics and how students can play their part in coral reef conservation despite their location.