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Description
Cannabis use is increasing both medically and recreationally. Over the last decade studies have investigated sex differences associated with Parkinson’s disease (PD) diagnosis and degenerative symptoms. Previous research has shown that cannabis use has had either a beneficial or deleterious effect on PD symptoms. This research will examine whether sex

Cannabis use is increasing both medically and recreationally. Over the last decade studies have investigated sex differences associated with Parkinson’s disease (PD) diagnosis and degenerative symptoms. Previous research has shown that cannabis use has had either a beneficial or deleterious effect on PD symptoms. This research will examine whether sex differences exist among the positive or negative effects of cannabis use in PD. In this paper, an analysis of sex-based differences between male and female cohorts categorized across 2,700 participants is completed under the Fox Insight data set. Each cohort will be compared to 14 nonmotor symptoms and 8 motor symptoms commonly associated with PD. In each cohort mean age, cannabis intake, cannabis dose, cannabis type, and PD diagnosis are analyzed within groups. Each symptom (motor and nonmotor) was analyzed between cohort responses to indicate if there was beneficial or worsening effect within cannabis. Results indicated that the designated female cohort reported both beneficial and worsening effects of cannabis use regarding both motor and nonmotor symptoms. The positive symptoms primarily consisted of individual motor functioning (e.g. dyskinesia, stiffness, back pain, etc.) while the worsening symptoms primarily consisted of nonmotor functioning (e.g. anxiety and apathy). Meanwhile, the male cohort only reported beneficial effects towards nonmotor symptoms (e.g. dystonia, muscle cramps, heart rate). These findings suggest the need for further examination of nigrostriatal pathways and hypothalamic integrity in PD, as it may provide more information into the effects of cannabis use based on sex differences.
ContributorsHooten, Madeline Loraine (Author) / Ofori, Edward (Thesis advisor) / Daniulaityte, Raminta (Committee member) / Peterson, Daniel (Committee member) / Arizona State University (Publisher)
Created2022
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Description

Cannabinoid (CBD) is a product from the cannabis plant that has shown to provide many benefits and little risk of side effects. A survey was conducted with a focus on three populations: athletes, performers, and the general population. It was found that 23 out of 58 participants (40%) use CBD

Cannabinoid (CBD) is a product from the cannabis plant that has shown to provide many benefits and little risk of side effects. A survey was conducted with a focus on three populations: athletes, performers, and the general population. It was found that 23 out of 58 participants (40%) use CBD for a variety of reasons. 35% of CBD users use it for anxiety, 39% use it for soreness, and 26% use it for other reasons. Out of the 35 participants who do not use CBD 15 people said they would be willing to try CBD products. It was found that while people who use CBD found it to be effective many people throughout all three populations do not have much knowledge about CBD and its benefits. As more research is conducted and released, more people will be inclined to use it.

ContributorsBennifield, Isis (Author) / Vezina, Jesse (Thesis director) / Bingham, Garett (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor) / School of Music, Dance and Theatre (Contributor)
Created2022-05