Theses and Dissertations
This collection includes both ASU Theses and Dissertations, submitted by graduate students, and the Barrett, Honors College theses submitted by undergraduate students.
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Description
Missing data are common in psychology research and can lead to bias and reduced power if not properly handled. Multiple imputation is a state-of-the-art missing data method recommended by methodologists. Multiple imputation methods can generally be divided into two broad categories: joint model (JM) imputation and fully conditional specification (FCS) imputation. JM draws missing values simultaneously for all incomplete variables using a multivariate distribution (e.g., multivariate normal). FCS, on the other hand, imputes variables one at a time, drawing missing values from a series of univariate distributions. In the single-level context, these two approaches have been shown to be equivalent with multivariate normal data. However, less is known about the similarities and differences of these two approaches with multilevel data, and the methodological literature provides no insight into the situations under which the approaches would produce identical results. This document examined five multilevel multiple imputation approaches (three JM methods and two FCS methods) that have been proposed in the literature. An analytic section shows that only two of the methods (one JM method and one FCS method) used imputation models equivalent to a two-level joint population model that contained random intercepts and different associations across levels. The other three methods employed imputation models that differed from the population model primarily in their ability to preserve distinct level-1 and level-2 covariances. I verified the analytic work with computer simulations, and the simulation results also showed that imputation models that failed to preserve level-specific covariances produced biased estimates. The studies also highlighted conditions that exacerbated the amount of bias produced (e.g., bias was greater for conditions with small cluster sizes). The analytic work and simulations lead to a number of practical recommendations for researchers.
ContributorsMistler, Stephen (Author) / Enders, Craig K. (Thesis advisor) / Aiken, Leona (Committee member) / Levy, Roy (Committee member) / West, Stephen G. (Committee member) / Arizona State University (Publisher)
Created2015
Description
Investigation of measurement invariance (MI) commonly assumes correct specification of dimensionality across multiple groups. Although research shows that violation of the dimensionality assumption can cause bias in model parameter estimation for single-group analyses, little research on this issue has been conducted for multiple-group analyses. This study explored the effects of mismatch in dimensionality between data and analysis models with multiple-group analyses at the population and sample levels. Datasets were generated using a bifactor model with different factor structures and were analyzed with bifactor and single-factor models to assess misspecification effects on assessments of MI and latent mean differences. As baseline models, the bifactor models fit data well and had minimal bias in latent mean estimation. However, the low convergence rates of fitting bifactor models to data with complex structures and small sample sizes caused concern. On the other hand, effects of fitting the misspecified single-factor models on the assessments of MI and latent means differed by the bifactor structures underlying data. For data following one general factor and one group factor affecting a small set of indicators, the effects of ignoring the group factor in analysis models on the tests of MI and latent mean differences were mild. In contrast, for data following one general factor and several group factors, oversimplifications of analysis models can lead to inaccurate conclusions regarding MI assessment and latent mean estimation.
ContributorsXu, Yuning (Author) / Green, Samuel (Thesis advisor) / Levy, Roy (Committee member) / Thompson, Marilyn (Committee member) / Arizona State University (Publisher)
Created2018
Description
A simulation study was conducted to explore the robustness of general factor mean difference estimation in bifactor ordered-categorical data. In the No Differential Item Functioning (DIF) conditions, the data generation conditions varied were sample size, the number of categories per item, effect size of the general factor mean difference, and the size of specific factor loadings; in data analysis, misspecification conditions were introduced in which the generated bifactor data were fit using a unidimensional model, and/or ordered-categorical data were treated as continuous data. In the DIF conditions, the data generation conditions varied were sample size, the number of categories per item, effect size of latent mean difference for the general factor, the type of item parameters that had DIF, and the magnitude of DIF; the data analysis conditions varied in whether or not setting equality constraints on the noninvariant item parameters.
