Barrett, The Honors College Thesis/Creative Project Collection
Barrett, The Honors College at Arizona State University proudly showcases the work of undergraduate honors students by sharing this collection exclusively with the ASU community.
Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.
Displaying 1 - 10 of 36
Description
The inherent risk in testing drugs has been hotly debated since the government first started regulating the drug industry in the early 1900s. Who can assume the risks associated with trying new pharmaceuticals is unclear when looked at through society's lens. In the mid twentieth century, the US Food and Drug Administration (FDA) published several guidance documents encouraging researchers to exclude women from early clinical drug research. The motivation to publish those documents and the subsequent guidance documents in which the FDA and other regulatory offices established their standpoints on women in drug research may have been connected to current events at the time. The problem of whether women should be involved in drug research is a question of who can assume risk and who is responsible for disseminating what specific kinds of information. The problem tends to be framed as one that juxtaposes the health of women and fetuses and sets their health as in opposition. That opposition, coupled with the inherent uncertainty in testing drugs, provides for a complex set of issues surrounding consent and access to information.
ContributorsMeek, Caroline Jane (Author) / Maienschein, Jane (Thesis director) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Breast cancer affects hundreds of thousands of women a year in the United States, and kills tens of thousands. African-American women experience a lower incidence of breast cancer, yet they die at twice the rate of Caucasian women. This disparity demonstrates the ineffectiveness of mammography at decreasing mortality in women at higher risk of late stage diagnosis. In this paper I argue that the continued support of the predominating idea that the benefits of mammograms strictly outweigh their negative effects may be a factor in the continued racial disparity in breast cancer mortality between African-American and Caucasian women. In addition, I will argue that mammograms are less effective for African American women because they are predisposed to later stage diagnosis and the accompanying poorer mortality prognosis due to higher-risk environments caused by varied socio-political status. My claims are supported by studies of incidence rates, survivorship versus mortality rates, screening usage rates, late stage and early stage diagnosis rate, tumor type, and the effects of socioeconomic status on stage of diagnosis. In particular, mortality rates have not decreased parallel with increased mammogram usage, especially in African-American women. Although early stage diagnosis has drastically increased, late stage-diagnosis remains unchanged and higher in African-American women. Tumor types vary by race, and African American women tend to have tumors that are highly prolific and more likely to be metastatic. Socioeconomic factors are more of a marker for breast cancer disparities than race, however race and socio-political structures that embody racism are often intersected.
ContributorsHuper-Holmes, Chloe Lynn (Author) / Lynch, John (Thesis director) / Brian, Jennifer (Committee member) / Barrett, The Honors College (Contributor) / School of Human Evolution and Social Change (Contributor) / School of Life Sciences (Contributor)
Created2015-05
Description
The first global estimate of maternal mortality in 1985 revealed that over half a million women die each year due to pregnancy related causes. Although a relatively small figure compared to the deaths attributed to such diseases as malaria and HIV, this was new data. New data meant attraction from powerful international agency leaders, which eventually led to the formation of a global effort called the Safe Motherhood Initiative (SMI). In turn, the global SMI provided the framework for the World Health Organization's (WHO) Millennium Development Goal 5 (MDG 5). Both of these global campaigns, which were largely implemented through advocacy efforts, adopted time sensitive goals aimed specifically to decrease maternal mortality. Although the placement of maternal health on the public health agenda was an extraordinary accomplishment for women's health advocates, a historical examination of safe motherhood efforts will reveal that these advocacy techniques would not keep maternal health on the public health agenda. Over two decades of unsuccessful efforts to reduce maternal mortality have shown that advocacy efforts are not the answer to actually decreasing maternal mortality ratios. Due to the intrinsic difficulties in measuring maternal mortality, and the public health sector's emphasis in prioritizing the political agenda based on such measurements, maternal health has arguably fallen in last place on the agenda. This thesis will explore how the concern for mothers influenced the formation of MDG 5, and how MDG 5 has been translated into local practices. A case study of the Pan American Health Organization's advocacy effort also called the Safe Motherhood Initiative explores the underlying, culturally complex problems that are hindering progress of MDG 5. The results show that the lack of comprehensive reproductive health services for women is not only due to poor health systems in place, which is what many safe motherhood 5 efforts have attempted to address, but also due to cultural traditions and laws on sexual and reproductive health forbidding women to obtain the care they need to survive.
