Theses and Dissertations
This collection includes both ASU Theses and Dissertations, submitted by graduate students, and the Barrett, Honors College theses submitted by undergraduate students.
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- Creators: Gipson-Reichardt, Cassandra
- Creators: Murwin, Paige Elizabeth
Description
Nicotine addiction remains a prevalent public health issue, and the FDA has released a statement outlining the systematic reduction of nicotine to non-zero levels in the coming years. Current research has not yet established the effects of abrupt nicotine dose reduction on vulnerability to relapse, nor has abrupt nicotine dose reduction been evaluated in terms of behavioral economic characteristics of demand and elasticity been evaluated for reduced doses of nicotine. Using a rat model, we first evaluated the comparability of between- and within-session protocols for establishing characteristics of demand and elasticity for nicotine to shorten experimental timelines for this study and future studies. We then tested environmental enrichment and sex as factors of elasticity of demand for nicotine. Using a rat model of relapse to cues, we also examined the effects of nicotine dose-reduction on vulnerability to relapse. We found differences in maximum consumption and demand between the between- and within-session protocols, as well as sex differences in elasticity of demand on the within-session protocol where male demand was more elastic than female demand. Additionally, we found that enrichment significantly increased elasticity of demand for nicotine for both males and females. Finally, preliminary analyses revealed that nicotine dose reduction yields more inelastic demand and higher maximum consumption, and these outcomes predict increased time to extinction of the association between nicotine and contingent cues, and increased rates of relapse. These studies highlight the usefulness and validity of within-session protocols, and also illustrate the necessity for rigorous testing of forced dose reduction on nicotine vulnerability.
ContributorsCabrera-Brown, Gabriella Paula (Author) / Gipson-Reichardt, Cassandra (Thesis director) / Olive, M. Foster (Committee member) / Davis, Mary (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
Emotions have been defined as coordinated and functional changes in subjective experience, motivation, physiological activation, instrumental behavior, expressive behavior, and cognition that are evoked by important threats or opportunities in the environment. The proposed study looks at cognitive changes associated with the experience of several positive emotions, with a specific focus on awe. Prior research shows that positive emotions tend to increase people's use of cognitive heuristics (i.e. mental shortcuts used to simplify information we intake from the environment) and changes how they apply rules of thumb from stored knowledge to make decisions. Stereotypes, or assumptions about the characteristics held by individual members of a group, are one such heuristic. Awe, in contrast to other positive emotions, has been found to reduce people's tendency to rely on heuristics, rather than increasing its use. Thus, awe should tend to reduce stereotyping specifically. Participants made judgments on three characteristics and two types of theoretically valuable true/false statements. However, for both our measures, awe had no significant effect on stereotyping. Participants in the enthusiasm condition were significantly more likely than those in the awe condition to correctly identify stereotype-inconsistent statements present in the biography, which is the opposite of the predicted direction. Patterns for all four emotion conditions trended similarly to our predictions for stereotype-consistent statements correctly marked as being absent in the biography. There were no significant differences in ratings of three traits. Implications for enthusiasm and awe are discussed in the context of stereotypes of social objects and schemas of nonsocial objects.
ContributorsMurwin, Paige Elizabeth (Co-author) / O'Neil, Makenzie (Co-author) / Shiota, Michelle (Thesis director) / Davis, Mary (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12