Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

Displaying 1 - 10 of 30
133348-Thumbnail Image.png
Description
The inception of the human-powered water pump began during my trip to Maasailand in Kenya over the Summer of 2017. Being one of the few Broadening the Reach of Engineering through Community Engagement (BRECE) Scholars at Arizona State University, I was given the opportunity to join Prescott College (PC) on

The inception of the human-powered water pump began during my trip to Maasailand in Kenya over the Summer of 2017. Being one of the few Broadening the Reach of Engineering through Community Engagement (BRECE) Scholars at Arizona State University, I was given the opportunity to join Prescott College (PC) on their annual trip to the Maasai Education, Research, and Conservation (MERC) Institute in rural Kenya. The ASU BRECE scholars that choose to travel were asked to collaborate with the local Maasai community to help develop functional and sustainable engineering solutions to problems identified alongside community members using rudimentary technology and tools that were available in this resource-constrained setting. This initiative evolved into multiple projects from the installation of GravityLights (a local invention that powers LEDs with falling sandbags), the construction/installation of smokeless stoves, and development of a much-needed solution to move water from the rainwater collection tanks around camp to other locations. This last project listed was prototyped once in camp, and this report details subsequent iterations of this human-powered pump.
ContributorsMiller, Miles Edward (Author) / Henderson, Mark (Thesis director) / Abbas, James (Committee member) / Engineering Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
135383-Thumbnail Image.png
Description
Billions of people around the world deal with the struggles of poverty every day. Consequently, a number of others have committed themselves to help alleviate poverty. Many various methods are used, and a current consensus on the best method to alleviate poverty is lacking. Generally the methods used or researched

Billions of people around the world deal with the struggles of poverty every day. Consequently, a number of others have committed themselves to help alleviate poverty. Many various methods are used, and a current consensus on the best method to alleviate poverty is lacking. Generally the methods used or researched exist somewhere on the spectrum between top-down and bottom-up approaches to fighting poverty. This paper analyzes a specific method proposed by C.K. Prahalad known as the Bottom of the Pyramid solution. The premise of the method is that large multinational corporations should utilize the large conglomerate of money that exists amongst poor people \u2014 created due to the sheer number of poor people \u2014 for business ventures. Concurrently, the poor people can benefit from the company's entrance. This method has received acclaim theoretically, but still needs empirical evidence to prove its practicality. This paper compares this approach with other approaches, considers international development data trends, and analyzes case studies of actual attempts that provide insight into the approach's potential for success. The market of poor people at the bottom of the pyramid is extremely segmented which makes it very difficult for large companies to financially prosper. It is even harder to establish mutual benefit between the large corporation and the poor. It has been found that although aspects of the bottom of the pyramid method hold merit, higher potential for alleviating poverty exists when small companies venture into this space rather than large multinational corporations. Small companies can conform to a single community and niche economy to prosper \u2014 a flexibility that large companies lack. Moving forward, analyzing the actual attempts provides the best and only empirical insights; hence, it will be important to consider more approaches into developing economies as they materialize.
ContributorsSanchez, Derek Javier (Author) / Henderson, Mark (Thesis director) / Shunk, Dan (Committee member) / Industrial, Systems (Contributor) / Economics Program in CLAS (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
135392-Thumbnail Image.png
Description
In recent history, the world has been inspired to respond to the challenges faced by communities with ‘help’. This help has been administered with moderate success through community engagement strategies traditionally centered on social services provided through non-profit agencies. Social entrepreneurship has emerged in response to the lack of progress

