Barrett, The Honors College Thesis/Creative Project Collection

Mentions of diversity have become an essential part of every university and medical school’s mission statement. Yet, with such an emphasis on diversity, there is an evident absence of<br/>cultural competence education in the curricula of medical education. There is no clear answer of<br/>what is expected of physicians and no direct transitions for the different stages of medical<br/>training when it comes to cultural competence education. This is a vital issue, as there is a close<br/>relationship between the quality of patient care, patient adherence, and medical providers’ levels<br/>of cultural competence. This research analyzes the extent that cultural competence is taught at<br/>various points of the medical education cycle through a data analysis of an IRB approved<br/>questionnaire given to students within the medical education cycle and their value versus<br/>exposure of cultural competence.

Soccer is bar none, the most popular sport in the entire world. It is played, followed, and loved by virtually every single country on Earth. Despite this massive support for the sport which houses some of the world’s biggest names in the world, its shortcomings when dealing with issues of racial injustice and incidents of racist behavior have become more pronounced in recent years. Although this open discussion regarding racism within the sport has recently begun to sprout, its roots can be tied back to decades ago while continuing to the present day, with players, referees, coaches, fans, commentators, and more all involved on both sides of the issue. <br/> We found this topic to be most prevalent in today’s society after witnessing multiple shameful racist incidents that have occurred to some of the world’s biggest players throughout European football in 2019, as well as the recent ongoing fight for racial reform and increased awareness regarding racial injustice in the United States. By doing comprehensive research and<br/>analysis on such incidents that have occurred throughout the years we hope to raise more<br/>awareness regarding this subject that has plagued the beautiful game. In addition, we hope to<br/>offer ways to remedy the problem one step at a time, all while answering the tough, but necessary questions regarding what specifically should be done in the sport, that others have been afraid to talk about for far too long. Specifically, we wanted to mainly highlight the experience of black players, with a further discussion on other minority groups, in English and Italian football as these two leagues have been a part of the largest debate between how club traditions, player-fan interactions, league policies, and staff management have all affected the way we view the game as the endemic of racism within the sport is exacerbated.

Soccer is bar none, the most popular sport in the entire world. It is played, followed, and loved by virtually every single country on Earth. Despite this massive support for the sport which houses some of the world’s biggest names in the world, its shortcomings when dealing with issues of racial injustice and incidents of racist behavior have become more pronounced in recent years. Although this open discussion regarding racism within the sport has recently begun to sprout, its roots can be tied back to decades ago while continuing to the present day, with players, referees, coaches, fans, commentators, and more all involved on both sides of the issue. <br/> We found this topic to be most prevalent in today’s society after witnessing multiple shameful racist incidents that have occurred to some of the world’s biggest players throughout European football in 2019, as well as the recent ongoing fight for racial reform and increased awareness regarding racial injustice in the United States. By doing comprehensive research and analysis on such incidents that have occurred throughout the years we hope to raise more awareness regarding this subject that has plagued the beautiful game. In addition, we hope to offer ways to remedy the problem one step at a time, all while answering the tough, but necessary questions regarding what specifically should be done in the sport, that others have been afraid to talk about for far too long. Specifically, we wanted to mainly highlight the experience of black players, with a further discussion on other minority groups, in English and Italian football as these two leagues have been a part of the largest debate between how club traditions, player-fan interactions, league policies, and staff management have all affected the way we view the game as the endemic of racism within the sport is exacerbated.

The social determinants of health (SDOH) represent factors that impact the health and effectiveness/compliance of a treatment plan for a patient. The SDOH include such factors as economic stability, education, home and community context, access to healthcare, neighborhood and built environment, and personal behavior. The purpose of this study is to determine the extent of collection and integration of SDOH into clinical practice, and the usefulness of this information in medical decision making. Following a thorough literature review, an online survey was deployed to physicians and administrators around the country, with the aim of answering the following questions: 1) Do provider practices collect information on a patient's social determinants of health? 2) If yes, how is that information being used, if at all? 3) If not, what is preventing them from doing so? 4) Do the answers to questions 1-3 differ based on the type of payment model (Fee-for-Service or Capitation) to which the practice is subject? The results of the study suggest that fee-for-service payment environments present less incentive to use a patient's SDOH in medical decision making.

