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This research investigates the whether dietary and nutritional treatments will improve some of the symptoms of autism. This treatment includes a combination of 6 nutritional and dietary treatments, which are vitamins/minerals, essential fatty acids, Epsom salts, carnitine, digestive enzymes, and healthy gluten-free, casein-free diet. 55 participants were involved in this

This research investigates the whether dietary and nutritional treatments will improve some of the symptoms of autism. This treatment includes a combination of 6 nutritional and dietary treatments, which are vitamins/minerals, essential fatty acids, Epsom salts, carnitine, digestive enzymes, and healthy gluten-free, casein-free diet. 55 participants were involved in this study; 28 participants are in the Treatment Group and 27 participants in the Delayed Group. Data from the PDD-BI form, the ADOS form, the CARS form and the professional SAS form will be used in this thesis project for analyses. Factors analyzed are age, gender and severity [initial professional SAS data] and then correlating these factors with data from PDD-BI (autism composite score and each subscale), ADOS and CARS. The data analyses show that changing the dietary and nutritional needs of children/adults with autism improves the symptoms of autism (as rated by the PDD-BI) by approximately 22% in the treatment group vs. 3% in the non-treatment group, p<0.001. Overall, these results also suggest that the treatment is equally beneficial for males and females of varying age (young children to adult) and of all severity levels.
ContributorsLee, Chiao May (Author) / Adams, James B. (Thesis director) / Pollard, Elena (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2015-05
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This paper begins by exploring the prior research that has shown how eating a plant-based diet can affect the human body. Some of these effects include: improved mood, energy levels, gut health, alkalized urine pH, as well as, lowering the risk of hormonal imbalance, kidney stones, diabetes, cancer, and coronary

This paper begins by exploring the prior research that has shown how eating a plant-based diet can affect the human body. Some of these effects include: improved mood, energy levels, gut health, alkalized urine pH, as well as, lowering the risk of hormonal imbalance, kidney stones, diabetes, cancer, and coronary artery disease. The worries that generally accompany eating a fully vegan diet, which include, malnutrition and protein deficiency, are also addressed in the background research. In attempt to build upon previous research, a weeklong experiment was conducted testing 3 different factors, which include: gut health, improved mood, and urine pH. Mood states were measured quantifiably using a POMS (profile of mood states) test. Gut health was measured using several factors, including consistency and frequency of bowel movements, as well as, GI discomfort. Two 24-hour urine samples were collected from each of the subjects to compare the pH of their urine before and after the study. The sample size of this study included 15 healthy, non-smoking, subjects, between 18-30 years of age. The subjects were split up into 3 stratified random samples, including, an omnivore control group, vegan control group, and experimental vegan group. The experimental vegans had eaten meat/eggs/dairy regularly for their whole lives before the start of the study, and had consented to eating a vegan diet for the entirety of one week. While the data from the control groups remained mostly constant as predicted, the results from the experimental group were shown to have a significantly better mood (P<0.05) after one week, as well as, a significantly higher urine pH (P < 0.025) than they did before the study. However, the experimental group did not show a significant change in stool frequency, consistency, or GI discomfort within one week. The vegan control group, which included subjects who had eaten a plant-based diet for 1-3 years, had much better gut health scores. This leads us to believe that the vegan gut microbiome takes much longer to transform into than just one week unlike urine pH and mood, which can take as little as one week. These findings warrant further investigation.
ContributorsMacias, Lindsey Kaori (Author) / Johnston, Carol (Thesis director) / Katsanos, Christos (Committee member) / Harrington Bioengineering Program (Contributor) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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One of the great difficulties in leading America to become a healthier nation involves overcoming the socioeconomic disparity that exists between income and health literacy. Impoverished communities consistently lack the proper health education to make quality food purchases and healthy lifestyle choices, leading to higher rates of obesity. Through FitPHX

One of the great difficulties in leading America to become a healthier nation involves overcoming the socioeconomic disparity that exists between income and health literacy. Impoverished communities consistently lack the proper health education to make quality food purchases and healthy lifestyle choices, leading to higher rates of obesity. Through FitPHX Energy Zones, an after-school program designed to encourage Phoenix youths to lead healthier lifestyles through an innovative use of library spaces, I provided health education and opportunities for physical activity for 8 to 14-year-olds in underserved Phoenix communities. However, although this intervention made significant progress with the kids' health literacy development over the course of the program, it is difficult for community-based intervention programs to continue in the long run due to budget or other extraneous circumstances. Once the program ends, there needed to be a way to continue to reach the kids beyond the scope of the program such that they can continue to experience the lessons taught during the program. Following the conclusion of FitPHX, I created an interactive book for the kids I worked with to help them retain the health and nutrition knowledge taught during the program.
ContributorsBejarano, Michael Carlos (Author) / McCoy, Maureen (Thesis director) / Williams, Deborah (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Nutritional support offered before and during chemotherapy treatment is proven to improve the outcomes of treatment (Bernhardson, 2016). This project seeks to examine current forms of nutritional support offered to patients, as well as the models of care and support teams in cancer treatment centers. The basis for this project

