Theses and Dissertations

Agenesis of the corpus callosum is the lack of the development of the corpus callosum. This condition can lead to impairments in language processing, epilepsy, and emotion and social functioning, but many individuals with this condition do not show any of these impairments. The present study investigated the connectivity of language and sensorimotor networks within an individual with agenesis of the corpus callosum using resting-state fMRI. The individual’s results were compared to those of neurotypical control subjects. It was hypothesized that the overall interhemispheric functional connectivity would be less than that of a control group in bilateral language networks, but the intrahemispheric connectivity, particularly within the sensorimotor network, would show greater functional connectivity. The results revealed significantly weaker functional connectivity in the individual with agenesis of the corpus callosum within the right ventral stream compared to the control group. There were no other significant inter or intrahemispheric differences in the functional connectivity of the language and sensorimotor networks. These findings lead us to conclude that the right hemisphere’s ventral stream perhaps relies upon connections with the left hemisphere’s language networks to maintain its typical functionality. The results of this study support the idea that, in the case of corpus callosum agenesis, the right language network may contribute differently to language processes than in neurotypical controls.

The purpose of this project is to explore the historical context and current state of prison hospice programs in the US. This objective was accomplished through an extensive review and synthesis of the relevant literature pertaining to prison hospice programs in the US. The historical increase of the incarceration rate beginning in America during the 1980’s has led to the development of more elderly prisoners than ever before in the US. As prisoners age in the US correctional system, they experience faster-than-average health decline. Mass incarceration has placed incredible strain on the correctional system to provide healthcare to the medically complex elderly inmate population. This project proposes that some of this systematic strain may be alleviated through the action of prison hospice programs. Prison hospices replace unnecessary industrial medical interventions with personalized comfort care measures and the unique service of inmate volunteers. This approach to medical care at the end of life has become the standard of care for the free population but is slower to emerge in the prison context. This project asserts that the dying US inmate population should be offered the right to a dignified death through equitable access to hospice services.

This thesis project will discuss how the three macronutrients, protein, carbohydrate and fat, benefit the body and what happens when the body is lacking in any of them. It also delves into micronutrients and supplements and how those can aid in the recovery process following an injury. Inflammation and sleep as well as mood disturbances are also explained. Meal options are available in the second half of this paper displaying pictures of nutritional meals along with their ingredients, instructions and calories. This project displays how a lack of protein can decrease muscle protein synthesis, how carbohydrate deficiency can lead to fatigue and more injury and how Omega-3 fatty acids are more beneficial than Omega-6 fatty acids. In addition, the paper discusses how vitamins, such as vitamin D and C, are important in providing bone strength and preventing excess inflammation. Supplements are reported to be beneficial, however, a disadvantage of consuming nutrients from a synthetic source can rob the athlete of a healthy mixture of nutrients and minerals. Overall, consumption of proper nutrients can aid in the recovery process following an injury and sleep is an important factor that should also be considered while the body heals.

The brain continuously monitors speech output to detect potential errors between its sensory prediction and its sensory production (Daliri et al., 2020). When the brain encounters an error, it generates a corrective motor response, usually in the opposite direction, to reduce the effect of the error. Previous studies have shown that the type of auditory error received may impact a participant’s corrective response. In this study, we examined whether participants respond differently to categorical or non-categorical errors. We applied two types of perturbation in real-time by shifting the first formant (F1) and second formant (F2) at three different magnitudes. The vowel /ɛ/ was shifted toward the vowel /æ/ in the categorical perturbation condition. In the non-categorical perturbation condition, the vowel /ɛ/ was shifted to a sound outside of the vowel quadrilateral (increasing both F1 and F2). Our results showed that participants responded to the categorical perturbation while they did not respond to the non-categorical perturbation. Additionally, we found that in the categorical perturbation condition, as the magnitude of the perturbation increased, the magnitude of the response increased. Overall, our results suggest that the brain may respond differently to categorical and non-categorical errors, and the brain is highly attuned to errors in speech.

The following paper explores the various effects of stress on the endocrine system. Many understand that being stressed can jeopardize maintaining adequate health, but what specifically happens when humans are stressed? Why does stress affect human health? This paper delves into background information, previous research, and the depths to which stress negatively affects the body. The effects stress has on the endocrine system, specifically on the hypothalamic-pituitary-thyroid axis (HPT) and hypothalamic-pituitary-adrenal axis (HPA), is discussed, and additionally, at home de-stressing methods are researched. The study included a set of participants at Arizona State University. The method took place over the course of 2 weeks: one normal week, and the other with the implementation of a de-stressing method. The normal week involved the participants living their daily lives with the addition of a stress-measuring survey, while the second week involved implementing a de-stressing method and stress-measuring survey. The purpose of this study was to discover if there was a correlation between performing these relaxation activities and decreasing stress levels in ASU students. The results found that students reported they felt more relaxed and calm after the activities. Overall, this thesis provides information and first hand research on the effects of stress and stress-reducing activities and discusses the importance of maintaining lower stress levels throughout everyday life.