Results showed that falsely fitting bifactor data using unidimensional models or failing to account for DIF in item parameters resulted in estimation bias in the general factor mean difference, while treating ordinal data as continuous had little influence on the estimation bias as long as there was no severe model misspecification. The extent of estimation bias produced by misspecification of bifactor datasets with unidimensional models was mainly determined by the degree of unidimensionality (i.e., size of specific factor loadings) and the general factor mean difference size. When the DIF was present, the estimation accuracy of the general factor mean difference was completely robust to ignoring noninvariance in specific factor loadings while it was very sensitive to failing to account for DIF in threshold parameters. With respect to ignoring the DIF in general factor loadings, the estimation bias of the general factor mean difference was substantial when the DIF was -0.15, and it can be negligible for smaller sizes of DIF. Despite the impact of model misspecification on estimation accuracy, the power to detect the general factor mean difference was mainly influenced by the sample size and effect size. Serious Type I error rate inflation only occurred when the DIF was present in threshold parameters.
Results showed that falsely fitting bifactor data using unidimensional models or failing to account for DIF in item parameters resulted in estimation bias in the general factor mean difference, while treating ordinal data as continuous had little influence on the estimation bias as long as there was no severe model misspecification. The extent of estimation bias produced by misspecification of bifactor datasets with unidimensional models was mainly determined by the degree of unidimensionality (i.e., size of specific factor loadings) and the general factor mean difference size. When the DIF was present, the estimation accuracy of the general factor mean difference was completely robust to ignoring noninvariance in specific factor loadings while it was very sensitive to failing to account for DIF in threshold parameters. With respect to ignoring the DIF in general factor loadings, the estimation bias of the general factor mean difference was substantial when the DIF was -0.15, and it can be negligible for smaller sizes of DIF. Despite the impact of model misspecification on estimation accuracy, the power to detect the general factor mean difference was mainly influenced by the sample size and effect size. Serious Type I error rate inflation only occurred when the DIF was present in threshold parameters.
ContributorsLiu, Yixing (Author) / Thompson, Marilyn (Thesis advisor) / Levy, Roy (Committee member) / O’Rourke, Holly (Committee member) / Arizona State University (Publisher)
Created2019
Description
A simulation study was conducted to explore the influence of partial loading invariance and partial intercept invariance on the latent mean comparison of the second-order factor within a higher-order confirmatory factor analysis (CFA) model. Noninvariant loadings or intercepts were generated to be at one of the two levels or both levels for a second-order CFA model. The numbers and directions of differences in noninvariant loadings or intercepts were also manipulated, along with total sample size and effect size of the second-order factor mean difference. Data were analyzed using correct and incorrect specifications of noninvariant loadings and intercepts. Results summarized across the 5,000 replications in each condition included Type I error rates and powers for the chi-square difference test and the Wald test of the second-order factor mean difference, estimation bias and efficiency for this latent mean difference, and means of the standardized root mean square residual (SRMR) and the root mean square error of approximation (RMSEA).
When the model was correctly specified, no obvious estimation bias was observed; when the model was misspecified by constraining noninvariant loadings or intercepts to be equal, the latent mean difference was overestimated if the direction of the difference in loadings or intercepts of was consistent with the direction of the latent mean difference, and vice versa. Increasing the number of noninvariant loadings or intercepts resulted in larger estimation bias if these noninvariant loadings or intercepts were constrained to be equal. Power to detect the latent mean difference was influenced by estimation bias and the estimated variance of the difference in the second-order factor mean, in addition to sample size and effect size. Constraining more parameters to be equal between groups—even when unequal in the population—led to a decrease in the variance of the estimated latent mean difference, which increased power somewhat. Finally, RMSEA was very sensitive for detecting misspecification due to improper equality constraints in all conditions in the current scenario, including the nonzero latent mean difference, but SRMR did not increase as expected when noninvariant parameters were constrained.
When the model was correctly specified, no obvious estimation bias was observed; when the model was misspecified by constraining noninvariant loadings or intercepts to be equal, the latent mean difference was overestimated if the direction of the difference in loadings or intercepts of was consistent with the direction of the latent mean difference, and vice versa. Increasing the number of noninvariant loadings or intercepts resulted in larger estimation bias if these noninvariant loadings or intercepts were constrained to be equal. Power to detect the latent mean difference was influenced by estimation bias and the estimated variance of the difference in the second-order factor mean, in addition to sample size and effect size. Constraining more parameters to be equal between groups—even when unequal in the population—led to a decrease in the variance of the estimated latent mean difference, which increased power somewhat. Finally, RMSEA was very sensitive for detecting misspecification due to improper equality constraints in all conditions in the current scenario, including the nonzero latent mean difference, but SRMR did not increase as expected when noninvariant parameters were constrained.
