This thesis project is the result of close collaboration with the Arizona State University Biodesign Clinical Testing Laboratory (ABCTL) to document the characteristics of saliva as a test sample, preanalytical considerations, and how the ABCTL utilized saliva testing to develop swift COVID-19 diagnostic tests for the Arizona community. As of April 2021, there have been over 130 million recorded cases of COVID-19 globally, with the United States taking the lead with approximately 31.5 million cases. Developing highly accurate and timely diagnostics has been an important need of our country that the ABCTL has had tremendous success in delivering. Near the start of the pandemic, the ABCTL utilized saliva as a testing sample rather than nasopharyngeal (NP) swabs that were limited in supply, required highly trained medical personnel, and were generally uncomfortable for participants. Results from literature across the globe showed how saliva performed just as well as the NP swabs (the golden standard) while being an easier test to collect and analyze. Going forward, the ABCTL will continue to develop high quality diagnostic tools and adapt to the ever-evolving needs our communities face regarding the COVID-19 pandemic.
3D printing prosthetics for amputees is an innovative opportunity to provide a lower cost and customized alternative to current technologies. Companies, such as E-NABLE and YouBionic are developing myoelectric prosthetics, electrically powered terminal devices activated by electromyography (EMG), for transradial amputees. Prosthetics that are 3D printed are less expensive for juvenile use, more sustainable, and more accessible for those without insurance. Although they are typically not outfitted with the same complex grip patterns or durability of a traditional myoelectric prosthetic, they offer a sufficient durability (withstanding up to 150 N on average) and allow for new opportunities in prosthetic development. Devils Prosthetics, a student research and development group associated with Engineering Projects in Community Service (EPICS), has investigated the benefits and pitfalls of utilizing polyethylene terephthalate glycol (PETG) for 3D printing prosthetics as well as combining a MyoWare EMG sensor with machine learning for optimal control of the prosthetic.
3D printing prosthetics for amputees is an innovative opportunity to provide a lower cost and customized alternative to current technologies. Companies, such as E-NABLE and YouBionic are developing myoelectric prosthetics, electrically powered terminal devices activated by electromyography (EMG), for transradial amputees. Prosthetics that are 3D printed are less expensive for juvenile use, more sustainable, and more accessible for those without insurance. Although they are typically not outfitted with the same complex grip patterns or durability of a traditional myoelectric prosthetic, they offer a sufficient durability (withstanding up to 150 N on average) and allow for new opportunities in prosthetic development. Devils Prosthetics, a student research and development group associated with Engineering Projects in Community Service (EPICS), has investigated the benefits and pitfalls of utilizing polyethylene terephthalate glycol (PETG) for 3D printing prosthetics as well as combining a MyoWare EMG sensor with machine learning for optimal control of the prosthetic.