Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
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- Creators: Martin, Thomas
Description
There are problems in the breeding practices of miniature horses. This study seeks to determine the source of these detrimental outcomes based on an evaluation of primary attributes selected for by breeders and the lack of genetic information and understanding of these attributes. In order to do this a program model was created to test the effects of selection criteria on breeder behavior and the resultant foals of these crosses. Moving forwards this program will evolve into a database of the equine genome for different horses. This will allow breeders to input their horses and do faux crosses in order to decrease the incidence of negative and detrimental outcomes.
ContributorsDavis, Marissa Lynn (Author) / Oberle, Eric (Thesis director) / Martin, Thomas (Committee member) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The 1878 Treaty of Berlin sought to address the issue of minority rights in order to stabilize the interests of the Great Powers and the international order; however, in their formulation of a treaty intended to save the imperial component of the system, the European imperial powers not only gave one of their official acknowledgments to nationalist principles, but articulated a critique of the existing notion of state protection for ethnic minorities. This tentative but landmark modification of the imperial model of legitimacy suggested Europe or the world could consist of a host of sovereign nations. In so doing, it recognized the political, and ideological changes that nationalism demanded, changes that would reshape how national groups organize politically, culturally, and militarily. The logic of nationalism demanded that new boundaries, conceived on national lines be drawn, and they were drawn, both within the Austro-Hungarian and Ottoman Empires. The Treaty of Berlin led to the formation of Greater Bulgaria and Albania, and these new nationalities formed a initial answer to the European question of minority groups. The Treaty of Berlin is useful to examine in relation to its better-known and much more radical offspring, the Treaty of Versailles. Differences in the approach of either treaty provide a study in the lasting effects of soft power to resolve international conflict. The Great Powers met in Berlin to address a developing crisis in an attempt to avoid a destabilizing regional conflict through diplomatic and legal means, whereas the Paris Peace Conference met at Versailles to develop new order across Europe in the wake of the Great War. The Treaty of Versailles, sharply chiding the Central Powers as it promulgated a victor's peace, hoped to prevent future war by placing economic burdens on Germany. While the conference at Paris acknowledged the minority position, the overwhelming legal focus went to addressing developing nations and nationalisms in a way that was consistent with the beliefs of old imperial rule. The earlier Treaty of Berlin's relative emphasis on minority questions as logically antecedent to the disposition of nationalism becomes of highest significance in retrospect. It is this focused approach to addressing developing nationalism that makes the Treaty of Berlin an important point of discussion. It provides a precedent for how questions of minority rights should be addressed, and where it falls short of an answer on how conflict might be prevented, it explores how the tensions within the international system can exacerbate one another, as they did in the breakdown of diplomacy and law that to the First World War . This thesis aims to address how the triumph of nationalism as a model of state legitimacy almost immediately gave rise to the question of legal protection of minorities. The minority question only became more urgent as nationalists developed policies that practiced first passive, and then active exclusion of minority groups. While nationalism's relation to democratic rule seemed to solve the problems of representative government, it quickly forced the question of how legitimate representation was determined. Shifting notions of political legitimacy, unworkable empires, and heightened international rivalry formed a widening spiral of crisis that eclipsed the minority question, but this thesis supports the belief that the centrifugal force of conflict came out of the avoidance of addressing minority rights completely. Attempts were made through the twentieth century to mitigate conflict between people groups, but many failed to produce fully developed solutions, while many others favored the status quo, seemingly hoping that the question would answer itself. A study of the early history of the minority rights question helps us understand the national question in the old-new light of the international order and questions of international law. Given the conflicts that have arisen out of the relations between nations and the question of minority rights, the minority question is present in much of today's thinking about human rights and the maintenance of international order. Understanding the origins of minority rights and the factors considered in the early negotiations set to address the problem helps develop a deeper understanding of the of the interactions between nations and people today.
