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Abstract Ambrofit is a company I founded in February 2014 whose overarching goal is to bridge the gap between science and supplements. This thesis project is as an extension of, and upgrade to, Ambrofit's work. The project begins with a brief discussion of the supplement industry, motivating the problem which

Abstract Ambrofit is a company I founded in February 2014 whose overarching goal is to bridge the gap between science and supplements. This thesis project is as an extension of, and upgrade to, Ambrofit's work. The project begins with a brief discussion of the supplement industry, motivating the problem which myself and Ambrofit are trying to solve. It addresses the shortcomings of the industry, its regulatory history, and the causal factors which create the industry's environment. As the main part of the project, I design and execute a systematic, evidence-based nutritional product formulation process to create an scientifically sound ergogenic aid which can reliably accelerate training adaptations. The methodology starts with a round of exploratory research to discover potential ingredients then systematically analyzes each ingredient in multiple rounds of effectiveness and safety screenings until the final formula can be synthesized. Ergogenics were the focus of this project because Ambrofit's current product is an ergogenic aid, but I will apply this same process to formulate Ambrofit's whole product line in the future. The second arm of the project is a clinical study protocol design - an evidence-based product created from secondary research is a good start, but ultimately, the formula must be validated by direct research. The protocol describes an 8-week study with well-trained subjects which would either support or reject the formula's ability to accelerate anaerobic training adaptations. The project concludes with a discussion and application of Ambrofit's marketing. This part of the project was done with boots-on-the-ground; Ambrofit is already operating commercially, so I was able test marketing ideas live and evaluate their performance.
ContributorsRoper, Jacob William (Author) / Denning, Michael (Thesis director) / Johnston, Carol (Committee member) / Department of Marketing (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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The concept of the Mediterranean Diet was described by Ancel Keys from the Seven Countries study, occurring in the 1960s. Unlike other diets, the Mediterranean Diet is a cultural tradition of nations surrounding the Mediterranean Sea. It involves the healthy pattern of food consumption and physical activity, which developed as

The concept of the Mediterranean Diet was described by Ancel Keys from the Seven Countries study, occurring in the 1960s. Unlike other diets, the Mediterranean Diet is a cultural tradition of nations surrounding the Mediterranean Sea. It involves the healthy pattern of food consumption and physical activity, which developed as an outcome of the locality's available food, other environmental resources, and overall cultural characteristics such as the polychromic time orientation of the Mediterranean nations. The Mediterranean Diet is a lifestyle structured around understanding a locality's natural conditions and resources and sustaining positive relationships between individuals, the community, and the components of their environment. The diet is largely plant based, where daily foods include grains, fruits, vegetables, olive oil, and dairy products. Seafood is eaten several times a week, while other animal products (poultry, meats, eggs) and sweets are eaten less often and in moderation. Alcohol, for those who drink it, is consumed several times a week. Research has shown a variety of health benefits from this diet. These benefits include preventing cardiovascular disease, certain cancers, Type 2 diabetes, Alzheimer's disease, age related macular degeneration of the eyes, kidney disease and osteoporosis. It also has been shown to improve conditions of metabolic syndrome, obesity, and depression. These favorable health outcomes are a result of the beneficial components within the foods commonly eaten. Fruits and vegetables are excellent sources of vitamins and minerals, which are needed to support cellular and overall organismal functioning, and nuts, vegetables, and fish also provide essential fatty acids like omega-3 and omega-6. The unifying component for all regions adhering to the Mediterranean Diet is the use of olive oil. Beyond being a healthy source of fat, it contains numerous chemical components with antioxidant properties. The Mediterranean region is an optimal region for olive tree growth and olive harvest, based on temperature and soil conditions. However, geographic differences, nutrient availability and age of olive trees can impact the quality of olive fruits and olive oil. Furthermore, climate change presents a challenge for sustaining the Mediterranean diet as it adds stress to plants and aquatic life environments. However, the diet shows promise of protecting the environment, as plant-based diets are found to have lower negative environmental impacts. In conclusion, the Mediterranean diet is an interconnected system of relationships that adapts to a locality's community, land, and climate.
ContributorsKaneris, Marianna Irene (Author) / Vitullo, Juliann (Thesis director) / Dal Martello, Chiara (Committee member) / Department of Psychology (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
This study was conducted to observe the effects of vitamin C supplementation upon the expression of sICAM-1 in asthmatic subject. Two groups were created, each with a sample size of 4 subjects. One group was the vitamin C group (VC) and the other was the placebo group (PL). The study

