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Description
Phase contrast magnetic resonance angiography (PCMRA) is a non-invasive imaging modality that is capable of producing quantitative vascular flow velocity information. The encoding of velocity information can significantly increase the imaging acquisition and reconstruction durations associated with this technique. The purpose of this work is to provide mechanisms for reducing

Phase contrast magnetic resonance angiography (PCMRA) is a non-invasive imaging modality that is capable of producing quantitative vascular flow velocity information. The encoding of velocity information can significantly increase the imaging acquisition and reconstruction durations associated with this technique. The purpose of this work is to provide mechanisms for reducing the scan time of a 3D phase contrast exam, so that hemodynamic velocity data may be acquired robustly and with a high sensitivity. The methods developed in this work focus on the reduction of scan duration and reconstruction computation of a neurovascular PCMRA exam. The reductions in scan duration are made through a combination of advances in imaging and velocity encoding methods. The imaging improvements are explored using rapid 3D imaging techniques such as spiral projection imaging (SPI), Fermat looped orthogonally encoded trajectories (FLORET), stack of spirals and stack of cones trajectories. Scan durations are also shortened through the use and development of a novel parallel imaging technique called Pretty Easy Parallel Imaging (PEPI). Improvements in the computational efficiency of PEPI and in general MRI reconstruction are made in the area of sample density estimation and correction of 3D trajectories. A new method of velocity encoding is demonstrated to provide more efficient signal to noise ratio (SNR) gains than current state of the art methods. The proposed velocity encoding achieves improved SNR through the use of high gradient moments and by resolving phase aliasing through the use measurement geometry and non-linear constraints.
ContributorsZwart, Nicholas R (Author) / Frakes, David H (Thesis advisor) / Pipe, James G (Thesis advisor) / Bennett, Kevin M (Committee member) / Debbins, Josef P (Committee member) / Towe, Bruce (Committee member) / Arizona State University (Publisher)
Created2011
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Description
Magnetic Resonance Imaging using spiral trajectories has many advantages in speed, efficiency in data-acquistion and robustness to motion and flow related artifacts. The increase in sampling speed, however, requires high performance of the gradient system. Hardware inaccuracies from system delays and eddy currents can cause spatial and temporal distortions in

Magnetic Resonance Imaging using spiral trajectories has many advantages in speed, efficiency in data-acquistion and robustness to motion and flow related artifacts. The increase in sampling speed, however, requires high performance of the gradient system. Hardware inaccuracies from system delays and eddy currents can cause spatial and temporal distortions in the encoding gradient waveforms. This causes sampling discrepancies between the actual and the ideal k-space trajectory. Reconstruction assuming an ideal trajectory can result in shading and blurring artifacts in spiral images. Current methods to estimate such hardware errors require many modifications to the pulse sequence, phantom measurements or specialized hardware. This work presents a new method to estimate time-varying system delays for spiral-based trajectories. It requires a minor modification of a conventional stack-of-spirals sequence and analyzes data collected on three orthogonal cylinders. The method is fast, robust to off-resonance effects, requires no phantom measurements or specialized hardware and estimate variable system delays for the three gradient channels over the data-sampling period. The initial results are presented for acquired phantom and in-vivo data, which show a substantial reduction in the artifacts and improvement in the image quality.
ContributorsBhavsar, Payal (Author) / Pipe, James G (Thesis advisor) / Frakes, David (Committee member) / Kodibagkar, Vikram (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The goal of the works presented in this volume is to develop a magnetic resonance imaging (MRI) probe for non-invasive detection of extracellular matrix (ECM) underlying fenestrated endothelia. The ECM is the scaffold that supports tissue structure in all organs. In fenestrated structures the such as the kidney glomerulus and

