ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
Displaying 1 - 10 of 112
Description
With the advent of technologies such as web services, service oriented architecture and cloud computing, modern organizations have to deal with policies such as Firewall policies to secure the networks, XACML (eXtensible Access Control Markup Language) policies for controlling the access to critical information as well as resources. Management of these policies is an extremely important task in order to avoid unintended security leakages via illegal accesses, while maintaining proper access to services for legitimate users. Managing and maintaining access control policies manually over long period of time is an error prone task due to their inherent complex nature. Existing tools and mechanisms for policy management use different approaches for different types of policies. This research thesis represents a generic framework to provide an unified approach for policy analysis and management of different types of policies. Generic approach captures the common semantics and structure of different access control policies with the notion of policy ontology. Policy ontology representation is then utilized for effectively analyzing and managing the policies. This thesis also discusses a proof-of-concept implementation of the proposed generic framework and demonstrates how efficiently this unified approach can be used for analysis and management of different types of access control policies.
ContributorsKulkarni, Ketan (Author) / Ahn, Gail-Joon (Thesis advisor) / Yau, Stephen S. (Committee member) / Huang, Dijiang (Committee member) / Arizona State University (Publisher)
Created2011
Description
This research describes software based remote attestation schemes for obtaining the integrity of an executing user application and the Operating System (OS) text section of an untrusted client platform. A trusted external entity issues a challenge to the client platform. The challenge is executable code which the client must execute, and the code generates results which are sent to the external entity. These results provide the external entity an assurance as to whether the client application and the OS are in pristine condition. This work also presents a technique where it can be verified that the application which was attested, did not get replaced by a different application after completion of the attestation. The implementation of these three techniques was achieved entirely in software and is backward compatible with legacy machines on the Intel x86 architecture. This research also presents two approaches to incorporating software based "root of trust" using Virtual Machine Monitors (VMMs). The first approach determines the integrity of an executing Guest OS from the Host OS using Linux Kernel-based Virtual Machine (KVM) and qemu emulation software. The second approach implements a small VMM called MIvmm that can be utilized as a trusted codebase to build security applications such as those implemented in this research. MIvmm was conceptualized and implemented without using any existing codebase; its minimal size allows it to be trustworthy. Both the VMM approaches leverage processor support for virtualization in the Intel x86 architecture.
ContributorsSrinivasan, Raghunathan (Author) / Dasgupta, Partha (Thesis advisor) / Colbourn, Charles (Committee member) / Shrivastava, Aviral (Committee member) / Huang, Dijiang (Committee member) / Dewan, Prashant (Committee member) / Arizona State University (Publisher)
Created2011
Description
Natural photosynthesis features a complex biophysical/chemical process that requires sunlight to produce energy rich products. It is one of the most important processes responsible for the appearance and sustainability of life on earth. The first part of the thesis focuses on understanding the mechanisms involved in regulation of light harvesting, which is necessary to balance the absorption and utilization of light energy and in that way reduce the effect caused by photooxidative damage. In photosynthesis, carotenoids are responsible not only for collection of light, but also play a major role in protecting the photosynthetic system. To investigate the role of carotenoids in the quenching of the excited state of cyclic tetrapyrroles, two sets of dyads were studied. Both sets of dyads contain zinc phthalocyanine (Pc) covalently attached to carotenoids of varying conjugation lengths. In the first set of dyads, carotenoids were attached to the phthalocyanine via amide linkage. This set of dyads serves as a good model for understanding the molecular "gear-shift" mechanism, where the addition of one double bond can turn the carotenoid from a nonquencher to a very strong quencher of the excited state of a tetrapyrrole. In the second set of dyads, carotenoids were attached to phthalocyanine via a phenyl amino group. Two independent studies were performed on these dyads: femtosecond transient absorption and steady state fluorescence induced by two-photon excitation. In the transient absorption study it was observed that there is an instantaneous population of the carotenoid S1 state after Pc excitation, while two-photon excitation of the optically forbidden carotenoid S1 state shows 1Pc population. Both observations provide a strong indication of the existence of a shared excitonic state between carotenoid and Pc. Similar results were observed in LHC II complexes in plants, supporting the role of such interactions in photosynthetic down regulation. In the second chapter we describe the synthesis of porphyrin dyes functionalized with carboxylate and phosphonate anchoring groups to be used in the construction of photoelectrochemical cells containing a porphyrin-IrO2·nH2O complex immobilized on a TiO2 electrode. The research presented here is a step in the development of high potential porphyrin-metal oxide complexes to be used in the photooxidation of water. The last chapter focuses on developing synthetic strategies for the construction of an artificial antenna system consisting of porphyrin-silver nanoparticle conjugates, linked by DNA of varied length to study the distance dependence of the interaction between nanoparticles and the porphyrin chromophore. Preliminary studies indicate that at the distance of about 7-10 nm between porphyrin and silver nanoparticle is where the porphyrin absorption leading to fluorescence shows maximum enhancement. These new hybrid constructs will be helpful for designing efficient light harvesting systems.
