Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
In 2014 alone, 40% of all drug abuse-related emergency department visits involved cocaine, and despite the detrimental effects there is still no FDA approved treatment for cocaine use disorders (CUDs; Dawn, 2014). Studies show that serotonin 1B receptor (5HT1BR) agonists modulate cocaine abuse-related behaviors in opposite directions depending on the phase of the addiction cycle in male rats. In particular, the selective 5HT1BR agonist, CP94,253, facilitates cocaine intake during maintenance of daily cocaine self-administration. Paradoxically, after 21 days of abstinence, CP94,253 attenuates cocaine intake in male rats on a low effort fixed ratio 5 (FR5) and a high effort progressive ratio (PR) schedule of reinforcement. PR measures motivation as it requires an exponentially increasing number of lever responses to obtain the next reinforcer after a successful reinforcer. In contrast to male rats, we recently found CP94,253 attenuates cocaine intake before and after abstinence on an FR5 schedule of reinforcement in female rats, suggesting the attenuating effects of CP94,253 on cocaine intake is not dependent on a period of abstinence in females. However, the effect of CP94,253 on motivation for cocaine has not yet been examined in female rats. Therefore, we addressed this gap in the present study. Female Sprague-Dawley rats were trained to self-administer 0.375 mg/kg, IV cocaine or to obtain sucrose pellets (45 mg) on a PR schedule of reinforcement and were then pretreated with vehicle or CP94,253 (3.2, 5.6 and 10 mg/kg, SC) prior to their self-administration session. A separate cohort was pretreated with CP94,253 to examine the effects of CP94,253 on cocaine-seeking behavior (i.e., operant responses when cocaine is no longer available) and spontaneous locomotion after 21 or 60 days of abstinence. The preliminary findings show that CP94,253 has minimal impacts on decreasing cocaine intake on a PR schedule in female rats but decreases cue reactivity up to 60 days after abstinence in female rats. These findings suggest that 5-HT1BR agonists may be useful treatments for cocaine craving.
Chloe Bosmeny and Audree López, senior marketing students at W. P. Carey have created a proposal for W. P. Carey School of Business and Herberger Institute for Design and the Arts to join together to create an interdisciplinary resource for students interested in pursuing a career in fashion. There are three recommendations in the thesis: the implementation of a Fashion Merchandising certificate encompassing both W. P. Carey and Herberger curriculum, ASU joining the Fashion Institute of Technology’s 3+1 program for dual degrees in New York City, and lastly, improving professional development and career recruitment for ASU students interested in fashion.
But why fashion at Arizona State University? Throughout college, Bosmeny and López struggled to gain the background, skills and experience needed to understand the fashion industry. They, like many of their peers, felt that without the credentials of a university-sponsored fashion program, they weren't marketable to employers. These challenges drove Bosmeny and López to advocate for more fashion resources at ASU.
Based on support from student surveys, in-depth interviews with industry professionals, feedback from ASU Alumni and input from ASU’s largest fashion organization, The Business of Fashion Club- there is a strong desire for increased fashion programming at ASU. There are currently 266 student theses surrounding the keyword “fashion” from Barrett, the Honors College, but there has not been a direct push from students to implement a program at ASU. This thesis aims to illustrate the important ways such programming will greatly benefit ASU and its stakeholders.
In our thesis we will investigate current ASU opportunities related to fashion, gather information from fashion business professionals, gauge student interest in pursuing careers in fashion, and look to peer and aspirational schools in an effort to better understand fashion career resources nationwide. Our hope is to build a stronger curriculum and more successful resources for students to give them the skillsets needed for a successful career in fashion.