The goal of the works presented in this volume is to develop a magnetic resonance imaging (MRI) probe for non-invasive detection of extracellular matrix (ECM) underlying fenestrated endothelia. The ECM is the scaffold that supports tissue structure in all organs. In fenestrated structures the such as the kidney glomerulus and the hepatic sinusoid the ECM serves a unique role in blood filtration and is directly exposed to blood plasma. An assessment of the ECM in fenestrated organs such as the kidney and liver reports on the organ's ability to filter blood - a process critical to maintaining homeostasis. Unfortunately, clinical assessment of the ECM in most organs requires biopsy, which is focal and invasive. This work will focus on visualizing the ECM underlying fenestrated endothelia with natural nanoparticles and MRI. The superparamagnetic ferritin protein has been proposed as a useful naturally-derived, MRI-detectable nanoparticle due to its biocompatibility, ease of functionalization, and modifiable metallic core. We will show that cationized ferritin (CF) specifically binds to the anionic proteoglycans of the ECM underlying fenestrated endothelia and that its accumulation is MRI-detectable. We will then demonstrate the use of CF and MRI in identifying and measuring all glomeruli in the kidney. We will also explore the toxicity of intravenously injected CF and consider other avenues for its application, including detection of microstructural changes in the liver due to chronic liver disease. This work will show that CF is useful in detected fenestrated microstructures in small animals and humans alike, indicating that CF may find broad application in detecting and monitoring disease in both preclinical and clinical settings.
ContributorsBeeman, Scott (Author) / Bennett, Kevin M (Thesis advisor) / Kodibagkar, Vikram D (Committee member) / Fayad, Zahi A (Committee member) / Pizziconi, Vincent B (Committee member) / Pipe, James G (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Luxury is a sector of all global industry that has been proven sustainable, having flourished during global economic successes and withstood hardships across numerous decades. Consumers are drawn to luxury, both the physical and perceived value that luxury products offer. Luxury champagne tastes better, luxury vehicles are higher performing and

Luxury is a sector of all global industry that has been proven sustainable, having flourished during global economic successes and withstood hardships across numerous decades. Consumers are drawn to luxury, both the physical and perceived value that luxury products offer. Luxury champagne tastes better, luxury vehicles are higher performing and luxury fashion reflects the highest quality designs. The belief in superior product is what keeps luxury relevant. However, it is the brand identity created on behalf of the firm behind a luxury brand that remains the vital component to develop and maintain its top-tier status. Luxury fashion firms are synonymous with their brand, the persona and user experience created driving all facets of creative and business execution. While product name and perceived value are contributors to global success, the evolution and maintenance of such status relies upon the consistency of brand identity. To begin, I will identify a criterion that differentiates luxury fashion (mega-brands) from mass-market and commercial fashion, as well as outline the components that comprise a luxury brand identity. After a clear understanding of the meaning of luxury is established, I will layout the process of how a brand identity is consistently communicated through the business cycle, from the initial creation and design process to the end point of the final sale stage. To further enrich the learning established, I will apply the developed concepts in a dissection of the top five luxury fashion firms, Chanel, Dior, Louis Vuitton, Prada and Gucci. Analyzing each mega-brand, I will evaluate how the company's brand identity has evolved over the course of the firm's heritage and analyze the current brand creative direction (brand identity, ethics and aesthetics). Understanding the brand's persona and image, I will highlight the physical representation through brand codes and symbols to support the firm's positioning as a thriving luxury empire. Lastly, I will interpret the company's latest advertising campaign, deconstructing the application of brand identity as well as the contribution the campaign provides to supporting firm success. Ultimately, after gaining sufficient understanding of what a successful luxury firm is comprised of, I will identify the shortcomings identified within the last firm evaluated, Gucci. I will examine the branding failures of the current state of Gucci, analyzing what contributed to its fall from top luxury brand status. Additionally, I will provide details regarding what measures are currently being taken to regain its superior status as well as provide my own recommendation to the firm. In summation, through the process of understanding successful luxury branding practices, I hope to have enriched not only my understanding of brand identity but have gained the ability to develop my own point of view, to suggest a branding path and measures to be taken to steer Gucci back on a track.
ContributorsGil, Alexandria Southwick (Author) / Peck, Sidnee (Thesis director) / Ostrom, Amy (Committee member) / Barrett, The Honors College (Contributor) / Department of Management (Contributor) / Department of Marketing (Contributor)
Created2015-05
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Description
As a self-discrepancy arises between who an individual currently is and who they aspire to become, feelings of tension arise. Reactions to this stress are based on various personal beliefs. Our feelings of our potential to reach our desired state can be affected by our orientation of locus of control,

