Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Displaying 1 - 10 of 54
Filtering by
- Creators: Harrington Bioengineering Program
- Creators: Walter Cronkite School of Journalism & Mass Comm
Description
Markov Chain Monte-Carlo methods are a Bayesian approach to predictive statistics, which takes advantage of prior beliefs and conditions as well as the existing data to produce posterior distributions of relevant parameters. This approach, implementable through the JAGS packaging in R, is promising for its impact on the diagnostics space, which is a critical bottleneck for pandemic planning and rapid response. Specifically, these methods provide the means to optimize diagnostic testing, for example, by determining whether it is best to test individuals in a certain locale once or multiple times. This study compares the expected accuracy of single and double testing under two specific conditions, a general and Icelandic test case, in order to ascertain the validity of MCMC methods in this space and inform decisionmakers and future research in the space. Models based on this platform may eventually be tailored to the priors of specific locales. Additionally, the ability to test multiple regimes of real or simulated data while maintaining uncertainty widens the pool of researchers that can impact the space. In future studies, ensemble methods investigating the full range of parameters and their combinations can be studied.
ContributorsSuresh, Tarun (Author) / Naufel, Mark (Thesis director) / Panchanathan, Sethuraman (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
When an individual is conceived there is a metaphorical roll of the dice. A game of chance is played with their genetics to which they cannot consent. Unlucky players could have inherited mild conditions such as chronic allergies to terrible diseases such as Cystic Fibrosis or Tay-Sachs. Controlling the genetics of an individual through the use of gene editing technology could be the key to ending this cycle of genetic diseases. Once detrimental diseases are now being cured through direct applications of genetic engineering. Even as we see the uses of genetic engineering technologies change the world, the more “sci-fi” applications have yet to be fully realized or explored. Editing hereditary genes before birth may have the ability to eliminate diseases from entire genetic lines, reduce the possibility for certain cancers and diseases, and perhaps even modify phenotypes in humans to create enhanced humans. Although this scientific field shows promise, it does have its reservations. Like any other scientific field, its ability to benefit humanity depends on its use.
ContributorsSchuler, Jacob (Co-author) / Silva, Anthony (Co-author) / Brian, Jennifer (Thesis director) / Ross, Christian (Committee member) / Harrington Bioengineering Program (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Homeopathy is a brand of alternative medicine that has enjoyed a unique form of regulation for many years. This work aims to understand the regulation of homeopathic drugs in the United States by performing a literature review focused on three fronts: (i) homeopathy (theory, history in the United States and criticisms), (ii) U.S Food and Drug Administration (history and relationship to homeopathy), and (iii) interpretation of the law through reading guidance documents and the Code of Federal Regulations.
In 2015, the FDA began a process to reevaluate and update the regulations surrounding homeopathic products to better fit their present risk-based model. Past regulations were set in 1938; and as the world evolved, these have been found to set inadequate standards. By reviewing the agency’s guidance drafts and core regulatory documents, we come to understand that these changes are motivated by a desire for homeopathic remedies to follow high standards that apply to other products for the benefit of the U.S. consumers. FDA has made significant advances by proposing new Guidances on homeopathic products, listening to homeopathic community and consumers, and withdrawing the Compliance Policy Guide 400.400 issued in 1988.
We recommend for homeopathic manufacturers and practitioners to see the FDA as an ally and cooperate fully with the proposed changes for the regulation the agency gives out. Doing so will give the homeopathic community the best chance at continuing to sell their products and reach their consumers in the United States. In the same token, the FDA should do their best to involve homeopathic professionals in some way in this regulatory process, to encourage participation and compliance by the broader homeopathic community. Doing so ensures a climate of teamwork among different facets of the medical community in the United States.
In 2015, the FDA began a process to reevaluate and update the regulations surrounding homeopathic products to better fit their present risk-based model. Past regulations were set in 1938; and as the world evolved, these have been found to set inadequate standards. By reviewing the agency’s guidance drafts and core regulatory documents, we come to understand that these changes are motivated by a desire for homeopathic remedies to follow high standards that apply to other products for the benefit of the U.S. consumers. FDA has made significant advances by proposing new Guidances on homeopathic products, listening to homeopathic community and consumers, and withdrawing the Compliance Policy Guide 400.400 issued in 1988.
We recommend for homeopathic manufacturers and practitioners to see the FDA as an ally and cooperate fully with the proposed changes for the regulation the agency gives out. Doing so will give the homeopathic community the best chance at continuing to sell their products and reach their consumers in the United States. In the same token, the FDA should do their best to involve homeopathic professionals in some way in this regulatory process, to encourage participation and compliance by the broader homeopathic community. Doing so ensures a climate of teamwork among different facets of the medical community in the United States.