In recent history, the world has been inspired to respond to the challenges faced by communities with ‘help’. This help has been administered with moderate success through community engagement strategies traditionally centered on social services provided through non-profit agencies. Social entrepreneurship has emerged in response to the lack of progress made in solving local and global issues with new innovations that have the potential to change the status quo and eliminate the problems for future generations. In social entrepreneurship, concerned individuals saw an opportunity to truly change the world. Higher education leaders have embraced social entrepreneurship, positioning university students as a driving force behind ideating creative and innovative solutions that can be implemented in communities to overcome a vast array of challenges from poverty to environmental sustainability. Despite the efforts of university staff and faculty, many student changemakers struggle to successfully implement their ideas and measure their impact. Factors such as how well the student understands the issue and community in addition to the extent to which the student is experienced in ideation, creative-problem solving, and implementation of projects contribute to the success or failure of a student social effort. Inspired by their experiences serving as director of Changemaker Central, the authors sought to understand the process of preparing students to be agents of change in the community. Having observed the variance in success among aspiring changemakers at Arizona State University (ASU), the researchers studied how to best support students in preparation for a high-impact career. The research analyzed students’ experiences in two of ASU’s social change programs, Changemaker Challenge (CC) and University Service-Learning (USL) and found a need for more cohesion between two programs and their represented methodologies in addition to a need for in-depth analysis on the student journey.
ContributorsMicevic, Vid (Co-author) / Fitzgerald, Kaitlyn (Co-author) / Henderson, Mark (Thesis director) / Smith, Jacqueline (Committee member) / Civil, Environmental and Sustainable Engineering Programs (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
136669-Thumbnail Image.png
Description
"Seventy five percent of the world's poor live in rural areas of developing countries, where most people's livelihoods rely directly on agriculture." (USAid, 2014) Reduced levels of crop production and the accompanying problems of malnourishment exist all over the world. In rural Peru, for example, 11 percent of the population

"Seventy five percent of the world's poor live in rural areas of developing countries, where most people's livelihoods rely directly on agriculture." (USAid, 2014) Reduced levels of crop production and the accompanying problems of malnourishment exist all over the world. In rural Peru, for example, 11 percent of the population is malnourished. (Global Healthfacts.org, 2012) Since the success in agriculture relies importantly on the fertility of the soil, it is imperative that any efforts at reversing this trend be primarily directed at improving the existing soils. This, in turn, will increase crop yields, and if done properly, will also conserve natural resources and maximize profits for farmers. In order to improve the lives of those at the bottom of the pyramid through agriculture, certain tools and knowledge must be provided in order to empower such persons to help themselves. An ancient method of soil improvement, known as Terra Preta do Indio (Indian dark earth), was discovered by Anthropologists in the 1800's. These dark, carbon-rich, soils are notable for their high fertility, high amounts of plant available nutrients, and their high moisture retention rates. The key to their long-lasting fertility and durability is the presence of high levels of biochar, a highly stable organic carbon \u2014 produced when organic matter (crop residues, food waste, manure, etc.) is burned at low temperatures in the absence of oxygen. Research has shown that when charcoal (biochar) and fertilizers are combined, it can yield as much as 880 percent more than when fertilizers are used by themselves. (Steiner, University of Bayreuth, 2004)
ContributorsStefanik, Kathleen Ann (Author) / Henderson, Mark (Thesis director) / Johnson, Nathan (Committee member) / Barrett, The Honors College (Contributor) / Human Systems Engineering (Contributor)
Created2014-12
Description
I. Executive Summary Projectors are used in more and more live and corporate events and theatrical productions. In these environments, they are subject to a myriad of conditions. These can include extreme temperatures, atmospheric effects and contaminates, shipping and rough handling, and power issues. The goal is to find ways

I. Executive Summary Projectors are used in more and more live and corporate events and theatrical productions. In these environments, they are subject to a myriad of conditions. These can include extreme temperatures, atmospheric effects and contaminates, shipping and rough handling, and power issues. The goal is to find ways to extend the reliable and economical lifespan of these machines increasing companies ROI and decreasing environmental damage from more frequent production, repair and disposal. The first area studied was the effect removing the covers has on the projector performance. This is important knowledge for both the research protocols followed in this research and in normal use during maintenance and repair. Testing demonstrated that the removal of covers on small consumer projectors has a profound impact on internal temperatures and can even cause overheating due to the covers being used as air ducting. The main focus of this project was finding effective pre-filters for use around haze, fog and other airborne contaminates. This was successful with two material being demonstrated to be cost effective, filter far superior to factory filters alone, and produce acceptable impacts on projector cooling in several models and types of projector. These filters cost typically less than $1 per filter and reduce the ingress of contaminates by 60-80%. Additionally the effects of improper shutdown versus the manufacturers specified shutdown process were tested. It was determined that the projectors where power was unplugged or turned off had components exceed both operating temperatures and temperatures during the normal shutdown. This shows that following the correct shutdown process keeps components cooler leading to a longer component life and therefore longer projector life and decreased repairs.
ContributorsBooth, Kelsey (Author) / Henderson, Mark (Thesis director) / Pinholster, Jacob (Committee member) / Gaddy, Davin (Committee member) / Barrett, The Honors College (Contributor)
Created2014-05
136115-Thumbnail Image.png
Description
Background: Both puberty and diets composed of high levels of saturated fats have been shown to result in central adiposity, fasting hyperinsulinemia, insulin resistance and impaired glucose tolerance. While a significantly insulinogenic phenotypic change occurs in these two incidences, glucose homeostasis does not appear to be affected. Methods: Male, Sprague-dawley