As a self-discrepancy arises between who an individual currently is and who they aspire to become, feelings of tension arise. Reactions to this stress are based on various personal beliefs. Our feelings of our potential to reach our desired state can be affected by our orientation of locus of control, or where we believe control is derived from within our life. In the present research, we examine how a person's locus of control--whether they are internal by attributing outcomes to their own actions or external believers that fate and chance drive their life outcomes--affects their reaction to a self-discrepancy in a domain that is important to them, and how this affects valuation of the products used in that domain. We found that while internals and externals behave similarly under feelings of high competence (baseline condition) when a self-discrepancy is not evident, reactions differed under the opposing condition of feeling less competent during their goal pursuit. Externals did not significantly change their belief in the product regardless of the condition (high vs. low competence) while internals took the defeat heavily by significantly decreasing their belief that the goal-related product would help them achieve their goals and decreased their willingness to pay for it.
ContributorsSweet, Megan Ruth (Author) / Samper, Adriana (Thesis director) / Ostrom, Amy (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor) / Department of Management (Contributor)
Created2015-05
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Description
Tech2Learn, a privately owned tutoring company, serves students in kindergarten through eighth grade at its Phoenix location. The company's founding mission "is for every child to build individual competence and confidence in essential skills." It accomplishes this mission by providing a safe, fun, and engaging environment where children feel comfortable

Tech2Learn, a privately owned tutoring company, serves students in kindergarten through eighth grade at its Phoenix location. The company's founding mission "is for every child to build individual competence and confidence in essential skills." It accomplishes this mission by providing a safe, fun, and engaging environment where children feel comfortable learning. In addition to tutoring in traditional subjects such as math and reading, Tech2Learn also offers a dyslexia reading lab, and a High School Placement Test prep course. The goal of this plan is to find a low cost and easy to manage way for Tech2Learn to market its services and encourage referrals. To achieve this goal, I conducted both an external and internal analysis. In order for Tech2Learn to remain competitive in the industry, it must be aware of trends such as the rapidly evolution of teaching technology, new government mandates on curriculum, and parents' desire to be involved in their children's education. While these trends create opportunities for growth, there are also threats that arise. One threat to Tech2Learn is a large number of competitors in the market. The company relies on its strengths of human capital and unique teaching approach to minimize these threats. The tactics and strategies recommended in this plan are intended to reduce the company's weaknesses. Specifically, tactical recommendations target Tech2Learn's digital presence through the creation of a Facebook page, consolidation of company owned web domains, and updating business information on both owned and earned online sites. Additionally, strategic suggestions aim to prepare Tech2Learn for future growth through the implementation of a formal training procedure, consideration of an additional office location, and differentiation through the early adoption of new technologies, such as virtual reality.
ContributorsCunningham, Sinead Bridget (Author) / Ostrom, Amy (Thesis director) / Giles, Bret (Committee member) / Cummings, Deborah (Committee member) / Department of Marketing (Contributor) / Department of Management (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
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Description
This project investigates how experiences colleges create for admitted students impact students' excitement for, satisfaction with, and likelihood to attend the college, analyzed by different subgroups, and how non-yielded students compare their college selection to W. P. Carey on various metrics. This study found that top admit students were less

This project investigates how experiences colleges create for admitted students impact students' excitement for, satisfaction with, and likelihood to attend the college, analyzed by different subgroups, and how non-yielded students compare their college selection to W. P. Carey on various metrics. This study found that top admit students were less likely to attend, less satisfied, and less excited with the services offered than their counterparts and recommendations were made to improve the gap.
ContributorsGullo, Kelley (Co-author) / Dwosh, Bennett (Co-author) / Ostrom, Amy (Thesis director) / Olsen, Douglas (Committee member) / Desch, Timothy (Committee member) / Barrett, The Honors College (Contributor) / Department of Economics (Contributor) / Department of Marketing (Contributor) / School of Human Evolution and Social Change (Contributor) / Department of Management (Contributor) / W. P. Carey School of Business (Contributor)
Created2015-05
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Description
The objective of this paper is to give information that can assist Independent (indie) authors at every stage of the book process: development, promotion and distribution of their books. The book market is changing, and it's changing today. As the market evolves it is essential for authors to evolve as

