Embryo Project Encyclopedia Articles
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- All Subjects: Experiments
- Creators: Sunderland, Mary E.
Description
Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have identified some of the molecular mechanisms determining polarity. Recent work by his group has shown Wnt-β-catenin signaling determines whether a tail or a head will form during regeneration in planarians. This study was motivated by work Thomas Hunt Morgan conducted in the late nineteenth century. Morgan observed that during regeneration a planarian cut into rather small pieces would sometimes regenerate a head at both its anterior and posterior end rather than a head and a tail. This led Morgan to think the size of the piece must affect the regenerative process.
ContributorsSunderland, Mary E. (Author) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2010-03-15