Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Displaying 1 - 3 of 3
Description
Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with DRSP, the impact of DRSP on cognition, especially in reference to learning and memory, is not well understood. However, it is imperative to fully understand the cognitive effects of DRSP, both alone and in combination with EE (as taken in a combined oral contraceptive [COC]), so that women and their physicians can make a fully-informed decision when deciding to take a DRSP-containing COC. Study 1 examined the effects of three doses of DRSP in order to determine the optimal dose for combining with EE, and found that the medium dose of DRSP (30 µg/day) enhanced spatial working memory performance. In Study 2, the medium dose of DRSP from Study 1 was combined with low (0.125 µg/day) and high (0.3 µg/day) doses of EE to examine the effects of DRSP as taken with EE in a COC. The results from Study 2 indicated that when DRSP was combined with a low, but not high, dose of EE, spatial working memory impairments were seen at the highest working memory load. Anxiety-like behavior was evaluated using the OFT, and DRSP was shown to decrease measures of anxiety-like behavior. Additionally, while treatment with a high dose of EE decreased several measures of anxiety-like behavior, a low dose of EE did not, suggestive of a dose response. Taken together, the findings presented from both studies suggest that some of the cognitive effects of the combination of DRSP with EE are different than those of either hormone administered on its own. Further exploration in a preclinical, ovary-intact animal model is a next step to fully understand these effects in the translational context of a contraceptive, given that women taking an EE-DRSP combination are typically ovary-intact.
ContributorsPoisson, Mallori Louise (Author) / Bimonte-Nelson, Heather (Thesis director) / Doane, Leah (Committee member) / School of Nutrition and Health Promotion (Contributor) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
The purpose of this study was to determine the relationship between extracurricular activities and self-regulation in 400 five year old twin children. Extracurricular activities were assessed using the Health and Behavior Questionnaire, and self-regulation was assessed using the Children's Behavior Questionnaire. While there initially was a significant correlation between extracurricular activities and self-regulation, that correlation became non-significant when controlling for SES and sex in a mixed model regression model. Nearly all of the children who did not participate in extracurricular activities came from lower SES families, leading to a lack of a "control group" for the high SES families. When only taking into account the lower SES half of the sample, the correlation between extracurricular activities and self-regulation became stronger and the correlation between SES and self-regulation became non-significant. Extracurricular activities do appear to promote self-regulation in children coming from low SES families, yet their effects on children coming from high SES families is still unknown.
ContributorsMcdonald, Lauren Nicole (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Doane, Leah (Committee member) / Chemical Engineering Program (Contributor) / W. P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
Individuals with strong broad social motives (BSM) place high personal value on social activities and are at increased risk for heavy drinking. Those with strong BSM who also perceive that college students are heavy drinkers (high descriptive norms) might be particularly susceptible to increases in alcohol use during the transition to college, and may be likely to drink for social facilitation (social drinking motives). To test these hypotheses, we examined a mediated moderation model testing interactive effects of BSM and descriptive norms (perceptions of drinking in college) on drinking behavior, mediated by social drinking motives. Data were from 426 incoming college students and analyses were based on a subsample of 218 who reported drinking behavior at either time point. Results indicated that BSM interacted with descriptive norms to predict increases in social drinking motives from high school to college and social drinking motives in turn predicted increases in alcohol use. Probing this interaction revealed that those with high BSM and high descriptive norms experienced greater increases in social drinking motives than those with low descriptive norms. Tests of moderated indirect effects indicated that effects of BSM on drinking behavior through social drinking motives were also stronger among those with high descriptive norms. These results identify a particularly high risk group for changes in alcohol use during an important developmental period. This may have important implications for prevention and intervention methods which can attenuate college alcohol use by targeting individuals with strong BSM who perceive heavy drinking among college peers.
ContributorsCanning, Jessica Ryan (Author) / Corbin, William (Thesis director) / Glenberg, Arthur (Committee member) / Doane, Leah (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12