Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.

Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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ContributorsFinkbeiner, Ally (Author) / Sterner, Beckett (Thesis director) / Upham, Nate (Committee member) / Barrett, The Honors College (Contributor) / Historical, Philosophical & Religious Studies, Sch (Contributor) / Economics Program in CLAS (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description
The North American deer mouse, Peromyscus maniculatus, is the most widespread mammal on the continent. It is of interest to the public health sector as a known host of several viruses which are transmissible to humans and can cause illness, including the acute respiratory disease Hantavirus Pulmonary Syndrome (HPS). This

The North American deer mouse, Peromyscus maniculatus, is the most widespread mammal on the continent. It is of interest to the public health sector as a known host of several viruses which are transmissible to humans and can cause illness, including the acute respiratory disease Hantavirus Pulmonary Syndrome (HPS). This paper seeks to conduct a systematic review of existing literature on virus detection in wild P. maniculatus in order to develop an understanding of virus prevalence and distribution and identify potential areas of further research. Through the analysis of 22 studies published since 2010, it was found that detection effort has been concentrated on the American West with a focus on the spread of Sin Nombre virus, the causative agent of HPS. There are significant gaps in the existing literature both geographically and in regards to the types of viruses being sampled. Moving forward, a systematic approach to widespread sampling should be developed in order to better identify and minimize potential threats to human health.
ContributorsFinkbeiner, Ally (Author) / Sterner, Beckett (Thesis director) / Upham, Nate (Committee member) / Barrett, The Honors College (Contributor) / Historical, Philosophical & Religious Studies, Sch (Contributor) / Economics Program in CLAS (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

This thesis presents a systematic review of viruses found in the Peromyscus leucopus rodent species in North America. Various viruses cause serious illness in humans through contact with infected rodent urine, droppings, or saliva, or inhalation of dust contaminated with the virus, with Hantavirus pulmonary syndrome (HPS) being the most

This thesis presents a systematic review of viruses found in the Peromyscus leucopus rodent species in North America. Various viruses cause serious illness in humans through contact with infected rodent urine, droppings, or saliva, or inhalation of dust contaminated with the virus, with Hantavirus pulmonary syndrome (HPS) being the most severe manifestation. Therefore, studying their distribution in rodent populations can inform public health interventions to reduce the risk of transmission. Through a literature review and data analysis, this study found that studying the distribution of viruses in rodents can help identify areas where humans may be at higher risk of contracting the virus, inform public health interventions to reduce the risk of HPS transmissions, and better understand the ecology of the virus and its host species, which can, in turn, inform conservation efforts. Furthermore, monitoring the spread of viruses over time and across regions can help us better understand their epidemiology and potential for future outbreaks, which can inform surveillance and response efforts to mitigate the impact of the virus on human and animal health. Overall, this study highlights the importance of interdisciplinary approaches in addressing complex public health and conservation issues and underscores the need for continued research in this area.

ContributorsJain, Tanishq (Author) / Sterner, Beckett (Thesis director) / Upham, Nathan (Committee member) / Barrett, The Honors College (Contributor) / School of Sustainability (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

The North American deer mouse, Peromyscus maniculatus, is the most widespread mammal on the continent. It is of interest to the public health sector as a known host of several viruses which are transmissible to humans and can cause illness, including the acute respiratory disease Hantavirus Pulmonary Syndrome (HPS). This

The North American deer mouse, Peromyscus maniculatus, is the most widespread mammal on the continent. It is of interest to the public health sector as a known host of several viruses which are transmissible to humans and can cause illness, including the acute respiratory disease Hantavirus Pulmonary Syndrome (HPS). This paper seeks to conduct a systematic review of existing literature on virus detection in wild P. maniculatus in order to develop an understanding of virus prevalence and distribution and identify potential areas of further research. Through the analysis of 22 studies published since 2010, it was found that detection effort has been concentrated on the American West with a focus on the spread of Sin Nombre virus, the causative agent of HPS. There are significant gaps in the existing literature both geographically and in regards to the types of viruses being sampled. Moving forward, a systematic approach to widespread sampling should be developed in order to better identify and minimize potential threats to human health.