Contraceptive methods are vital in maintaining women’s health and preventing unintended pregnancy. When a woman uses a method that reflects her personal preferences and lifestyle, the chances of low adoption and misuse decreases. The research aim of this project is to develop a web-based decision aid tailored to college women that assists in the selection of contraceptive methods. For this reason, My Contraceptive Choice (MCC) is built using the gaps identified in existing resources provided by Planned Parenthood and Bedsider, along with feedback from a university student focus group. The tool is a short quiz that is followed by two pages of information and resources for a variety of different contraceptive methods commonly used by college women. The evaluation phase of this project includes simulated test cases, a Google Forms survey, and a second focus group to assess the tool for accuracy and usability. From the survey, 130 of the 150 (80.7%) responses believe that the recommendations provided can help them select a birth control method. Furthermore, 136 of the 150 (90.0%) responses believe that the layout of the tool made it easy to navigate. The second focus group feedback suggests that the MCC tool is perceived to be accurate, usable, and useful to the college population. Participants believe that the MCC tool performs better overall compared to the Planned Parenthood quiz in creating a customized recommendation and Bedsider in overall usability. The test cases reveal that there are further improvements that could be made to create a more accurate recommendation to the user. In conclusion, the new MCC tool accomplishes the aim of creating a beneficial resource to college women in assisting with the birth control selection process.

Anxiety is one of the most common mental illnesses in the United States. In this project, I chose to explore how food is one of the most accessible and inexpensive ways of treating anxiety. This creative project examines the major key components of gut health including the balance of neurotransmitters and bacteria in the gut, restoring hydrochloric acid through celery juice, removing heavy metal toxins through food, eating fermented foods, and limiting refined carbohydrates, and high-sugar consumption. Additionally, this creative project explores my own personal journey through the implementation of foods that influence anxiety revealed in a systemic review over the course of a 6-week period.

The United States healthcare system does not perform as well as other countries including Germany and England, despite spending the most money on healthcare. It is well-established that there have been attempts at reform in the U.S. healthcare system multiple times in the past. This research paper describes the health care systems in the U.S., Germany, and England to analyze the strengths to create practical healthcare reform ideas for the U.S. This was done by describing each of the country's health care systems in detail, including the history of each country's health care system, the quality of care, the access to care, and the funding of the health care system. Based on this analysis of these health care systems, recommendations for health care reform are provided for the U.S. with revisions to the Affordable Care Act.

Brave Bears was a Barrett creative project that operated under local non-profit organizations, Amanda Hope Rainbow Angels and Arizona Women’s Recovery Center. Amanda Hope Rainbow Angels provides support and education for children fighting cancer and their families. Arizona Women’s Recovery Center provides rehabilitation programs for women fighting substance abuse and housing for the women and their children. The Brave Bears Project was focused on helping children in these situations cope with the trauma they are experiencing. The children received a teddy bear, which is a transitional object. In addition, a clay pendant with the word, “brave” pressed into it was tied around the bear’s neck with a ribbon. A poem of explanation and encouragement was also included.<br/><br/>The teddy bear provided comfort to children experiencing emotionally distressing situations as they receive treatment for their illness or as their mom undergoes rehabilitation. This can be in the form of holding the teddy bear when they feel frightened, anxious, lonely or depressed. The “brave” pendant and poem seek to encourage them and acknowledge their trauma and ability to persevere.

College is the first time many students will experience living away from home and with learning how to manage college course loads, students also need to figure out how to feed themselves for the next four years. The focus of this thesis will be to assess the current food environment available at Arizona State University. The Perceived Food Environment (PFE) Model was used to evaluate the accessibility, affordability, acceptability, and adequacy of the residential dining halls, restaurants, and marketplaces.<br/><br/>The Tempe and Downtown Phoenix campuses’ food environments were used in this paper to determine what they offer and how healthy the food options are for students. Both campuses combined offer 32 possible choices for students to dine. The Tempe campus has 4 dining halls, 15 fast-casual restaurants, and 5 Provisions on Demand (P.O.D) Markets. The Downton campus has 1 dining hall, 6 fast-casual restaurants, 1 P.O.D Market, and 1 marketplace. <br/><br/>Both campuses have good accessibility to all their dining options, even though Downtown lacks many options compared to Tempe. Dining halls also have good accessibility for students who have meal plans. Affordability did vary among locations, it seemed as though many of the healthier restaurants were either too expensive or, in the case of Engrained on the Tempe campus, open for a short amount of time. The fast-casual restaurants seemed to be more affordable and appear in larger amounts than the healthier options. Marketplaces on campus lack fresh food to choose from, so they also promote the habit of poor eating choices. For acceptability, all dining options are popular on campus and accept payments in cash, card, or Maroon & Gold Dollars (M&G). <br/><br/>Overall, the food environment at ASU seems to favor more unhealthy food options. Students do not have much of a choice when needing to find food on campus because there is a lack of fresh ingredients or a kitchen to use. There are also barriers that risk promoting poor food choice that needs to be addressed to solve this problem.