The Philippines relies on a vast biodiversity of fishes as a staple food, but like many countries around the globe, experiences severe “leakages” of contaminants and pollutants in the environment. In order to better understand the relationship between environmental pollutants and public health, this research project measured the concentration of pollutants in a commonly consumed local fish (Siganus fuscescens), and then evaluated the potential health risks of eating this fish based on estimated average consumer weight and consumption levels. Fish sampled from four different sites located in Negros Oriental, Philippines were analyzed for organic contaminants using gas chromatography and mass spectroscopy. Pollutants quantified included polycyclic aromatic hydrocarbons (PAHs), pesticides, phthalates, and polychlorinated biphenyl (PCBs). Across the four study sites, fishes from Manjuyod showed the highest frequency of detection of different pollutants. However, phthalates and PAHs were found in similar concentrations in all four sites, with fishes from Dumaguete showing the highest level of PCBs compared to the other sampled sites. The U.S. Environmental Protection Agency’s guide for fish contaminants pinpoints several health risks associated with the chronic ingestion of these contaminants. Based on estimated average body weights of Filipino adult men, adult women, and children, and various consumption levels, people who eat the fish at or above the national average consumption level may be at increased risk for chronic health outcomes, such as cancer and/or other adverse effects. Specifically, due to the high concentration of PCBs in Dumaguete, selected populations who eat local fish from this site may be at higher risk than the citizens who eat the fish from other sites at similar consumption rates. These results can help to inform local and national policies on water quality, waste disposal, and fish consumption advisory programs.

Cancer is a disease acquired through mutations which leads to uncontrolled cell division and destruction of normal tissue within the body. Recent increases in available cross-species data of cancer in mammals, reptiles, birds, and other vertebrates has revealed that the prevalence of cancers varies widely across species. Life-history theory suggests that there could be traits that potentially explain some of that variation. We are particularly interested in species that get very little cancer. How are they preventing cancer and can we learn from them how to prevent cancer in humans? Comparative oncology focuses on the analysis of cancer prevalence and traits in different non-human species and allows researchers to apply their findings to humans with the goal of improving and advancing cancer treatment. We incorporate the predictions that animals with larger bodies have evolved better cancer suppression mechanisms than animals with small bodies. Ruminants in the past were larger in size than modern day ruminants and they may have retained cancer defenses from their large ancestors. The strong cancer defenses and small body size combined may explain the low prevalence of cancer in Ruminants. This paper aims to evaluate the presence of benign and malignant neoplasia prevalence across multiple ruminant species following a time of dramatic decrease in body size across the clade. Our aim is to illuminate the potential impact that these shifts in body size had on their cancer prevalence as well as test the statistical power of other key life history variables to predict cancer prevalence.

Today, some modern zoos, aquariums, and similar animal-exhibiting institutions continue to shift their priorities toward a focus on the conservation of wildlife. Conservation challenges span a broad subject area. The focus that any institution chooses can vary greatly in terms of magnitude and measures of significance. Many modern zoos often choose to make global conservation a central institutional priority: conservation of biodiversity, habitat protection, species extinction, and more. Some institutions, however, set conservation priorities on a smaller scale, focusing on contributions that have a more indirect effect on wild species and habitats, such as the welfare of populations in captivity, raising public awareness of conservation missions, and conservation education. By comparing the institutional priorities of two organizations within the Association of Zoos and Aquariums (AZA), the Arizona-Sonora Desert Museum and the Phoenix Zoo, I explore how each institution manages its living collections and works toward its respective conservation mission. I interviewed members of each institution and analyzed the similarities and differences between the organizations based on their management of living collections, and how different mission statements might shape their work. This included investigating the focus each institution has on animal welfare, in situ and ex situ conservation, and maintaining public interest. This also required defining what conservation and welfare mean to each institution and how that affects the management of their living collections. From a literature review and interviews with representatives from each institution, I was able to determine that despite any differences in style or in the language of respective mission statements, each institution prioritizes connecting the public and conservation of biodiversity. While they employ different approaches - one institution takes a regional interest in the Sonoran Desert ecosystem and landscape; the other takes a more global approach to its experiences, exhibits, and collections - the core values and ultimately the vision remain the same. Conservation may serve as the primary motivator for both the Museum and the Zoo, but my thesis is that this rationale could not be realized by itself for these institutions. Rather, conservation as a core value relies upon the support of other critical institutional priorities working together. In this way animal welfare, public engagement, and conservation relate to one another as institutional values and create the impact that the zoo and museum have on their local communities, as well as on conservation as a whole.