ContributorsGobble, Tyler Scott (Author) / Oberle, Eric (Thesis director) / Martin, Thomas (Committee member) / Aviation Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
It goes without saying that marriage, and the concept of two people staying together for the rest of their lives, is not easy. In today's society, divorce is something that is becoming more and more prominent among people. However, despite the divorce phenomenon there are still success stories of couples who last and manage to stick together despite the odds. It is difficult to measure the "successfulness" of any marriage due to the fact that so many different elements comprise them. However, there are endless assessments available to be used as tools for attempting measurement of success. A majority of them are related to measuring relationship quality in terms of individual satisfaction by focusing on each individual's happiness within the relationship. Obviously, every marriage is different and there are many things that can impact a couple's' likeliness to stay together such as the general circumstances surrounding their union and each partner's willingness to persevere. For instance, there are a variety of different factors that influence the overall success of marriages within and surrounding the United States Military. Such as physical proximity, frequency of communication, and a mutual desire to make the relationship work. Cultivating a relationship in which one partner is a service member and one partner is a civilian is stressful for both people involved. Specifically, the intense stress couples experience associated with deployment can often cause severe problems such as depression and anxiety that may lead to divorce or mental health problems later on down the road. Stressors specifically related to the deployment cycle can contribute to depression among both service members and their spouses. Most of these families face unique stressors through the course of military service and deployments, including frequent relocations and recon�gurations of the family system, ambiguous loss and fear for a loved one's safety, and high levels of stress and/or dysfunction among family members (Flake, Davis, Johnson, & Middleton, 2009; Huebner, Mancini, Wilcox, Grass, & Grass, 2007) Separation , unpredictable duty hours, and single parenting (parenting while the veteran is away either being deployed or on training courses) are just a few of the stressors that face partners of veterans on a regular basis (Padden, Connors & Agazio, 2011). Dr. John Gottman, the executive director of the Relationship Research Institute. has conducted extensive research regarding marital stability and divorce prediction on thousands of couples over the last forty years of his career. Using video cameras, heart monitors, and other biofeedback equipment, he and his colleagues have screened interviewed and tracked what couples experience during moments of conflict and closeness. Over the span of the last forty years, Dr. Gottman has created a theory he calls "The Four Horsemen of the Apocalypse". In the New Testament, the Four Horsemen of the Apocalypse are a metaphor marking the beginning of end times. Dr. Gottman's Four Horsemen on the other hand, are a metaphor marking the beginning of the demise of a marriage. The horsemen include criticism, contempt, defensiveness, and stonewalling. They are communication styles among couples that Dr. Gottman says can predict the end of a relationship. This notion holds true especially in the implication of military relationships. Focusing on the predictors of divorce, and inspecting the elements of these relationships in which the military is a condition of the union, discoveries can be made as to what makes these military relationships more difficult. An examination through the lens of Dr. Gottman's horsemen of the circumstances surrounding these unions in which deployment physically separates the two partners demonstrates how deployment in and of itself can cause couples to encompass each of the horsemen and eventually push them towards divorce. Throughout the course of this paper, the different elements that embody each of the four horsemen will be examined and analyzed as they pertain to the deployment process. Upon completion of the examination of these different factors, it can be suggested that deployment in its nature becomes the harbinger of the apocalypse. By encompassing all the different aspects of the first four original horsemen, and pushing military couples towards the behaviors that lead in the direction of divorce, deployment in and of itself can be thought of as predecessor, or harbinger of the apocalypse.