Nutritional support offered before and during chemotherapy treatment is proven to improve the outcomes of treatment (Bernhardson, 2016). This project seeks to examine current forms of nutritional support offered to patients, as well as the models of care and support teams in cancer treatment centers. The basis for this project incorporated personal experiences at M.D. Anderson Cancer Center in Gilbert, Arizona as well as research into the work of clinical oncology dietitians. An intense interest in food videos and blogs also informed this project, and was incorporated in the hope of providing chemotherapy patients a platform to discover recipes specific to their unique situation. The combination of this research was utilized to create several videos which demonstrated specific recipes beneficial for patients as well as creating a platform for this particular population. While nutritional support can take multiple forms, the focus of nutritional support surrounds symptom management. The common side effects of chemotherapy such as nausea, mucositis (mouth sores), and extreme weight loss were taken into account. Recipes were formulated to directly address these conditions and each recipe was broken down into the benefits of both macronutrients and micronutrients. In addition to formulating specific recipes and videos, barriers to proper nutritional support were examined and explained. These barriers include understaffing of clinical dietitians at cancer treatment centers, a patient's lack of transportation to and from treatments, as well as an overwhelming viewpoint that nutritional support is only required for extreme cases of malnutrition. Combatting these barriers and offering more forms of nutritional support will help to increase a patient's positive response to treatment, manage their symptoms, and improve their overall quality of life.
ContributorsMonteilh, Christina Eleanor (Author) / Levinson, Simin (Thesis director) / Martinelli, Sarah (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
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Injury Prevention of Young Adult Competitive Athletes Abstract: This literature review covers many aspects of health and injury prevention that affects the young adult population. This review will begin to formulate a general guideline for sustaining performance while minimizing the incidence for injury. This population is specifically narrowed down to

Injury Prevention of Young Adult Competitive Athletes Abstract: This literature review covers many aspects of health and injury prevention that affects the young adult population. This review will begin to formulate a general guideline for sustaining performance while minimizing the incidence for injury. This population is specifically narrowed down to competitive athletes between the ages of 16-22. Some of the topics covered in this paper are the effects of macro-nutrients and micro-nutrients such as iron, calcium, vitamin D and vitamin C, on the body. Along with relating nutrition to lowering the risk of injury, there are also other topics covered such as sleep, stress relief in the form of binaural sounds, training and over-training. Nutrition topics include carbohydrates, proteins and fats, which are then split into their respective roles inside the body. These macro-nutrients are also associated with recovery and the timing and quantity consumed can be at optimal levels for competitive athletes based on gender, age and size. The vitamins and minerals discussed are also important factors in injury prevention related to bone, ligament and muscle strength. These micro-nutrients are also related to hormone regulation and immune system response which are necessary in mitigating the risk of injury in the population being analyzed. Finally, there is a training section of this literary review which covers monitoring external and internal loads experienced by the athletes, movement patterns as well as flexibility, and how to respond to over-training syndrome and overreaching in young adult athletes. Creating a balance between all aspects covered will result in a high likelihood of reducing the risk for injury in the young adult population.
ContributorsMark, Colby Jordan (Author) / Levinson, Simin (Thesis director) / Feser, Erin (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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With dwindling water resources due to drought and other pressures, water utilities are seeking to tap into alternative water sources as a means to improve water sustainability. Reclaimed water consists of treated wastewater and is widely used for non-potable purposes, such as irrigation, both agricultural and recreational. However, the reclaimed

With dwindling water resources due to drought and other pressures, water utilities are seeking to tap into alternative water sources as a means to improve water sustainability. Reclaimed water consists of treated wastewater and is widely used for non-potable purposes, such as irrigation, both agricultural and recreational. However, the reclaimed water distribution system can be subject to substantial regrowth of microorganisms, including opportunistic pathogens, even following rigorous disinfection. Factors that can influence regrowth include temperature, organic carbon levels, disinfectant type, and the time transported (i.e., water age) in the system. One opportunistic pathogen (OP) that is critical to understanding microbial activity in both reclaimed and drinking water distribution systems is Acanthamoeba. In order to better understand the potential for this amoeba to proliferate in reclaimed water systems and influence other OPs, a simulated reclaimed water distribution system was studied. The objective of this study was to compare the prevalence of Acanthamoeba and one of its endosymbionts, Legionella, across varying assimilable organic carbon (AOC) levels, temperatures, disinfectants, and water ages in a simulated reclaimed water distribution system. The results of the study showed that cooler temperatures, larger water age, and chlorine conditions yielded the lowest detection of Acanthamoeba gene copies per mL or cm2 for bulk water and biofilm samples, respectively.
ContributorsDonaldson, Kandace (Author) / Ankeny, Casey (Thesis director) / Edwards, Marc (Committee member) / Pruden, Amy (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
For this creative project, the student's overarching objective was to establish a signature dish and to learn how to cook. She acquired a cookbook fit for novice cooks, "Eat What You Love" by Marlene Koch, which focused on healthy eating through the reduction of sugar and fat. The student completed