The objective of this paper is to give information that can assist Independent (indie) authors at every stage of the book process: development, promotion and distribution of their books. The book market is changing, and it's changing today. As the market evolves it is essential for authors to evolve as well. Due to the market's evolution, authors must question every stage of the book process, from beginning to end. It is due to these significant changes that my paper will be formatted more as a guide for newer indie authors or authors who are having trouble keeping up with the new market. The guide will assist indie authors at every stage of the book process and will also make clear where the new market stands. In order to create a more credible guide, I collected large amounts of primary data and entered the market myself in order to truly understand the new market from an indie author's position. I found this approach essential due to the near absence of credible secondary data and because of the plethora of nuances at every stage of the book process. For primary data, I created and distributed an in-depth survey with the purpose of revealing book blogger preferences, online habits, and preferred methods of contact. The reason for my focus on book bloggers is because of the greatly increased importance of book reviews. I also believe that book blogger preferences are a good indicator of what the typical reader enjoys, giving me further insight into market preferences as a whole. I became an indie author in order to better understand the market so that I could ask the right questions and be better able to give practical suggestions. I wanted to create a guide that real indie authors could use, so it seemed natural that I should become a real indie author. This guide is structured in the way indie authors would create their book.
ContributorsCollopy, Robert Edward (Author) / Ostrom, Amy (Thesis director) / Eaton, John (Committee member) / Barrett, The Honors College (Contributor) / Department of Finance (Contributor) / Department of Marketing (Contributor)
Created2014-05
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Description
This thesis aims to enhance K-6 Education in the United States by developing recommendations for how technology is utilized in the classroom as a means to teach collaborative skills. By applying the technological capabilities we have today to the Common Core State Standards that are gradually being adopted and implemented,

This thesis aims to enhance K-6 Education in the United States by developing recommendations for how technology is utilized in the classroom as a means to teach collaborative skills. By applying the technological capabilities we have today to the Common Core State Standards that are gradually being adopted and implemented, officials can improve the quality of education across the country and create classroom environments conducive to knowledge acquisition and skill development.
The research begins with the history of standards, starting with traditional outcome-based standards. It then delves into the Partnership for 21st Century Skills (P21), which highlights the type of skills 21st century students are expected to develop and master by the time they enter college and careers. Next, it explores the hot topic of Education to this date: Common Core State Standards. In the midst of educational reform, these standards seek to add consistency across the nation in regards to what students should know at each grade level and also encourage teaching of the 21st century skills. This section briefly details the content of Common Core English Language Arts and Mathematics standards.
After summarizing P21 and Common Core, this report shifts into its focused 21st century skill: collaboration. As one of the 4 C’s that P21 and Common Core emphasize in their standards, it is imperative to research critical elements of collaboration as they relate to groups and teams of all ages. Even more specifically, collaboration is a practice that is becoming more and more standard in business across all industries, so it is a skill that is highly in demand for students to acquire. In regards to collaboration, Executive Vice President of Verizon, Bob Mudge, states, “companies are able to innovate much more quickly and even create solutions to problems that may not be prevalent issues yet” (Mudge 1). The standards expect that students will be prepared to collaborate in college and careers, so key elements of collaboration in those settings—in-person or virtual—need apply or be simplified to K-6 collaborative environments. This section also analyzes a case study experiment on young children about how technology functionality and design enables, encourages, or enforces collaboration.
Next, this thesis reviews three case studies that represent evolution in our understanding of technology’s role as a support system in teaching and learning collaboration. The first case study shows how simple handheld devices assisted in correcting weaknesses in a variety of collaborative and organizational skills. The second study utilizes interactive tabletop technology to realize the idea of tracking collaborative ability in real time through synchronized audio and touch recording. Finally, researchers assess the effectiveness of one student to one device (1:1) initiatives by gathering student-reported data before and after the program’s implementation, which largely speak to the direction of many schools’ technology strategies.
To supplement all of the secondary research above, the researcher of this thesis conducted interviews with nine K-6 teachers to gather their insights on collaboration and how they facilitate it. They explain how they use technology in their classroom to enhance the learning environment. Additionally, they give opinions on what could be done to make collaboration more easily taught and facilitated, as well as what would better develop their students’ collaborative skills.
The compilation of this information then leads to implications of what needs to be present, from a technology standpoint, to more effectively teach collaborative skills to our schoolchildren. This includes a brief industry analysis of a program that already exists, as well as recommendations for new technology that considers the research conducted throughout the paper. Another implication addressed centers on the instruction and facilitation of technology and the digital divide that can result from varying competency among teachers, which brings to light the need for proper technology development programs for educators.
ContributorsPetrovich, Nicholas Hugh (Author) / Ostrom, Amy (Thesis director) / Ostrom, Lonnie (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor) / Department of Management (Contributor) / School of Film, Dance and Theatre (Contributor)
Created2014-05
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Description
Scottsdale Ranch Animal Hospital (SRAH) is a well-established veterinary clinic co-owned by Dr. John Nick and Dr. Richard Stolper that is located in Scottsdale, Arizona. The hospital’s mission is to provide, “the highest quality medical, surgical, educational, boarding and grooming services available. We strive for the highest level of integrity