ContributorsPillai, Smitha (Author) / Moore, Ana (Thesis advisor) / Moore, Thomas (Committee member) / Gould, Ian (Committee member) / Arizona State University (Publisher)
Created2011
Description
In order to catch the smartest criminals in the world, digital forensics examiners need a means of collaborating and sharing information with each other and outside experts that is not prohibitively difficult. However, standard operating procedures and the rules of evidence generally disallow the use of the collaboration software and techniques that are currently available because they do not fully adhere to the dictated procedures for the handling, analysis, and disclosure of items relating to cases. The aim of this work is to conceive and design a framework that provides a completely new architecture that 1) can perform fundamental functions that are common and necessary to forensic analyses, and 2) is structured such that it is possible to include collaboration-facilitating components without changing the way users interact with the system sans collaboration. This framework is called the Collaborative Forensic Framework (CUFF). CUFF is constructed from four main components: Cuff Link, Storage, Web Interface, and Analysis Block. With the Cuff Link acting as a mediator between components, CUFF is flexible in both the method of deployment and the technologies used in implementation. The details of a realization of CUFF are given, which uses a combination of Java, the Google Web Toolkit, Django with Apache for a RESTful web service, and an Ubuntu Enterprise Cloud using Eucalyptus. The functionality of CUFF's components is demonstrated by the integration of an acquisition script designed for Android OS-based mobile devices that use the YAFFS2 file system. While this work has obvious application to examination labs which work under the mandate of judicial or investigative bodies, security officers at any organization would benefit from the improved ability to cooperate in electronic discovery efforts and internal investigations.
ContributorsMabey, Michael Kent (Author) / Ahn, Gail-Joon (Thesis advisor) / Yau, Stephen S. (Committee member) / Huang, Dijiang (Committee member) / Arizona State University (Publisher)
Created2011
Description
A potential new class of cancer chemotherapeutic agents has been synthesized by varying the 2 position of a benzimidazole based extended amidine. Compounds 6-amino-2-chloromethyl-4-imino-1-(2-methansulfonoxyethyl)-5-methyl-1H-benzimidazole-7-one (1A) and 6-amino-2-hydroxypropyl-4-imino-1-(2-methansulfonoxyethyl)-5-methyl-1H-benzimidazole-7-one (1B) were assayed at the National Cancer Institute's (NCI) Developmental Therapeutic Program (DTP) and found to be cytotoxic at sub-micromolar concentrations, and have shown between a 100 and a 1000-fold increase in specificity towards lung, colon, CNS, and melanoma cell lines. These ATP mimics have been found to correlate with sequestosome 1 (SQSTM1), a protein implicated in drug resistance and cell survival in various cancer cell lines. Using the DTP COMPARE algorithm, compounds 1A and 1B were shown to correlate to each other at 77%, but failed to correlate with other benzimidazole based extended amidines previously synthesized in this laboratory suggesting they operate through a different biological mechanism.