ContributorsFinkbeiner, Ally (Author) / Sterner, Beckett (Thesis director) / Upham, Nate (Committee member) / Barrett, The Honors College (Contributor) / Historical, Philosophical & Religious Studies, Sch (Contributor) / Economics Program in CLAS (Contributor) / School of Life Sciences (Contributor)
Created2023-05
Description

This study highlights the significance of zoonotic diseases, which make up almost 60% of infectious diseases in humans, and their origin from animals. Among mammalian viruses, primates, bats, and rodents have been identified as high-risk carriers. Within the rodent family Cricetidae, the species complex of Peromyscus eremicus, Peromyscus californicus, Peromyscus

This study highlights the significance of zoonotic diseases, which make up almost 60% of infectious diseases in humans, and their origin from animals. Among mammalian viruses, primates, bats, and rodents have been identified as high-risk carriers. Within the rodent family Cricetidae, the species complex of Peromyscus eremicus, Peromyscus californicus, Peromyscus fraterculus, and Osgoodomys banderanus have been found to play a crucial role in disease transmission. These four species are phylogenetically related and share similar physical appearances and ecological niches. They have been identified as carriers of several zoonotic diseases, including Hantavirus, Arenavirus, Yersinia pestis, and Flavivirus, with a history of spread to humans. Despite their implications for public health, many of these species remain understudied. Thus, this study aims to provide a systematic review of the existing literature on these four species to summarize the findings on virus prevalence and distribution. The review shows that sampling efforts have been uneven and recent efforts have been lacking, with potential undiscovered zoonotic diseases. The concentration of sampling efforts in California and gaps in the literature are concerning, especially with changing agriculture and climate change potentially affecting rodent communities.

ContributorsTariq, Muhamamad (Author) / Sterner, Beckett (Thesis director) / Upham, Nate (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor)
Created2023-05
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Description
Humans have evolved in many ways. Just look at how life for mankind has changed over the past few decades. It is amazing how different life can be in just a short amount of time. While it is evident that we have impacts of the environment, it should be just

Humans have evolved in many ways. Just look at how life for mankind has changed over the past few decades. It is amazing how different life can be in just a short amount of time. While it is evident that we have impacts of the environment, it should be just as evident that we impact the animals around us. However, there are a few subtle ways in which we impact the evolution of life.
Through man-made structures, human interference, artificial lights at night, and electromagnetic fields we have caused animals and insects to evolve and fit these new environments. While we tail the world around us to convince ourselves, the animals also living in these environments need to adapt to survive. In this essay, I will discuss how the affects mentioned above have cause crows, moths, snails, bobcats, blackbirds, mosquitoes, elephants, diurnal animals, fireflies, dung beetles, birds and bats to evolve. The adaptations these organisms made were caused by the subtle ways in which we have impact the landscapes around us.
ContributorsFikse, Sydney D (Author) / Sterner, Beckett (Thesis director) / Pfeifer, Susanne (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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Description
This thesis analyzes the implications of climate change for insect-borne diseases in humans, focusing especially on mosquitoes and ticks as the two most common vectors. I first introduce relevant background on climate change, arthropod vectors, and the diseases they carry, and the significance of vector-borne diseases for human health. I

This thesis analyzes the implications of climate change for insect-borne diseases in humans, focusing especially on mosquitoes and ticks as the two most common vectors. I first introduce relevant background on climate change, arthropod vectors, and the diseases they carry, and the significance of vector-borne diseases for human health. I report on current knowledge of spatial and temporal trends in most common mosquito and tick-borne diseases in the United States, with a detailed table provided in Appendix A. I then review how climatic variability is anticipated to cause profound changes in vector life cycles. In particular, the rise in global ambient temperatures is likely to be the primary driver of arthropod proliferation, although they are also sensitive to changes in humidity, carbon dioxide levels, and water levels. As regions warm, arthropods will be able to survive where they were not able to previously, potentially infecting more individuals. The incidence of several vector-borne diseases in the United States is predicted to increase in multiple states as climate change progresses. The World Health Organization predicts that in North America, Dengue Hemorrhagic Fever and Lyme disease will become the primary vector-borne diseases that are increasingly common (Githeko, et. al, 2000).
ContributorsKarjala, Sylvia (Author) / Sterner, Beckett (Thesis director) / Jevtic, Petar (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
This thesis explores the dynamics of zoonotic reservoirs in the Peromyscus genus, illuminating their critical function in the spread of zoonotic viruses and their public health consequences. Through analysis of research publications on viruses in Peromyscus species, this study articulates a framework for synthesizing diverse types of evidence, e.g. about

This thesis explores the dynamics of zoonotic reservoirs in the Peromyscus genus, illuminating their critical function in the spread of zoonotic viruses and their public health consequences. Through analysis of research publications on viruses in Peromyscus species, this study articulates a framework for synthesizing diverse types of evidence, e.g. about species-specific immune responses and ecological interactions, to determine reservoir host status. A comprehensive examination of the collected literature reveals significant gaps in the accepted meanings of "competence" and "reservoir," highlighting the intricacy of the ecology of disease. By integrating these insights with a reorganized spillover chart derived from Plowright et al. (2017) zoonotic spillover frameworks, the thesis provides a clearer understanding of transmission dynamics and advances conceptual foundations for a broader database of reservoir host species.
ContributorsKumari, Nikita (Author) / Sterner, Beckett (Thesis director) / Upham, Nathan (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / School of Art (Contributor)
Created2024-05