ContributorsSerdy, Taylor B (Author) / Martin, Thomas (Thesis director) / Mowzoon, Nura (Committee member) / W. P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
Each year, 30,000 patients obtain transplants. To prevent graft rejection, immunosuppressants such as tacrolimus are prescribed. Due to tacrolimus's narrow therapeutic range, a dose that is too low places patients at risk for transplant rejection, but too high of a dose leads to kidney failure. The de facto method for monitoring of transplant patient health is bimonthly blood draws, which are cumbersome, painful, and difficult to translate into urgently needed dosage changes in a timely manner. To improve long-term transplant survival rates, we propose a finger-prick sensor that will provide patients and healthcare providers with a measurement of tacrolimus, immune health (through IL-12), and kidney damage (through cystatin C) levels 100 times more frequently than the status quo. Additionally, patient quality of life will be improved due to reduction in time and pain associated with blood draws. Optimal binding frequencies for each marker were found. However, due to limitations with EIS, the integration of the detection of the three markers into one multimarker sensing platform has not yet been realized. To this end, impedance-time tests were run on each marker along with different antibodies, and optimal times of each marker were determined to be 17s, 6s, and 2s, for tacrolimus, cystatin c, and IL-12, respectively (n=6). The integration of impedance-time analysis with traditional EIS methodologies has the potential to enable multi-marker analysis by analyzing binding kinetics on a single electrode with respect to time. Thus, our results provide unique insight into possibilities to improve and facilitate detection of multiple markers not only for the sensor for solid organ transplant patients, but for the monitoring of patients with disease that also entail the observation of multiple markers. Furthermore, the use of impedance-time testing also provides the ability for another way to optimize accuracy/precision of marker detection because it specifies a particular time, in addition to a particular optimal binding frequency, at which to measure concentration.
ContributorsDoshi, Meera Kshitij (Author) / LaBelle, Jeffrey (Thesis director) / Steidley, Eric (Committee member) / Harrington Bioengineering Program (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
Leonardo's anatomical studies of the heart demonstrate the dependency of form and function on one another and that their combined activity leads to a comprehensive understanding of the cardiovascular system. While Leonardo was able to make incredible deductions regarding the heart's anatomy and physiology through the concepts of form and function, it is evident that his preconceptions hindered him from realizing the full scope of his individual findings. In this paper, I will evaluate the perception of anatomy, the manner in which anatomical knowledge was acquired, and the resultant traditional understanding of the cardiovascular system during Leonardo's lifetime. Leonardo's drawings of the heart will then be analyzed to determine what conclusions he was able to make regarding the heart's anatomy and physiology. Finally, I will compare Leonardo's findings to the modern understanding of the cardiovascular system. Because Leonardo's anatomical studies were hidden from the world for so long, many of his conclusions regarding the heart did not come to light before other individuals had already begun to reach them on their own. Although he made incredible leaps in the understanding of the cardiovascular system, he made little contribution to modern cardiology. Now Leonardo's work can only be examined retrospectively to determine the accuracies and inaccuracies of Leonardo's conclusions in comparison to our modern understanding.
ContributorsMulligan, Kelly Suzanne (Author) / Codell, Julie (Thesis director) / Martin, Thomas (Committee member) / School of Art (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
DescriptionMy main goal for my thesis is in conjunction with the research I started in the summer of 2010 regarding the creation of a TBI continuous-time sensor. Such goals include: characterizing the proteins in sensing targets while immobilized, while free in solution, and while in free solution in the blood.
ContributorsHaselwood, Brittney (Author) / LaBelle, Jeffrey (Thesis director) / Pizziconi, Vincent (Committee member) / Cook, Curtiss (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2011-12
Description
The Honors Thesis involved the use of vertically-aligned, piezoelectric nanowire sensor arrays configured by Dr. Henry A. Sodano and Dr. Aneesh Koka from the University of Florida, in order to acquire acceleration data. Originally, the project was focused on interfacing and calibrating the barium titanate (BaTio3) sensors to measure wall shear stress, a fluid dynamic characteristic. In order to gain an understanding of these novel piezoelectric sensors, the experiments performed by Sodano and Koka were to be investigated, replicated, and results reproduced. After initial trial phases, signals failed to be consistently measured from the sensors and the project's emphasis was re-defined. The outlined goals were 1) to re-design the initial system used for signal acquisition, 2) test the improved signal acquisition system, 3) successfully measure output signals from the BaTiO3 nanowire sensors, and 4) determine the cause for inconsistent signal measurements from the piezoelectric nanawire sensors. Following a detailed review of the previous experimental procedures and the initial signal acquisition system, an improved acquisition system was designed and its expected behavior was tested and verified. Despite the introduction of the improved acquisition system, voltage outputs were unable to be measured as a function of shaker table acceleration. It was impossible to verify the effect of the improved signal acquisition system on the measured BaTiO3 nanowire sensor output. Based on an analysis of data collected using a commercial 3-axis acceleromoeter, it is hypothesized that the BaTiO3 nanowire sensors were broken after the first experimental trial due to an excessively applied force from an external source (i.e. shaker table, improper handling during experimentation, and/or improper handling during transportation).
