Theses and Dissertations
This collection includes both ASU Theses and Dissertations, submitted by graduate students, and the Barrett, Honors College theses submitted by undergraduate students.
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- Creators: Su, Jinni
Description
Pediatric chronic pain is pervasive and associated with myriad adverse consequences, yet due consideration has not been given to the mental health disturbances that often present alongside chronic pain and the etiological mechanisms that potentially underlie both. The current study examined the etiology underlying chronic pain and internalizing symptomology in middle childhood, considering both independent and co-occurring symptom presentations. Phenotypic parent-offspring associations across chronic pain and internalizing symptomology were also examined. Lastly, nuclear twin family models were tested to determine the extent to which genetic and environmental factors underlie parent-offspring transmission. The sample comprised 795 children (399 families; Mage= 9.7 years; SD = 0.92) and their parents drawn from the Arizona Twin Project. Results indicated that chronic pain was highly heritable (78%), whereas internalizing symptomology was modestly heritable (32%) and further subject to moderate shared environmental influence (50%). Moreover, 9% of the variance in chronic pain was explained by additive genetic factors shared with internalizing symptomology. Maternal chronic pain and internalizing symptomology were positively associated with both child chronic pain and internalizing symptomology. The association between maternal chronic pain and child chronic pain was more pronounced for girls than boys, whereas the association between maternal internalizing symptomology and child internalizing symptomology was more pronounced for boys than girls. Paternal chronic pain was not significantly associated with child chronic pain but was unexpectedly associated with lower child internalizing symptomology. The negative association between paternal chronic pain and child internalizing symptomology was more pronounced for boys than girls. Paternal internalizing symptomology was not significantly associated with child chronic pain but was positively associated with child internalizing symptomology. Lastly, the best fitting reduced nuclear twin family models for both chronic pain and internalizing symptomology retained additive genetic, sibling-specific shared environmental, and nonshared environmental parameters, where parent-offspring transmission was solely explained by shared genetics and sibling-specific shared environmental factors further accounted for co-twin resemblance. Results provide novel insight into common liabilities underlying chronic pain and internalizing symptomology in middle childhood, parent-offspring associations across chronic pain and internalizing symptomology, and the etiological mechanisms that explain symptom aggregation across generations.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Davis, Mary (Committee member) / Su, Jinni (Committee member) / Arizona State University (Publisher)
Created2021
Description
Sleep and weight health during childhood can be the essential building blocks that influence later physical and psychological health. Researchers note how neighborhood effects on health may be mediated or moderated by parenting or family-related factors. This dissertation expanded on the efforts through an examination of contextual predictors of children’s health using the Arizona Twin Project dataset (N = 933; 51.7% female; 56.5% White; 25.6% Latino). The family stress model (FSM), contextual relevance model (CRM), and the integrated model were used to test the relations between neighborhood and family factors on children sleep and weight health. Parent perceptions of neighborhood danger and childhood opportunities index were tested using multilevel- mediation, moderation, and moderated mediation models to address some of the limitations in previous reviews. The FSM was partially supported: parental stress and strain mediated the association between perceived neighborhood danger with sleep efficiency. However, the FSM was not fully supported as parental stress and disrupted parenting did not serially mediate the associations between neighborhood conditions and sleep efficiency. Moderation analyses revealed that negative parenting exacerbates associations between perceived neighborhood danger and sleep duration, demonstrating amplified disadvantages processes of the CRM. Negative parenting also moderated the associations between perceived neighborhood danger and sleep efficiency; the relationship was beyond what was noted in the CRM. Greater neighborhood opportunity was more strongly related to greater body fat percentage in families with higher positive parenting, as compared to families with lower positive parenting. Familism significantly moderated the association between neighborhood contexts and parental stress and strain within a subsample (Latino descent only). Last, the exploratory multilevel moderated mediation models suggested that most associations did not vary by the subgroups explored (i.e., positive parenting, familism cultural value). These results join a growing initiative to explore the science of ecological context, culture, and family interplay.
ContributorsPark, HyeJung (Author) / Doane, Leah D. (Thesis advisor) / White, Rebecca M.B. (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Su, Jinni (Committee member) / Arizona State University (Publisher)
Created2022
Description
This study investigated whether the patterns of direct association, and of gene-environment interaction (GxE), between family variables (i.e., parenting, family conflict, and attitudinal familism) and youth externalizing behaviors differed across racial/ethnic groups. The sample was composed of 772 twin pairs from the Adolescent Brain Development Study (ABCD) and analyses were run on three racial/ethnic groups (White [n=1023], Black/African American [n=220], Hispanic [n=152]; Mage=10.14 years). Youth reports of parental warmth, parental monitoring, family conflict, parent-reported attitudinal familism, and parent reports of youth externalizing behaviors were collected at baseline when children were 10 years old. Regression analyses tested the direct association between the family variables and youth externalizing behaviors, and moderated heritability models tested for GxE. Family conflict was associated with more externalizing behaviors for White youth, and parental warmth was associated with fewer externalizing behaviors for Hispanic youth. Parental attitudinal familism composite and familism support were associated with fewer externalizing behaviors for Black youth but more externalizing behaviors for Hispanic youth. We found no effects for parental monitoring, familism obligations, and familism referent on youth externalizing behaviors. Additive genetic and non-shared environmental influences explained the variance in youth externalizing behaviors across all groups. For White youth, parental warmth, parental monitoring, and familism support moderated additive genetic (A), shared-environmental (C), and non-shared environmental (E) influences on externalizing behaviors, and familism obligations moderated C and E influences. Results from exploratory moderated heritability analyses conducted for the Black/African American and Hispanic samples are discussed. Altogether, these findings highlight the multiple avenues through which the family context can impact the development of youth externalizing behaviors, and reinforce the need to examine how these relations differ across racial/ethnic groups.
ContributorsTrevino, Angel Daniel (Author) / Su, Jinni (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Causadias, Jose (Committee member) / Arizona State University (Publisher)
Created2023
Description
This dissertation combines three first-author manuscripts that focused broadly on the study of adolescent sleep within a family context (Sasser et al., 2021; Sasser & Oshri, 2023; Sasser et al., 2023). First, Chapter 1 introduces the theoretical background and empirical research that grounded the research questions and hypotheses explored across the studies. The first study (Chapter 2) examined the influence of family connection on actigraphy-measured sleep among Latinx late adolescents and explored family dynamics and cultural values as potential moderators. The second study (Chapter 3) investigated daily and average concordance between parent and youth actigraphy-measured sleep and how this varied as a function of family context (e.g., parenting, family functioning). The third study (Chapter 4) examined concordance in actigraphy sleep among parent-youth and sibling dyads and explored how relations differed across zygosity type and sleeping arrangements. The dissertation concludes with an immersive discussion (Chapter 5) that summarizes the key differences, similarities, and takeaways across studies and highlights future directions and implications for developmental science, public policy, and clinical interventions. Collectively, this dissertation contributes to the understanding of youth and adolescent sleep within a family context by identifying proximal (e.g., daily interactions with parents/siblings) and broader family-level factors (e.g., dynamics, culture) that may help promote more healthful sleep among both adolescents and their family members.
ContributorsSasser, Jeri (Author) / Doane, Leah D (Thesis advisor) / Su, Jinni (Committee member) / Grimm, Kevin J (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Arizona State University (Publisher)
Created2023