Theses and Dissertations
This collection includes both ASU Theses and Dissertations, submitted by graduate students, and the Barrett, Honors College theses submitted by undergraduate students.
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- Creators: Turaga, Pavan
Description
Semantic image segmentation has been a key topic in applications involving image processing and computer vision. Owing to the success and continuous research in the field of deep learning, there have been plenty of deep learning-based segmentation architectures that have been designed for various tasks. In this thesis, deep-learning architectures for a specific application in material science; namely the segmentation process for the non-destructive study of the microstructure of Aluminum Alloy AA 7075 have been developed. This process requires the use of various imaging tools and methodologies to obtain the ground-truth information. The image dataset obtained using Transmission X-ray microscopy (TXM) consists of raw 2D image specimens captured from the projections at every beam scan. The segmented 2D ground-truth images are obtained by applying reconstruction and filtering algorithms before using a scientific visualization tool for segmentation. These images represent the corrosive behavior caused by the precipitates and inclusions particles on the Aluminum AA 7075 alloy. The study of the tools that work best for X-ray microscopy-based imaging is still in its early stages.
In this thesis, the underlying concepts behind Convolutional Neural Networks (CNNs) and state-of-the-art Semantic Segmentation architectures have been discussed in detail. The data generation and pre-processing process applied to the AA 7075 Data have also been described, along with the experimentation methodologies performed on the baseline and four other state-of-the-art Segmentation architectures that predict the segmented boundaries from the raw 2D images. A performance analysis based on various factors to decide the best techniques and tools to apply Semantic image segmentation for X-ray microscopy-based imaging was also conducted.
In this thesis, the underlying concepts behind Convolutional Neural Networks (CNNs) and state-of-the-art Semantic Segmentation architectures have been discussed in detail. The data generation and pre-processing process applied to the AA 7075 Data have also been described, along with the experimentation methodologies performed on the baseline and four other state-of-the-art Segmentation architectures that predict the segmented boundaries from the raw 2D images. A performance analysis based on various factors to decide the best techniques and tools to apply Semantic image segmentation for X-ray microscopy-based imaging was also conducted.
ContributorsBarboza, Daniel (Author) / Turaga, Pavan (Thesis advisor) / Chawla, Nikhilesh (Committee member) / Jayasuriya, Suren (Committee member) / Arizona State University (Publisher)
Created2020
Description
Antibiotic resistance is a very important issue that threatens mankind. As bacteria
are becoming resistant to multiple antibiotics, many common antibiotics will soon
become ineective. The ineciency of current methods for diagnostics is an important
cause of antibiotic resistance, since due to their relative slowness, treatment plans
are often based on physician's experience rather than on test results, having a high
chance of being inaccurate or not optimal. This leads to a need of faster, pointof-
care (POC) methods, which can provide results in a few hours. Motivated by
recent advances on computer vision methods, three projects have been developed
for bacteria identication and antibiotic susceptibility tests (AST), with the goal of
speeding up the diagnostics process. The rst two projects focus on obtaining features
from optical microscopy such as bacteria shape and motion patterns to distinguish
active and inactive cells. The results show their potential as novel methods for AST,
being able to obtain results within a window of 30 min to 3 hours, a much faster
time frame than the gold standard approach based on cell culture, which takes at
least half a day to be completed. The last project focus on the identication task,
combining large volume light scattering microscopy (LVM) and deep learning to
distinguish bacteria from urine particles. The developed setup is suitable for pointof-
care applications, as a large volume can be viewed at a time, avoiding the need
for cell culturing or enrichment. This is a signicant gain compared to cell culturing
methods. The accuracy performance of the deep learning system is higher than chance
and outperforms a traditional machine learning system by up to 20%.
are becoming resistant to multiple antibiotics, many common antibiotics will soon
become ineective. The ineciency of current methods for diagnostics is an important
cause of antibiotic resistance, since due to their relative slowness, treatment plans
are often based on physician's experience rather than on test results, having a high
chance of being inaccurate or not optimal. This leads to a need of faster, pointof-
care (POC) methods, which can provide results in a few hours. Motivated by
recent advances on computer vision methods, three projects have been developed
for bacteria identication and antibiotic susceptibility tests (AST), with the goal of
speeding up the diagnostics process. The rst two projects focus on obtaining features
from optical microscopy such as bacteria shape and motion patterns to distinguish
active and inactive cells. The results show their potential as novel methods for AST,
being able to obtain results within a window of 30 min to 3 hours, a much faster
time frame than the gold standard approach based on cell culture, which takes at
least half a day to be completed. The last project focus on the identication task,
combining large volume light scattering microscopy (LVM) and deep learning to
distinguish bacteria from urine particles. The developed setup is suitable for pointof-
care applications, as a large volume can be viewed at a time, avoiding the need
for cell culturing or enrichment. This is a signicant gain compared to cell culturing
methods. The accuracy performance of the deep learning system is higher than chance
and outperforms a traditional machine learning system by up to 20%.
ContributorsIriya, Rafael (Author) / Turaga, Pavan (Thesis advisor) / Wang, Shaopeng (Committee member) / Grys, Thomas (Committee member) / Zhang, Yanchao (Committee member) / Arizona State University (Publisher)
Created2020