ContributorsDarzi, Evan (Author) / Skibo, Edward (Thesis advisor) / Gould, Ian (Committee member) / Francisco, Wilson (Committee member) / Arizona State University (Publisher)
Created2011
Description
Natural photosynthesis dedicates specific proteins to achieve the modular division of the essential roles of solar energy harvesting, charge separation and carrier transport within natural photosynthesis. The modern understanding of the fundamental photochemistry by which natural photosynthesis operates is well advanced and solution state mimics of the key photochemical processes have been reported previously. All of the early events in natural photosynthesis responsible for the conversion of solar energy to electric potential energy occur within proteins and phospholipid membranes that act as scaffolds for arranging the active chromophores. Accordingly, for creating artificial photovoltaic (PV) systems, scaffolds are required to imbue structure to the systems. An approach to incorporating modular design into solid-state organic mimics of the natural system is presented together with how conductive scaffolds can be utilized in organic PV systems. To support the chromophore arrays present within this design and to extract separated charges from within the structure, linear pyrazine-containing molecular ribbons were chosen as candidates for forming conductive linear scaffolds that could be functionalized orthogonally to the linear axis. A series of donor-wire-acceptor (D-W-A) compounds employing porphyrins as the donors and a C60 fullerene adduct as the acceptors have been synthesized for studying the ability of the pyrazine-containing hetero-aromatic wires to mediate photoinduced electron transfer between the porphyrin donor and fullerene acceptor. Appropriate substitutions were made and the necessary model compounds useful for dissecting the complex photochemistry that the series is expected to display were also synthesized. A dye was synthesized using a pyrazine-containing heteroaromatic spacer that features two porphyrin chromophores. The dye dramatically outperforms the control dye featuring the same porphyrin and a simple benzoic acid linker. A novel, highly soluble 6+kDa extended phthalocyanine was also synthesized and exhibits absorption out to 900nm. The extensive functionalization of the extended phthalocyanine core with dodecyl groups enabled purification and characterization of an otherwise insoluble entity. Finally, in the interest of incorporating modular design into plastic solar cells, a series of porphyrin-containing monomers have been synthesized that are intended to form dyadic and triadic molecular-heterojunction polymers with dedicated hole and electron transport pathways during electrochemical polymerization.
ContributorsWatson, Brian Lyndon (Author) / Gust, Devens (Thesis advisor) / Gould, Ian (Committee member) / Moore, Ana L (Committee member) / Arizona State University (Publisher)
Created2013
Description
The bleomycins are a family of glycopeptide-derived antibiotics isolated from various Streptomyces species and have been the subject of much attention from the scientific community as a consequence of their antitumor activity. Bleomycin clinically and is an integral part of a number of combination chemotherapy regimens. It has previously been shown that bleomycin has the ability to selectively target tumor cells over their non-malignant counterparts. Pyrimidoblamic acid, the N-terminal metal ion binding domain of bleomycin is known to be the moiety that is responsible for O2 activation and the subsequent chemistry leading to DNA strand scission and overall antitumor activity. Chapter 1 describes bleomycin and related DNA targeting antitumor agents as well as the specific structural domains of bleomycin. Various structural analogues of pyrimidoblamic acid were synthesized and subsequently incorporated into their corresponding full deglycoBLM A6 derivatives by utilizing a solid support. Their activity was measured using a pSP64 DNA plasmid relaxation assay and is summarized in Chapter 2. The specifics of bleomycin—DNA interaction and kinetics were studied via surface plasmon resonance and are presented in Chapter 3. By utilizing carefully selected 64-nucleotide DNA hairpins with variable 16-mer regions whose sequences showed strong binding in past selection studies, a kinetic profile was obtained for several BLMs for the first time since bleomycin was discovered in 1966. The disaccharide moiety of bleomycin has been previously shown to be a specific tumor cell targeting element comprised of L-gulose-D-mannose, especially between MCF-7 (breast cancer cells) and MCF-10A ("normal" breast cells). This phenomenon was further investigated via fluorescence microscopy using multiple cancerous cell lines with matched "normal" counterparts and is fully described in Chapter 4.
ContributorsBozeman, Trevor C (Author) / Hecht, Sidney M. (Thesis advisor) / Chaput, John (Committee member) / Gould, Ian (Committee member) / Arizona State University (Publisher)
Created2013
Description
Nuclear magnetic resonance (NMR) is an important phenomenon involving nuclear magnetic moments in magnetic field, which can provide much information about a wide range of materials, including their chemical composition, chemical environments and nuclear spin interactions. The NMR spectrometer has been extensively developed and used in many areas of research. In this thesis, studies in two different areas using NMR are presented. First, a new kind of nanoparticle, Gd(DTPA) intercalated layered double hydroxide (LDH), has been successfully synthesized in the laboratory of Prof. Dey in SEMTE at ASU. In Chapter II, the NMR relaxation studies of two types of LDH (Mg, Al-LDH and Zn, Al-LDH) are presented and the results show that when they are intercalated with Gd(DTPA) they have a higher relaxivity than current commercial magnetic resonance imaging (MRI) contrast agents, such as DTPA in water solution. So this material may be useful as an MRI contrast agent. Several conditions were examined, such as nanoparticle size, pH and intercalation percentage, to determine the optimal relaxivity of this nanoparticle. Further NMR studies and simulations were conducted to provide an explanation for the high relaxivity. Second, fly ash is a kind of cementitious material, which has been of great interest because, when activated by an alkaline solution, it exhibits the capability for replacing ordinary Portland cement as a concrete binder. However, the reaction of activated fly ash is not fully understood. In chapter III, pore structure and NMR studies of activated fly ash using different activators, including NaOH and KOH (4M and 8M) and Na/K silicate, are presented. The pore structure, degree of order and proportion of different components in the reaction product were obtained, which reveal much about the reaction and makeup of the final product.