For this creative project, the student's overarching objective was to establish a signature dish and to learn how to cook. She acquired a cookbook fit for novice cooks, "Eat What You Love" by Marlene Koch, which focused on healthy eating through the reduction of sugar and fat. The student completed thirty recipes including two appetizers, five breakfast entrees, five lunch entrees, twelve dinner entrees, and six desserts. Her culinary ventures were then detailed through a blog site the student had created. Blog posts included a brief description primarily of the portion size, a nutritional analysis of the recipe, enjoyable aspects of the dish, whether something went wrong, what was learned from creating the dish, as well as a photograph of the prepared dish. A large element of this project focused upon food photography and obtaining images that made the created dish look appealing. It was found that the best images were taken in natural lighting with good compositions and pops of color. In order to gain readership, the student developed an Instagram account where she would post images of the food and provide links to her blog entries and recipes. Through this means, she was able to obtain over 100 followers to her blog. In addition to learning how to cook, the student sought out to understand components of a healthy diet and how each nutrient contributes to an individual health. This objective is detailed throughout the course of the paper as well as several other objectives. The student also studied how social media has impacted the way in which we share food and our knowledge of food. Additionally in this paper, the student evaluated the evolution of the USDA Dietary Guidelines and their effectiveness over time. From this project, the student walked away with new knowledge about nutritional eating and lifestyle habits that she will retain for years to come. She hopes that this project will encourage other students to take on their own culinary adventure.
ContributorsMarley, Allison Marie (Author) / Levinson, Simin (Thesis director) / Martinelli, Sarah (Committee member) / Harrington Bioengineering Program (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Water is an essential nutrient that is often overlooked. As a result of this hydration status is often forgotten as well. Becoming hypohydrated puts athletes at risk of decreased performance and potentially life-threatening heat illness. Being able to self-assess hydration status is may be instrumental in helping athletes safely optimize

Water is an essential nutrient that is often overlooked. As a result of this hydration status is often forgotten as well. Becoming hypohydrated puts athletes at risk of decreased performance and potentially life-threatening heat illness. Being able to self-assess hydration status is may be instrumental in helping athletes safely optimize performance. Therefore, this study investigated, 1) the ability of an athletic population vs. trained investigators to self-diagnose underhydration, 2) the diagnostic ability of urine color (Ucol) charts as a method for diagnosing underhydration, and 3) the accuracy of participant and investigator assessments. Members of an athletic population each provided a urine sample and scored samples using both the traditional 8-color and newly developed 7-color Ucol chart. Investigators then scored the samples using the same methods. To determine the diagnostic value of the Ucol charts, Ucol scores were compared to concentration measures of Urine Specific Gravity (USG) and Urine Osmolality (Uosm). Differences in participant and investigator scores were compared using Mann-Whitney U and Spearman’s Correlation. Bland-Altman plots were drawn to assess individual differences in reporting against the mean of the two methods. Receiver Operating Characteristic (ROC) analysis was used to both determine the ability of both charts to diagnose underhydration and to determine how well participants and investigators can determine their level of hydration. Athletes reported Ucol significantly lighter compared to investigators. Investigators showed no difference in reporting between the two charts but, athletes reported less than a color shade difference. The charts performed fair (8-color) to good (7-color) at diagnosing hypohydration. Athletes reported with less accuracy compared to investigators, and Ucol classification was found to be more accurate when compared to USG. Ucol charts are a practical tool to determine hydration status. Ucol scoring is similar regardless of the type of chart used. Trained investigators reported with slightly higher accuracy on both charts compared to untrained athletes. Athletes score Ucol fair to good in comparison to investigators. Ucol scoring is similar regardless of the type of chart used. The diagnostic ability of both Ucol charts is good in relation to USG. With education, athletes may be able to improve scores.
ContributorsPesek, Kathryn Margaret (Author) / Wardenaar, Floris (Thesis advisor) / Johnston, Carol (Committee member) / Yudell, Amber (Committee member) / Arizona State University (Publisher)
Created2022
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Heat acclimatization can be induced by targeting a core temperature 38.5°C for at least 60 minutes per day lasting 5 to 21 days, complementary to normal exercise activity. However, consistently meeting this threshold on consecutive days may be difficult for athletes. The objective of this study was to evaluate the

