The Embryo Project Encyclopedia (https://embryo.asu.edu) is an open-access digital encyclopedia devoted to recording and contextualizing the science of embryos, development, and reproduction. The collection of documents, images, and multimedia housed here serves as the Encyclopedia's permanent archive.

Jane Maienschein, ASU University Professor, Regents Professor, and Director of the Biology and Society Program, started the Embryo Project Encyclopedia in 2007 with support from the National Science Foundation.

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Retinoids As Teratogens

Description

Vitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial tissue. Studies have shown that an excess of vitamin A can affect embryonic development and result in teratogenesis, or the production of birth defects in a developing embryo. Excess…

Vitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial tissue. Studies have shown that an excess of vitamin A can affect embryonic development and result in teratogenesis, or the production of birth defects in a developing embryo. Excess intake of vitamin A and retinoids by pregnant women often results malformations to fetuses' skulls, faces, limbs, eyes, central nervous system. Additionally, doctors often use derivatives of vitamin A, known as retinoids, as medicine to treat a number of skin conditions and carcinomas, the most common form of human cancers.
ContributorsTantibanchachai, Chanapa (Author) / LaTourelle, Jonathan J. (Editor) / Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher) / Arizona Board of Regents (Publisher)
Created2014-02-28