The Embryo Project Encyclopedia (https://embryo.asu.edu) is an open-access digital encyclopedia devoted to recording and contextualizing the science of embryos, development, and reproduction. The collection of documents, images, and multimedia housed here serves as the Encyclopedia's permanent archive.

Jane Maienschein, ASU University Professor, Regents Professor, and Director of the Biology and Society Program, started the Embryo Project Encyclopedia in 2007 with support from the National Science Foundation.

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The Use of Morphine and Scopolamine to Induce Twilight Sleep

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In 1907, researchers Bernhardt Kronig and Carl Gauss combined the drugs morphine and scopolamine to induce twilight sleep in women during childbirth. Physicians in the early twentieth century in Germany used twilight sleep, Dammerschlaf, to cause women to enter a state of consciousness in which they felt no pain and…

In 1907, researchers Bernhardt Kronig and Carl Gauss combined the drugs morphine and scopolamine to induce twilight sleep in women during childbirth. Physicians in the early twentieth century in Germany used twilight sleep, Dammerschlaf, to cause women to enter a state of consciousness in which they felt no pain and did not remember giving birth. Twilight sleep was associated with increased use of forceps during delivery, prolonged labor, and increased risk of infant suffocation. Because of those disadvantages, physicians stopped using morphine and scopolamine to prevent pain during childbirth. Morphine and scopolamine were among the first anesthetics to be used during childbirth, and after physicians stopped using them, researchers searched for safer alternatives.
ContributorsCartwright, Jessica (Author) / Guerrero, Anna C. (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2019-05-02