Matching Items (9)
Description
The tendency for psychopathology to aggregate within families is well-documented, though little is known regarding the level of specificity at which familial transmission of symptomology occurs. The current study first tested competing higher-order structures of psychopathology in adolescence, indexing general and more specific latent factors. Second, parent-offspring transmission was tested for broadband domain specificity versus transmission of a general liability for psychopathology. Lastly, genetic and environmental mechanisms underlying the familial aggregation of psychopathology were examined using nuclear twin-family models. The sample was comprised of five hundred adolescent twin pairs (mean age 13.24 years) and their parents drawn from the Wisconsin Twin Project. Twins and parents completed independent diagnostic interviews. For aim 1, correlated factors, bifactor, and general-factor models were tested using adolescent symptom count data. For aim 2, structural equation modeling was used to determine whether broadband domain-specific transmission effects were necessary to capture parent-offspring resemblance in psychopathology above and beyond a general transmission effect indexed by the latent correlation between a parental internalizing factor and offspring P-factor. For aim 3, general factor models were fitted in both generations, and factor scores were subsequently extracted and used in nuclear twin-family model testing. Results indicated that the bifactor model exhibited the best fit to the adolescent data. Familial aggregation of psychopathology was sufficiently accounted for by the transmission of a general liability. Lastly, the best fitting reduced nuclear twin-family model indicated that additive genetic, sibling-specific shared environmental, and nonshared environmental influences contributed to general psychopathology. Parent-offspring transmission was accounted for by shared genetics only, whereas co-twin aggregation was additionally explained by sibling-specific shared environmental factors. Results provide novel insight into the specificity and etiology of the familial aggregation of psychopathology.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Doane, Leah D (Committee member) / Arizona State University (Publisher)
Created2019
Description
The parent-child relationship is one of the earliest and most formative experiences for social and emotional development. Synchrony, defined as the rhythmic patterning and quality of mutual affect, engagement, and physiological attunement, has been identified as a critical quality of a healthy mother-infant relationship. Although the salience of the quality of family interaction has been well-established, clinical and developmental research has varied widely in methods for observing and identifying influential aspects of synchrony. In addition, modern dynamic perspectives presume multiple factors converge in a complex system influenced by both nature and nurture, in which individual traits, behavior, and environment are inextricably intertwined within the system of dyadic relational units.
The present study aimed to directly examine and compare synchrony from three distinct approaches: observed microanalytic behavioral sequences, observed global dyadic qualities, and physiological attunement between mothers and infants. The sample consisted of 323 Mexican American mothers and their infants followed from the third trimester of pregnancy through the first year of life. Mothers were interviewed prenatally, observed at a home visit at 12 weeks postpartum, and were finally interviewed for child social-emotional problems at child age 12 months. Specific aspects of synchrony (microanalytical, global, and physiological) were examined separately as well as together to identify comparable and divergent qualities within the construct.
Findings indicated that multiple perspectives on synchrony are best examined together, but as independent qualities to account for varying characteristics captured by divergent systems. Dyadic relationships characterized by higher reciprocity, more time and flexibility in mutual non-negative engagement, and less tendency to enter negative or unengaged states were associated with fewer child social-emotional problems at child age 12 months. Lower infant cortisol was associated with higher levels of externalizing problems, and smaller differences between mother and child cortisol were associated with higher levels of child dysregulation. Results underscore the complex but important nature of synchrony as a salient mechanism underlying the social-emotional growth of children. A mutually engaged, non-negative, and reciprocal environment lays the foundation for the successful social and self-regulatory competence of infants in the first year of life.
The present study aimed to directly examine and compare synchrony from three distinct approaches: observed microanalytic behavioral sequences, observed global dyadic qualities, and physiological attunement between mothers and infants. The sample consisted of 323 Mexican American mothers and their infants followed from the third trimester of pregnancy through the first year of life. Mothers were interviewed prenatally, observed at a home visit at 12 weeks postpartum, and were finally interviewed for child social-emotional problems at child age 12 months. Specific aspects of synchrony (microanalytical, global, and physiological) were examined separately as well as together to identify comparable and divergent qualities within the construct.
Findings indicated that multiple perspectives on synchrony are best examined together, but as independent qualities to account for varying characteristics captured by divergent systems. Dyadic relationships characterized by higher reciprocity, more time and flexibility in mutual non-negative engagement, and less tendency to enter negative or unengaged states were associated with fewer child social-emotional problems at child age 12 months. Lower infant cortisol was associated with higher levels of externalizing problems, and smaller differences between mother and child cortisol were associated with higher levels of child dysregulation. Results underscore the complex but important nature of synchrony as a salient mechanism underlying the social-emotional growth of children. A mutually engaged, non-negative, and reciprocal environment lays the foundation for the successful social and self-regulatory competence of infants in the first year of life.