ContributorsPeng, Zihui (Author) / Marzke, Robert F (Thesis advisor) / Dey, Sandwip Kumar (Committee member) / Neithalath, Narayanan (Committee member) / Chamberlin, Ralph Vary (Committee member) / Mccartney, Martha Rogers (Committee member) / Arizona State University (Publisher)
Created2013
Description
This study focused on investigating the ability of a polymeric-enhanced high-tenacity fabric composite called CarbonFlex to mitigate damages from multi-natural hazards, which are earthquakes and tornadoes, in wood-framed structures. Typically, wood-framed shear wall is a seismic protection system used in low-rise wood structures. It is well-known that the main energy dissipation of the system is its fasteners (nails) which are not enough to dissipate energy leading to decreasing of structure's integrity. Moreover, wood shear walls could not sustain their stiffness after experiencing moderate wall drift which made them susceptible to strong aftershocks. Therefore, CarbonFlex shear wall system was proposed to be used in the wood-framed structures. Seven full-size CarbonFlex shear walls and a CarbonFlex wrapped structures were tested. The results were compared to those of conventional wood-framed shear walls and a wood structure. The comparisons indicated that CarbonFlex specimens could sustain their strength and fully recover their initial stiffness although they experienced four percent story drift while the stiffness of the conventional structure dramatically degraded. This indicated that CarbonFlex shear wall systems provided a better seismic protection to wood-framed structures. To evaluate capability of CarbonFlex to resist impact damages from wind-borne debris in tornadoes, several debris impact tests of CarbonFlex and a carbon fiber reinforced storm shelter's wall panels were conducted. The results showed that three CarbonFlex wall panels passed the test at the highest debris impact speed and the other two passed the test at the second highest speed while the carbon fiber panel failed both impact speeds.
ContributorsDhiradhamvit, Kittinan (Author) / Attard, Thomas L (Thesis advisor) / Fafitis, Apostolos (Thesis advisor) / Neithalath, Narayanan (Committee member) / Thomas, Benjamin (Committee member) / Arizona State University (Publisher)
Created2013
Description
The energy consumption of data centers is increasing steadily along with the associ- ated power-density. Approximately half of such energy consumption is attributed to the cooling energy, as a result of which reducing cooling energy along with reducing servers energy consumption in data centers is becoming imperative so as to achieve greening of the data centers. This thesis deals with cooling energy management in data centers running data-processing frameworks. In particular, we propose ther- mal aware scheduling for MapReduce framework and its Hadoop implementation to reduce cooling energy in data centers. Data-processing frameworks run many low- priority batch processing jobs, such as background log analysis, that do not have strict completion time requirements; they can be delayed by a bounded amount of time. Cooling energy savings are possible by being able to temporally spread the workload, and assign it to the computing equipments which reduce the heat recirculation in data center room and therefore the load on the cooling systems. We implement our scheme in Hadoop and performs some experiments using both CPU-intensive and I/O-intensive workload benchmarks in order to evaluate the efficiency of our scheme. The evaluation results highlight that our thermal aware scheduling reduces hot-spots and makes uniform temperature distribution within the data center possible. Sum- marizing the contribution, we incorporated thermal awareness in Hadoop MapReduce framework by enhancing the native scheduler to make it thermally aware, compare the Thermal Aware Scheduler(TAS) with the Hadoop scheduler (FCFS) by running PageRank and TeraSort benchmarks in the BlueTool data center of Impact lab and show that there is reduction in peak temperature and decrease in cooling power using TAS over FCFS scheduler.
ContributorsKole, Sayan (Author) / Gupta, Sandeep (Thesis advisor) / Huang, Dijiang (Committee member) / Varsamopoulos, Georgios (Committee member) / Arizona State University (Publisher)
Created2013