Background: Both puberty and diets composed of high levels of saturated fats have been shown to result in central adiposity, fasting hyperinsulinemia, insulin resistance and impaired glucose tolerance. While a significantly insulinogenic phenotypic change occurs in these two incidences, glucose homeostasis does not appear to be affected. Methods: Male, Sprague-dawley rats were fed diets consisting of CHOW or low fat (LF), High Fat Diet and High Fat Diet (HFD) with supplementary Canola Oil (Monounsaturated fat). These rats were given these diets at 4-5 weeks old and given intraperitoneal and oral glucose tolerance tests(IPGTT; OGTT) at 4 and 8 weeks to further understand glucose and insulin behavior under different treatments. (IPGTT: LF-n=14, HFD-n=16, HFD+CAN-n=12; OGTT: LF-n=8, HFD-n=8, HFD+CAN-n=6). Results: When comparing LF fed rats at 8 weeks with 4 week glucose challenge test, area under the curve (AUC) of glucose was 1.2 that of 4 weeks. At 8 weeks, HFD fed rats AUCg was much greater than LF fed rats under both IPGTT and OGTT. When supplemented with Canola oil, HFD fed rats AUC returned to LF data range. Despite the alleviating glucose homeostasis affects of Canola oil the AUC of insulin curve, which was elevated by HFD, remained high. Conclusion: HFD in maturing rats elevates fasting insulin levels, increases insulin resistance and lowers glucose homeostasis. When given a monounsaturated fatty acid (MUFA) supplement fasting hyperinsulinemia, and late hyperinsulinemia still occur though glucose homeostasis is regained. For OGTT HFD also induced late hyper c-peptide levels and compared to LF and HFD+CAN, a higher c-peptide level over time.
ContributorsRay, Tyler John (Author) / Caplan, Michael (Thesis director) / Herman, Richard (Committee member) / Towner, Kali (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / W. P. Carey School of Business (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2015-05
136011-Thumbnail Image.png
Description
Sickle cell disease is a genetic disorder that can cause substantial helath problems. It is the result of a mutation in the DNA coding for hemoglobin. As a result of changes in two important amino acids, a person suffering from sickle cell disease will have erythrocytes that do not maintain

Sickle cell disease is a genetic disorder that can cause substantial helath problems. It is the result of a mutation in the DNA coding for hemoglobin. As a result of changes in two important amino acids, a person suffering from sickle cell disease will have erythrocytes that do not maintain the typical biconcave shape and instead for a crescent shape. Individuals with sickle cell disease may have many health problems tied to their irregular hemoglobin. The unusual shape of the erythrocytes leads to a much shorter cell life, which means that even though bone marrow remains active long past childhood to try to keep up with the loss of erythrocytes, the body is still unable to accommodate the rapid death of erythrocytes. The malformed erythrocytes can also cause vascular occlusion, blocking blood vessels and slowing blood flow. While sickle cell disease has the potential to spread worldwide, it is particularly common in Africa. This may be because people with the sickle cell trait have a high resistance to malaria, making them more likely to survive that ubiquitous disease and pass on their traits to their offspring. However, the mortality rate in young children with sickle cell disease is very high, in part because the spleen, already stressed by filtering out dead erythrocytes, has difficulties filtering out bacteria. One of the keys to stopping the spread of the disease is neonatal screening, but this requires specialized equipment that is fairly uncommon in rural areas, as can be seen in Kenya. Therefore, it would be highly beneficial to develop a more cost-effective and widely available method for testing for sickle cell disease.
ContributorsWold, John (Author) / Caplan, Michael (Thesis director) / LaBelle, Jeffrey (Committee member) / Snyder, Jan (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
136163-Thumbnail Image.png
Description
This Honors thesis is analyzing the Jaipur Prosthetic Foot; we are using a foot from Bhagwan Mahaveer Viklang Sahayata Samiti (BMVSS) to test the durability of the foot and where the critical fatigue points are located. Our testing design will be based off of computer simulation to point out the

