Matching Items (258)
Filtering by
- All Subjects: Business
- Member of: Barrett, The Honors College Thesis/Creative Project Collection
- Resource Type: Text
Description
Medicine is evolving at an accelerating rate. The needs of the future in medicine are different than the needs of today. With many possible outcomes for the future of medicine, researchers and physicians have tried to predict the future for particular fields. As new healthcare workers enter the medical field, their training must be tailored to provide the best education to prepare healthcare workers for their careers. Therefore, it is imperative to take a closer look into the future in order to better decide how to train doctors, nurses, PA’s, etc. effectively to provide the best care possible.
ContributorsHewlett, Jessica Lynn (Author) / Sklar, David (Thesis director) / Lindor, Keith (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Asthma is one of the most common chronic conditions in the United States, being diagnosed in over 20 million Americans. The condition is even more common among young children, and their academic performance and ability to attend school can be negatively impacted by poorly-managed asthma. Digital therapeutics are therapeutic interventions driven by high quality software programs to prevent, manage, or treat a medical disorder or disease. Technology in the healthcare space is rapidly improving, and smart devices are becoming more common everyday. How can digital therapeutics and evolving technology be implemented to make life easier for those that suffer from asthma and chronic obstructive pulmonary disease? My research seeks to answer the overarching question: How might we improve the day-to-day experience of children with asthma? Airie is a system of devices and products that educate both asthmatic children and their parents about the condition, facilitate self-monitoring and asthma management skills, and improve overall quality of life.
ContributorsChen, Jane Jialin (Author) / Shin, Dosun (Thesis director) / Feil, Magnus (Committee member) / The Design School (Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Populations in the United States and globally struggle to receive equal and affordable access to healthcare, this is no secret. However there are several minority and underprivileged groups within the population that experience disproportionate quality of healthcare when compared to their cis-gendered heterosexual counterparts.
Individuals that align and identify themselves as part of the Lesbian, Gay, Bisexual, Transgender, Queer/Questioning (LGBTQ+) Community, often face discrimination and bias from within the healthcare system that prevent them from receiving adequate patient knowledge, tailored and beneficial healthcare, as well as social support when seeking treatment for conditions that may at times, be more persistent within the community. Examples of these holes within the healthcare system include a lack of culturally competent and appropriate care for those in the community, access to affordable treatments, and other unique health needs.
Consequently, as a minority group these members face social and environmental factors that contribute to their overall wellbeing and health, and therefore training and education need to be implemented for future and current healthcare providers to assess, recognize and acknowledge these varying factors and how they contribute to a patient’s overall wellbeing.
Individuals that align and identify themselves as part of the Lesbian, Gay, Bisexual, Transgender, Queer/Questioning (LGBTQ+) Community, often face discrimination and bias from within the healthcare system that prevent them from receiving adequate patient knowledge, tailored and beneficial healthcare, as well as social support when seeking treatment for conditions that may at times, be more persistent within the community. Examples of these holes within the healthcare system include a lack of culturally competent and appropriate care for those in the community, access to affordable treatments, and other unique health needs.
Consequently, as a minority group these members face social and environmental factors that contribute to their overall wellbeing and health, and therefore training and education need to be implemented for future and current healthcare providers to assess, recognize and acknowledge these varying factors and how they contribute to a patient’s overall wellbeing.
ContributorsRandell, Arianna Nicole (Author) / Kizer, Elizabeth (Thesis director) / Don, Rachael (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
There is an enormous unmet need for services, education, and outreach to improve women’s breast health. Healthcare systems and insurance systems vary widely around the world, and this may play an important role in understanding variability in women’s breast health knowledge and behavior globally. The goal of this study is to determine how varying healthcare systems in three countries (Japan, Paraguay, US) affect a woman’s likelihood of seeing a physician in regard to their breasts. For example, Japan is a clear example of a region that provides universal health insurance to its citizens. The government takes responsibility in giving accessible and equitable healthcare to its entire population (Zhang & Oyama, 2016). On the other hand, a country such as Paraguay is composed of both public and private sectors. In order for citizens to gain insurance, one would have to either be formally employed or choose to pay out-of-pocket for hospital visits (“Paraguay”, 2017). A country such as the United States does not have universal health insurance. However, it does have a mix of public and private sectors, meaning there is little to no coverage for its citizens. To accommodate for this, the United States came up with the Affordable Care Act, which extends coverage to the uninsured. Although the United States might be a country that spends more on healthcare than any other nation, there are residents that still lack healthcare (De Lew, Greenberg & Kinchen, 1992). This study, then, compares women’s breast health knowledge and behavior in Japan, Paraguay, and the US. Other variables, which are also considered in this study, that might affect this include wealth level, education, having general awareness of breast cancer, having regular health checks, and having some breast education. Using statistical analysis of breast check rates of women in Japan, Paraguay, and the United States, this research found that women sampled in Asunción, Paraguay check their breasts more often than either women sampled from Scottsdale, U.S. or Osaka, Japan. It was also found that women sampled from Paraguay were more confident in detecting changes in their breast compared to women sampled from the Japan or the US. Finally, it was noted that women sampled from Japan were least likely to partake in seeing a doctor in concern of changes in their breasts compared to women sampled from the other two research locations. These findings have relevance for the implementation of advocacy and public education about breast health.