Managing a work-home balance is a daunting task for any parent. It is often difficult to take leave from work to care for one’s family due to financial barriers, which simultaneously poses a threat to family development. Although many countries have parental leave policies in place to account for this, effectiveness of these policies vary by country. This study aims to find to what extent parental leave has an impact on the quality of life. In this study, quality of life was investigated by the rank of the country on the Happiness Index and through the lens of achieving sustainable family development, which was subsequently described to be reflected by a country’s governmental resources provided during parental leave, as well as the country’s Gender Inequality Index. Through a cross-cultural review of literature, it was found that there seems to be an indirect, complex correlation of parental leave to the quality of life, and external factors such as sociocultural ideals, gender inequality, and varying workplace practices have greater significance on quality of life.

Heliobacteria are an anaerobic phototroph that require carbon sources such as pyruvate, <br/>lactate, or acetate for growth (Sattley, et. al. 2008). They are known for having one of the <br/>simplest phototrophic systems, the central component of which is a Type I reaction center (RC) <br/>that pumps protons to generate the electrochemical gradient for making ATP. Heliobacteria <br/>preform cyclic electron flow (CEF) with the RC in the light but can also grow chemotropically in <br/>the dark. Many anaerobes like heliobacteria, such as other members of the class Clostridia, <br/>possess the capability to produce hydrogen via a hydrogenase enzyme in the cell, as protons can <br/>serve as an electron acceptor in anaerobic metabolism. However, the species of heliobacteria <br/>studied here, H. modesticaldum have been seen to produce hydrogen via their nitrogenase <br/>enzyme but not when this enzyme is inactive. This study aimed to investigate if the reason for <br/>their lack of hydrogen production was due to a lack of an active hydrogenase enzyme, possibly <br/>indicating that the genes required for activity were lost by an H. modesticaldum ancestor. This <br/>was done by introducing genes encoding a clostridial [FeFe] hydrogenase from C. thermocellum<br/>via conjugation and measuring hydrogen production in the transformant cells. Transformant cells <br/>produced hydrogen and cells without the genes did not, meaning that the heliobacteria ferredoxin <br/>was capable of donating electrons to the foreign hydrogenase to make hydrogen. Because the <br/>[FeFe] hydrogenase must receive electrons from the cytosolic ferredoxin, it was hypothesized <br/>that hydrogen production in heliobacteria could be used to probe the redox state of the ferredoxin <br/>pool in conditions of varying electron availability. Results of this study showed that hydrogen <br/>production was affected by electron availability variations due to varying pyruvate <br/>concentrations in the media, light vs dark environment, use acetate as a carbon source, and being <br/>provided external electron donors. Hydrogen production, therefore, was predicted to be an <br/>effective indicator of electron availability in the reduced ferredoxin pool.

The aim of this study was to explore cross-sectional and longitudinal aging differences in immediate and delayed visual and verbal memory abilities in individuals with Autism Spectrum Disorder (ASD) compared with neurotypicals (NTs). We measured hippocampal size, fornix fractional anisotropy (FA), and hippocampal and fornix freewater to understand how aging impacts memory structures. Longitudinal findings highlight vulnerabilities in immediate verbal memory and hippocampal volume, while cross-sectional findings indicate fornix freewater may increase at a faster rate in adults with ASD. Future research will examine cognitive and structural sex differences and will study how cognitive measures correlate with structural measures.