ContributorsLiu, Yixing (Author) / Thompson, Marilyn (Thesis advisor) / Green, Samuel (Committee member) / Levy, Roy (Committee member) / Arizona State University (Publisher)
Created2016
Description
This dissertation explores applications of machine learning methods in service of the design of screening tests, which are ubiquitous in applications from social work, to criminology, to healthcare. In the first part, a novel Bayesian decision theory framework is presented for designing tree-based adaptive tests. On an application to youth delinquency in Honduras, the method produces a 15-item instrument that is almost as accurate as a full-length 150+ item test. The framework includes specific considerations for the context in which the test will be administered, and provides uncertainty quantification around the trade-offs of shortening lengthy tests. In the second part, classification complexity is explored via theoretical and empirical results from statistical learning theory, information theory, and empirical data complexity measures. A simulation study that explicitly controls two key aspects of classification complexity is performed to relate the theoretical and empirical approaches. Throughout, a unified language and notation that formalizes classification complexity is developed; this same notation is used in subsequent chapters to discuss classification complexity in the context of a speech-based screening test. In the final part, the relative merits of task and feature engineering when designing a speech-based cognitive screening test are explored. Through an extensive classification analysis on a clinical speech dataset from patients with normal cognition and Alzheimer’s disease, the speech elicitation task is shown to have a large impact on test accuracy; carefully performed task and feature engineering are required for best results. A new framework for objectively quantifying speech elicitation tasks is introduced, and two methods are proposed for automatically extracting insights into the aspects of the speech elicitation task that are driving classification performance. The dissertation closes with recommendations for how to evaluate the obtained insights and use them to guide future design of speech-based screening tests.
ContributorsKrantsevich, Chelsea (Author) / Hahn, P. Richard (Thesis advisor) / Berisha, Visar (Committee member) / Lopes, Hedibert (Committee member) / Renaut, Rosemary (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2023
Description
Linear-regression estimators have become widely accepted as a reliable statistical tool in predicting outcomes. Because linear regression is a long-established procedure, the properties of linear-regression estimators are well understood and can be trained very quickly. Many estimators exist for modeling linear relationships, each having ideal conditions for optimal performance. The differences stem from the introduction of a bias into the parameter estimation through the use of various regularization strategies. One of the more popular ones is ridge regression which uses ℓ2-penalization of the parameter vector. In this work, the proposed graph regularized linear estimator is pitted against the popular ridge regression when the parameter vector is known to be dense. When additional knowledge that parameters are smooth with respect to a graph is available, it can be used to improve the parameter estimates. To achieve this goal an additional smoothing penalty is introduced into the traditional loss function of ridge regression. The mean squared error(m.s.e) is used as a performance metric and the analysis is presented for fixed design matrices having a unit covariance matrix. The specific problem setup enables us to study the theoretical conditions where the graph regularized estimator out-performs the ridge estimator. The eigenvectors of the laplacian matrix indicating the graph of connections between the various dimensions of the parameter vector form an integral part of the analysis. Experiments have been conducted on simulated data to compare the performance of the two estimators for laplacian matrices of several types of graphs – complete, star, line and 4-regular. The experimental results indicate that the theory can possibly be extended to more general settings taking smoothness, a concept defined in this work, into consideration.
ContributorsSajja, Akarshan (Author) / Dasarathy, Gautam (Thesis advisor) / Berisha, Visar (Committee member) / Yang, Yingzhen (Committee member) / Arizona State University (Publisher)
Created2022
Description
Currently, there is a clear gap in the missing data literature for three-level models.
To date, the literature has only focused on the theoretical and algorithmic work
required to implement three-level imputation using the joint model (JM) method of
imputation, leaving relatively no work done on fully conditional specication (FCS)
method. Moreover, the literature lacks any methodological evaluation of three-level
imputation. Thus, this thesis serves two purposes: (1) to develop an algorithm in
order to implement FCS in the context of a three-level model and (2) to evaluate
both imputation methods. The simulation investigated a random intercept model
under both 20% and 40% missing data rates. The ndings of this thesis suggest
that the estimates for both JM and FCS were largely unbiased, gave good coverage,
and produced similar results. The sole exception for both methods was the slope for
the level-3 variable, which was modestly biased. The bias exhibited by the methods
could be due to the small number of clusters used. This nding suggests that future
research ought to investigate and establish clear recommendations for the number of
clusters required by these imputation methods. To conclude, this thesis serves as a
preliminary start in tackling a much larger issue and gap in the current missing data
literature.
