Matching Items (253)
Description
Blood donations today undergo extensive screening for transfusion transmitted infections (TTI) since the discovery of the first infectious agent in the early 1900s. Nucleic Acid Testing (NAT) is a serological test used widely in disease detection. NAT is known to rapidly and effectively detect pathogenic genomic material in blood by reducing the "window period" of infection. However, NAT produces false negative results for disease positive samples posing a risk of disease transmission. Therefore, NAT is used in conjunction with the Enzyme-Linked Immunosorbent Assay (ELISA) to mitigate these risks. However, the ELISA assay also poses the same risk as NAT. This study proposes immunosignaturing as an alternative serological test that may combat this risk and investigates whether it would be more effective than other standardized serological tests in disease detection. Immunosignaturing detects antibodies by utilizing a microarray of randomized peptide sequences. Immunosignaturing provides information about an individual's immune health from the pattern of reactivity of antibody-peptide binding. Unlike ELISA and NAT, immunosignaturing can be programmed to detect any disease and detect multiple diseases simultaneously. Using ELISA, NAT, and immunosignaturing, immune profiles of asymptomatic patients were constructed for 10 different classes of blood borne diseases. A pattern of infection was identified for each disease and the sensitivity and specificity of these assays were assessed relative to each other. Results indicate that immunosignaturing can be a viable diagnostic tool in blood testing. Immunosignatures demonstrated increased sensitivity and specificity compared to ELISA and NAT in discerning disease positive and negative samples within and across different classes of disease.
ContributorsSharma, Megumi (Author) / McFadden, Grant (Thesis director) / Nickerson, Cheryl (Committee member) / Green, Alex (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Human trafficking is not only a social injustice, but also a major global health problem, that our communities cannot ignore. Despite the common misconception that trafficking is only seen in foreign countries or is only related to immigrants, the U.S. is known to be a major trafficking market and destination, with trafficking reported in all 50 states (Bladwin et al., 2011; Shandro et al., 2016; Dovydaitis, 2010). Although trafficking victims are unlikely to have appropriate access to health care, as much as 80% of sex trafficking victims have reported that they encountered a medical professional while under their traffickers' control and went unidentified at the time (Baldwin et al., 2011; Shandro et al., 2016). This exemplifies a serious missed opportunity for intervention. Health care providers should be prepared to identify and care for victims of trafficking as part of their routine clinical practice. This thesis aims to describe trafficking victims' encounters in U.S. health care settings, to assess health care professionals' and students' awareness, knowledge, and beliefs on trafficking, to examine the impact of an educational intervention on this populations' knowledge/belief changes, and to ultimately spread education about this issue to a wide array of communities.
ContributorsFelix, Kaitlyn Nicole (Author) / Larkey, Linda (Thesis director) / Calvin, Samantha (Committee member) / School of Nutrition and Health Promotion (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This project modifies an existing theory-based culturally responsive nutrition and physical activity curriculum designed for early adolescent Hispanic children. Modifications to the Salud con Sabor Latino para los Ninos (SSLN) curriculum, originally designed for adolescents, include didactic content and activities which are evidence-based and age appropriate for younger children (second to fourth grade). Using a community based participatory research approach, culturally responsive and developmentally cognizant modifications were made based on child development theories, social behavior theory, and evidence of successful obesity interventions among this age group. The end goal is to assist the community partner, Esperança, and provide an opportunity to impact obesity rates in this high risk population.
The goal of the updated eight session SSLN program is to decrease BMI, increase nutritional knowledge, and improve attitude and behavior towards nutrition and physical activity in Hispanic school-aged children. After meeting with Esperança to identify which elements of the curriculum needed modification, an extensive literature review was conducted to identify new and relevant research appropriate to the modifications. Integrating child development theories, social behavior theory, and results from earlier successful obesity intervention programs, curriculum sessions will be condensed and modified using a community base participatory research approach. Once edits to the curriculum are completed and approved, Esperança will implement the newly modified curriculum, and evaluate the success of the curriculum changes.
The final project is composed of a condensed, theory-based, culturally responsive, and developmentally age appropriate eight session curricula that will educate Hispanic school-aged children on nutrition and physical activity.
The goal of the updated eight session SSLN program is to decrease BMI, increase nutritional knowledge, and improve attitude and behavior towards nutrition and physical activity in Hispanic school-aged children. After meeting with Esperança to identify which elements of the curriculum needed modification, an extensive literature review was conducted to identify new and relevant research appropriate to the modifications. Integrating child development theories, social behavior theory, and results from earlier successful obesity intervention programs, curriculum sessions will be condensed and modified using a community base participatory research approach. Once edits to the curriculum are completed and approved, Esperança will implement the newly modified curriculum, and evaluate the success of the curriculum changes.
The final project is composed of a condensed, theory-based, culturally responsive, and developmentally age appropriate eight session curricula that will educate Hispanic school-aged children on nutrition and physical activity.