This Honors thesis is analyzing the Jaipur Prosthetic Foot; we are using a foot from Bhagwan Mahaveer Viklang Sahayata Samiti (BMVSS) to test the durability of the foot and where the critical fatigue points are located. Our testing design will be based off of computer simulation to point out the critical points that the test machinery should accentuate. The machine will be set to sample and save data at interval times throughout the accentuated walking cycle in order to record the point where the foot begins to show wear.
ContributorsChaisson, Nathaniel (Co-author) / Jacobs, Ian (Co-author) / Radda, Nicholas (Co-author) / Henderson, Mark (Thesis director) / Sodemann, Angela (Committee member) / Carberry, Adam (Committee member) / Barrett, The Honors College (Contributor)
Created2015-05
133807-Thumbnail Image.png
Description
Microvillus Inclusion disease is a fatal disease found in the Navajo population caused by a single nucleotide polymorphism. It is characterized by intractable diarrhea and is often fatal early in life.1 The current method of diagnosis is sending duodenal biopsies for histopathological examination and confirmatory testing through genomic sequencing. The

Microvillus Inclusion disease is a fatal disease found in the Navajo population caused by a single nucleotide polymorphism. It is characterized by intractable diarrhea and is often fatal early in life.1 The current method of diagnosis is sending duodenal biopsies for histopathological examination and confirmatory testing through genomic sequencing. The purpose of this experiment was to create a more simple and cost-effective diagnostic method for detecting Microvillus Inclusion disease. Three methods were explored (RFLP2, ARMS3,4, and Tentacle Probes5,6) and two methods were tested to determine their ability and their efficiency in detecting the SNP that causes the disease.2 Tests using the RFLP2 method and synthetic DNA resulted in 9% false-positive rate and 11% false-negative rate in a blind trial for detecting both target (mutation present) and non-target (mutation absent) DNA when gel analyzing software was used to compare Rf values after gel electrophoresis. Using the ARMS method3, a nine-sample randomized test was run that ended up with 22% false-positive rate and 19% false-negative rate from a blind trial when using a gel analyzing software to determine presence of the SNP by band intensity. Disclaimer: No DNA from human patients was used in this study. Only synthetic DNA used.
ContributorsHelmbrecht, Hawley Elizabeth (Author) / Caplan, Michael (Thesis director) / Carpentieri, David (Committee member) / Dubois, Courtney (Committee member) / Chemical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Imaging analysis of local drug delivery is important because in both studies involving chemotherapy targeted toward glioblastoma and antimicrobial addressing infection, the drug concentration and distribution are unknown. There are a variety of studies focused on the local delivery of drug to a targeted location, but we are presenting a

Imaging analysis of local drug delivery is important because in both studies involving chemotherapy targeted toward glioblastoma and antimicrobial addressing infection, the drug concentration and distribution are unknown. There are a variety of studies focused on the local delivery of drug to a targeted location, but we are presenting a way of quantifying the concentration of the drug and the distribution of the drug during a period of time. This study aims to do that by utilizing Materialise Mimics to analyze the MRI images of local drug delivery in glioblastoma in canines and antimicrobial gel in rabbit femurs. The focus of the technique is to register the anatomy in T1-weighted spin echo images to the drug delivery in T2 flow attenuated inversion recovery (FLAIR) images in order to see where the drug went and did not go relative to the anatomical part. Both studies focus on addressing effective volumes of drug to a designated anatomical area, in which the delivery can be difficult as it involves bypassing the blood brain barrier in the first study and achieving effective volumes while preventing toxicity to the kidneys in the second study. The goal of this project lies in determining the drug volumes and location for the specified duration and anatomical part.
ContributorsJehng, Hope (Author) / Caplan, Michael (Thesis director) / Sirianni, Rachael (Committee member) / Chemical Engineering Program (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05