ContributorsRobayo, Juan Pablo (Author) / Pizziconi, Vincent (Thesis director) / Feigal, David (Committee member) / Frow, Emma (Committee member) / School of International Letters and Cultures (Contributor) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Tiger Woods’ adultery scandal was one of the most widely covered sports stories of the 2000s, in part because of how famous he was as a person and athlete. But the scandal and Tiger’s handling of it provided public relations professionals one of the most relevant crisis communications case studies in the history of sports. This case study is split into three sections; pre-scandal, the scandal itself and then his road to recovery. The case study is accompanied by an essay analyzing Woods’ crisis communications and image restoration strategies.
ContributorsVatti, Rayan (Author) / Hass, Mark (Thesis director) / Hege, Kristen (Committee member) / Walter Cronkite School of Journalism & Mass Comm (Contributor, Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
When you think of actors, you probably think of the glitz and glam of Hollywood. It is a career many desire to have because of this initial perception. Who does not want to live the lavish life of an actor? Who does not want to get paid to basically play dress up? The truth is acting is much more, and less, than that. In fact, there are almost no two actors with the same exact journey to where they are. The career itself is very subjective, which is quite the scary thought to many including myself. Since I was a kid, acting is all I wanted to do. However, I have also always been someone who enjoys stability and consistent next steps, which is why I have been terrified at the idea of pursuing acting for so long. It is not a career that guarantees success. It is not even a career that has one definition of success. What is not shown behind the flashing lights and the glamour is what it truly takes to “make it”. Like I said, there are different variations of “making it” as well. Because of this idea that a career in acting is not all one thing, I wanted to find the commonalities. Are there things anyone who wants to be an actor, whether it is theater, film, television, or commercial acting, can do to increase their chances for success? What are the steps necessary to be taken seriously in this industry? In this thesis, I am going to explore the intricacies of this career to try to answer these questions.
ContributorsBrook, Loza H (Author) / Collis, Adam (Thesis director) / Espinosa, Micha (Committee member) / School of Film, Dance and Theatre (Contributor) / Walter Cronkite School of Journalism & Mass Comm (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
A major challenge with tissue samples used for biopsies is the inability to monitor their molecular quality before diagnostic testing. When tissue is resected from a patient, the cells are removed from their blood supply and normal temperature-controlled environment, which causes significant biological stress. As a result, the molecular composition and integrity undergo significant change. Currently, there is no method to track the effects of these artefactual stresses on the sample tissue to determine any deviations from the actual patient physiology. Without a way to track these changes, pathologists have to blindly trust that the tissue samples they are given are of high quality and fit for molecular analysis; physicians use the analysis to make diagnoses and treatment plans based on the assumption that the samples are valid. A possible way to track the quality of the tissue is by measuring volatile organic compounds (VOCs) released from the samples. VOCs are carbon-based chemicals with high vapor pressure at room temperature. There are over 1,800 known VOCs within humans and a number of these exist in every tissue sample. They are individualized and often indicative of a person’s metabolic condition. For this reason, VOCs are often used for diagnostic purposes. Their usefulness in diagnostics, reflectiveness of a person’s metabolic state, and accessibility lends them to being beneficial for tracking degradation. We hypothesize that there is a relationship between the change in concentration of the volatile organic compounds of a sample, and the molecular quality of a sample. This relationship is what would indicate the accuracy of the tissue quality used for a biopsy in relation to the tissue within the body.
ContributorsSharma, Nandini (Co-author) / Fragoso, Claudia (Co-author) / Grenier, Tyler (Co-author) / Hanson, Abigail (Co-author) / Compton, Carolyn (Thesis director) / Tao, Nongjian (Committee member) / Moakley, George (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This thesis explores the introduction of Virgil Ortiz’s traditional Cochiti pueblo ceramic techniques and iconic imagery into the world of contemporary atmospheric high fired ceramics. Virgil is a multidimensional artist who has been working in ceramics since the age of 12, practicing the traditional hand building and decoration methods of his ancestral pueblo (1 traditional work) . In recent years, Virgil has begun to explore the use of modern materials and firing techniques in order to further his work and break into the contemporary ceramics community (2 modern materials). Virgil’s style is very figurative, sculpting human and human-like figures, and illustrating large vessels in the Cochiti traditional style, while incorporating his own characters, story lines and social commentaries.
Virgil and I met in 2019 while Virgil was performing a ceramics demo at the ASU Ceramics facilities. We collaborated on Virgil’s first line of completely handmade functional wares for his collaborative show at the ReVOlt gallery for Indian Market, Santa Fe 2019. In 2020, Virgil came to ASU as a visiting artist faculty and began work on larger pieces using more sculptural clays and exploring internal support structures under the guidance of myself and artist Ben Jackel. Seeing this large work and the opportunity to build on this, renowned art critic and appraiser Peter Held brought myself and Virgil to Reitz Ranch Center for Ceramic Arts, the former studio and home of Don Reitz. Don was an American master, building huge vessels and sculptures and firing them in salt, soda and wood kilns built on his property. He built a particularly larger Anagama style kiln, deemed the Reitz-agama, which measures 60in tall and 30 feet deep, specifically to be able to wood fire his massive wares. Don’s work is visceral and emotional, made with a heavy hand and minimally glazed, allowing for the buildup of wood ash and salt from the atmospheric firings to complete their surfaces. The ranch still holds all of his kilns, and hundreds of his pieces from years of success and failures. The owner of the ranch Sheryl Leigh-Devault, and Don’s former assistant Ben Roti, invited Virgil and I up to work at the ranch any time we wanted during this visit, and due to the closures of ASU studios and a desire to push our work together further than we ever had before, we orchestrated a week visit. This week visit developed into two weeks, and had since developed further into a one and a half month short term quarantine residency.