ContributorsTooms, Allison Jayce (Author) / Stevens, Carol (Thesis director) / Beals, Jacqueline (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Procedural guidelines are used to teach nursing students the hands-on skills needed to care for patients in the clinical setting. These guidelines are presented to nursing students during their experiential lab courses throughout their education. This thesis paper describes the development of two procedural guidelines: one for administering intravenous medication through a primary line, and one for administering intravenous medication through a secondary line. These guidelines specifically state the required steps necessary to complete the respective tasks. They are written to promote safety and represent the best evidence-based practices. The goals of these guidelines are to function as teaching tools for faculty and study tools for students. They were provided to Arizona State University nursing students, currently in the College of Nursing and Health Innovation bachelors program, who had previously learned how to administer intravenous medication through a primary and secondary line without the help of any written procedure. After the summer break of 2017, an entire cohort of students refreshed their skills with the help of the procedural guidelines and found them to be user friendly and helpful in performing the skills safely and accurately. As a result, these guidelines will be used as an educational tool for future nursing students. While procedural guidelines are effective at teaching a skill for the first time, other forms of guides should be available as a reference for nurses who have already mastered the skill. The concept of checklists and their viability to promote safety and adherence to facility policies in various healthcare institutions are also discussed in this paper. Research shows that checklists have the capability to improve safety and work well for nurses who have fallen into complacency (Wiener, 1981).
ContributorsCole, Grace (Author) / Peterson, Katherine (Thesis director) / Markiewicz, Katherine (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The period of time between birth and 24 months of age is a sensitive period for infant growth, and adequate nutrition is vitally important. In this study, 150 Mexican-American mother-and-child pairs (N = 300) were periodically surveyed over the course of 36 months for demographics, financial status, and feeding practices to understand the feeding methods of Mexican-American families and any relations they may have to the weight and growth of developing infants. Results found that formula feeding had higher rates of usage and duration than breastfeeding, while solid foods were largely introduced at the recommended ages. At one year of age, the infants were predisposed towards overweight and obesity with a high maternal BMI, suggesting that breastfeeding practices were not fully utilized. However, the data did not differentiate between formula and breast milk when both were used at any specific age, making it difficult to determine how long infants were exclusively breastfed and how that would impact their growth.
ContributorsCorsi, Marisa Kalani Nicole (Author) / Reifsnider, Elizabeth (Thesis director) / Thatcher, Craig (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This paper investigates how stress in parents is affected by their child's Attention-Deficit/Hyperactivity Disorder (ADHD). The purpose of this paper is to identify common stressors for parents of children with ADHD, as well as to determine what parents need from healthcare providers to mediate this stress. A survey was developed to identify sources of stress, consequences of parental stress, parental coping methods, resources provided by their healthcare provider that have been helpful, along with what they feel that they need from their healthcare providers in order to better support themselves and their family. Participants were composed of members of Facebook support groups for parents of children with ADHD. Major findings of this study include: parents experience the most stress when dealing with their child's oppositional and aggressive behaviors; parents frequently experience disruption in their marital relationship; and parents perceive that they receive little health care resources that are helpful for themselves, their child, and their family overall.
ContributorsHui, Natasha Faith (Author) / Sayles, Judy (Thesis director) / Beals, Jacqueline (Committee member) / Caterino, Linda (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The objective of the present study was to investigate differences in traditional and non-traditional cardiovascular disease (CVD) risk factors between Asian and non-Hispanic White young adults. The burden of CVD varies by racial/ethnic group. Traditional risk factors that increase the likelihood of developing CVD include smoking, alcohol, physical inactivity, obesity, diabetes, high cholesterol, and high blood pressure. Suboptimal sleep is known to be a non-traditional risk factor for poor overall health, CVD risk factors, and CVD. The present study was an investigation of a cross-sectional, screening survey used for a larger community-based study on sleep and cardiovascular health. The unadjusted results examining differences in traditional CVD risk factors indicated that Asian participants were less likely to report alcohol use compared to non-Hispanic White participants. For non-traditional CVD risk factors, Asians were less likely to report experiencing sleep-related fatigue or malaise, attention impairment, daytime sleepiness, reduced motivation or energy, or concerns about their sleep compared to non-Hispanic White participants. Multivariate-analyses were conducted adjusting for sex and age. The adjusted results indicated that the Asian participants were less likely to report alcohol consumption, regular engagement in exercise, engagement in hard intensity exercise, concerns with sleep quality, and sleep difficulty-related fatigue, attention impairment, daytime sleepiness, reduced motivation, and were more likely to be obese compared to non-Hispanic White participants. The results may help guide cardiovascular prevention education provided to these groups. The data indicate the need for further longitudinal research studies on non-traditional CVD risk factors like sleep by ethnicity/race.
ContributorsSpoehr, Natalie Jane (Author) / Petrov, Megan (Thesis director) / Shin, Chanam (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
Purpose: The purpose of this study was to determine the efficacy of a yoga intervention for adolescents suffering from depression. Secondary results regarding the viability of yoga as an intervention for increasing self-esteem and decreasing anxiety were also explored.