ContributorsThomas, Jonah (Author) / Frakes, David (Thesis director) / LaBelle, Jeffrey (Contributor) / Barrett, The Honors College (Contributor)
Created2014-05
Description
The purpose of this project was to examine the viability of protein biomarkers in pre-symptomatic detection of lung cancer. Regular screening has been shown to vastly improve patient survival outcome. Lung cancer currently has the highest occurrence and mortality of all cancers and so a means of screening would be highly beneficial. In this research, the biomarker neuron-specific enolase (Enolase-2, eno2), a marker of small-cell lung cancer, was detected at varying concentrations using electrochemical impedance spectroscopy in order to develop a mathematical model of predicting protein expression based on a measured impedance value at a determined optimum frequency. The extent of protein expression would indicate the possibility of the patient having small-cell lung cancer. The optimum frequency was found to be 459 Hz, and the mathematical model to determine eno2 concentration based on impedance was found to be y = 40.246x + 719.5 with an R2 value of 0.82237. These results suggest that this approach could provide an option for the development of small-cell lung cancer screening utilizing electrochemical technology.
ContributorsEvans, William Ian (Author) / LaBelle, Jeffrey (Thesis director) / Spano, Mark (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
Description
Batman is one of the most iconic characters in the history of popular culture. Ever since his creation in 1939, the character and his stories have gone through several changes. In my thesis, I explore and analyze the character within the nearly 20-year period in which he went through the most significant changes (1968-1986). Overall, these changes can be summarized as a shift from a lighthearted superhero consistently placed in campy situations to a dark and brooding vigilante who brutally dispatches his enemies. While analyzing the different versions of this character in this period of time, I reference the conclusions of two scholars: Travis Langley and Chuck Tate. Langley wrote a general psychological analysis of Batman by considering the essential characteristics of the character found in all forms of media. Tate concluded that Batman only uses hostile aggression for the sake of deriving pleasure form the pain he causes to criminals. After analyzing the comics as my primary sources, I have concluded that the general findings of Tate and Langley actually ignore the subtle details of changes in the humanity and self-awareness of the character through time. The lighthearted version of Batman in the late 60's is actually a self-obsessed narcissist, but as time passes, the darker mood of the character can be attributed to an increased acknowledgment of the destructive nature of his unique lifestyle. As the character grows more accepting of himself and his own reasons for continuing this lifestyle, his motivations become less self-centered. Overall, the central change of the character throughout time can be traced back to the status of his inner conflict between normal, human desires and the pure desire for constant vengeance.
ContributorsRivera-Passapera, Hiram Alfonso (Author) / Martin, Thomas (Thesis director) / Miller, April (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2015-05
Description
In order to address infant respiratory distress syndrome, this study attempts to develop and characterize a textile strain gauge fabricated with stainless steel, wool, elastic, and tencel. Faire Isle knitted patterns are investigated in order to create channels of conductivity for a linear sensor. The effect linear yarn density on linearity and sensitivity and hysteresis of the sensors is also investigated for sensor optimization. It was found that there was a significant difference between the patterned and non-patterned samples. The patterned sensors were found to have a lower range of resistance than the non-patterned sensors and a smaller average standard of deviation between measurements. The 7 tension, lower linear yarn density, elastic patterned sample was the only sample to not exhibit hysteresis after three trials as well as have a linear range from 11.5cm to 13cm where the sensor behaves in accordance with a linear transfer function.
ContributorsBrown, Shannon (Co-author) / Irimata, Lisa (Co-author) / LaBelle, Jeffrey (Thesis director) / Hanson, Erika (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2015-05