Virgil and I met in 2019 while Virgil was performing a ceramics demo at the ASU Ceramics facilities. We collaborated on Virgil’s first line of completely handmade functional wares for his collaborative show at the ReVOlt gallery for Indian Market, Santa Fe 2019. In 2020, Virgil came to ASU as a visiting artist faculty and began work on larger pieces using more sculptural clays and exploring internal support structures under the guidance of myself and artist Ben Jackel. Seeing this large work and the opportunity to build on this, renowned art critic and appraiser Peter Held brought myself and Virgil to Reitz Ranch Center for Ceramic Arts, the former studio and home of Don Reitz. Don was an American master, building huge vessels and sculptures and firing them in salt, soda and wood kilns built on his property. He built a particularly larger Anagama style kiln, deemed the Reitz-agama, which measures 60in tall and 30 feet deep, specifically to be able to wood fire his massive wares. Don’s work is visceral and emotional, made with a heavy hand and minimally glazed, allowing for the buildup of wood ash and salt from the atmospheric firings to complete their surfaces. The ranch still holds all of his kilns, and hundreds of his pieces from years of success and failures. The owner of the ranch Sheryl Leigh-Devault, and Don’s former assistant Ben Roti, invited Virgil and I up to work at the ranch any time we wanted during this visit, and due to the closures of ASU studios and a desire to push our work together further than we ever had before, we orchestrated a week visit. This week visit developed into two weeks, and had since developed further into a one and a half month short term quarantine residency.
ContributorsSmith, Andrew Walton Lee (Author) / Chung, Samuel (Thesis director) / Ortiz, Virgil (Committee member) / Harrington Bioengineering Program (Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In terms of overall athleticism, other than the obvious extremities that take on more skillful duties in performance (arms, legs, fingers ie.), the back, specifically lower, is pivotal in athletic movement. The main bolstering force in the lower back is the lumbar vertebrae, which on the upper end are connected to the thoracic portion of the spine, and on the lower end transform into the various processes of the sacrum. The lower back is highly involved in bending and stabilizing during athletic movement, while also being favorably responsible for not only producing but absorbing force as well. Men’s Football has the highest rate of occurrence in injuries compared to all other collegiate sports (Hassebrock 2019). This is a product of the various specificities of the game of football such as groundbreaking speed and strength, along with some psychological group-centered constructs. In survey findings, 83% healthcare professionals say that the best active treatment plan is strengthening the core muscles. While in terms of natural and technological treatments like acupuncture, contrast immersion, and electrical stimulation, there wasn’t a definitive methodology proven to be superior to the others. Allowing for the healthcare professional to be creative in their combination of treatments, as long as core strengthening is primarily targeted.
ContributorsWilliams, Kyle Ellis (Author) / Vernon, Brent (Thesis director) / Chhabra, Anikar (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this project was to interview eleven Hubert H. Humphrey Fellows at the Walter Cronkite School at Arizona State University through a podcast series titled “The Global Journalist Roundtable”. During a two month period, I interviewed the eleven Fellows and through a keyword analysis of the transcripts of each interview, I determined several themes which according to the Fellows were important aspects of global media. Those themes were education, innovation, social media as a disrupter to news verifiability, polarization, censorship, the importance of truthful news, and leadership. The reason for interviewing the Humphrey Fellows specifically was due to my sheer curiosity, respect, and admiration for them as professionals in the global media industry.
ContributorsEverett, William (Author) / Silcock, William (Thesis director) / Barrett, Marianne (Committee member) / Walter Cronkite School of Journalism & Mass Comm (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Preeclampsia is a condition which arises during pregnancy and can lead to serious, even fatal, complications for the mother and baby. Annually, preeclampsia is responsible for about 50,000 total deaths worldwide, and countless other complications for both the mother and fetus. While high blood pressure and protein in the urine are key features, symptoms vary widely, and thus understanding, diagnosing, and treating the condition is of paramount importance. Due to the correlation between preeclampsia and high blood pressure, multiple groups have studied the role of angiogenic growth factors and preeclampsia. We performed an advanced PubMed search to select studies with both preeclampsia and VEGF, a key growth factor for angiogenesis, in the title. The results of examining a total of 65 articles led to the formation of this review article to articulate the studies as a whole and state of the research on VEGF and preeclampsia to date.
ContributorsBoos, Kelsey (Author) / Burnsed, Olivia (Thesis director) / Vernon, Brent (Committee member) / Collins, Jason Mitchell (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05