ContributorsKumar, Navneet Surjit (Co-author) / Kumar, Navneet (Co-author) / Wutich, Amber (Thesis director) / Brewis, Alexandra (Committee member) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The retinoid-X receptor (RXR) can form heterodimers with both the retinoic-acid
receptor (RAR) and vitamin D receptor (VDR). The RXR/RAR dimer is activated by ligand all
trans retinoic acid (ATRA), which culminates in gut-specific effector T cell migration. Similarly,
the VDR/RXR dimer binds 1,25(OH)2D3 to cause skin-specific effector T cell migration.
Targeted migration is a potent addition to current vaccines, as it would induce activated T cell
trafficking to appropriate areas of the immune system and ensure optimal stimulation (40).
ATRA, while in use clinically, is limited by toxicity and chemical instability. Rexinoids
are stable, synthetically developed ligands specific for the RXR. We have previously shown that
select rexinoids can enhance upregulation of gut tropic CCR9 receptors on effector T cells.
However, it is important to establish whether these cells can actually migrate, to show the
potential of rexinoids as vaccine adjuvants that can cause gut specific T cell migration.
Additionally, since the RXR is a major contributor to VDR-mediated transcription and
epidermotropism (15), it is worth investigating whether these compounds can also function as
adjuvants that promote migration by increasing expression of skin tropic CCR10 receptors on T
cells.
Prior experiments have demonstrated that select rexinoids can induce gut tropic migration
of CD8+ T cells in an in vitro assay and are comparable in effectiveness to ATRA (7). The effect
of rexinoids on CD4+ T cells is unknown however, so the aim of this project was to determine if
rexinoids can cause gut tropic migration in CD4+ T cells to a similar extent. A secondary aim
was to investigate whether varying concentrations in 1,25-Dihydroxyvitamin D3 can be linked to
increasing CCR10 upregulation on Jurkat CD4+ T cells, with the future aim to combine 1,25
Dihydroxyvitamin D3 with rexinoids.
These hypotheses were tested using murine splenocytes for the migration experiment, and
human Jurkat CD4+ T cells for the vitamin D experiment. Migration was assessed using a
Transwell chemotaxis assay. Our findings support the potential of rexinoids as compounds
capable of causing gut-tropic migration in murine CD4+ T cells in vitro, like ATRA. We did not
observe conclusive evidence that vitamin D3 causes upregulated CCR10 expression, but this
experiment must be repeated with a human primary T cell line.
receptor (RAR) and vitamin D receptor (VDR). The RXR/RAR dimer is activated by ligand all
trans retinoic acid (ATRA), which culminates in gut-specific effector T cell migration. Similarly,
the VDR/RXR dimer binds 1,25(OH)2D3 to cause skin-specific effector T cell migration.
Targeted migration is a potent addition to current vaccines, as it would induce activated T cell
trafficking to appropriate areas of the immune system and ensure optimal stimulation (40).
ATRA, while in use clinically, is limited by toxicity and chemical instability. Rexinoids
are stable, synthetically developed ligands specific for the RXR. We have previously shown that
select rexinoids can enhance upregulation of gut tropic CCR9 receptors on effector T cells.
However, it is important to establish whether these cells can actually migrate, to show the
potential of rexinoids as vaccine adjuvants that can cause gut specific T cell migration.
Additionally, since the RXR is a major contributor to VDR-mediated transcription and
epidermotropism (15), it is worth investigating whether these compounds can also function as
adjuvants that promote migration by increasing expression of skin tropic CCR10 receptors on T
cells.
Prior experiments have demonstrated that select rexinoids can induce gut tropic migration
of CD8+ T cells in an in vitro assay and are comparable in effectiveness to ATRA (7). The effect
of rexinoids on CD4+ T cells is unknown however, so the aim of this project was to determine if
rexinoids can cause gut tropic migration in CD4+ T cells to a similar extent. A secondary aim
was to investigate whether varying concentrations in 1,25-Dihydroxyvitamin D3 can be linked to
increasing CCR10 upregulation on Jurkat CD4+ T cells, with the future aim to combine 1,25
Dihydroxyvitamin D3 with rexinoids.
These hypotheses were tested using murine splenocytes for the migration experiment, and
human Jurkat CD4+ T cells for the vitamin D experiment. Migration was assessed using a
Transwell chemotaxis assay. Our findings support the potential of rexinoids as compounds
capable of causing gut-tropic migration in murine CD4+ T cells in vitro, like ATRA. We did not
observe conclusive evidence that vitamin D3 causes upregulated CCR10 expression, but this
experiment must be repeated with a human primary T cell line.