Heat acclimatization can be induced by targeting a core temperature 38.5°C for at least 60 minutes per day lasting 5 to 21 days, complementary to normal exercise activity. However, consistently meeting this threshold on consecutive days may be difficult for athletes. The objective of this study was to evaluate the efficacy of four single-bout heating protocols to reach a core temperature 38.5°C. The study was set up as a non-randomized field study, factoring in the September-October outdoor desert conditions, Tempe, AZ, USA. Environmental conditions were measured using a Kestrel heat stress tracker. Protocols were constituted out of 3 elements: PAS – passive heat exposure in a tent (54±1°C), EH - exercise in hot condition with high intensity interval training (HIIT) outdoors in the heat in a tent with a ventilator (43±1°C), EM – exercise in moderate conditions with HIIT indoors (22±0.4°C). All participants performed protocols in the following order: 1) PAS 60-min; 2) EH-PAS (EH 30-min + PAS 30-min); 3) EH 60-min, and 4) EM 60-min. A cycle ergometer was used for HIIT (2-min warm-up followed by 7x2-min sprints with 2-min relative rest between sprints during the first 30 min and stationary cycling for the second 30 min), with a self-selected workload at 80-100 rpm and similar heart rate (HR) response during exercise testing for EH: 146±10, EM: 142±13, and EH-PAS: 142±13 (P>0.05). A total of 10 active male students (25±3 years old) reported no difference between protocols for baseline Tc (P=0.37) and HR (P=0.28). During the first 30-min, Tc was significantly different between protocols (average ranging from 37.3-37.6°C, P=0.01), but from a practical perspective, differences were limited. During the second 30-min session, the Tc for EH (38.5±0.4°C) and EH-PAS (38.6±0.4°C) were significantly higher from EM (38.1±0.4°C) and PAS alone (37.8±0.4°C), P<0.001. The average HR (bpm) was significantly lower in PAS (110±17) and EH (136±13) during the second half of the protocols compared to the EH (151±10) and EM (149±16), P<0.001. In conclusion, exercise alone vs. a combination of exercise and passive heating in hot conditions resulted both in a body temperature 38.5°C, but the combination was more efficient since participants exercised for only 30-minutes.
ContributorsNavarro, Sonia (Author) / Wardenaar, Floris (Thesis advisor) / Kavouras, Stavros (Committee member) / Vanos, Jennifer (Committee member) / Arizona State University (Publisher)
Created2022
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The purpose of this study was to evaluate the impact of improved hydration on endurance performance and mood in physically active adults. Participants (n = 72; age, 21.0 ± 3.0; 22.2% female) completed two two-mile run trials separated by exactly a week. Before each trial, participants provided a urine sample

The purpose of this study was to evaluate the impact of improved hydration on endurance performance and mood in physically active adults. Participants (n = 72; age, 21.0 ± 3.0; 22.2% female) completed two two-mile run trials separated by exactly a week. Before each trial, participants provided a urine sample from the day before the run and a sample from the morning of the run. These samples were analyzed for urine osmolality (UOsm), urine specific gravity (USG), and urine color (Ucol). UOsm and USG levels determined if the participants were placed in either the euhydrated or underhydrated group after the first trial. Those assigned to the euhydrated group were instructed to maintain their current fluid intake levels and those in the underhydrated group were instructed to increase fluid intake levels before the second trial. However, results were grouped by if they improved or maintained their hydration or not. The subjects also completed a Profile of Mood States (POMS) questionnaire before and after each trial to determine mood. Based on conditioning requirements for group assignment, 38% of subjects were classified as underhydrated. There were significant differences between the two trials for both subjects that improved and worsened their hydration in UOsm, USG, Ucol, and thirst (P < 0.05). The group with improved hydration ran -15 ± 67 sec faster in the second trial, while the group that worsened hydration ran 4 ± 26 sec slower in the second trial. When these differences were compared between the two groups with a t-test, there was a trend for statistical differences with a one-way t-test analysis (P = 0.06). When results were split by sex no statistically significant differences were observed (male: -10.8 ± 63.6 sec; female: -29.4 ± 94.8 sec; P > 0.05). Improved hydration did not result in statistically significant difference in TMD or any of the individual mood sub-scales for either group for both males and females (P > 0.05). In conclusion, increased fluid intake to optimize hydration status may affect endurance exercise in young, healthy adults in a two-mile run, but no effect was seen on mood.
ContributorsDoyle, Amanda Ann (Author) / Kavouras, Stavros (Thesis advisor) / Alexon, Christy (Committee member) / Wardenaar, Floris (Committee member) / Arizona State University (Publisher)
Created2022