Scottsdale Ranch Animal Hospital (SRAH) is a well-established veterinary clinic co-owned by Dr. John Nick and Dr. Richard Stolper that is located in Scottsdale, Arizona. The hospital’s mission is to provide, “the highest quality medical, surgical, educational, boarding and grooming services available. We strive for the highest level of integrity and compassion in our interaction with our patients and their human pets” (“Welcome to Scottsdale Ranch Animal Hospital”).

The purpose of this report is to analyze the current market position of Scottsdale Ranch Animal Hospital, and make appropriate marketing recommendations and strategies for implementation. Managerial goals include increasing customer retention and growing its customer base in order to generate new revenue.

The analysis conducted includes reviewing the external environment, internal environment, and market opportunities. Notable industry and environmental trends include: laws regarding bans on the sale of commercially bred pets, an overall increase in national pet spending, declining feline veterinary visits over the last few years, a cultural trend emphasizing spending on luxury pet goods and services, and a significant level of local competition that has similar service offerings.

Notable internal strengths include: the prime geographical location of SRAH in a pet-friendly and wealthy community, multiple service offerings available, the quality of veterinary staff, a loyal clientele, and a “blank slate” in terms of marketing. However, internal weaknesses include: outdated equipment and technology, a lack of marketing efforts and a weak online presence, poor management, human resource issues and little employee accountability, and poor financial conditions as a result of high levels of debt between the practice and building.

Partway through this project, SRAH decided to sell its practice to PetVet Care Centers, a company specialized in acquiring animal hospitals in order to grow a national veterinary network. PetVet took over ownership in March of 2014, and has already begun to address the critical managerial and financial problems at SRAH. Thus, the following recommendations are made to the new owners specifically regarding building an integrated marketing campaign. The limitation, however, is that PetVet’s marketing budget is unknown at the time of this report.

Based on SRAH’s precarious position in the marketplace, it is recommended that the practice focus on client retention, capturing first time visits by creating a strong online presence, and capturing first time visits by targeting new customer segments. Client retention strategies are as follows:
• Push email sign ups for online Pet Portal. Goal is to improve the percentage of clients signed up from 36% to 43% by the end of the 2014 fiscal year (approximately 450 new sign ups).
• Specifically create policies regarding behavior in employee-client interactions.
• Include a summary sheet detailing services received and veterinarian recommendations to be given with discharge paperwork.
• Implement callbacks within 24 hours of a patient surgery to be performed by vet techs
• Create specialized goodie bags for surgeries or boarding stay. Example would be a boarding goodie bag that contains treats, toys, and a personalized “thank you for staying with us” card.
• Bundling services to create preventative care packages. Canine Junior and Senior Wellness packages could result in additional $31,000+ in revenue each year.

Strategies centered on capturing first time visits through creating a strong online presence include:
• Hiring CyberMark for its regional SEO services to improve SRAH’s ranking in search engine results.
• Switching to a new website producer to allow for greater flexibility and autonomy in managing SRAH’s website. It is suggested that PetVet consider IDEXX or CyberMark for this service.

Lastly, strategies centered on capturing first time visits by targeting new customer segments are as follow:
• Purchasing a direct mail list from DirectMailTools.com, that specifies Scottsdale homeowners or renters, who own a cat or dog, and have lived in their place of residency for less than a year.
• Consider converting breed specific groups as a long-term goal, though no immediate action is suggested.
ContributorsStolper, Samantha Lynn (Author) / Ostrom, Amy (Thesis director) / Denning, Michael (Committee member) / Barrett, The Honors College (Contributor) / Department of Marketing (Contributor)
Created2014-05