Embryo Project Encyclopedia Articles

The birth control pill, more commonly known as "the pill" is a form of contraception taken daily in pill form and consisting of synthetic hormones formulated to prevent ovulation, fertilization, and implantation of a fertilized egg. The US Food and Drug Administration (FDA) approved the first birth control pill, Enovid, in June 1960. It was the first contraceptive pill marketed worldwide. Since then a number of different pills have been developed, which differ in hormone type and dosage, and whether they contain one hormone (the minipill) or two (the combination pill). The development of an effective oral contraceptive was an enormous step in the reproductive rights movement, as contraceptives provided women and couples a means of planning families and limiting the number of children they had.

When James Thomson of the University of Wisconsin announced in 1998 that he had derived and cultured human embryonic stem cells(hESCs), Americans widely believed-and accepted-that stem cells would one day be the basis of a multitude of regenerative medical techniques. Researchers promised that they would soon be able to cure a variety of diseases and injuries such as cancer, diabetes, Parkinson's, spinal cord injuries, severe burns, and many others. But it wasn't until January 2009 that the Food and Drug Administration approved the first human clinical trials using hESCs. The trials were put on hold in August of 2009 before they were ever begun. After more than a decade of being promised curative stem cell therapy, many people have been unwilling to wait for American doctors to provide stem cell treatments. Some people have opted not to wait or rely on other treatments, and have chosen to receive stem cell therapy from international institutions. This phenomenon has been dubbed stem cell tourism, and it has garnered much media attention, both in support and in opposition.

Teratomas are embryonal tumors that normally arise from germ cells and are typically benign. They are defined as being composed either of tissues that are foreign to the area in which they form, or of tissues that derive from all three of the germ layers. Malignant teratomas are known as teratocarcinomas; these cancerous growths have played a pivotal role in the discovery of stem cells. "Teratoma" is Greek for "monstrous tumor"; these tumors were so named because they sometimes contain hair, teeth, bone, neurons, and even eyes. Teratomas have been medical curiosities for centuries, though it wasn't until the 1960s that significant research into mice teratomas elucidated not only what these strange growths were, but also how germinal cells should normally function.

Abortion is the removal of the embryo or fetus from the womb, before birth can occur-either naturally or by induced labor. Prenatal development occurs in three stages: the zygote, or fertilized egg; the embryo, from post-conception to eight weeks; and the fetus, from eight weeks after conception until the baby is born. After abortion, the infant does not and cannot live. Spontaneous abortion is the loss of the infant naturally or accidentally, without the will of the mother. It is more commonly referred to as miscarriage. Induced abortion is the deliberate removal of a developing infant to end a pregnancy.

In 1927, the US Supreme Court case Buck v. Bell set the legal precedent that states may sterilize inmates of public institutions because the court argued that imbecility, epilepsy, and feeblemindedness are hereditary, and that the inmates should be prevented from passing these defects to the next generation. On 2 May 1927, in an eight to one decision, the US Supreme Court ordered that Carrie Buck, feebleminded daughter of a feebleminded mother and herself the mother of a feebleminded child, be sterilized under the 1924 Virginia Eugenical Sterilization Act. Buck v. Bell determined that compulsory sterilization laws did not violate due process awarded by the 14th Amendment to the US Constitution. It also bolstered the American eugenics movement and established legal authority for sterilizing more than 60,000 US citizens in over thirty states, until most of the practices ended in the 1970s.

In 1963, Roman Catholic fertility doctor John Rock published The Time Has Come: A Catholic Doctor's Proposals to End the Battle over Birth Control, a first-person treatise on the use of scientifically approved forms of birth control for Catholic couples. The first contraceptive pill, called Enovid, had been on the market since June 1960, and Rock was one of the leading researchers in its development. In The Time Has Come, Rock explicitly describes the arguments for and against the use of birth control from both a religious and a scientific perspective. With this work, he hoped to persuade the Roman Catholic Church that the use of a contraceptive pill was not contrary to Catholic natural law, which states that the primary function of marital sexual relations is to conceive a child. Rock lobbied for the acceptance and widespread use of contraceptive pills, which he considered to be of vital importance not only to women's reproductive health, but also to the struggle to control the world s burgeoning population.

The Roscoe B. Jackson Laboratory, known commonly in the scientific field as the Jackson Laboratory, was founded by Clarence Cook Little in May 1929. The lab has been pivotal in research with in vitro fertilization, teratomas, gene replacement therapy for birth defects, and more because its researchers have focused from the beginning on developing the mouse as a model organism. Mice were chosen by researchers at Jackson as the best available model for genetic research, and today genetically uniform strains of mice developed at the lab are used in laboratories all over the world. Located at Bar Harbor on Mount Desert Island in Maine, the Jackson Laboratory focuses today on cancer research using mouse genomics.