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Previous findings from our lab have demonstrated that nicotine and social reward have synergistic effects when experienced together versus when experienced separately. The purpose of this experiment is to understand the neural mechanisms underlying this synergistic effect by quantifying Fos protein, a marker for neural activation, in various brain regions.

Previous findings from our lab have demonstrated that nicotine and social reward have synergistic effects when experienced together versus when experienced separately. The purpose of this experiment is to understand the neural mechanisms underlying this synergistic effect by quantifying Fos protein, a marker for neural activation, in various brain regions. We utilized the conditioning place preference (CPP) model to assess reward. Four groups of adolescent male rats (n=120) were given either nicotine (Nic) (0.1 mg/kg/mL) or saline (Sal) and were placed in the CPP apparatus either with a social partner (Soc) or alone (Iso). Thus, groups were: 1.)Sal+Iso, 2).Sal+Soc, 3).Nic+Iso, 4).Nic+Soc. Brains of some the rats (n=40) were collected for Fos staining 90 minutes after the last conditioning session to obtain Fos data in response to direct exposure to the stimuli. The following regions were analyzed for Fos expression: central amygdala (CeA), medial amygdala (MeA), basolateral amygdala (BLA), nucleus accumbens core (NAcCore), and nucleus accumbens shell (NAcShell). Place preference changes occurred in socially-conditioned groups reflecting social reward and in nicotine-conditioned groups reflecting nicotine reward. As expected, the Sal+Iso control group failed to display a preference change. Fos data revealed a significant increase in Fos expression in the CeA, MeA, NAcCore and NAcShell for socially-conditioned animals and a significant decrease in the NAcCore for nicotine-conditioned groups. Experiencing both social and nicotine rewards together appeared to produce greater activation in the BLA. However, there was an increase in Fos expression in the negative control group relative to Nic+Iso group. The results of CPP suggest that social, nicotine and their combination are rewarding. The combination of the nicotine and social reward could have been more rewarding than social and nicotine separately, but the test was not sensitive to reward magnitude. The increase in Fos expression in the negative control group in the BLA could be due to isolation stress. Overall, these results suggest that these brain regions had greater activation to social reward.
ContributorsGoenaga, Julianna Gloria (Author) / Neisewander, Janet (Thesis director) / Orchinik, Miles (Committee member) / Olive, Michael (Committee member) / Barrett, The Honors College (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / School of Life Sciences (Contributor)
Created2013-05
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Description

Brundtland’s definition of sustainability is the ability to “meet the needs of the present without compromising the ability of future generations to meet their needs” (IISD, 2021). But what if there are no future generations? Social sustainability, the sector of sustainability that foregrounds the well-being and livelihoods of people (and

Brundtland’s definition of sustainability is the ability to “meet the needs of the present without compromising the ability of future generations to meet their needs” (IISD, 2021). But what if there are no future generations? Social sustainability, the sector of sustainability that foregrounds the well-being and livelihoods of people (and thereby continuation of humanity), is included in definitions within the sustainability field, but less developed in sustainability practice. In an effort to bridge this gap of knowledge, 14 U.S. cities and over 100 sustainability policies were analyzed for their social sustainability performance. An eight-item analytical framework that deals with differing areas of social equity guided the analysis. Results found that most cities’ sustainability departments fell short of truly addressing social sustainability concerns. Out of the eight items, the most frequently addressed were housing security and racial and gender equality whereas few, if any, cities addressed the more specific social concerns of immigration, technology and media, or arts/cultural preservation. Future research is recommended to gain a better understanding of the ways existing cities can improve in this area.

ContributorsTam, Joey (Co-author) / Weekes, Daniel (Co-author) / Brian, Jennifer (Thesis director) / Keeler, Lauren (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The marmoset monkey (Callithrix jacchus) is a new-world primate species native to South America rainforests. Because they rely on vocal communication to navigate and survive, marmosets have evolved as a promising primate model to study vocal production, perception, cognition, and social interactions. The purpose of this project is to provide

The marmoset monkey (Callithrix jacchus) is a new-world primate species native to South America rainforests. Because they rely on vocal communication to navigate and survive, marmosets have evolved as a promising primate model to study vocal production, perception, cognition, and social interactions. The purpose of this project is to provide an initial assessment on the vocal repertoire of a marmoset colony raised at Arizona State University and call types they use in different social conditions. The vocal production of a colony of 16 marmoset monkeys was recorded in 3 different conditions with three repeats of each condition. The positive condition involves a caretaker distributing food, the negative condition involves an experimenter taking a marmoset out of his cage to a different room, and the control condition is the normal state of the colony with no human interference. A total of 5396 samples of calls were collected during a total of 256 minutes of audio recordings. Call types were analyzed in semi-automated computer programs developed in the Laboratory of Auditory Computation and Neurophysiology. A total of 5 major call types were identified and their variants in different social conditions were analyzed. The results showed that the total number of calls and the type of calls made differed in the three social conditions, suggesting that monkey vocalization signals and depends on the social context.
ContributorsFernandez, Jessmin Natalie (Author) / Zhou, Yi (Thesis director) / Berisha, Visar (Committee member) / School of International Letters and Cultures (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
An individual’s reputation can be beneficial or detrimental to their exchanges with others,
and these exchanges may be critical for achieving evolutionary goals, such as reproduction.
Depending on their reputation, an individual may or may not gain access to resources in order to
achieve their evolutionary goals. Reputation is typically described as being

An individual’s reputation can be beneficial or detrimental to their exchanges with others,
and these exchanges may be critical for achieving evolutionary goals, such as reproduction.
Depending on their reputation, an individual may or may not gain access to resources in order to
achieve their evolutionary goals. Reputation is typically described as being “positive” and
“negative,” but the current study aimed to identify potential nuances to reputations beyond the
traditional dichotomy. It was hypothesized that different types of reputations (such as “friendly”,
“dishonest”, and “aggressive”) would group together in categories beyond “positive” and
“negative.” Additionally, individuals with different life history strategies might find different
reputations important, because the reputations they find most important may help them get the
kinds of resources they need to attain their specific evolutionary goals. Therefore, it was also
predicted that the importance individuals place on different types of reputations would vary as a
function of life history strategy. Exploratory factor analysis identified a five factor structure for
reputations. Individuals also placed varying levels of importance on different types of
reputations, and found some reputations more important than others depending on their life
history strategy. This study demonstrates that reputational information is more nuanced than
previously thought and future research should consider that there may be more than just
“positive” and “negative” reputations in social interactions.
ContributorsPatterson, Danielle Nicole (Author) / Aktipis, Athena (Thesis director) / Corbin, William (Committee member) / West, Stephen G. (Committee member) / Ayers, Jessica D. (Committee member) / Department of Psychology (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12