To date, the literature has only focused on the theoretical and algorithmic work
required to implement three-level imputation using the joint model (JM) method of
imputation, leaving relatively no work done on fully conditional specication (FCS)
method. Moreover, the literature lacks any methodological evaluation of three-level
imputation. Thus, this thesis serves two purposes: (1) to develop an algorithm in
order to implement FCS in the context of a three-level model and (2) to evaluate
both imputation methods. The simulation investigated a random intercept model
under both 20% and 40% missing data rates. The ndings of this thesis suggest
that the estimates for both JM and FCS were largely unbiased, gave good coverage,
and produced similar results. The sole exception for both methods was the slope for
the level-3 variable, which was modestly biased. The bias exhibited by the methods
could be due to the small number of clusters used. This nding suggests that future
research ought to investigate and establish clear recommendations for the number of
clusters required by these imputation methods. To conclude, this thesis serves as a
preliminary start in tackling a much larger issue and gap in the current missing data
literature.
ContributorsKeller, Brian Tinnell (Author) / Enders, Craig K. (Thesis advisor) / Grimm, Kevin J. (Committee member) / Levy, Roy (Committee member) / Arizona State University (Publisher)
Created2015
Description
Eigenvalues of the Gram matrix formed from received data frequently appear in sufficient detection statistics for multi-channel detection with Generalized Likelihood Ratio (GLRT) and Bayesian tests. In a frequently presented model for passive radar, in which the null hypothesis is that the channels are independent and contain only complex white Gaussian noise and the alternative hypothesis is that the channels contain a common rank-one signal in the mean, the GLRT statistic is the largest eigenvalue $\lambda_1$ of the Gram matrix formed from data. This Gram matrix has a Wishart distribution. Although exact expressions for the distribution of $\lambda_1$ are known under both hypotheses, numerically calculating values of these distribution functions presents difficulties in cases where the dimension of the data vectors is large. This dissertation presents tractable methods for computing the distribution of $\lambda_1$ under both the null and alternative hypotheses through a technique of expanding known expressions for the distribution of $\lambda_1$ as inner products of orthogonal polynomials. These newly presented expressions for the distribution allow for computation of detection thresholds and receiver operating characteristic curves to arbitrary precision in floating point arithmetic. This represents a significant advancement over the state of the art in a problem that could previously only be addressed by Monte Carlo methods.
ContributorsJones, Scott, Ph.D (Author) / Cochran, Douglas (Thesis advisor) / Berisha, Visar (Committee member) / Bliss, Daniel (Committee member) / Kosut, Oliver (Committee member) / Richmond, Christ (Committee member) / Arizona State University (Publisher)
Created2019
Description
This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely capturing the complexity of GRN interactions through the introduction of time-varying kinetic order parameters, while allowing for variability in multiple model parameters. This model is used as the drift function in the development of several stochastic GRN mod- els based on Langevin dynamics. Six models are introduced which capture intrinsic and extrinsic noise in GRNs, thereby providing a full characterization of a stochastic regulatory system. A Bayesian hierarchical approach is developed for learning the Langevin model which best describes the noise dynamics at each time step. The trajectory of the state, which are the gene expression values, as well as the indicator corresponding to the correct noise model are estimated via sequential Monte Carlo (SMC) with a high degree of accuracy. To address the problem of time-varying regulatory interactions, a Bayesian hierarchical model is introduced for learning variation in switching GRN architectures with unknown measurement noise covariance. The trajectory of the state and the indicator corresponding to the network configuration at each time point are estimated using SMC. This work is extended to a fully Bayesian hierarchical model to account for uncertainty in the process noise covariance associated with each network architecture. An SMC algorithm with local Gibbs sampling is developed to estimate the trajectory of the state and the indicator correspond- ing to the network configuration at each time point with a high degree of accuracy. The results demonstrate the efficacy of Bayesian methods for learning information in switching nonlinear GRNs.
ContributorsVélez-Cruz, Nayely (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Moraffah, Bahman (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Berisha, Visar (Committee member) / Arizona State University (Publisher)
Created2023