Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Filtering by
- Creators: College of Health Solutions
Eosinophil peroxidase (EPX) is a marker of eosinophilic inflammation in allergic diseases. Currently, measuring EPX in nasal swabs as a surrogate for airway eosinophil levels is completed using a gold standard enzyme-linked immunosorbent assay (ELISA) lab test. The purpose of this project was to develop and validate a novel lateral flow assay (LFA) that measures EPX with the same sensitivity and range of detection as the gold standard EPX ELISA, but that can be efficiently used in clinical settings. The results of this project show that the EPX LFA is a promising method for measuring EPX in nasal swab samples. While future studies are needed for further validation, the EPX LFA could provide rapid point-of-care EPX measurements for clinicians and patients suffering with eosinophil-associated diseases.