Theses and dissertations

This collection includes both ASU Theses and Dissertations, submitted by graduate students, and the Barrett, Honors College theses submitted by undergraduate students. 

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The impact of childhood family adversity on nighttime change in blood pressure

Description
Adverse childhood family environments have been found to have long-term effects on a child's well-being. Although no prior studies have examined the direct effects of childhood family adversities on nighttime blood pressure (BP) dip, parental death and divorce in childhood, have been associated with a variety of related psychological problems…

Adverse childhood family environments have been found to have long-term effects on a child's well-being. Although no prior studies have examined the direct effects of childhood family adversities on nighttime blood pressure (BP) dip, parental death and divorce in childhood, have been associated with a variety of related psychological problems in adulthood. The current study examined the direct effects of parental death and divorce in childhood and quality of early family relationships on adult nighttime BP dip as well as the mediating role of three psychosocial factors (depression, hostility and social stress). One hundred and forty-three young adults were asked to complete self-reported measures of the three psychosocial factors and quality of family relationships. Study participants wore an ambulatory blood pressure (ABP) monitor over a 24-hr period in order to assess nocturnal BP dip. Although neither childhood family adversity nor quality of childhood family relationships directly predicted nighttime BP dipping, quality of early family relationships predicted all three psychosocial factors, and hostility was found to mediate the relationship between quality of childhood family relationships and nighttime systolic BP dip. Early family experiences play an important role in influencing nighttime cardiovascular functioning by influencing an individual's psychological functioning in young adulthood. Because nighttime non-dipping has been associated with increased risk for cardiovascular disease and other serious health conditions, the results of the present study have important clinical implications and provide specific psychosocial pathways that may be targeted in future programs designed to prevent and treat cardiovascular disease.
ContributorsTanaka, Rika (Author) / Luecken, Linda J. (Thesis advisor) / Wolchik, Sharlene (Committee member) / Davis, Mary (Committee member) / Arizona State University (Publisher)
Created2012
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The Comparison of Frontostriatal Tracts Between Adolescents with ADHD and a Typically Developing Adolescent Control Group

Description
The frontostriatal reward circuit serves an underlying role in reward processing, cognitive planning, and motor control in the context of achieving a goal. Furthermore, research suggests a relationship between the reward circuits and behavior expressed in Attention Deficit Hyperactivity Disorder (ADHD); however, the specific structural differences of the reward circuits…

The frontostriatal reward circuit serves an underlying role in reward processing, cognitive planning, and motor control in the context of achieving a goal. Furthermore, research suggests a relationship between the reward circuits and behavior expressed in Attention Deficit Hyperactivity Disorder (ADHD); however, the specific structural differences of the reward circuits in those with ADHD remain ambiguous. Diffusion tensor imaging (DTI) techniques were used to analyze diffusion weighted magnetic resonance imaging (DWI) data in order to examine the structural connectivity of frontostriatal reward pathways in ADHD adolescents compared to typically developing (TD) adolescents. It was hypothesized that measures of impulsivity would be predicted by white matter tract integrity measures in frontostriatal tracts related to affective processing (ventromedial prefrontal cortex to ventral striatum, vmPFC) in adolescents with ADHD, and that there would be reduced tract integrity in tracts related to executive control (dorsolateral prefrontal and anterior cingulate cortex—dlPFC and ACC, respectively). Frontostriatal tracts as well as the hippocampus and amygdala were examined in relation to age and impulsivity using both correlation and regression models. Results indicated that impulsivity declined with age in the TD group while no significant trend was identified for the ADHD group. The hypotheses were not supported and results for both predictions on the affective and executive circuits showed opposite trends from what was expected.
ContributorsHarrison, Sydney Rae (Author) / McClure, Samuel (Thesis director) / Brewer, Gene (Committee member) / Davis, Mary (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12