This study was conducted to observe the effects of vitamin C supplementation upon the expression of sICAM-1 in asthmatic subject. Two groups were created, each with a sample size of 4 subjects. One group was the vitamin C group (VC) and the other was the placebo group (PL). The study was analyzed through observing concentrations of biomolecules present within samples of blood plasma and nasal lavages. These included vitamin C, sICAM-1 expression, and histamine. The following P-values calculated from the data collected from this study. The plasma vitamin C screening was p=0.3, and after 18 days of supplementation, p=0.03. For Nasal ICAM p=0.5 at Day 0, p=0.4 at Day 4, and p=0.9 at Day 18. For the Histamine samples p=0.9 at Day 0 and p=0.9 at Day 18. The following P-values calculated from the data collected from both studies. The plasma vitamin C screening was p=0.8, and after 18 days of supplementation, p=0.03. The change of vitamin C at the end of this study and the combined data both had a P-value that was calculated to be lower than 0.05, which meant that this change was significant because it was due to the intervention and not chance. For Nasal ICAM samples p=0.7 at Day 0, p=0.7 at Day 4, and p=1 at Day 18. For the Histamine p=0.7 at Day 0 and p=0.9 at Day 18. This study carries various implications although the study data was unable to show much significance. This was the second study to test this, and as more research is done, and the sample size grows, one will be able to observe whether this really is the mechanism through which vitamin C plays a role in immunological functions.
ContributorsKapadia, Chirag Vinay (Author) / Johnston, Carol (Thesis director) / LaBaer, Joshua (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
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Description

Since 1975, the prevalence of obesity has nearly tripled around the world. In 2016, 39% of adults, or 1.9 billion people, were considered overweight, and 13% of adults, or 650 million people, were considered obese. Furthermore, Cardiovascular disease remains to be the leading cause of death for adults in the

Since 1975, the prevalence of obesity has nearly tripled around the world. In 2016, 39% of adults, or 1.9 billion people, were considered overweight, and 13% of adults, or 650 million people, were considered obese. Furthermore, Cardiovascular disease remains to be the leading cause of death for adults in the United States, with 655,000 people dying from related conditions and consequences each year. Including fiber in one’s dietary regimen has been shown to greatly improve health outcomes in regards to these two areas of health. However, not much literature is available on the effects of corn-based fiber, especially detailing the individual components of the grain itself. The purpose of this preliminary study was to test the differences in influence on both LDL-cholesterol and triglycerides between treatments based on whole-grain corn flour, refined corn flour, and 50% refined corn flour + 50% corn bran derived from whole grain cornmeal (excellent fiber) in healthy overweight (BMI ≥ 25.0 kg/m2) adults (ages 18 - 70) with high LDL cholesterol (LDL ≥ 120mg/dL). 20 participants, ages 18 - 64 (10 males, 10 females) were involved. Data was derived from blood draws taken before and after each of the three treatments as well as before and after each treatment’s wash out periods. A general linear model was used to assess the effect of corn products on circulating concentrations of LDL-cholesterol and triglycerides. From the model, it was found that the whole-grain corn flour and the 50% refined corn flour + 50% corn bran drive from whole grain cornmeal treatments produced a higher, similar benefit in reductions in LDL-cholesterol. However, the whole grain flour, refined flour, and bran-based fiber treatments did not influence the triglyceride levels of the participants throughout this study. Further research is needed to elucidate the effects of these fiber items on cardiometabolic disease markers in the long-term as well as with a larger sample size.