ContributorsCoburn, Shayna Skelley (Author) / Crnic, Keith A (Thesis advisor) / Dishion, Thomas J (Committee member) / Mackinnon, David P (Committee member) / Luecken, Linda J. (Committee member) / Arizona State University (Publisher)
Created2015
Description
Pediatric chronic pain is pervasive and associated with myriad adverse consequences, yet due consideration has not been given to the mental health disturbances that often present alongside chronic pain and the etiological mechanisms that potentially underlie both. The current study examined the etiology underlying chronic pain and internalizing symptomology in middle childhood, considering both independent and co-occurring symptom presentations. Phenotypic parent-offspring associations across chronic pain and internalizing symptomology were also examined. Lastly, nuclear twin family models were tested to determine the extent to which genetic and environmental factors underlie parent-offspring transmission. The sample comprised 795 children (399 families; Mage= 9.7 years; SD = 0.92) and their parents drawn from the Arizona Twin Project. Results indicated that chronic pain was highly heritable (78%), whereas internalizing symptomology was modestly heritable (32%) and further subject to moderate shared environmental influence (50%). Moreover, 9% of the variance in chronic pain was explained by additive genetic factors shared with internalizing symptomology. Maternal chronic pain and internalizing symptomology were positively associated with both child chronic pain and internalizing symptomology. The association between maternal chronic pain and child chronic pain was more pronounced for girls than boys, whereas the association between maternal internalizing symptomology and child internalizing symptomology was more pronounced for boys than girls. Paternal chronic pain was not significantly associated with child chronic pain but was unexpectedly associated with lower child internalizing symptomology. The negative association between paternal chronic pain and child internalizing symptomology was more pronounced for boys than girls. Paternal internalizing symptomology was not significantly associated with child chronic pain but was positively associated with child internalizing symptomology. Lastly, the best fitting reduced nuclear twin family models for both chronic pain and internalizing symptomology retained additive genetic, sibling-specific shared environmental, and nonshared environmental parameters, where parent-offspring transmission was solely explained by shared genetics and sibling-specific shared environmental factors further accounted for co-twin resemblance. Results provide novel insight into common liabilities underlying chronic pain and internalizing symptomology in middle childhood, parent-offspring associations across chronic pain and internalizing symptomology, and the etiological mechanisms that explain symptom aggregation across generations.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Davis, Mary (Committee member) / Su, Jinni (Committee member) / Arizona State University (Publisher)
Created2021
Description
In 2011, fetal researcher Vivette Glover published “Annual Research Review: Prenatal Stress and the Origins of Psychopathology: An Evolutionary Perspective,” hereafter, “Prenatal Stress and the Origins of Psychopathology,” in the Journal of Child Psychology and Psychiatry. In that article, Glover explained how an evolutionary perspective may be useful in understanding the effects of fetal programming. Fetal programming is a hypothesis that attempts to explain how factors during pregnancy can affect fetuses after birth. Researchers associate exposure to prenatal stress, or stress experienced before birth, with an increased likelihood of some mental disorders. Glover states that such outcomes may be traced back to a fetus’s response to stress during pregnancy, and that those outcomes may have been beneficial in the past. By taking an evolutionary approach toward understanding mental disorders, Glover provided insights for studying the lasting effects of maternal stress during pregnancy on children’s mental health.