ContributorsAntonios, Nathalie (Author) / Hurlbut, Ben (Thesis director) / Brian, Jennifer (Committee member) / Ellison, Karin (Committee member) / Barrett, The Honors College (Contributor)
Created2013-12
Description
A fundamental component of Transhumanism, radical life extension is the process of utilizing ever increasing technologies to further extend the average life span of humans. This iterative process has continued to increase in speed since the digital age. As society develops a larger knowledge base, and scientific fields combine their knowledge bases, the capability of medical professionals continues to increase at an exponential rate. Through an understanding of these technological trends the social, legal, logistical and economic implications can be better understood. Scenarios can be used to better categorize these implications based on the evolution of these technologies. By considering biological, non-biological and linear life extension technologies a broad analysis of the varied implications can be constructed. Based on these scenarios one can conclude radical life extension technologies will have significant impacts on the current social definitions of what it means to be human and how society organizes itself. Continued research towards radical life extension technologies comes with high social implications which must be considered in tandem.
ContributorsLightholder, Jack Anthony (Author) / Allenby, Braden (Thesis director) / Brian, Jennifer (Committee member) / Barrett, The Honors College (Contributor) / Computer Science and Engineering Program (Contributor)
Created2015-05
Description
Characterization of particulate process and product design is a difficult field because of the unique bulk properties and behaviors of particles that differ from gasses and liquids. The purpose of this research is to develop an equation to relate the angle of repose and flowability, the ability of the particle to flow as it pertains to particulate processes and product design. This research is important in multiple industries such as pharmaceuticals and food processes.
ContributorsNugent, Emily Rose (Author) / Emady, Heather (Thesis director) / Marvi, Hamidreza (Committee member) / Materials Science and Engineering Program (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Chemical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The goal of this thesis is designing controllers for swarm robots transport a payload over inclines. Several fields of study are related to this study, including control theory, dynamic modeling and programming. MATLAB, a tool of design controller and simulation, is used in this thesis.
To achieve this goal, a model of swarm robots transportation should be designed, which is cruise control for this scenario. Secondly, based on free body diagram, force equilibrium equation can be deduced. Then, the function of plant can be deduced based on cruise control and force equilibrium equations. Thirdly, list potential controllers, which may implement desired controls of swarm robots, and test their performance. Modify value of gains and do simulations of these controller. After analyzing results of simulation, the best controller can be selected.
In the last section, there is conclusion of entire thesis project and pointing out future work. The section of future work will mention potential difficulties of building entire control system, which allow swarm robots transport over inclines in real environment.
To achieve this goal, a model of swarm robots transportation should be designed, which is cruise control for this scenario. Secondly, based on free body diagram, force equilibrium equation can be deduced. Then, the function of plant can be deduced based on cruise control and force equilibrium equations. Thirdly, list potential controllers, which may implement desired controls of swarm robots, and test their performance. Modify value of gains and do simulations of these controller. After analyzing results of simulation, the best controller can be selected.
In the last section, there is conclusion of entire thesis project and pointing out future work. The section of future work will mention potential difficulties of building entire control system, which allow swarm robots transport over inclines in real environment.
ContributorsShe, Hanyu (Author) / Berman, Spring (Thesis director) / Marvi, Hamidreza (Committee member) / Mechanical and Aerospace Engineering Program (Contributor, Contributor) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The purpose of this thesis project is to analyze the legalization of physician-assisted suicide (PAS) as an option for the terminally ill in the United States from a rule-utilitarian perspective. The moral theory of utilitarianism is a consequentialist theory that judges the moral permissibility of an action or rule based on the best possible outcomes. Rule-utilitarianism conforms an action to an articulated moral rule that leads to the greatest good whereas act-utilitarianism only considers the best possible consequences on a case-by-case basis. Since legalization of PAS is a policy that requires passage of laws, rule-utilitarianism is more appropriate compared to act-utilitarianism. Euthanasia is a controversial topic worldwide that dates as far back as the 5th century BC with the Greeks and Romans. Comparing the euthanasia then and now, the nations are slowly but surely reconsidering the policies regarding PAS. There are both benefits and harms that the paper addresses. The possible benefits include the prevention of elongation of suffering, both physically and psychologically, respect for the patient autonomy, the right to die with dignity, and the decriminalization of the innocents. The potential harms include undermining the integrity of the medical profession and the aim of medicine, violation of the Hippocratic Oath, targeting of the vulnerable population, unmotivating the efforts to develop and improve better palliative and hospice care, and the slippery slope argument, which implies that the legalization of PAS would eventually set the precedence to legalizing voluntary active euthanasia and nonvoluntary euthanasia. Overall, the moral calculus that the paper provides comes to the conclusion that the benefits outweigh the harms.