ContributorsLe, Justin (Author) / Whisner, Corrie (Thesis director) / Ortega Santos, Carmen (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

This paper outlines cumulative research on food deserts in relation to college students; namely, that there are communities classified as food deserts because significant numbers of the population lack access to grocery stores selling fresh produce or other goods normally called “healthy.” These areas are often also food swamps, or

This paper outlines cumulative research on food deserts in relation to college students; namely, that there are communities classified as food deserts because significant numbers of the population lack access to grocery stores selling fresh produce or other goods normally called “healthy.” These areas are often also food swamps, or areas with intense access to sugar-dense, high-fat foods. Research as a whole suggests that three, among many, things might primarily drive food insecurity for individuals caught in these food deserts: lack of access to a personal vehicle, low income or prohibitively expensive healthy foods, and personal education or culture (Wright, 2016). College students both fit into the geographical food deserts and are individuals who tend to have a worrying level of food insecurity (Kim, 2018). It is costly to make adjustments to entire environments to rid communities of food desert qualities, and it is not always effective as ending food insecurity or malnutrition; instead, it can be much more effective to focus on individuals within communities and help push cultures into a better direction. This project demonstrates that ASU students are experiencing food dissatisfaction and are in a food desert worthy of attention and action, and that students are motivated to see a solution. The solution that the paper focuses on is a food delivery system of fresh produce and foods for students. 


ContributorsRaghuraman, Vidya (Author) / Gailey, Tim (Co-author) / Hailey, Lauren (Co-author) / Reyes, Marina (Co-author) / Byrne, Jared (Thesis director) / Satpathy, Asish (Committee member) / Balven, Rachel (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of Marketing (Contributor) / The Design School (Contributor)
Created2022-05
Description

Chutneys are a form of Indian condiment that can be made in many different flavors and paired with various foods. However, the availability of chutneys in the United States is very limited and many people have not tried them before. With this observation in mind, we founded A2Z Chutneys, which

Chutneys are a form of Indian condiment that can be made in many different flavors and paired with various foods. However, the availability of chutneys in the United States is very limited and many people have not tried them before. With this observation in mind, we founded A2Z Chutneys, which is a business that aims to distribute a variety of organic and locally produced chutneys. Through the Founders Lab program, A2Z Chutneys was created and research was conducted to justify the viability of our business. We were able to gather and interpret data from potential customers, which allowed us to identify a target market. Additionally, time was spent identifying and creating a variety of authentic and unique chutneys that have proven to be desired. This report demonstrates and outlines the feasibility of A2Z Chutneys in providing unique and desirable flavors to the population.

ContributorsPatel, Javin (Author) / Macha, Sankshay (Co-author) / Byrne, Jared (Thesis director) / Patel, Manish (Committee member) / Pierce, John (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor) / School of Politics and Global Studies (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description
This thesis aims to properly prepare athletes for the significant life changes that will impact them as they transition from college or amateur athletics to professional sports careers. This thesis also identifies the benefits that reap from early education on expectations of learning what to expect at an earlier point

This thesis aims to properly prepare athletes for the significant life changes that will impact them as they transition from college or amateur athletics to professional sports careers. This thesis also identifies the benefits that reap from early education on expectations of learning what to expect at an earlier point in their amateur career. Certain areas are struck as having increasing importance in the transition: financial preparation, mental health and mental strengthening, public relations practice, nutritional needs, and other lifestyle choices that can help athletes reach their potential. Improving education in these areas, preparing athletes for these changes, and showing examples of what to expect as they transition into professional sports can benefit the athletes, the universities and colleges in which they are educated, the franchises in which they are drafted, and the communities where they reside. This information can be delivered through a handbook while having in-person training that can build upon each session to dive deeper into each given topic while building relationships with the athletes.
ContributorsMurphy, Flynn (Author) / Spies, Lindsey (Co-author) / McIntosh, Daniel (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor)
Created2023-05
ContributorsMurphy, Flynn (Author) / Spies, Lindsey (Co-author) / McIntosh, Daniel (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor)
Created2023-05
ContributorsMurphy, Flynn (Author) / Spies, Lindsey (Co-author) / McIntosh, Daniel (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor)
Created2023-05
ContributorsMurphy, Flynn (Author) / Spies, Lindsey (Co-author) / McIntosh, Daniel (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor)
Created2023-05