This thesis project is part of the W.P. Carey Founders Lab, a collaborative entrepreneurship track that gives students the opportunity to create a start-up business based on a list of given problems or technologies. The technology selected utilized a piece of NASA technology (U.S. patent application 20200193857) that combines mixed, virtual, and augmented reality (MR, VR, and AR) with biofeedback metrics to help athletes get in the zone. The goal is to use the technology during practice so athletes can be better prepared to combat performance anxiety during high-pressure situations. The NASA patent states that if the user’s brain activity, sweat, or heartbeat indicate that they are stressed while completing the activity, the device will make it more difficult for the athlete to complete their task. ITZ’s device increases the difficulty of hitting a target with a ball by obscuring the vision with augmented reality graphics. The visual obstacles will subside if the user’s brain activity metrics indicate that they have become more calm or focused. Due to circumstances outside of the team's control, a prototype was unable to be obtained, and the idea was based on the patent and supporting documentation provided after a meeting with NASA.

Diabetes affects millions of people globally and can lead to other severe health complications when undiagnosed or not properly managed. The incidence of diabetes has rapidly increased over the past several years, however, not all individuals have access to affordable or convenient healthcare. We hypothesize that wastewater-based epidemiology (WBE) has the potential to assess community health status by analyzing biomarkers indicative of human health and disease, including diabetes. Used in tandem with current methods, monitoring indicators of diabetes in community wastewater could provide a comprehensive assessment tool for disease prevalence in large and small populations. Specifically, the proposed targeted biomarker evaluated in this study to indicate population-wide diabetes prevalence was 8-hydroxy-2’- deoxyguanosine (8-OHdG). This work combines a rigorous literature review and initial laboratory studies to explore the possibility of diabetes monitoring at the community level using WBE. Here, 24-hour composite wastewater samples were collected from within two wastewater sub-catchments of Greater Tempe, AZ. Overall goals of this study were to: i) Determine the feasibility to detect endogenous markers of diabetes in community wastewater; ii) Assess the potential impact of confounding factors, such as smoking, cancer, and atherosclerosis, through a literature analysis; and iii) Evaluate the socioeconomic status and demographics of the study population. Preliminary results of the experiments suggest this methodology to be feasible, as indicated by the observation of detectable signals of 8-OHdG in community wastewater collected from the sewer infrastructure; however, future work and continued experimentation will be required to address low signal intensity and assay precision and accuracy. Thus, the work presented here provides valuable proof-of-concept data, with detailed information on the method employed and identified opportunities to further determine the relationship between 8-OHdG concentrations in municipal wastewater and diabetes prevalence at the community level.

Diabetes affects millions of people globally and can lead to other severe health complications when undiagnosed or not properly managed. The incidence of diabetes has rapidly increased over the past several years, however, not all individuals have access to affordable or convenient healthcare. We hypothesize that wastewater-based epidemiology (WBE) has the potential to assess community health status by analyzing biomarkers indicative of human health and disease, including diabetes. Used in tandem with current methods, monitoring indicators of diabetes in community wastewater could provide a comprehensive assessment tool for disease prevalence in large and small populations. Specifically, the proposed targeted biomarker evaluated in this study to indicate population-wide diabetes prevalence was 8-hydroxy-2’-deoxyguanosine (8-OHdG). This work combines a rigorous literature review and initial laboratory studies to explore the possibility of diabetes monitoring at the community level using WBE. Here, 24-hour composite wastewater samples were collected from within two wastewater sub-catchments of Greater Tempe, AZ. Overall goals of this study were to: i) Determine the feasibility to detect endogenous markers of diabetes in community wastewater; ii) Assess the potential impact of confounding factors, such as smoking, cancer, and atherosclerosis, through a literature analysis; and iii) Evaluate the socioeconomic status and demographics of the study population. Preliminary results of the experiments suggest this methodology to be feasible, as indicated by the observation of detectable signals of 8-OHdG in community wastewater collected from the sewer infrastructure; however, future work and continued experimentation will be required to address low signal intensity and assay precision and accuracy. Thus, the work presented here provides valuable proof-of-concept data, with detailed information on the method employed and identified opportunities to further determine the relationship between 8-OHdG concentrations in municipal wastewater and diabetes prevalence at the community level.

A notable dilemma in the educational systems of current year is the lack of diversity in the faculty, administration, and curriculums. Diversity in education is colloquially understood to instill benefits in students that include development of sophisticated communication skills and heightened motivation, which may in turn have measurable benefits on health. In an effort to articulate the impact of introducing greater variegation into these systems and vocalize recommendations toward incorporating diversity into existing educational systems, the history of minority groups in schooling systems was analyzed, as were common health concerns for these communities. To this end, local students from Arizona State University were surveyed about their perceptions on diverse populations within their educational system. Moreover, these groups were also polled about how the messaging they receive about health and diversity may impact self-perceptions about their own health, as well as how applicable that messaging is with their own experiences.

In response to the Bosnian and Rwandan genocides of the 1990’s, the United Nations created the Responsibility to Protect (R2P) doctrine as part of its 2005 World Summit Outcome document. The goal of R2P is to promote the idea that the international community should act to protect populations from mass atrocity crimes (genocide, crimes against humanity, war crimes, and ethnic cleansing) in the case a State fails to meet their responsibility. This report seeks to examine the Responsibility to Protect principle and see how its concepts are perceived and implemented in the private sector, given the sector’s significant influence in the world today. Using R2P as a frame of reference, I explored the concept that private sector organizations, through their actions and operations, have a responsibility to not profit from or enable systems that perpetuate mass atrocity crimes against populations. This was done through an analysis of private sector firms, regulatory frameworks, industry norms, organization initiatives, and perspectives of actors engaging with the subject matter, in addition to a modern case study regarding the experience of Uighurs and Turkic Muslims in Xinjiang, China. The scope of this project was focused on select American companies that are multinational publicly traded companies with a market capitalization of over $200 billion. This report is meant to serve as a guide for into the concepts of R2P in the private sector and provides access to resources for further exploration.

This Thesis Project was completed to gain experience in how to create a viable business concept pitch as part of the start-up venture process. During the course of the project the company name–“Vibes Clothing”–and business proposition–“To provide fashion-minded athletic individuals with stylish, versatile, and fully functional luminescent clothing.”–were conceived. However, to further develop the company idea into a viable business concept, market analysis, and customer research were conducted. The identified market conditions and customer desires were then utilized to refine Vibes Clothing's logo, brand, and product. These business and design considerations were then strategically implemented in a men’s-model luminescent clothing prototype. As a further part of ‘the creation of a business concept pitch’–typical of one given at a pitch competition or to a group of investors–a business executive summary and funding pitch presentation were also created. Ultimately, this Thesis Project successfully culminated as a formal business concept pitch; wherein a functional display prototype, business executive summary, and funding pitch presentation were all developed.