ContributorsDebray, Hannah Zara (Co-author) / Debray, Hannah (Co-author) / Blattman, Joseph (Thesis director) / Jurutka, Peter (Committee member) / Manhas, Kavita (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This project analyzes the large array of managerial leadership research in congruence with the wide field of workplace communication to attempt to determine the importance of refining communication channels between managers and employees as well as articulate the core competencies a manager should exhibit when practicing exemplary communication in their respective work environment. The preliminary sections of this thesis will establish the currently existing foundations utilized and narrow the wide range of research available to applicable information regarding positive workplace communication, influencing factors in a feedback loop from the employee’s perspective, as well as leadership aspects and actions a manager can alter or initiate to improve their workplace’s environment through communicational refinement. This research is supplemented with a survey that was administered to Arizona State University student leaders who were involved in coordinating the Regional Business Conference on the Polytechnic campus. The survey data is designed to either confirm or contradict the findings of the literature. The objective of this project is to synthesize an overview of a manager’s responsibilities and recommend actions to tailor and improve workplace communication
ContributorsWhelan-Gonzales, Luke Andrew (Author) / Schmitz, Troy (Thesis director) / Pegg, TJ (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
As of March 2020, there were over 112,400 patients actively waiting on the United States national organ transplant waitlist with only about 3,300 donors1. Although transplantation is an effective treatment for end-stage organ failure, the access to a procedure will vary depending on national regulations, cost of health care, extensive screening processes, and the availability of organs2. Organ shortage is a worldwide problem, and the growing insufficiency has resulted patients becoming too for ill or dying while waiting3. Due to the varying wait times and costs of procedures, some patients have begun to outsource their own transplantation through international transactions, also known as transplant tourism2. The 2004 World Health Assembly resolution recognized these trades as a significant health policy issue, while also acknowledging the inability of national health care systems to meet the needs of patients4. To address this issue, a proposal will be made such that all live kidney and liver donors will be compensated $22,500 and $12,150 respectively through a cost-neutral scheme based on annual healthcare expenditures per organ that would be eliminated by a transplant. With this proposal, it is suggested that the organ transplant waitlist would not only be significantly reduced, but potentially eliminated, and the crisis of organ shortage would be defeated.
ContributorsMartin, Starla (Author) / Kingsbury, Jeffrey (Thesis director) / Edmonds, Hallie (Committee member) / School of Molecular Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Over the past seven years, the Student Health Outreach for Wellness (SHOW) Community Initiative has served vulnerable populations in Maricopa County through a volunteer workforce of providers, graduate health professional students, and undergraduates from all three of Arizona’s public universities. With an interprofessional volunteer base, SHOW has managed to transition its health education and screenings from a clinic-based setting to community-based settings. These new clinical outreach programs within SHOW present unique challenges to maintaining the integrity of interprofessional, team-based care, and new evaluative tools are needed to provide feedback for improvement. Now, as a pioneer site for the National Center for Interprofessional Practice and Education, SHOW must continue to conduct internal research to evaluate their innovative model of care. For this project, the four core competency domains for interprofessional collaborative practice were used to outline proposals for the implementation of several new evaluative measures: the Assessment for Collaborative Environments (ACE-15), the Interprofessional Collaborative Competencies Attainment Survey (ICCAS), patient satisfaction surveys, and critical incident reporting. These tools and protocols are necessary to solidify SHOW as a national model for interprofessional education and practice.
ContributorsSmith, Julianna Marie (Author) / Harrell, Susan (Thesis director) / Saewert, Karen (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Often considered to be one of the most promising solutions in the fight against global poverty, “microfinance is a term used to describe financial services, such as loans, savings, insurance and fund transfers to entrepreneurs, small businesses and individuals who lack access to traditional baking services” (Kiva). With hundreds of organizations committed or partially committed to the facilitation of microfinance loans on a domestic and global scale, the way scholarly communities have ultimately decided to view this type of giving is narrow but optimistic. The trends associated with microfinancing show it to have a positive impact on both lenders and borrowers. The goal of this thesis is to bring a level of personal context to these trends with qualitative research from the stories of individuals who have participated in the facilitation of a microloan.
ContributorsOlsen, Hannah (Author) / LaRosa, Julia (Thesis director) / Price, Sandra (Committee member) / School of Community Resources and Development (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this study is to analyze what barriers of care exist within the Senor de los Milagros community in Trujillo, Peru and how these barriers to care can identify shortcomings in the public healthcare system. This study is a collaboration of field research and outside literature. The research conducted was done via structured interviews with 15 participants, all promotoras (mothers of the community) and their husbands in the Senor de los Milagros community of Trujillo, Peru. Summaries and quotes from these interviews were uploaded and quantified to identify common barriers to care derived from socioeconomic and cultural determinants . Although this was on the main focus of the study, observations and conversations with healthcare staff and patients showed that the two most specific barriers found when data was analyzed were the wait times of public sector facilities and quality of care within these facilities. These barriers to care did not stop the promotoras from seeking care at MINSA facilities, but it does pose the questions as to how it affects healthcare-seeking behaviors and if this affects long-term healthcare outcomes.
ContributorsDragon, Jordan Elizabeth (Author) / Maupin, Jonathan (Thesis director) / Marsteller, Sara (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05