Methods: Using PubMed, Medline, and CINAHL the search terms adolescents, depression, and yoga were searched for related articles. Articles were then excluded or included based on certain criteria. Focus was placed on articles written within the last 10 years as well as studies done on children within 10-19 years of age. Final articles underwent extraction for relevant information and comparisons were drawn between the studies.
Results: Final exclusion lead to a total of 5 suitable studies. Studies varied in styles of yoga performed and measurement scales used to assess depression. Populations of adolescents varied significantly as well. The majority of these studies showed significant improvement in depression symptoms when measuring from pre to post intervention. Similar improvements were also noted in anxiety symptoms and low self-esteem.
Conclusion: Data gathered indicated that yoga serves a suitable intervention for decreasing depression symptoms in adolescents. Additionally, there seems to be promising results regarding the viability of yoga as an intervention for decreasing symptoms of anxiety and increasing self-esteem. Despite, current promising results, there is need for more research to affirm the findings found in these articles to determine the long term effects of yoga interventions.
Methods: Using PubMed, Medline, and CINAHL the search terms adolescents, depression, and yoga were searched for related articles. Articles were then excluded or included based on certain criteria. Focus was placed on articles written within the last 10 years as well as studies done on children within 10-19 years of age. Final articles underwent extraction for relevant information and comparisons were drawn between the studies.
Results: Final exclusion lead to a total of 5 suitable studies. Studies varied in styles of yoga performed and measurement scales used to assess depression. Populations of adolescents varied significantly as well. The majority of these studies showed significant improvement in depression symptoms when measuring from pre to post intervention. Similar improvements were also noted in anxiety symptoms and low self-esteem.
Conclusion: Data gathered indicated that yoga serves a suitable intervention for decreasing depression symptoms in adolescents. Additionally, there seems to be promising results regarding the viability of yoga as an intervention for decreasing symptoms of anxiety and increasing self-esteem. Despite, current promising results, there is need for more research to affirm the findings found in these articles to determine the long term effects of yoga interventions.
ContributorsMenon, Pranav (Co-author) / Giedraitis, Frances (Co-author) / Larkey, Linda (Thesis director) / Calvin, Samantha (Committee member) / W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The number of individuals born with the neural tube defect, spina bifida, is still widespread here in the United States. To briefly explain, spina bifida is a birth defect where the baby's vertebrae does not fully enclose the spinal cord. There are specifically four types of spina bifida, with varying degrees of severity. This severity can range from no symptoms to complete paralysis below the cleft area. To put this issue into perspective, approximately 166,000 individuals in the United States, today, are affected by spina bifida (National Health Institute, 2017). The purpose of the study is to determine if there is a knowledge discrepancy of health care needs between individuals who have Spina Bifida and ASU students studying a health profession. This will determine if there is a need to improve health care education of students, professionals, and members of a spina bifida association in respect to spina bifida. Not only that, this study will also identify if there is a need to increase awareness and prevention of spina bifida in the community to improve health outcomes for those affected by spina bifida. A total of 136 participants were studied with the 32-question survey. It was found, through the survey, that there was a knowledge mismatch between spina bifida members and ASU students who were studying a health profession. This knowledge mismatch was also compared with how well they answered the various questions as a group.
ContributorsLerias, Antoni Capacio (Author) / Lalley, Cathy (Thesis director) / Milowski, Meredith (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The purpose of this study was to explore the effects of a four-week martial arts program implemented once a week on children diagnosed with attention-deficit hyperactivity disorder (ADHD) between the ages of four and seven. This was a single group, pre- and post-intervention assessment pilot study. The total sample of the study was four children (n=4) and the martial arts classes were based on the Duke Kenpo Little Tiger Program by Jonathan Duke of Mesa, Arizona. Change was measured using the Behavior Rating Inventory of Executive Function, 2nd edition (BRIEF-2) parental form and participants were encouraged to record at-home practice. Data were collected pre-intervention and four weeks afterwards. Limitations included small sample size, measurement limitation (e.g., ceiling effect), data based on parental report, a short intervention period, potential instructor bias, and uneven gender distribution. Given the small sample size (n=4), this study did not complete statistical analysis and alternatively described the changing patterns of the participant's ADHD symptoms from BRIEF-2 measures pre and post intervention. The results of this study could not generate the power to detect significance to state significant implications. However, the trends suggested that some participants declined in executive function in certain areas (e.g., task-monitoring and planning) and improved in other areas (e.g., working memory and organization of materials). All participants demonstrated improvement within the cognitive (CRI) scale of the BRIEF-2 and future studies may explore the potential for martial arts interventions in children under seven as a means to improve the cognitive aspect of executive function development. In addition, future studies may consider exploring the role of frequency versus time for at-home martial arts practice for children with ADHD under the age of seven.
ContributorsNaylor, Takara (Author) / Larkey, Linda (Thesis director) / Noah, Aggie (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12