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Barrett accepts high performing, academically engaged undergraduate students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project which is an opportunity to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is supervised and defended in front of a faculty committee. Students are able to engage with professors who are nationally recognized in their fields and committed to working with honors students. Completing a Barrett thesis or creative project is an opportunity for undergraduate honors students to contribute to the ASU academic community in a meaningful way.

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Description
Glioblastoma is one of the leading types of brain cancer leading to patient death. To combat this type of cancer, many different types of imaging are used to analyze and treat glioblastomas. Still, magnetic resonance imaging, computed tomography, and positron emission tomography are the most commonly used imaging methods. In

Glioblastoma is one of the leading types of brain cancer leading to patient death. To combat this type of cancer, many different types of imaging are used to analyze and treat glioblastomas. Still, magnetic resonance imaging, computed tomography, and positron emission tomography are the most commonly used imaging methods. In this literature review, the three different types of imaging are analyzed based on the preparation before imaging by the patient, the methods by which the images are created, the risks involved, and the technological advances in each category. The technological advances also included tools that combined two types of cancer imaging into one. The attributes of each imaging type are then analyzed to see which imaging methods are most effective and how they can be used to create better patient outcomes. Through this review, it was seen that all three methods of imaging were effective in their own ways, but the decision for which tool was based on what stage the cancer was in.
ContributorsRallapalli, Divya (Author) / Lan, Shiwei (Thesis director) / Aliste, Marcela (Committee member) / Barrett, The Honors College (Contributor)
Created2024-05
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Description
Octopus arms employ a complex three dimensional array of musculature, called a
muscular hydrostat, which allows for nearly infinite degrees of freedom of movement without
the structure of a skeletal system. This study employed Magnetic Resonance Imaging with a
Gadoteridol-based contrast agent to image the octopus arm and view the internal tissues. Muscle
layering

Octopus arms employ a complex three dimensional array of musculature, called a
muscular hydrostat, which allows for nearly infinite degrees of freedom of movement without
the structure of a skeletal system. This study employed Magnetic Resonance Imaging with a
Gadoteridol-based contrast agent to image the octopus arm and view the internal tissues. Muscle
layering was mapped and area was measured using AMIRA image processing and the trends in
these layers at the proximal, middle, and distal portions of the arms were analyzed. A total of 39
arms from 6 specimens were scanned to give 112 total imaged sections (38 proximal, 37 middle,
37 distal), from which to ascertain and study the possible differences in musculature. The
images revealed significant increases in the internal longitudinal muscle layer percentages
between the proximal and middle, proximal and distal, and middle and distal sections of the
arms. These structural differences are hypothesized to be used for rapid retraction of the distal
segment when encountering predators or noxious stimuli. In contrast, a significant decrease in
the transverse muscle layer was found when comparing the same sections. These structural
differences are hypothesized to be a result of bending behaviors during retraction. Additionally,
the internal longitudinal layer was separately studied orally, toward the sucker, and aborally,
away from the sucker. The significant differences in oral and aboral internal longitudinal
musculature in proximal, middle, and distal sections is hypothesized to support the pseudo-joint
functionality displayed in octopus fetching behaviors. The results indicate that individual
octopus arm morphology is more unique than previously thought and supports that internal
structural differences exist to support behavioral functionality.
ContributorsCummings, Sheldon Daniel (Author) / Fisher, Rebecca (Thesis director) / Marvi, Hamidreza (Committee member) / Cherry, Brian (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05