ContributorsKeller, Carrie (Author) / Darby, Alexis (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2020-05-02
Description
Stress in individuals presents in various forms and may accumulate across development to predict maladaptive physical and psychological outcomes, including greater risk for the onset of internalizing symptoms. Early life stress, daily life experiences, and the stress response of the hypothalamic-pituitary-adrenal (HPA) axis have all been examined as potential predictors of the development of psychopathology, but rarely have researchers attempted to understand the covariation or interaction among these stress domains using a longitudinal design when looking at the influence of stress on internalizing psychopathology. Further, most research has examined these processes in adulthood or adolescence with much less attention given to the influence of these dynamic stress pathways in childhood. Guided by the biopsychosocial model of stress, this study explored early life stress, daily life stress, diurnal cortisol (cortisol AM slope), and internalizing symptoms in a racially/ethnically and socioeconomically diverse sample of twins participating in an ongoing longitudinal study (N=970 children; Arizona Twin Project; Lemery-Chalfant et al. 2013). An additive model of stress and a stress sensitization framework model were considered as potential pathways of stress to internalizing symptoms in middle childhood. Based on a thorough review of relevant literature, it was expected that each stress indicator would individually predict internalizing symptoms. It was also predicted that early life stress would moderate the associations between diurnal cortisol and internalizing symptoms, as well as daily life stress and internalizing symptoms. Multilevel modeling analyses showed that early life stress and cortisol AM slope, but not daily life stress, predicted internalizing symptoms. Early life stress did not moderate the associations between daily life stress and internalizing symptoms or cortisol AM slope and internalizing symptoms. Results support independent additive contributions of both physiological stress processes and early life parental stressors in the development of internalizing symptoms in middle childhood. Future investigation is needed to better understand the sensitizing effects of early parental life stress during this developmental stage.
ContributorsLecarie, Emma (Author) / Doane, Leah (Thesis advisor) / Davis, Mary (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2020
Description
The number of children currently experiencing a psychopathological disorder is growing quickly. It is essential to identify different causes of this to understand better how to prevent psychopathology in children. Prior research has shown that different emotion dynamics between the parent and child, like rigidity, flexibility, or synchrony, have been found to be associated with psychopathology. Synchrony or the matching of positive emotions in a dyad has been found to be protective against symptoms of psychopathology for children. In addition, flexibility, or the number of emotion transitions between a dyad, has also been shown to be protective against symptoms of psychopathology, although rigidity or fewer emotion transitions in a dyad has been predictive of psychopathology. However, this research has been almost entirely focused on infants and toddlers as well as adolescents, with little research being done on synchrony, rigidity, and flexibility in middle childhood. This study aimed to identify whether synchrony, rigidity, and flexibility are predictive or protective of internalizing, externalizing, and ADHD symptoms of psychopathology in middle childhood. Data was collected from a sample of 762 ethnically diverse children from the Arizona Twin Project that were assessed at ages 9 (Mage=9.71, SD=.93) and 11 (Mage=11.65, SD=1.04). Children and their parents were examined when the child was 9 during a video-recorded discussion task to determine rigidity, flexibility, and synchrony that was coded by iMotion Affectiva. Internalizing, externalizing, and ADHD symptoms of psychopathology were measured at ages 9 and 11 both through parent-report and child report. Results found that during a conflict-based discussion, synchrony and negative co-regulation between the parent and child were protective against internalizing, externalizing, and ADHD symptoms of psychopathology both concurrently and longitudinally. Rigidity and flexibility between the parent and child were not found to be associated with psychopathology. These
findings can help inform future parenting programs or influence parent child interactions by teaching the importance of using positive emotions during negative conversations with parents.
ContributorsSather, Amanda (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Doane, Leah (Committee member) / Benitez, Viridiana (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / Department of Psychology (Contributor)
Created2022-12
Description
Among children in the United States, there is a high prevalence of psychopathology. Understanding what contributes to the development of these disorders in early adolescence and late childhood is key to informing intervention efforts. This study aimed to understand the impacts of economic and social stress on the development of internalizing and externalizing psychopathology in children. Additionally, with the knowledge that supportive adult relationships can buffer psychopathology impacts, it sought to uncover if supportive sibling relationships can alter the relationship between stress and psychopathology. Data was collected through both home visits and online questionnaires as part of the Arizona Twin Project. The sample of the twins at eight years old included 355 families (M = 8.43 years, SD = .68) and 709 twins (MZ = 29.9%, same-sex DZ = 37.8%, opposite-sex DZ = 31.7%, and unknown zygosity = 0.6%) with ethnically and socioeconomically diverse backgrounds. Families were followed longitudinally with annual assessments at ages 9, 10, and 11. Our results showcased a significant positive relationship between economic stress and the development of internalizing and externalizing psychopathology symptoms in children. Our social stress indicators were categorized into family stress and negative parenting constructs. It was observed that family stress was linked to an increase in both internalizing and externalizing symptoms. However, when it came to parenting behaviors, no significant associations were identified with the development of either externalizing or internalizing symptoms in our study. In terms of the potential moderating effects of a positive sibling relationship, no significant results were found. Ultimately, our study showcases the adverse impact of stress on children and early adolescents. Further research on the impacts of the relationship between siblings can help us to better understand the dynamics in the home as a whole and explore whether relationships beyond those with supportive adults can contribute to resilience in children. This knowledge may guide interventions and preventive measures aimed at mitigating the effects of psychopathology in young individuals.