ContributorsYang, Jae Hyeok (Author) / Manninen, Bertha (Thesis director) / Brian, Jennifer (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
The rate of cancer incidence is a morbid figure. Twenty years ago, 1 in 2 men and 1 in 3 women were predicted to be afflicted by cancer throughout their lifetime (Cancer Facts & Figures- 1998). In 2017, the rate remains the same ("Cancer Statistic Center"). Every year, more people are affected by cancer, which is a physiologically, psychologically, emotionally and socially devastating disease. And yet the language and metaphors we use to describe cancer focus our attention on the "fight" of the heroic individual against the brutal disease or on finding a cure. Despite this narrow rhetoric, there are many meaningful, supportive, and palliative measures designed to substantively and holistically care for cancer patients, beyond their medical treatment. Many of these interventions help the patient feel supported (and less alone in this "battle") by building robust communities. In this thesis, I argue the summer camps for children affected by cancer are meaningful interventions that offer palliative care throughout their treatment by creating support networks with peers going through similar medical procedures. Drawing on anecdotal evidence from three cancer camps and a detailed literature review of a subset of palliative interventions designed to promote well-being, this thesis proposes a new model for a summer camp that focuses on emotional processing emotional expression, positive psychology in order to improve palliative care for cancer patients.
ContributorsPearce, Spencer Taylor (Author) / Miller, April (Thesis director) / Brian, Jennifer (Committee member) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
This thesis elucidates the responsibility of the pharmaceutical industry for the current opioid epidemic, an epidemic which caused over 40,000 American deaths in 2016 alone. Twenty years prior, Purdue Pharma unleashed an extended-release formulation of the opioid oxycodone: OxyContin. With this, Purdue began a highly aggressive advertising campaign with the primary intention of guaranteeing the success of this drug; however, in doing so, they often neglected to ensure that the information they were propagating was wholly accurate. Previous reform attempts aimed at mollifying this crisis have ultimately fallen short, as they have failed to recognize the true extent of Purdue Pharma's involvement, especially with regard to the underlying issues that led to the initiation and progression of the epidemic. Future improvements should be targeted at the reform of regulatory agencies and insurance companies, as well as the cultural attitudes regarding pain and pain treatment that have been cultivated over the last several years. Ultimately, however, these reforms will likely prove to be insufficient unless the failings of the current healthcare system, including the pharmaceutical industry, are also taken into account.
ContributorsOzeran, Rachel Hoku Lii (Author) / Fong, Benjamin (Thesis director) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder that is becoming increasingly common. Autism does not yet have a known etiology, nor a definitive diagnostic test, thus making diagnosis a difficult and rarely uniform task. Currently, ASD is behaviorally diagnosed based on criteria defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders (DSM). Recently, a change was made in the criteria from more lenient criteria in DSM-IV-TR, to more narrow criteria laid out by the DSM-V, which supersedes the DSM-IV-TR. This drastic change raised many questions and debates about which set of criteria are better. The more lenient criteria offers a more inclusive diagnosis giving greater access to therapies; while the narrow diagnostic criteria excludes some individuals, creating a more uniform diagnosis that's easier to use in research. This thesis analyzes the change in diagnostic criteria from the DSM-IV-TR to the DSM-V and the effects of these changes on the practices of diagnosis. In addition, it explores the implications of this change for the families of children with autism and for those involved in autism research, examining their respective opinions and interests pertaining to narrow verses broad diagnostic criteria. Building on this analysis, the thesis offers recommendations about diagnostic criteria should be set. It argues that the wellbeing of patients takes priority over the interests of researchers, and thus diagnosis should be done in a way that offers the best prognosis for all children who suffer from autistic symptoms.
ContributorsBremer, Michelle Nichole (Author) / Hurlbut, Ben (Thesis director) / Robert, Jason (Committee member) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12