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Widespread quorum-sensing (QS) enables bacteria to communicate and plays a critical role in controlling bacterial virulence. However, effects of promiscuous QS crosstalk and its implications for gene regulation and cell

Widespread quorum-sensing (QS) enables bacteria to communicate and plays a critical role in controlling bacterial virulence. However, effects of promiscuous QS crosstalk and its implications for gene regulation and cell decision-making remain largely unknown. Here we systematically studied the crosstalk between LuxR/I and LasR/I systems and found that QS crosstalk can be dissected into signal crosstalk and promoter crosstalk.

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  • 2014-12-18
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    Wu, Fuqing, Menn, David J., & Wang, Xiao (2014). Quorum-Sensing Crosstalk-Driven Synthetic Circuits: From Unimodality to Trimodality. CHEMISTRY & BIOLOGY, 21(12), 1629-1638. http://dx.doi.org/10.1016/j.chembiol.2014.10.008

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