ContributorsHammond, Arden (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Ostner, Savannah (Committee member) / Pickett, Janna (Committee member) / Barrett, The Honors College (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2023-12
Description
Approximately 20% of youth experience mental health problems (Vasileva et al., 2021), and dimensions of early childhood temperament, specifically negative affectivity and effortful control, predict later mental health (Rothbart, 2007). Examining temperament using person-centered methods, particularly in stressful contexts, may improve our understanding of vulnerability to adolescent emotional problems. The current study examined whether specific patterns, or types, of infant temperament longitudinally predicted adolescent anxiety and depression symptoms and whether family relationship stress moderated this association. We hypothesized that infants with a Negative Dysregulated temperament would experience higher anxiety and depression symptoms in later childhood compared to those with a Typical Expressive temperament, and that family relationship stress would exacerbate this link. In an ongoing-longitudinal study of families with twins (N=563, 51% female, 29.8% Hispanic/Latinx, 58.4% White; Lemery-Chalfant et al., 2019), primary caregivers (PCs) reported on infant temperament at 12 months (IBQ; Gartstein & Rothbart, 2003, α=.74-.90). In a prior study (Murillo et al., 2023), latent profile analysis yielded three infant temperament types: Negative Dysregulated, Positive Well-Regulated, and Typical Expressive. PCs reported on partner strain (PSS; Schuster, Kessler, & Asseltine, 1990, α=.87) and family conflict (FCS; Porter & O’Leary, 1980, α=.80) at age 8 and a composite of these two measures represented Family Relationship Stress (r = .689). Confirmatory factor analysis was used to form Depression and Anxiety outcome composites based on PC (4 reports), secondary caregiver (2 reports), teacher (2 reports), and self-report (3 reports) measures of depression and anxiety symptoms collected from ages 8-11 (HBQ, Armstrong & Goldstein, 2003; BPI, Measelle et al., 1998, all α’s > .80). We randomly selected one twin from each pair and conducted regression analyses, and then used the second twin for an internal replication. Family relationship stress had a significant main effect on both anxiety and depressive symptoms. The Negative Dysregulated temperament type did not predict anxiety and depression at ages 8-11, however, it interacted with family relationship stress to predict anxiety and depression in 1 of 2 samples. When family relationship stress was low, the Negative Dysregulated type was significantly associated with higher anxiety and depression outcomes compared to the Typical Expressive type, and high family relationship stress was significantly associated with lower depression outcomes. Elucidating these longitudinal relations is important for informing early intervention and reducing the burden of adolescent psychopathology.
ContributorsSingh, Ajuni (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Corbin, William (Committee member) / Davis, Mary (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor)
Created2023-12
Description
Drawing upon the theoretical framework of Cooley’s (1902) “looking-glass self” model, the current study examined how affective dimensions of parenting in adolescence contribute to psychopathology in early adulthood through the mediating mechanism of authenticity – one’s level of comfort with being oneself. Using latent profile analysis (LPA), a three-class solution was identified, classifying inadequate, adequate, and optimal profiles of parenting in adolescence. Class membership was used in a multilevel mediation structural equation model to examine longitudinal links with authenticity and psychopathology (e.g., internalizing, externalizing, and substance abuse disorders) in early adulthood. Results demonstrated that optimal compared to inadequate parent-adolescent relationship quality was directly linked to higher levels of authenticity, which in turn, was directly linked to lower levels of all forms of psychopathology in early adulthood. Results also indicated that authenticity fully mediated the link between profiles of parent-adolescent relationship quality (e.g., grade 12) and internalizing, externalizing, and substance abuse disorders in early adulthood (e.g., four years post-college). In conclusion, the current study demonstrated the influence of affective dimensions of parenting profiles in adolescence on the development of psychopathology in early adulthood via the mediating mechanism of authenticity. Moreover, findings from the current study suggest that authenticity is a critical feature shared in common among various forms of psychopathology. Finally, clinical implications are discussed regarding the potential effectiveness of evidence-based psychotherapies aimed at the promotion of authenticity as a mechanism for improving mental health and well-being.
ContributorsEbbert, Ashley Marie (Author) / Infurna, Frank J (Thesis advisor) / Luthar, Suniya S (Committee member) / Grimm, Kevin J (Committee member) / Krasnow, Aaron D (Committee member) / Arizona State University (Publisher)
Created2021